Need Help?

Colorectal cancer organoid-stroma biobank cohort

In colorectal cancers (CRC) the tumor microenvironment plays a key role for prognosis and therapy efficacy. Patient-derived tumor organoids (PDTOs) show enormous potential for preclinical testing, however, purely epithelial cultures features including the ‘consensus molecular subtypes’ (CMS) are largely eradicated. To better reflect the cell type heterogeneity, we established the CRC organoid-stroma biobank of matched PDTOs and cancer-associated fibroblasts (CAFs) from 30 patients. Whole exome sequencing and transcriptome analysis in various in vitro and in vivo contexts was performed to study the influence of the TME on the CRC phenotype.

Request Access

Data access policy of organoid-stroma biobank

For access to sequencing data deposited to the European Genome-phenome Archive (EGA), application documents should be completed and returned to the Data Access Committee (DAC) of the Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy (email address: data-access@georg-speyer-haus.de). Applications will only be accepted electronically. Any queries regarding access procedures or completion of the forms should be sent to this address. Additional information on the data access procedure can be obtained on the EGA webpage (https://ega-archive.org/). Application requires the completion of the Data Access Agreement (including Appendix I, II and III) for each data set that must be signed by the legal entity with which you are affiliated (signed and stamped, no electronic signature). Additionally, the DAC needs a document providing proof that the applicant is working in a scientific organization (signed and stamped by a legal authority of the organization). In case of collaborative applications each institution has to submit its own application. User institutions located outside the EU/ EEA (European Economic Area) are requested to additionally enter into the Standard Contractual Clauses for the transfer of personal data to third countries. The form must be completed (including Annex A and B) and signed. Technical problems with the EGA download should be reported directly to the EGA Helpdesk. (helpdesk@ega-archive.org)

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001007300 Other
EGAS00001007301 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00008087774 fastq.gz 454.5 MB
EGAF00008087775 fastq.gz 1.6 GB
EGAF00008087776 fastq.gz 6.0 GB
EGAF00008087777 fastq.gz 6.1 GB
EGAF00008087778 fastq.gz 4.6 GB
EGAF00008087779 fastq.gz 4.7 GB
EGAF00008087780 fastq.gz 4.5 GB
EGAF00008087781 fastq.gz 4.6 GB
EGAF00008087782 fastq.gz 4.2 GB
EGAF00008087783 fastq.gz 4.4 GB
EGAF00008087784 fastq.gz 3.6 GB
EGAF00008087785 fastq.gz 3.5 GB
