Need Help?

WCDT deep RNA-seq

This dataset includes fastq files for total RNAseq of 104 patient biopsies with metastatic castration resistant prostate cancer. The RNAseq libraries were rRNA depleted and sequenced at 150bp paired-end on Illumina Novaseq.

Request Access

Data access policy for the deep RNAseq data of the WCDT cohort.

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorised Personnel: The individuals at the User Institution to whom THE WEST COAST DREAM TEAM INVESTIGATORS grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: THE WEST COAST DREAM TEAM INVESTIGATORS and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify THE WEST COAST DREAM TEAM INVESTIGATORS within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify THE WEST COAST DREAM TEAM INVESTIGATORS prior to any significant changes to the protocol for the Project. 14. The User Institution will notify THE WEST COAST DREAM TEAM INVESTIGATORS as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. THE WEST COAST DREAM TEAM INVESTIGATORS may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. As an example, this may include specific provisions relating to the Data required by Data Producers other than THE WEST COAST DREAM TEAM INVESTIGATORS. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of the United States and shall be subject to the exclusive jurisdiction of United States courts. Agreed for User Institution Signature: Name: Title: Date: Principal Investigator I confirm that I have read and understood this Agreement. Signature: Name: Title: Date: Agreed for THE WEST COAST DREAM TEAM INVESTIGATORS Signature: Name: Title: Date: APPENDIX I – DATASET DETAILS APPENDIX II ––PROJECT DETAILS APPENDIX III –– PUBLICATION POLICY APPENDIX I – DATASET DETAILS (to be completed by the data producer before passing to applicant) Dataset reference (EGA Study ID and Dataset Details) RNA sequence data from 226 advanced prostate tumors. Name of project that created the dataset The West Coast Dream Team Names of other data producers/collaborators Dr. Eric Small Dr. Felix Feng David Quigley, PhD Specific limitations on areas of research Minimum protection measures required File access: Data can be held in unencrypted files on an institutional compute system, with Unix user group read/write access for one or more appropriate groups but not Unix world read/write access behind a secure firewall. Laptops holding these data should have password protected logins and screenlocks (set to lock after 5 min of inactivity). If held on USB keys or other portable hard drives, the data must be encrypted. APPENDIX II – PROJECT DETAILS (to be completed by the Requestor) Details of dataset requested i.e., EGA Study and Dataset Accession Number Brief abstract of the Project in which the Data will be used (500 words