About file location

As the EGA is co-managed by the EMBL-EBI and CRG, files could be located in the UK and/or Spain, as indicated by their respective flags.

Alternatively, files could be located in one of the international Federated EGA nodes, as indicated next to the node's flag.
Need Help?

Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G4C2)n expression in C9orf72 ALS/FTD

To investigate the mode of action and potential side-effects we analyzed differential gene expression in Postmitotic C9orf72 iPSC-Neurons by RNAseq. The cells were treated in a 2 dose regime at 10 µm in 0.1 % DMSO for 9 days. Compound treated iPSC-Neurons were washed with PBS, frozen on dry ice and stored at -80°C until RNA isolation. The RNA was isolated using miRNA Mini Kit (Qiagen) using 700 μl of Qiazol. A total of 250 ng of RNA per sample was processed for mRNA library preparation as per the manufacturer’s instructions for Illumina® Stranded mRNA Prep Ligation to be used with the IDT® for Illumina® RNA UD Indexes Set B and sequenced using NextSeq 500/550 High Output Kit v2.5 (Illumina) on NextSeq 550 (Illumina). The data was processed and analyzed using CLC genomics workbench (Version 21.0.3, Qiagen)

Request Access

The complete study is being published in a peer-review study and hence the data is available after the associated research paper is published.

The complete study is being published in a peer-review study and hence the data is available after the associated research paper is published.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001006138 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
i
EGAF00006134176 fastq.gz 1.1 GB Report
EGAF00006134177 fastq.gz 1.2 GB Report
EGAF00006134178 fastq.gz 954.5 MB Report
EGAF00006134179 fastq.gz 972.3 MB Report
EGAF00006134180 fastq.gz 902.2 MB Report
EGAF00006134181 fastq.gz 912.4 MB Report
EGAF00006134182 fastq.gz 992.2 MB Report
EGAF00006134183 fastq.gz 1.0 GB Report
EGAF00006134184 fastq.gz 1.0 GB Report
EGAF00006134185 fastq.gz 1.0 GB Report
EGAF00006134186 fastq.gz 908.3 MB Report
EGAF00006134187 fastq.gz 908.5 MB Report
EGAF00006134188 fastq.gz 987.1 MB Report
EGAF00006134189 fastq.gz 994.9 MB Report
EGAF00006134190 fastq.gz 1.0 GB Report
EGAF00006134191 fastq.gz 1.0 GB Report
EGAF00006134192 fastq.gz 966.0 MB Report
EGAF00006134193 fastq.gz 976.6 MB Report
EGAF00006134194 fastq.gz 998.6 MB Report
EGAF00006134195 fastq.gz 995.6 MB Report
EGAF00006134196 fastq.gz 1.0 GB Report
EGAF00006134197 fastq.gz 1.0 GB Report
EGAF00006134198 fastq.gz 916.8 MB Report
EGAF00006134199 fastq.gz 926.0 MB Report
EGAF00006134200 fastq.gz 911.6 MB Report
EGAF00006134201 fastq.gz 921.9 MB Report
EGAF00006134202 fastq.gz 991.1 MB Report
EGAF00006134203 fastq.gz 998.3 MB Report
EGAF00006134204 fastq.gz 860.2 MB Report
EGAF00006134205 fastq.gz 863.0 MB Report
EGAF00006134206 fastq.gz 754.1 MB Report
EGAF00006134207 fastq.gz 762.0 MB Report
EGAF00006134208 fastq.gz 949.4 MB Report
EGAF00006134209 fastq.gz 961.0 MB Report
EGAF00006134210 fastq.gz 965.5 MB Report
EGAF00006134211 fastq.gz 972.1 MB Report
EGAF00006134212 fastq.gz 952.1 MB Report
EGAF00006134213 fastq.gz 946.8 MB Report
EGAF00006134214 fastq.gz 919.9 MB Report
EGAF00006134215 fastq.gz 931.8 MB Report
EGAF00006134216 fastq.gz 903.9 MB Report
EGAF00006134217 fastq.gz 912.0 MB Report
EGAF00006134218 fastq.gz 884.4 MB Report
EGAF00006134219 fastq.gz 895.2 MB Report
EGAF00006134220 fastq.gz 923.7 MB Report
EGAF00006134221 fastq.gz 929.8 MB Report
EGAF00006134222 fastq.gz 977.8 MB Report
EGAF00006134223 fastq.gz 986.3 MB Report
EGAF00006134224 fastq.gz 1.1 GB Report
EGAF00006134225 fastq.gz 1.1 GB Report
EGAF00006134226 fastq.gz 894.8 MB Report
EGAF00006134227 fastq.gz 900.1 MB Report
EGAF00006134228 fastq.gz 1.0 GB Report
EGAF00006134229 fastq.gz 1.0 GB Report
54 Files (51.9 GB)