EGAF00008087786 fastq.gz 5.6 GB
EGAF00008087787 fastq.gz 5.6 GB
EGAF00008087788 fastq.gz 5.1 GB
EGAF00008087789 fastq.gz 5.2 GB
EGAF00008087790 fastq.gz 5.1 GB
EGAF00008087791 fastq.gz 5.2 GB
EGAF00008087792 fastq.gz 4.8 GB
EGAF00008087793 fastq.gz 4.9 GB
EGAF00008087794 fastq.gz 5.4 GB
EGAF00008087795 fastq.gz 5.5 GB
EGAF00008087796 fastq.gz 5.6 GB
EGAF00008087797 fastq.gz 6.1 GB
EGAF00008087798 fastq.gz 4.5 GB
EGAF00008087799 fastq.gz 5.0 GB
EGAF00008087800 fastq.gz 4.4 GB
EGAF00008087801 fastq.gz 4.8 GB
EGAF00008087802 fastq.gz 5.1 GB
EGAF00008087803 fastq.gz 5.6 GB
EGAF00008087804 fastq.gz 4.9 GB
EGAF00008087805 fastq.gz 5.4 GB
EGAF00008087806 fastq.gz 5.1 GB
EGAF00008087807 fastq.gz 5.5 GB
EGAF00008087808 fastq.gz 4.9 GB
EGAF00008087809 fastq.gz 5.4 GB
EGAF00008087810 fastq.gz 4.5 GB
EGAF00008087811 fastq.gz 4.9 GB
EGAF00008087812 fastq.gz 5.3 GB
EGAF00008087813 fastq.gz 5.9 GB
EGAF00008087814 fastq.gz 4.7 GB
EGAF00008087815 fastq.gz 5.2 GB
EGAF00008087816 fastq.gz 5.8 GB
EGAF00008087817 fastq.gz 6.4 GB
EGAF00008087818 fastq.gz 4.8 GB
EGAF00008087819 fastq.gz 5.3 GB
EGAF00008087820 fastq.gz 4.3 GB
EGAF00008087821 fastq.gz 4.9 GB
EGAF00008087822 fastq.gz 4.1 GB
EGAF00008087823 fastq.gz 4.6 GB
EGAF00008087824 fastq.gz 4.8 GB
EGAF00008087825 fastq.gz 5.2 GB
EGAF00008087826 fastq.gz 4.9 GB
EGAF00008087827 fastq.gz 5.3 GB
EGAF00008087828 fastq.gz 5.0 GB
EGAF00008087829 fastq.gz 5.4 GB
EGAF00008087830 fastq.gz 5.6 GB
EGAF00008087831 fastq.gz 6.2 GB
EGAF00008087832 fastq.gz 4.9 GB
EGAF00008087833 fastq.gz 5.3 GB
EGAF00008087834 fastq.gz 5.0 GB
EGAF00008087835 fastq.gz 5.3 GB
EGAF00008087836 fastq.gz 6.0 GB
EGAF00008087837 fastq.gz 6.3 GB
EGAF00008087838 fastq.gz 5.9 GB
EGAF00008087839 fastq.gz 6.2 GB
EGAF00008087840 fastq.gz 5.7 GB
EGAF00008087841 fastq.gz 5.9 GB
EGAF00008087842 fastq.gz 6.8 GB
EGAF00008087843 fastq.gz 7.1 GB
EGAF00008087844 fastq.gz 6.1 GB
EGAF00008087845 fastq.gz 6.3 GB
EGAF00008087846 fastq.gz 4.8 GB
EGAF00008087847 fastq.gz 5.0 GB
EGAF00008087848 fastq.gz 5.0 GB
EGAF00008087849 fastq.gz 5.0 GB
EGAF00008087850 fastq.gz 4.8 GB
EGAF00008087851 fastq.gz 5.0 GB
EGAF00008087852 fastq.gz 5.9 GB
EGAF00008087853 fastq.gz 6.5 GB
EGAF00008087854 fastq.gz 6.8 GB
EGAF00008087855 fastq.gz 7.6 GB
EGAF00008087856 fastq.gz 5.8 GB
EGAF00008087857 fastq.gz 6.3 GB
EGAF00008087858 fastq.gz 5.0 GB
EGAF00008087859 fastq.gz 5.4 GB
EGAF00008087860 fastq.gz 6.4 GB
EGAF00008087861 fastq.gz 6.9 GB
EGAF00008087862 fastq.gz 6.8 GB
EGAF00008087863 fastq.gz 7.4 GB
EGAF00008087864 fastq.gz 4.6 GB
EGAF00008087865 fastq.gz 5.1 GB
EGAF00008087866 fastq.gz 5.2 GB
EGAF00008087867 fastq.gz 5.7 GB
EGAF00008087868 fastq.gz 4.8 GB
EGAF00008087869 fastq.gz 5.3 GB
EGAF00008087870 fastq.gz 5.1 GB