max) All Individuals who the User Institution to be named as registered users Name of Registered User Email Job Title Supervisor* All Individuals that should have an account created at the EGA Name of Registered User Email Job Title APPENDIX III – PUBLICATION POLICY THE WEST COAST DREAM TEAM INVESTIGATORS intend to publish the results of their analysis of this dataset and do not consider its deposition into public databases to be the equivalent of such publications. THE WEST COAST DREAM TEAM INVESTIGATORS anticipate that the dataset could be useful to other qualified researchers for a variety of purposes. However, some areas of work are subject to a publication moratorium. The publication moratorium covers any publications (including oral communications) that describe the use of the dataset. For research papers, submission for publication should not occur until XX months after these data were first made available on the relevant hosting database, unless THE WEST COAST DREAM TEAM INVESTIGATORS has provided written consent to earlier submission. In any publications based on these data, please describe how the data can be accessed, including the name of the hosting database (e.g., The European Genome-phenome Archive at the European Bioinformatics Institute) and its accession numbers (e.g., EGAS00000000029), and acknowledge its use in a form agreed by the User Institution with THE WEST COAST DREAM TEAM INVESTIGATORS.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001006275 RNASeq

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00006173441 fastq.gz 37.5 GB
EGAF00006173442 fastq.gz 39.5 GB
EGAF00006173443 fastq.gz 76.5 GB
EGAF00006173444 fastq.gz 81.3 GB
EGAF00006173445 fastq.gz 66.8 GB
EGAF00006173446 fastq.gz 69.9 GB
EGAF00006173447 fastq.gz 26.3 GB
EGAF00006173448 fastq.gz 27.8 GB
EGAF00006173449 fastq.gz 31.9 GB
EGAF00006173450 fastq.gz 32.8 GB
EGAF00006173451 fastq.gz 30.9 GB
EGAF00006173452 fastq.gz 33.0 GB
EGAF00006173453 fastq.gz 22.9 GB
EGAF00006173454 fastq.gz 24.4 GB
EGAF00006173455 fastq.gz 35.9 GB
EGAF00006173456 fastq.gz 38.1 GB
EGAF00006173457 fastq.gz 27.5 GB
EGAF00006173458 fastq.gz 29.1 GB
EGAF00006173459 fastq.gz 27.2 GB
EGAF00006173460 fastq.gz 28.8 GB
EGAF00006173461 fastq.gz 27.6 GB
EGAF00006173462 fastq.gz 29.4 GB
EGAF00006173463 fastq.gz 63.1 GB
EGAF00006173464 fastq.gz 66.0 GB
EGAF00006173465 fastq.gz 28.5 GB
EGAF00006173466 fastq.gz 30.5 GB
EGAF00006173467 fastq.gz 28.1 GB
EGAF00006173468 fastq.gz 30.0 GB
EGAF00006173469 fastq.gz 39.8 GB
EGAF00006173470 fastq.gz 41.0 GB
EGAF00006173471 fastq.gz 67.8 GB
EGAF00006173472 fastq.gz 71.1 GB
EGAF00006173473 fastq.gz 32.2 GB
EGAF00006173474 fastq.gz 33.4 GB
EGAF00006173475 fastq.gz 30.8 GB
EGAF00006173476 fastq.gz 31.8 GB
EGAF00006173477 fastq.gz 22.7 GB
EGAF00006173478 fastq.gz 24.1 GB
