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Colorectal cancer organoid-stroma biobank cohort

In colorectal cancers (CRC) the tumor microenvironment plays a key role for prognosis and therapy efficacy. Patient-derived tumor organoids (PDTOs) show enormous potential for preclinical testing, however, purely epithelial cultures features including the ‘consensus molecular subtypes’ (CMS) are largely eradicated. To better reflect the cell type heterogeneity, we established the CRC organoid-stroma biobank of matched PDTOs and cancer-associated fibroblasts (CAFs) from 30 patients. Whole exome sequencing and transcriptome analysis in various in vitro and in vivo contexts was performed to study the influence of the TME on the CRC phenotype.

Request Access

Data access policy of organoid-stroma biobank

For access to sequencing data deposited to the European Genome-phenome Archive (EGA), application documents should be completed and returned to the Data Access Committee (DAC) of the Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy (email address: data-access@georg-speyer-haus.de). Applications will only be accepted electronically. Any queries regarding access procedures or completion of the forms should be sent to this address. Additional information on the data access procedure can be obtained on the EGA webpage (https://ega-archive.org/). Application requires the completion of the Data Access Agreement (including Appendix I, II and III) for each data set that must be signed by the legal entity with which you are affiliated (signed and stamped, no electronic signature). Additionally, the DAC needs a document providing proof that the applicant is working in a scientific organization (signed and stamped by a legal authority of the organization). In case of collaborative applications each institution has to submit its own application. User institutions located outside the EU/ EEA (European Economic Area) are requested to additionally enter into the Standard Contractual Clauses for the transfer of personal data to third countries. The form must be completed (including Annex A and B) and signed. Technical problems with the EGA download should be reported directly to the EGA Helpdesk. (helpdesk@ega-archive.org)

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001007300 Other
EGAS00001007301 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF00008087774 fastq.gz 454.5 MB Report
EGAF00008087775 fastq.gz 1.6 GB Report
EGAF00008087776 fastq.gz 6.0 GB Report
EGAF00008087777 fastq.gz 6.1 GB Report
EGAF00008087778 fastq.gz 4.6 GB Report
EGAF00008087779 fastq.gz 4.7 GB Report
EGAF00008087780 fastq.gz 4.5 GB Report