EGAF00008087871 fastq.gz 5.6 GB
EGAF00008087872 fastq.gz 6.2 GB
EGAF00008087873 fastq.gz 6.8 GB
EGAF00008087874 fastq.gz 6.6 GB
EGAF00008087875 fastq.gz 7.3 GB
EGAF00008087876 fastq.gz 6.9 GB
EGAF00008087877 fastq.gz 7.5 GB
EGAF00008087878 fastq.gz 5.8 GB
EGAF00008087879 fastq.gz 6.3 GB
EGAF00008087880 fastq.gz 6.4 GB
EGAF00008087881 fastq.gz 7.0 GB
EGAF00008087882 fastq.gz 7.4 GB
EGAF00008087883 fastq.gz 8.3 GB
EGAF00008087884 fastq.gz 5.3 GB
EGAF00008087885 fastq.gz 5.9 GB
EGAF00008087886 fastq.gz 5.0 GB
EGAF00008087887 fastq.gz 5.4 GB
EGAF00008087888 fastq.gz 5.2 GB
EGAF00008087889 fastq.gz 5.6 GB
EGAF00008087890 fastq.gz 4.7 GB
EGAF00008087891 fastq.gz 4.9 GB
EGAF00008087892 fastq.gz 4.8 GB
EGAF00008087893 fastq.gz 5.1 GB
EGAF00008087894 fastq.gz 4.5 GB
EGAF00008087895 fastq.gz 4.7 GB
EGAF00008087896 fastq.gz 4.0 GB
EGAF00008087897 fastq.gz 4.2 GB
EGAF00008087898 fastq.gz 4.7 GB
EGAF00008087899 fastq.gz 4.9 GB
EGAF00008087900 fastq.gz 4.8 GB
EGAF00008087901 fastq.gz 5.0 GB
EGAF00008087902 fastq.gz 4.9 GB
EGAF00008087903 fastq.gz 5.5 GB
EGAF00008087904 fastq.gz 4.7 GB
EGAF00008087905 fastq.gz 5.1 GB
EGAF00008087906 fastq.gz 5.6 GB
EGAF00008087907 fastq.gz 6.1 GB
EGAF00008087908 fastq.gz 4.3 GB
EGAF00008087909 fastq.gz 4.8 GB
EGAF00008087910 fastq.gz 4.9 GB
EGAF00008087911 fastq.gz 5.4 GB
EGAF00008087912 fastq.gz 4.6 GB
EGAF00008087913 fastq.gz 5.1 GB
EGAF00008087914 fastq.gz 4.2 GB
EGAF00008087915 fastq.gz 4.7 GB
EGAF00008087916 fastq.gz 5.2 GB
EGAF00008087917 fastq.gz 5.7 GB
EGAF00008087918 fastq.gz 5.0 GB
EGAF00008087919 fastq.gz 5.4 GB
EGAF00008087920 fastq.gz 4.8 GB
EGAF00008087921 fastq.gz 5.3 GB
EGAF00008087922 fastq.gz 4.9 GB
EGAF00008087923 fastq.gz 5.2 GB
EGAF00008087924 fastq.gz 5.8 GB
EGAF00008087925 fastq.gz 6.3 GB
EGAF00008087926 fastq.gz 5.1 GB
EGAF00008087927 fastq.gz 5.5 GB
EGAF00008087928 fastq.gz 4.9 GB
EGAF00008087929 fastq.gz 5.4 GB
EGAF00008087930 fastq.gz 4.5 GB
EGAF00008087931 fastq.gz 5.0 GB
EGAF00008087932 fastq.gz 5.5 GB
EGAF00008087933 fastq.gz 6.1 GB
EGAF00008087934 fastq.gz 4.6 GB
EGAF00008087935 fastq.gz 4.9 GB
EGAF00008087936 fastq.gz 5.1 GB
EGAF00008087937 fastq.gz 5.6 GB
EGAF00008087938 fastq.gz 5.1 GB
EGAF00008087939 fastq.gz 5.6 GB
EGAF00008087940 fastq.gz 5.5 GB
EGAF00008087941 fastq.gz 5.7 GB
EGAF00008101581 fastq.gz 1.1 GB
EGAF00008101582 fastq.gz 1.0 GB
EGAF00008101583 fastq.gz 1.0 GB
EGAF00008101584 fastq.gz 1.5 GB
EGAF00008101585 fastq.gz 1.0 GB
EGAF00008101586 fastq.gz 1.3 GB
EGAF00008101587 fastq.gz 869.7 MB
EGAF00008101588 fastq.gz 918.3 MB
EGAF00008101589 fastq.gz 1.1 GB
EGAF00008101590 fastq.gz 1.1 GB
EGAF00008101591 fastq.gz 1.2 GB
EGAF00008101592 fastq.gz 1.7 GB
EGAF00008101593 fastq.gz 1.3 GB
