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Circulating cell-free DNA analyses for Patient Monitoring in Small Cell Lung Cancer

This study consists of over 200 data files from cfDNA and germline DNA from 69 patients and 32 healthy normal volunteers discussed in this publication.

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CRUK Cancer Biomarker Centre (CBC) EGA Policy for The SCLC cfDNA Study

Policy: CR-UK Manchester Institute Cancer Biomarker Centre DATA ACCESS AGREEMENT This agreement governs the terms on which access will be granted to the genomic data generated by the Cancer Biomarker Centre, CR-UK Manchester Institute. In signing this agreement, You are agreeing to be bound by the terms and conditions of access set out in this agreement. For the sake of clarity, the terms of access set out in this agreement apply both to the User and the User’s Institution (as defined below). User Institution and User are referred to within the agreement as “You” and “Your” shall be construed accordingly. Definitions: CBC means the Cancer Biomarker Centre, a CR-UK funded laboratory within the CR-UK Manchester Institute. Data means all and any human genetic data obtained from CBC. Data Subject means a person, who has been informed of the purpose for which the Data is held and has given his/her informed consent thereto. User means a researcher whose User Institution has previously completed this Data Access Agreement and has received acknowledgement of its acceptance. Publications means, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. User Institution means the organisation at which the User is employed, affiliated or enrolled. Terms and Conditions: In signing this Agreement: 1. You agree to use the Data only for the advancement of medical research, according to the consent obtained from sample donors. 2. You agree not to use the data or any part thereof for the creation of products for sale or for any commercial purpose. 3. You agree to preserve, at all times, the confidentiality of information and Data pertaining to Data Subjects. In particular, You undertake not to use, or attempt to use the Data to compromise or otherwise infringe the confidentiality of information on Data Subjects and their right to privacy. 4. You agree not to attempt to link the data provided under this agreement to other information or archive data available for the data sets provided, even if access to that data has been formally granted to you, or it is freely available without restriction, without specific permission being sought from the relevant access committees. 5. You agree not to transfer or disclose the Data, in whole or part, or any identifiable material derived from the Data, to others, except as necessary for data/safety monitoring or programme management. Should You wish to share the Data with a collaborator outwith the same Institution, the third party must make a separate application for access to the Data. 6. You agree to use the data for the approved purpose and project described in your application; use of the data for a new purpose or project will require a new application and approval. 7. You accept that Data will be reissued from time to time, with suitable versioning. If the reissue is at the request of sample donors and/or other ethical scrutiny, You will destroy earlier versions of the Data. 8. You agree to abide by the terms outlined in the 'Publications Policy' as set out in Schedule 1. 9. You agree to acknowledge in any work based in whole or part on the Data, the published paper from which the Data derives, the version of the data, and the role of CBC and the relevant primary collectors and their funders. Suitable wording is provided in the Publications Policy given in Schedule 1. 10. You accept that CBC, the original data creators, depositors or copyright holders, or the funders of the Data or any part of the Data supplied: a) bear no legal responsibility for the accuracy or comprehensiveness of the Data; and b) accept no liability for indirect, consequential, or incidental, damages or losses arising from use of the Data, or from the unavailability of, or break in access to, the Data for whatever reason. 