EGAF00006173479 fastq.gz 32.0 GB
EGAF00006173480 fastq.gz 34.3 GB
EGAF00006173481 fastq.gz 43.5 GB
EGAF00006173482 fastq.gz 45.6 GB
EGAF00006173483 fastq.gz 31.6 GB
EGAF00006173484 fastq.gz 33.8 GB
EGAF00006173485 fastq.gz 38.5 GB
EGAF00006173486 fastq.gz 40.9 GB
EGAF00006173487 fastq.gz 33.7 GB
EGAF00006173488 fastq.gz 35.4 GB
EGAF00006173489 fastq.gz 27.4 GB
EGAF00006173490 fastq.gz 28.9 GB
EGAF00006173491 fastq.gz 29.3 GB
EGAF00006173492 fastq.gz 30.6 GB
EGAF00006173493 fastq.gz 31.6 GB
EGAF00006173494 fastq.gz 33.4 GB
EGAF00006173495 fastq.gz 32.5 GB
EGAF00006173496 fastq.gz 34.5 GB
EGAF00006173497 fastq.gz 29.3 GB
EGAF00006173498 fastq.gz 30.9 GB
EGAF00006173499 fastq.gz 36.4 GB
EGAF00006173500 fastq.gz 38.8 GB
EGAF00006173501 fastq.gz 24.7 GB
EGAF00006173502 fastq.gz 25.9 GB
EGAF00006173503 fastq.gz 35.4 GB
EGAF00006173504 fastq.gz 37.0 GB
EGAF00006173505 fastq.gz 32.0 GB
EGAF00006173506 fastq.gz 33.7 GB
EGAF00006173507 fastq.gz 39.2 GB
EGAF00006173508 fastq.gz 41.5 GB
EGAF00006173509 fastq.gz 34.4 GB
EGAF00006173510 fastq.gz 36.3 GB
EGAF00006173511 fastq.gz 32.1 GB
EGAF00006173512 fastq.gz 34.1 GB
EGAF00006173513 fastq.gz 34.5 GB
EGAF00006173514 fastq.gz 35.6 GB
EGAF00006173515 fastq.gz 28.4 GB
EGAF00006173516 fastq.gz 29.3 GB
EGAF00006173517 fastq.gz 34.9 GB
EGAF00006173518 fastq.gz 36.8 GB
EGAF00006173519 fastq.gz 43.5 GB
EGAF00006173520 fastq.gz 45.5 GB
EGAF00006173521 fastq.gz 33.7 GB
EGAF00006173522 fastq.gz 35.9 GB
EGAF00006173523 fastq.gz 46.2 GB
EGAF00006173524 fastq.gz 48.5 GB
EGAF00006173525 fastq.gz 25.6 GB
EGAF00006173526 fastq.gz 27.1 GB
EGAF00006173527 fastq.gz 38.9 GB
EGAF00006173528 fastq.gz 40.8 GB
EGAF00006173529 fastq.gz 38.4 GB
EGAF00006173530 fastq.gz 39.6 GB
EGAF00006173531 fastq.gz 28.0 GB
EGAF00006173532 fastq.gz 29.9 GB
EGAF00006173533 fastq.gz 29.6 GB
EGAF00006173534 fastq.gz 31.1 GB
EGAF00006173535 fastq.gz 26.1 GB
EGAF00006173536 fastq.gz 27.5 GB
EGAF00006173537 fastq.gz 34.5 GB
EGAF00006173538 fastq.gz 36.6 GB
EGAF00006173539 fastq.gz 30.4 GB
EGAF00006173540 fastq.gz 32.4 GB
EGAF00006173541 fastq.gz 22.4 GB
EGAF00006173542 fastq.gz 23.6 GB
EGAF00006173543 fastq.gz 32.2 GB
EGAF00006173544 fastq.gz 33.9 GB
EGAF00006173545 fastq.gz 32.3 GB
EGAF00006173546 fastq.gz 33.9 GB
EGAF00006173547 fastq.gz 39.3 GB
EGAF00006173548 fastq.gz 41.1 GB
EGAF00006173549 fastq.gz 50.6 GB
EGAF00006173550 fastq.gz 53.7 GB
EGAF00006173551 fastq.gz 22.7 GB
EGAF00006173552 fastq.gz 23.8 GB
EGAF00006173553 fastq.gz 29.3 GB
EGAF00006173554 fastq.gz 31.2 GB
EGAF00006173555 fastq.gz 35.4 GB
EGAF00006173556 fastq.gz 37.0 GB
EGAF00006173557 fastq.gz 26.3 GB
EGAF00006173558 fastq.gz 27.6 GB
EGAF00006173559 fastq.gz 29.9 GB
EGAF00006173560 fastq.gz 31.5 GB
EGAF00006173561 fastq.gz 34.8 GB
EGAF00006173562 fastq.gz 36.5 GB
EGAF00006173563 fastq.gz 32.7 GB