EGAF00008087781 fastq.gz 4.6 GB Report
EGAF00008087782 fastq.gz 4.2 GB Report
EGAF00008087783 fastq.gz 4.4 GB Report
EGAF00008087784 fastq.gz 3.6 GB Report
EGAF00008087785 fastq.gz 3.5 GB Report
EGAF00008087786 fastq.gz 5.6 GB Report
EGAF00008087787 fastq.gz 5.6 GB Report
EGAF00008087788 fastq.gz 5.1 GB Report
EGAF00008087789 fastq.gz 5.2 GB Report
EGAF00008087790 fastq.gz 5.1 GB Report
EGAF00008087791 fastq.gz 5.2 GB Report
EGAF00008087792 fastq.gz 4.8 GB Report
EGAF00008087793 fastq.gz 4.9 GB Report
EGAF00008087794 fastq.gz 5.4 GB Report
EGAF00008087795 fastq.gz 5.5 GB Report
EGAF00008087796 fastq.gz 5.6 GB Report
EGAF00008087797 fastq.gz 6.1 GB Report
EGAF00008087798 fastq.gz 4.5 GB Report
EGAF00008087799 fastq.gz 5.0 GB Report
EGAF00008087800 fastq.gz 4.4 GB Report
EGAF00008087801 fastq.gz 4.8 GB Report
EGAF00008087802 fastq.gz 5.1 GB Report
EGAF00008087803 fastq.gz 5.6 GB Report
EGAF00008087804 fastq.gz 4.9 GB Report
EGAF00008087805 fastq.gz 5.4 GB Report
EGAF00008087806 fastq.gz 5.1 GB Report
EGAF00008087807 fastq.gz 5.5 GB Report
EGAF00008087808 fastq.gz 4.9 GB Report
EGAF00008087809 fastq.gz 5.4 GB Report
EGAF00008087810 fastq.gz 4.5 GB Report
EGAF00008087811 fastq.gz 4.9 GB Report
EGAF00008087812 fastq.gz 5.3 GB Report
EGAF00008087813 fastq.gz 5.9 GB Report
EGAF00008087814 fastq.gz 4.7 GB Report
EGAF00008087815 fastq.gz 5.2 GB Report
EGAF00008087816 fastq.gz 5.8 GB Report
EGAF00008087817 fastq.gz 6.4 GB Report
EGAF00008087818 fastq.gz 4.8 GB Report
EGAF00008087819 fastq.gz 5.3 GB Report
EGAF00008087820 fastq.gz 4.3 GB Report
EGAF00008087821 fastq.gz 4.9 GB Report
EGAF00008087822 fastq.gz 4.1 GB Report
EGAF00008087823 fastq.gz 4.6 GB Report
EGAF00008087824 fastq.gz 4.8 GB Report
EGAF00008087825 fastq.gz 5.2 GB Report
EGAF00008087826 fastq.gz 4.9 GB Report
EGAF00008087827 fastq.gz 5.3 GB Report
EGAF00008087828 fastq.gz 5.0 GB Report
EGAF00008087829 fastq.gz 5.4 GB Report
EGAF00008087830 fastq.gz 5.6 GB Report
EGAF00008087831 fastq.gz 6.2 GB Report
EGAF00008087832 fastq.gz 4.9 GB Report
EGAF00008087833 fastq.gz 5.3 GB Report
EGAF00008087834 fastq.gz 5.0 GB Report
EGAF00008087835 fastq.gz 5.3 GB Report
EGAF00008087836 fastq.gz 6.0 GB Report
EGAF00008087837 fastq.gz 6.3 GB Report
EGAF00008087838 fastq.gz 5.9 GB Report
EGAF00008087839 fastq.gz 6.2 GB Report
EGAF00008087840 fastq.gz 5.7 GB Report
EGAF00008087841 fastq.gz 5.9 GB Report
EGAF00008087842 fastq.gz 6.8 GB Report
EGAF00008087843 fastq.gz 7.1 GB Report
EGAF00008087844 fastq.gz 6.1 GB Report
EGAF00008087845 fastq.gz 6.3 GB Report
EGAF00008087846 fastq.gz 4.8 GB Report
EGAF00008087847 fastq.gz 5.0 GB Report
EGAF00008087848 fastq.gz 5.0 GB Report
EGAF00008087849 fastq.gz 5.0 GB Report
