RNAseq Iron-Treated iPSC-derived Microglia
Iron accumulation in microglia has been observed in Alzheimer’s disease and other neurodegenerative disorders and is thought to contribute to disease progression through various mechanisms including neuroinflammation. To study the interaction between iron accumulation and inflammation, we treated human induced pluripotent stem cell-derived microglia (iPSC-MG) with an increasing concentration of iron, in combination with inflammatory stimuli such as interferon gamma and amyloid β, and performed RNA sequencing.
- 24 samples
- DAC: EGAC00001002605
- Technology: Illumina NovaSeq 6000
Policy: RNAseq Iron-Treated iPSC-derived Microglia
Restricted access because the study concerns patient data which should not be traced back to the patients. We will require citation plus acknowledgement.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
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