EGAF00006173564 fastq.gz 35.5 GB
EGAF00006173565 fastq.gz 30.4 GB
EGAF00006173566 fastq.gz 32.3 GB
EGAF00006173567 fastq.gz 43.9 GB
EGAF00006173568 fastq.gz 46.1 GB
EGAF00006173569 fastq.gz 39.6 GB
EGAF00006173570 fastq.gz 41.3 GB
EGAF00006173571 fastq.gz 36.0 GB
EGAF00006173572 fastq.gz 37.3 GB
EGAF00006173573 fastq.gz 43.5 GB
EGAF00006173574 fastq.gz 45.3 GB
EGAF00006173575 fastq.gz 39.2 GB
EGAF00006173576 fastq.gz 41.0 GB
EGAF00006173577 fastq.gz 34.9 GB
EGAF00006173578 fastq.gz 36.6 GB
EGAF00006173579 fastq.gz 32.3 GB
EGAF00006173580 fastq.gz 34.4 GB
EGAF00006173581 fastq.gz 32.5 GB
EGAF00006173582 fastq.gz 34.2 GB
EGAF00006173583 fastq.gz 38.9 GB
EGAF00006173584 fastq.gz 41.1 GB
EGAF00006173585 fastq.gz 38.5 GB
EGAF00006173586 fastq.gz 40.1 GB
EGAF00006173587 fastq.gz 32.4 GB
EGAF00006173588 fastq.gz 33.7 GB
EGAF00006173589 fastq.gz 31.9 GB
EGAF00006173590 fastq.gz 33.3 GB
EGAF00006173591 fastq.gz 32.8 GB
EGAF00006173592 fastq.gz 35.1 GB
EGAF00006173593 fastq.gz 32.1 GB
EGAF00006173594 fastq.gz 34.2 GB
EGAF00006173595 fastq.gz 23.6 GB
EGAF00006173596 fastq.gz 25.3 GB
EGAF00006173597 fastq.gz 19.7 GB
EGAF00006173598 fastq.gz 20.9 GB
EGAF00006173599 fastq.gz 29.8 GB
EGAF00006173600 fastq.gz 31.3 GB
EGAF00006173601 fastq.gz 31.2 GB
EGAF00006173602 fastq.gz 32.9 GB
EGAF00006173603 fastq.gz 32.9 GB
EGAF00006173604 fastq.gz 35.0 GB
EGAF00006173605 fastq.gz 32.4 GB
EGAF00006173606 fastq.gz 34.0 GB
EGAF00006173607 fastq.gz 15.0 GB
EGAF00006173608 fastq.gz 15.8 GB
EGAF00006173609 fastq.gz 22.7 GB
EGAF00006173610 fastq.gz 24.0 GB
EGAF00006173611 fastq.gz 42.1 GB
EGAF00006173612 fastq.gz 43.8 GB
EGAF00006173613 fastq.gz 25.7 GB
EGAF00006173614 fastq.gz 27.8 GB
EGAF00006173615 fastq.gz 47.7 GB
EGAF00006173616 fastq.gz 50.2 GB
EGAF00006173617 fastq.gz 33.4 GB
EGAF00006173618 fastq.gz 35.4 GB
EGAF00006173619 fastq.gz 21.0 GB
EGAF00006173620 fastq.gz 22.1 GB
EGAF00006173621 fastq.gz 21.1 GB
EGAF00006173622 fastq.gz 22.3 GB
EGAF00006173623 fastq.gz 23.3 GB
EGAF00006173624 fastq.gz 25.0 GB
EGAF00006173625 fastq.gz 36.7 GB
EGAF00006173626 fastq.gz 38.5 GB
EGAF00006173627 fastq.gz 19.2 GB
EGAF00006173628 fastq.gz 20.3 GB
EGAF00006173629 fastq.gz 23.9 GB
EGAF00006173630 fastq.gz 24.9 GB
EGAF00006173631 fastq.gz 22.3 GB
EGAF00006173632 fastq.gz 23.8 GB
EGAF00006173633 fastq.gz 29.7 GB
EGAF00006173634 fastq.gz 31.3 GB
EGAF00006173635 fastq.gz 28.1 GB
EGAF00006173636 fastq.gz 29.4 GB
EGAF00006173637 fastq.gz 29.2 GB
EGAF00006173638 fastq.gz 30.6 GB
EGAF00006173639 fastq.gz 30.4 GB
EGAF00006173640 fastq.gz 31.7 GB
EGAF00006173641 fastq.gz 36.9 GB
EGAF00006173642 fastq.gz 38.7 GB
EGAF00006173643 fastq.gz 31.7 GB
EGAF00006173644 fastq.gz 33.0 GB
EGAF00006173645 fastq.gz 21.4 GB
EGAF00006173646 fastq.gz 22.7 GB
EGAF00006173647 fastq.gz 23.3 GB
EGAF00006173648 fastq.gz 24.7 GB
208 Files (7.1 TB)