EGAF00008087850 fastq.gz 4.8 GB Report
EGAF00008087851 fastq.gz 5.0 GB Report
EGAF00008087852 fastq.gz 5.9 GB Report
EGAF00008087853 fastq.gz 6.5 GB Report
EGAF00008087854 fastq.gz 6.8 GB Report
EGAF00008087855 fastq.gz 7.6 GB Report
EGAF00008087856 fastq.gz 5.8 GB Report
EGAF00008087857 fastq.gz 6.3 GB Report
EGAF00008087858 fastq.gz 5.0 GB Report
EGAF00008087859 fastq.gz 5.4 GB Report
EGAF00008087860 fastq.gz 6.4 GB Report
EGAF00008087861 fastq.gz 6.9 GB Report
EGAF00008087862 fastq.gz 6.8 GB Report
EGAF00008087863 fastq.gz 7.4 GB Report
EGAF00008087864 fastq.gz 4.6 GB Report
EGAF00008087865 fastq.gz 5.1 GB Report
EGAF00008087866 fastq.gz 5.2 GB Report
EGAF00008087867 fastq.gz 5.7 GB Report
EGAF00008087868 fastq.gz 4.8 GB Report
EGAF00008087869 fastq.gz 5.3 GB Report
EGAF00008087870 fastq.gz 5.1 GB Report
EGAF00008087871 fastq.gz 5.6 GB Report
EGAF00008087872 fastq.gz 6.2 GB Report
EGAF00008087873 fastq.gz 6.8 GB Report
EGAF00008087874 fastq.gz 6.6 GB Report
EGAF00008087875 fastq.gz 7.3 GB Report
EGAF00008087876 fastq.gz 6.9 GB Report
EGAF00008087877 fastq.gz 7.5 GB Report
EGAF00008087878 fastq.gz 5.8 GB Report
EGAF00008087879 fastq.gz 6.3 GB Report
EGAF00008087880 fastq.gz 6.4 GB Report
EGAF00008087881 fastq.gz 7.0 GB Report
EGAF00008087882 fastq.gz 7.4 GB Report
EGAF00008087883 fastq.gz 8.3 GB Report
EGAF00008087884 fastq.gz 5.3 GB Report
EGAF00008087885 fastq.gz 5.9 GB Report
EGAF00008087886 fastq.gz 5.0 GB Report
EGAF00008087887 fastq.gz 5.4 GB Report
EGAF00008087888 fastq.gz 5.2 GB Report
EGAF00008087889 fastq.gz 5.6 GB Report
EGAF00008087890 fastq.gz 4.7 GB Report
EGAF00008087891 fastq.gz 4.9 GB Report
EGAF00008087892 fastq.gz 4.8 GB Report
EGAF00008087893 fastq.gz 5.1 GB Report
EGAF00008087894 fastq.gz 4.5 GB Report
EGAF00008087895 fastq.gz 4.7 GB Report
EGAF00008087896 fastq.gz 4.0 GB Report
EGAF00008087897 fastq.gz 4.2 GB Report
EGAF00008087898 fastq.gz 4.7 GB Report
EGAF00008087899 fastq.gz 4.9 GB Report
EGAF00008087900 fastq.gz 4.8 GB Report
EGAF00008087901 fastq.gz 5.0 GB Report
EGAF00008087902 fastq.gz 4.9 GB Report
EGAF00008087903 fastq.gz 5.5 GB Report
EGAF00008087904 fastq.gz 4.7 GB Report
EGAF00008087905 fastq.gz 5.1 GB Report
EGAF00008087906 fastq.gz 5.6 GB Report
EGAF00008087907 fastq.gz 6.1 GB Report
EGAF00008087908 fastq.gz 4.3 GB Report
EGAF00008087909 fastq.gz 4.8 GB Report
EGAF00008087910 fastq.gz 4.9 GB Report
EGAF00008087911 fastq.gz 5.4 GB Report
EGAF00008087912 fastq.gz 4.6 GB Report
EGAF00008087913 fastq.gz 5.1 GB Report
EGAF00008087914 fastq.gz 4.2 GB Report
EGAF00008087915 fastq.gz 4.7 GB Report
EGAF00008087916 fastq.gz 5.2 GB Report
EGAF00008087917 fastq.gz 5.7 GB Report
EGAF00008087918 fastq.gz 5.0 GB Report