EGAF00008101594 fastq.gz 1.1 GB
EGAF00008101595 fastq.gz 1.0 GB
EGAF00008101596 fastq.gz 1.1 GB
EGAF00008101597 fastq.gz 1.1 GB
EGAF00008101598 fastq.gz 1.2 GB
EGAF00008101599 fastq.gz 1.4 GB
EGAF00008101600 fastq.gz 1.3 GB
EGAF00008101601 fastq.gz 1.2 GB
EGAF00008101602 fastq.gz 964.8 MB
EGAF00008101603 fastq.gz 997.4 MB
EGAF00008101604 fastq.gz 1.4 GB
EGAF00008101605 fastq.gz 1.4 GB
EGAF00008101606 fastq.gz 1.3 GB
EGAF00008101607 fastq.gz 1.3 GB
EGAF00008101608 fastq.gz 1.0 GB
EGAF00008101609 fastq.gz 1.3 GB
EGAF00008101610 fastq.gz 1.4 GB
EGAF00008101611 fastq.gz 1.5 GB
EGAF00008101612 fastq.gz 1.4 GB
EGAF00008101613 fastq.gz 1.0 GB
EGAF00008101614 fastq.gz 861.4 MB
EGAF00008101615 fastq.gz 1.2 GB
EGAF00008101616 fastq.gz 941.9 MB
EGAF00008101617 fastq.gz 1.7 GB
EGAF00008101618 fastq.gz 1.1 GB
EGAF00008101619 fastq.gz 1.8 GB
EGAF00008101620 fastq.gz 1.7 GB
EGAF00008101621 fastq.gz 311.7 MB
EGAF00008101622 fastq.gz 1.5 GB
EGAF00008101623 fastq.gz 791.1 MB
EGAF00008101624 fastq.gz 2.4 GB
EGAF00008101625 fastq.gz 1.7 GB
EGAF00008101626 fastq.gz 1.3 GB
EGAF00008101627 fastq.gz 1.3 GB
EGAF00008101628 fastq.gz 1.5 GB
EGAF00008101629 fastq.gz 1.4 GB
EGAF00008101630 fastq.gz 1.6 GB
EGAF00008101631 fastq.gz 1.3 GB
EGAF00008101632 fastq.gz 1.8 GB
EGAF00008101633 fastq.gz 1.4 GB
EGAF00008101634 fastq.gz 1.4 GB
EGAF00008101635 fastq.gz 1.4 GB
EGAF00008101636 fastq.gz 1.4 GB
EGAF00008101637 fastq.gz 1.2 GB
EGAF00008101638 fastq.gz 1.1 GB
EGAF00008101639 fastq.gz 1.1 GB
EGAF00008101640 fastq.gz 1.0 GB
EGAF00008101641 fastq.gz 763.9 MB
EGAF00008101642 fastq.gz 1.2 GB
EGAF00008101643 fastq.gz 853.4 MB
EGAF00008101644 fastq.gz 767.3 MB
EGAF00008101645 fastq.gz 1.7 GB
EGAF00008101646 fastq.gz 1.5 GB
EGAF00008101647 fastq.gz 1.2 GB
EGAF00008101648 fastq.gz 1.1 GB
EGAF00008101649 fastq.gz 1.0 GB
EGAF00008101650 fastq.gz 1.1 GB
EGAF00008101651 fastq.gz 707.0 MB
EGAF00008101652 fastq.gz 665.7 MB
EGAF00008101653 fastq.gz 599.9 MB
EGAF00008101654 fastq.gz 872.5 MB
EGAF00008101655 fastq.gz 716.8 MB
EGAF00008101656 fastq.gz 845.6 MB
EGAF00008101657 fastq.gz 1.1 GB
EGAF00008101658 fastq.gz 1.2 GB
EGAF00008101659 fastq.gz 1.1 GB
EGAF00008101660 fastq.gz 1.2 GB
EGAF00008101661 fastq.gz 1.3 GB
EGAF00008101662 fastq.gz 1.3 GB
EGAF00008101663 fastq.gz 1.1 GB
EGAF00008101664 fastq.gz 1.1 GB
EGAF00008101665 fastq.gz 1.0 GB
EGAF00008101666 fastq.gz 1.0 GB
EGAF00008101667 fastq.gz 1.1 GB
EGAF00008101668 fastq.gz 1.3 GB
EGAF00008101669 fastq.gz 1.1 GB
EGAF00008101670 fastq.gz 1.1 GB
EGAF00008101671 fastq.gz 798.1 MB
EGAF00008101672 fastq.gz 825.6 MB
EGAF00008101673 fastq.gz 741.2 MB
EGAF00008101674 fastq.gz 1.0 GB
EGAF00008101675 fastq.gz 739.8 MB
EGAF00008101676 fastq.gz 704.0 MB
EGAF00008101677 fastq.gz 633.2 MB