11. You understand and acknowledge that the Data is protected by copyright and other intellectual property rights, and that duplication, except as reasonably required to carry out Your research with the Data, or sale of all or part of the Data on any media is not permitted. 12. You recognise that nothing in this agreement shall operate to transfer to the User Institution any intellectual property rights relating to the Data. The User Institution has the right to develop intellectual property based on comparisons with their own data. 13. You accept that this agreement will terminate immediately upon any breach of this agreement by You and You will be required to destroy any Data held. 14. You accept that it may be necessary for CBC or its appointed agent to alter the terms of this agreement from time to time in order to address new concerns. In this event, CBC or its appointed agent will contact You to inform You of any changes and You agree that Your continued use of the Data shall be dependent on the parties entering into a new version of the Agreement. 15. You agree that you will submit a report to the Data Access Committee, if requested, on completion of the agreed purpose. The Data Access Committee agrees to treat the report and all information, data, results, and conclusions contained within such report as confidential information belonging to the User Institution. 16. You accept that the Data is protected by and subject to international laws, including but not limited to the UK Data Protection Act 1998, and that You are responsible for ensuring compliance with any such applicable law. The Data Access Committee reserves the right to request and inspect data security and management documentation to ensure the adequacy of data protection measures in countries that have no national laws comparable to that which pertain in the EAA. 17. This agreement shall be construed, interpreted and governed by the laws of England and Wales and shall be subject to the non-exclusive jurisdiction of the English courts. SCHEDULE 1 Publications Policy The primary aim of CBC is to gain a greater understanding of the fundamental basis of how cancer develops and apply that knowledge to develop new diagnostic tests, potential treatments and better ways to predict the outcomes. Authors who use data from the project must acknowledge CBC using the following wording "This study makes use of data generated by CRUK Cancer Biomarker Centre (CBC), CR-UK Manchester Institute (http://www.cruk.manchester.ac.uk). Funding for the project was provided by core funding to CRUK Manchester Institute (C5759/A27412), the Manchester CRUK Centre Award (C5759/A25254) and via the CRUK Manchester Experimental Cancer Medicines Centre (A20465)" and cite the relevant primary publication. Users should note that CBC bears no responsibility for the further analysis or interpretation of these data, over and above that published by CBC.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001003110 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00005101778 fastq.gz 177.3 MB
EGAF00005101779 fastq.gz 185.6 MB
EGAF00005103350 fastq.gz 260.7 MB
EGAF00005103351 fastq.gz 270.6 MB
EGAF00005103352 fastq.gz 152.6 MB
EGAF00005103353 fastq.gz 159.0 MB
EGAF00005103354 fastq.gz 131.0 MB
EGAF00005103355 fastq.gz 137.4 MB
EGAF00005103356 fastq.gz 183.1 MB
EGAF00005103357 fastq.gz 192.9 MB
EGAF00005103358 fastq.gz 229.8 MB
EGAF00005103359 fastq.gz 235.5 MB
EGAF00005103360 fastq.gz 104.0 MB
EGAF00005103361 fastq.gz 108.8 MB
EGAF00005103362 fastq.gz 167.1 MB
EGAF00005103363 fastq.gz 174.1 MB
EGAF00005103364 fastq.gz 170.7 MB
EGAF00005103365 fastq.gz 176.1 MB
EGAF00005103366 fastq.gz 177.3 MB
EGAF00005103367 fastq.gz 185.7 MB
EGAF00005103368 fastq.gz 231.4 MB
EGAF00005103369 fastq.gz 238.3 MB
EGAF00005103370 fastq.gz 180.7 MB
EGAF00005103371 fastq.gz 191.8 MB