EGAF00008087919 fastq.gz 5.4 GB Report
EGAF00008087920 fastq.gz 4.8 GB Report
EGAF00008087921 fastq.gz 5.3 GB Report
EGAF00008087922 fastq.gz 4.9 GB Report
EGAF00008087923 fastq.gz 5.2 GB Report
EGAF00008087924 fastq.gz 5.8 GB Report
EGAF00008087925 fastq.gz 6.3 GB Report
EGAF00008087926 fastq.gz 5.1 GB Report
EGAF00008087927 fastq.gz 5.5 GB Report
EGAF00008087928 fastq.gz 4.9 GB Report
EGAF00008087929 fastq.gz 5.4 GB Report
EGAF00008087930 fastq.gz 4.5 GB Report
EGAF00008087931 fastq.gz 5.0 GB Report
EGAF00008087932 fastq.gz 5.5 GB Report
EGAF00008087933 fastq.gz 6.1 GB Report
EGAF00008087934 fastq.gz 4.6 GB Report
EGAF00008087935 fastq.gz 4.9 GB Report
EGAF00008087936 fastq.gz 5.1 GB Report
EGAF00008087937 fastq.gz 5.6 GB Report
EGAF00008087938 fastq.gz 5.1 GB Report
EGAF00008087939 fastq.gz 5.6 GB Report
EGAF00008087940 fastq.gz 5.5 GB Report
EGAF00008087941 fastq.gz 5.7 GB Report
EGAF00008101581 fastq.gz 1.1 GB Report
EGAF00008101582 fastq.gz 1.0 GB Report
EGAF00008101583 fastq.gz 1.0 GB Report
EGAF00008101584 fastq.gz 1.5 GB Report
EGAF00008101585 fastq.gz 1.0 GB Report
EGAF00008101586 fastq.gz 1.3 GB Report
EGAF00008101587 fastq.gz 869.7 MB Report
EGAF00008101588 fastq.gz 918.3 MB Report
EGAF00008101589 fastq.gz 1.1 GB Report
EGAF00008101590 fastq.gz 1.1 GB Report
EGAF00008101591 fastq.gz 1.2 GB Report
EGAF00008101592 fastq.gz 1.7 GB Report
EGAF00008101593 fastq.gz 1.3 GB Report
EGAF00008101594 fastq.gz 1.1 GB Report
EGAF00008101595 fastq.gz 1.0 GB Report
EGAF00008101596 fastq.gz 1.1 GB Report
EGAF00008101597 fastq.gz 1.1 GB Report
EGAF00008101598 fastq.gz 1.2 GB Report
EGAF00008101599 fastq.gz 1.4 GB Report
EGAF00008101600 fastq.gz 1.3 GB Report
EGAF00008101601 fastq.gz 1.2 GB Report
EGAF00008101602 fastq.gz 964.8 MB Report
EGAF00008101603 fastq.gz 997.4 MB Report
EGAF00008101604 fastq.gz 1.4 GB Report
EGAF00008101605 fastq.gz 1.4 GB Report
EGAF00008101606 fastq.gz 1.3 GB Report
EGAF00008101607 fastq.gz 1.3 GB Report
EGAF00008101608 fastq.gz 1.0 GB Report
EGAF00008101609 fastq.gz 1.3 GB Report
EGAF00008101610 fastq.gz 1.4 GB Report
EGAF00008101611 fastq.gz 1.5 GB Report
EGAF00008101612 fastq.gz 1.4 GB Report
EGAF00008101613 fastq.gz 1.0 GB Report
EGAF00008101614 fastq.gz 861.4 MB Report
EGAF00008101615 fastq.gz 1.2 GB Report
EGAF00008101616 fastq.gz 941.9 MB Report
EGAF00008101617 fastq.gz 1.7 GB Report
EGAF00008101618 fastq.gz 1.1 GB Report
EGAF00008101619 fastq.gz 1.8 GB Report
EGAF00008101620 fastq.gz 1.7 GB Report
EGAF00008101621 fastq.gz 311.7 MB Report
EGAF00008101622 fastq.gz 1.5 GB Report
EGAF00008101623 fastq.gz 791.1 MB Report
EGAF00008101624 fastq.gz 2.4 GB Report
EGAF00008101625 fastq.gz 1.7 GB Report
