Dataset

RNAseq Iron-Treated iPSC-derived Microglia

Dataset ID Technology Samples
EGAD00001008660 Illumina NovaSeq 6000 24

Dataset Description

Iron accumulation in microglia has been observed in Alzheimer’s disease and other neurodegenerative disorders and is thought to contribute to disease progression through various mechanisms including neuroinflammation. To study the interaction between iron accumulation and inflammation, we treated human induced pluripotent stem cell-derived microglia (iPSC-MG) with an increasing concentration of iron, in combination with inflammatory stimuli such as interferon gamma and amyloid β, and performed RNA sequencing.

Who controls access to this dataset

For each dataset that requires controlled access, there is a corresponding Data Access Committee (DAC) who determine access permissions. Access to actual data files is not managed by the EGA. If you need to request access to this data set, please contact:

DAC: RNAseq Iron-Treated iPSC-derived Microglia
Contact person: Willeke van Roon-Mom
Email: w [dot] m [dot] c [dot] van_roon [at] lumc [dot] nl
More details: EGAC00001002605

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