EGAF00005103372 fastq.gz 115.5 MB
EGAF00005103373 fastq.gz 120.0 MB
EGAF00005103374 fastq.gz 248.5 MB
EGAF00005103375 fastq.gz 258.3 MB
EGAF00005103376 fastq.gz 259.5 MB
EGAF00005103377 fastq.gz 271.2 MB
EGAF00005103378 fastq.gz 264.1 MB
EGAF00005103379 fastq.gz 275.2 MB
EGAF00005103380 fastq.gz 272.3 MB
EGAF00005103381 fastq.gz 279.2 MB
EGAF00005103382 fastq.gz 196.7 MB
EGAF00005103383 fastq.gz 203.8 MB
EGAF00005103384 fastq.gz 226.5 MB
EGAF00005103385 fastq.gz 239.0 MB
EGAF00005103386 fastq.gz 160.1 MB
EGAF00005103387 fastq.gz 168.7 MB
EGAF00005103388 fastq.gz 190.4 MB
EGAF00005103389 fastq.gz 199.8 MB
EGAF00005103390 fastq.gz 214.9 MB
EGAF00005103391 fastq.gz 226.2 MB
EGAF00005103392 fastq.gz 216.7 MB
EGAF00005103393 fastq.gz 225.2 MB
EGAF00005103394 fastq.gz 498.7 MB
EGAF00005103395 fastq.gz 519.0 MB
EGAF00005103396 fastq.gz 280.0 MB
EGAF00005103397 fastq.gz 292.3 MB
EGAF00005103398 fastq.gz 299.0 MB
EGAF00005103399 fastq.gz 318.5 MB
EGAF00005103400 fastq.gz 214.4 MB
EGAF00005103401 fastq.gz 222.5 MB
EGAF00005103402 fastq.gz 184.6 MB
EGAF00005103403 fastq.gz 191.7 MB
EGAF00005103404 fastq.gz 243.5 MB
EGAF00005103405 fastq.gz 256.2 MB
EGAF00005103406 fastq.gz 289.1 MB
EGAF00005103407 fastq.gz 301.5 MB
EGAF00005103408 fastq.gz 220.7 MB
EGAF00005103409 fastq.gz 230.8 MB
EGAF00005103410 fastq.gz 90.7 MB
EGAF00005103411 fastq.gz 93.5 MB
EGAF00005103412 fastq.gz 149.4 MB
EGAF00005103413 fastq.gz 154.6 MB
EGAF00005103414 fastq.gz 135.2 MB
EGAF00005103415 fastq.gz 140.2 MB
EGAF00005103416 fastq.gz 112.7 MB
EGAF00005103417 fastq.gz 117.8 MB
EGAF00005103418 fastq.gz 92.8 MB
EGAF00005103419 fastq.gz 95.8 MB
EGAF00005103420 fastq.gz 178.3 MB
EGAF00005103421 fastq.gz 182.9 MB
EGAF00005103422 fastq.gz 176.0 MB
EGAF00005103423 fastq.gz 185.3 MB
EGAF00005103424 fastq.gz 135.1 MB
EGAF00005103425 fastq.gz 139.9 MB
EGAF00005103426 fastq.gz 235.3 MB
EGAF00005103427 fastq.gz 242.6 MB
EGAF00005103428 fastq.gz 301.5 MB
EGAF00005103429 fastq.gz 308.8 MB
EGAF00005103430 fastq.gz 210.2 MB
EGAF00005103431 fastq.gz 215.4 MB
EGAF00005103432 fastq.gz 192.5 MB
EGAF00005103433 fastq.gz 199.6 MB
EGAF00005103434 fastq.gz 209.9 MB
EGAF00005103435 fastq.gz 216.2 MB
EGAF00005103436 fastq.gz 195.3 MB
EGAF00005103437 fastq.gz 202.2 MB
EGAF00005103438 fastq.gz 142.2 MB
EGAF00005103439 fastq.gz 146.7 MB
EGAF00005103440 fastq.gz 201.5 MB
EGAF00005103441 fastq.gz 207.5 MB
EGAF00005103442 fastq.gz 177.8 MB
EGAF00005103443 fastq.gz 184.9 MB
EGAF00005103444 fastq.gz 280.7 MB
EGAF00005103445 fastq.gz 294.9 MB
EGAF00005103446 fastq.gz 334.5 MB
EGAF00005103447 fastq.gz 355.8 MB
EGAF00005103448 fastq.gz 219.5 MB
EGAF00005103449 fastq.gz 225.7 MB
EGAF00005103450 fastq.gz 157.6 MB
EGAF00005103451 fastq.gz 167.3 MB
EGAF00005103452 fastq.gz 282.3 MB
EGAF00005103453 fastq.gz 291.4 MB
EGAF00005103454 fastq.gz 322.4 MB
EGAF00005103455 fastq.gz 336.6 MB
EGAF00005103456 fastq.gz 394.2 MB
EGAF00005103457 fastq.gz 412.3 MB
EGAF00005103458 fastq.gz 342.5 MB
EGAF00005103459 fastq.gz 360.2 MB
EGAF00005103460 fastq.gz 437.3 MB
EGAF00005103461 fastq.gz 463.8 MB
EGAF00005103462 fastq.gz 389.1 MB
EGAF00005103463 fastq.gz 411.1 MB
EGAF00005103464 fastq.gz 259.7 MB
EGAF00005103465 fastq.gz 271.0 MB
EGAF00005103466 fastq.gz 325.4 MB
EGAF00005103467 fastq.gz 341.4 MB
EGAF00005103468 fastq.gz 288.6 MB
EGAF00005103469 fastq.gz 303.8 MB
EGAF00005103470 fastq.gz 303.2 MB
EGAF00005103471 fastq.gz 319.7 MB
EGAF00005103472 fastq.gz 163.5 MB
EGAF00005103473 fastq.gz 171.1 MB
EGAF00005103474 fastq.gz 150.0 MB
EGAF00005103475 fastq.gz 157.4 MB
EGAF00005103476 fastq.gz 211.6 MB
EGAF00005103477 fastq.gz 224.2 MB
EGAF00005103478 fastq.gz 147.2 MB
EGAF00005103479 fastq.gz 157.7 MB
EGAF00005103480 fastq.gz 254.1 MB
EGAF00005103481 fastq.gz 266.9 MB
EGAF00005103482 fastq.gz 314.6 MB
EGAF00005103483 fastq.gz 326.8 MB
EGAF00005103484 fastq.gz 203.5 MB
EGAF00005103485 fastq.gz 214.9 MB
EGAF00005103486 fastq.gz 251.4 MB
EGAF00005103487 fastq.gz 260.6 MB
EGAF00005103488 fastq.gz 365.5 MB
EGAF00005103489 fastq.gz 371.9 MB
142 Files (32.9 GB)