EGAF00008101626 fastq.gz 1.3 GB Report
EGAF00008101627 fastq.gz 1.3 GB Report
EGAF00008101628 fastq.gz 1.5 GB Report
EGAF00008101629 fastq.gz 1.4 GB Report
EGAF00008101630 fastq.gz 1.6 GB Report
EGAF00008101631 fastq.gz 1.3 GB Report
EGAF00008101632 fastq.gz 1.8 GB Report
EGAF00008101633 fastq.gz 1.4 GB Report
EGAF00008101634 fastq.gz 1.4 GB Report
EGAF00008101635 fastq.gz 1.4 GB Report
EGAF00008101636 fastq.gz 1.4 GB Report
EGAF00008101637 fastq.gz 1.2 GB Report
EGAF00008101638 fastq.gz 1.1 GB Report
EGAF00008101639 fastq.gz 1.1 GB Report
EGAF00008101640 fastq.gz 1.0 GB Report
EGAF00008101641 fastq.gz 763.9 MB Report
EGAF00008101642 fastq.gz 1.2 GB Report
EGAF00008101643 fastq.gz 853.4 MB Report
EGAF00008101644 fastq.gz 767.3 MB Report
EGAF00008101645 fastq.gz 1.7 GB Report
EGAF00008101646 fastq.gz 1.5 GB Report
EGAF00008101647 fastq.gz 1.2 GB Report
EGAF00008101648 fastq.gz 1.1 GB Report
EGAF00008101649 fastq.gz 1.0 GB Report
EGAF00008101650 fastq.gz 1.1 GB Report
EGAF00008101651 fastq.gz 707.0 MB Report
EGAF00008101652 fastq.gz 665.7 MB Report
EGAF00008101653 fastq.gz 599.9 MB Report
EGAF00008101654 fastq.gz 872.5 MB Report
EGAF00008101655 fastq.gz 716.8 MB Report
EGAF00008101656 fastq.gz 845.6 MB Report
EGAF00008101657 fastq.gz 1.1 GB Report
EGAF00008101658 fastq.gz 1.2 GB Report
EGAF00008101659 fastq.gz 1.1 GB Report
EGAF00008101660 fastq.gz 1.2 GB Report
EGAF00008101661 fastq.gz 1.3 GB Report
EGAF00008101662 fastq.gz 1.3 GB Report
EGAF00008101663 fastq.gz 1.1 GB Report
EGAF00008101664 fastq.gz 1.1 GB Report
EGAF00008101665 fastq.gz 1.0 GB Report
EGAF00008101666 fastq.gz 1.0 GB Report
EGAF00008101667 fastq.gz 1.1 GB Report
EGAF00008101668 fastq.gz 1.3 GB Report
EGAF00008101669 fastq.gz 1.1 GB Report
EGAF00008101670 fastq.gz 1.1 GB Report
EGAF00008101671 fastq.gz 798.1 MB Report
EGAF00008101672 fastq.gz 825.6 MB Report
EGAF00008101673 fastq.gz 741.2 MB Report
EGAF00008101674 fastq.gz 1.0 GB Report
EGAF00008101675 fastq.gz 739.8 MB Report
EGAF00008101676 fastq.gz 704.0 MB Report
EGAF00008101677 fastq.gz 633.2 MB Report
EGAF00008101678 fastq.gz 1.1 GB Report
EGAF00008101679 fastq.gz 650.6 MB Report
EGAF00008101680 fastq.gz 773.7 MB Report
EGAF00008101681 fastq.gz 952.7 MB Report
EGAF00008101682 fastq.gz 1.3 GB Report
EGAF00008101683 fastq.gz 1.2 GB Report
EGAF00008101684 fastq.gz 1.1 GB Report
EGAF00008101685 fastq.gz 1.2 GB Report
EGAF00008101686 fastq.gz 339.3 MB Report
EGAF00008101687 fastq.gz 1.3 GB Report
EGAF00008101688 fastq.gz 1.2 GB Report
EGAF00008101689 fastq.gz 884.5 MB Report
EGAF00008101690 fastq.gz 1.2 GB Report
EGAF00008101691 fastq.gz 1.1 GB Report
EGAF00008101692 fastq.gz 1.2 GB Report
EGAF00008101693 fastq.gz 1.3 GB Report