EGAF00008101678 fastq.gz 1.1 GB
EGAF00008101679 fastq.gz 650.6 MB
EGAF00008101680 fastq.gz 773.7 MB
EGAF00008101681 fastq.gz 952.7 MB
EGAF00008101682 fastq.gz 1.3 GB
EGAF00008101683 fastq.gz 1.2 GB
EGAF00008101684 fastq.gz 1.1 GB
EGAF00008101685 fastq.gz 1.2 GB
EGAF00008101686 fastq.gz 339.3 MB
EGAF00008101687 fastq.gz 1.3 GB
EGAF00008101688 fastq.gz 1.2 GB
EGAF00008101689 fastq.gz 884.5 MB
EGAF00008101690 fastq.gz 1.2 GB
EGAF00008101691 fastq.gz 1.1 GB
EGAF00008101692 fastq.gz 1.2 GB
EGAF00008101693 fastq.gz 1.3 GB
EGAF00008101694 fastq.gz 1.0 GB
EGAF00008101695 fastq.gz 1.2 GB
EGAF00008101696 fastq.gz 1.2 GB
EGAF00008101697 fastq.gz 989.1 MB
EGAF00008101698 fastq.gz 953.5 MB
EGAF00008101699 fastq.gz 1.4 GB
EGAF00008101700 fastq.gz 1.4 GB
EGAF00008101701 fastq.gz 1.6 GB
EGAF00008101702 fastq.gz 1.4 GB
EGAF00008101703 fastq.gz 1.3 GB
EGAF00008101704 fastq.gz 1.6 GB
EGAF00008101705 fastq.gz 1.4 GB
EGAF00008101706 fastq.gz 1.5 GB
EGAF00008101707 fastq.gz 1.3 GB
EGAF00008101708 fastq.gz 968.9 MB
EGAF00008101709 fastq.gz 1.0 GB
EGAF00008101710 fastq.gz 1.1 GB
EGAF00008101711 fastq.gz 743.8 MB
EGAF00008101712 fastq.gz 928.0 MB
EGAF00008101713 fastq.gz 1.1 GB
EGAF00008101714 fastq.gz 967.1 MB
EGAF00008101715 fastq.gz 798.5 MB
EGAF00008101716 fastq.gz 864.9 MB
EGAF00008101717 fastq.gz 1.2 GB
EGAF00008101718 fastq.gz 1.0 GB
EGAF00008101719 fastq.gz 947.1 MB
EGAF00008101720 fastq.gz 993.8 MB
EGAF00008101721 fastq.gz 855.4 MB
EGAF00008101722 fastq.gz 870.7 MB
EGAF00008101723 fastq.gz 1.0 GB
EGAF00008101724 fastq.gz 1.4 GB
EGAF00008101725 fastq.gz 1.6 GB
EGAF00008101726 fastq.gz 942.2 MB
EGAF00008101727 fastq.gz 982.7 MB
EGAF00008101728 fastq.gz 997.8 MB
EGAF00008101729 fastq.gz 1.0 GB
EGAF00008101730 fastq.gz 1.3 GB
EGAF00008101731 fastq.gz 1.3 GB
EGAF00008101732 fastq.gz 1.3 GB
EGAF00008101733 fastq.gz 1.3 GB
EGAF00008101734 fastq.gz 1.2 GB
EGAF00008101735 fastq.gz 1.5 GB
EGAF00008101736 fastq.gz 1.3 GB
EGAF00008101737 fastq.gz 1.4 GB
EGAF00008101738 fastq.gz 1.3 GB
EGAF00008101739 fastq.gz 1.4 GB
EGAF00008101740 fastq.gz 1.3 GB
EGAF00008101741 fastq.gz 1.4 GB
EGAF00008101742 fastq.gz 1.3 GB
EGAF00008101743 fastq.gz 1.3 GB
EGAF00008101744 fastq.gz 1.4 GB
EGAF00008101745 fastq.gz 1.3 GB
EGAF00008101746 fastq.gz 7.0 GB
EGAF00008101747 fastq.gz 7.3 GB
EGAF00008101748 fastq.gz 4.8 GB
EGAF00008101749 fastq.gz 5.0 GB
EGAF00008101750 fastq.gz 3.9 GB
EGAF00008101751 fastq.gz 4.0 GB
EGAF00008101752 fastq.gz 4.5 GB
EGAF00008101753 fastq.gz 4.7 GB
EGAF00008101754 fastq.gz 4.4 GB
EGAF00008101755 fastq.gz 4.5 GB
EGAF00008101756 fastq.gz 4.3 GB
EGAF00008101757 fastq.gz 4.4 GB
EGAF00008101758 fastq.gz 5.2 GB
EGAF00008101759 fastq.gz 5.4 GB
EGAF00008172744 fastq.gz 534.8 MB
348 Files (1.2 TB)