EGAF00008101694 fastq.gz 1.0 GB Report
EGAF00008101695 fastq.gz 1.2 GB Report
EGAF00008101696 fastq.gz 1.2 GB Report
EGAF00008101697 fastq.gz 989.1 MB Report
EGAF00008101698 fastq.gz 953.5 MB Report
EGAF00008101699 fastq.gz 1.4 GB Report
EGAF00008101700 fastq.gz 1.4 GB Report
EGAF00008101701 fastq.gz 1.6 GB Report
EGAF00008101702 fastq.gz 1.4 GB Report
EGAF00008101703 fastq.gz 1.3 GB Report
EGAF00008101704 fastq.gz 1.6 GB Report
EGAF00008101705 fastq.gz 1.4 GB Report
EGAF00008101706 fastq.gz 1.5 GB Report
EGAF00008101707 fastq.gz 1.3 GB Report
EGAF00008101708 fastq.gz 968.9 MB Report
EGAF00008101709 fastq.gz 1.0 GB Report
EGAF00008101710 fastq.gz 1.1 GB Report
EGAF00008101711 fastq.gz 743.8 MB Report
EGAF00008101712 fastq.gz 928.0 MB Report
EGAF00008101713 fastq.gz 1.1 GB Report
EGAF00008101714 fastq.gz 967.1 MB Report
EGAF00008101715 fastq.gz 798.5 MB Report
EGAF00008101716 fastq.gz 864.9 MB Report
EGAF00008101717 fastq.gz 1.2 GB Report
EGAF00008101718 fastq.gz 1.0 GB Report
EGAF00008101719 fastq.gz 947.1 MB Report
EGAF00008101720 fastq.gz 993.8 MB Report
EGAF00008101721 fastq.gz 855.4 MB Report
EGAF00008101722 fastq.gz 870.7 MB Report
EGAF00008101723 fastq.gz 1.0 GB Report
EGAF00008101724 fastq.gz 1.4 GB Report
EGAF00008101725 fastq.gz 1.6 GB Report
EGAF00008101726 fastq.gz 942.2 MB Report
EGAF00008101727 fastq.gz 982.7 MB Report
EGAF00008101728 fastq.gz 997.8 MB Report
EGAF00008101729 fastq.gz 1.0 GB Report
EGAF00008101730 fastq.gz 1.3 GB Report
EGAF00008101731 fastq.gz 1.3 GB Report
EGAF00008101732 fastq.gz 1.3 GB Report
EGAF00008101733 fastq.gz 1.3 GB Report
EGAF00008101734 fastq.gz 1.2 GB Report
EGAF00008101735 fastq.gz 1.5 GB Report
EGAF00008101736 fastq.gz 1.3 GB Report
EGAF00008101737 fastq.gz 1.4 GB Report
EGAF00008101738 fastq.gz 1.3 GB Report
EGAF00008101739 fastq.gz 1.4 GB Report
EGAF00008101740 fastq.gz 1.3 GB Report
EGAF00008101741 fastq.gz 1.4 GB Report
EGAF00008101742 fastq.gz 1.3 GB Report
EGAF00008101743 fastq.gz 1.3 GB Report
EGAF00008101744 fastq.gz 1.4 GB Report
EGAF00008101745 fastq.gz 1.3 GB Report
EGAF00008101746 fastq.gz 7.0 GB Report
EGAF00008101747 fastq.gz 7.3 GB Report
EGAF00008101748 fastq.gz 4.8 GB Report
EGAF00008101749 fastq.gz 5.0 GB Report
EGAF00008101750 fastq.gz 3.9 GB Report
EGAF00008101751 fastq.gz 4.0 GB Report
EGAF00008101752 fastq.gz 4.5 GB Report
EGAF00008101753 fastq.gz 4.7 GB Report
EGAF00008101754 fastq.gz 4.4 GB Report
EGAF00008101755 fastq.gz 4.5 GB Report
EGAF00008101756 fastq.gz 4.3 GB Report
EGAF00008101757 fastq.gz 4.4 GB Report
EGAF00008101758 fastq.gz 5.2 GB Report
EGAF00008101759 fastq.gz 5.4 GB Report
EGAF00008172744 fastq.gz 534.8 MB Report
348 Files (1.2 TB)