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cfRRBS methylation profiling of cfDNA from cerebrospinal fluid from pediatric CNS tumor patients

In this study, we explore the potential of classifying pediatric brain tumors based on methylation profiling of the cell-free DNA in cerebrospinal fluid (CSF). For this proof-of-concept study, we collected 20 cerebrospinal fluid samples of pediatric brain cancer patients via a ventricular drain placed for reasons of increased intracranial pressure. For 11 patients in this study we collected matched tumor DNA. This cohort contains fastQ files of cfRRBS data of these samples.

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Applicability This policy applies to the access to and transfer of VIB research datasets that contain non-anonymous Personal Data which are subject to the provisions of the General Data Protection Regulation (EU) 2016/679. Access/transfer conditions - The access/transfer is subject to approval by the VIB Data Access Committee. - The proposed research purpose should not be incompatible with the primary research purpose for which the data were originally generated. - The Recipient shall have in place adequate safeguards for the protection of Personal Data. - Access is subject to a Data Transfer/Access Agreement which will be managed by VIB Innovation & Business. - The Data Transfer/Access will be limited to the Data that are necessary for the proposed research. Access/transfer procedure - Requests to access or obtain non-anonymous datasets should be submitted within the EGA portal, which will then generate a notification to the responsible corresponding author that has uploaded the dataset into the repository, and with a copy to dac@vib.be. - VIB will send a request form to the applicant to complete. - The completed form should amongst other request should contain the following information: o Name, affiliation (legal entity) and contact information of the requesting recipient party. o Reference to the specific dataset(s) for which access or transfer is requested. o Description of the research purpose for which the data will be used. - The VIB Data Access Committee takes decisions to approve access/transfer within 14 days upon receipt of the completed request form. - Data access will be given / Data will be transferred after completion of the Data Transfer/Access Agreement.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000377 Epigenetics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF50000125191 fastq.gz 799.7 MB
EGAF50000125192 fastq.gz 779.6 MB
EGAF50000125193 fastq.gz 683.0 MB
EGAF50000125194 fastq.gz 700.4 MB
EGAF50000125195 fastq.gz 597.8 MB
EGAF50000125196 fastq.gz 614.1 MB
EGAF50000125197 fastq.gz 568.2 MB
EGAF50000125198 fastq.gz 584.2 MB
EGAF50000125199 fastq.gz 588.8 MB
EGAF50000125200 fastq.gz 588.4 MB
EGAF50000125201 fastq.gz 615.4 MB
EGAF50000125202 fastq.gz 598.6 MB
EGAF50000125203 fastq.gz 765.7 MB
EGAF50000125204 fastq.gz 824.2 MB
EGAF50000125205 fastq.gz 361.2 MB
EGAF50000125206 fastq.gz 394.5 MB
EGAF50000125207 fastq.gz 559.0 MB
EGAF50000125208 fastq.gz 601.6 MB
EGAF50000125209 fastq.gz 527.8 MB
EGAF50000125210 fastq.gz 567.2 MB
EGAF50000125211 fastq.gz 739.3 MB
EGAF50000125212 fastq.gz 771.3 MB
EGAF50000125213 fastq.gz 663.3 MB
EGAF50000125214 fastq.gz 678.8 MB
EGAF50000125215 fastq.gz 582.5 MB
EGAF50000125216 fastq.gz 588.6 MB
EGAF50000125217 fastq.gz 277.8 MB
EGAF50000125218 fastq.gz 252.3 MB
EGAF50000125219 fastq.gz 790.7 MB
EGAF50000125220 fastq.gz 858.3 MB
EGAF50000125221 fastq.gz 604.7 MB
EGAF50000125222 fastq.gz 655.8 MB
EGAF50000125223 fastq.gz 836.2 MB
EGAF50000125224 fastq.gz 766.9 MB
EGAF50000125225 fastq.gz 666.8 MB
EGAF50000125226 fastq.gz 695.3 MB
EGAF50000125227 fastq.gz 646.0 MB
EGAF50000125228 fastq.gz 683.2 MB
EGAF50000125229 fastq.gz 643.1 MB
EGAF50000125230 fastq.gz 673.0 MB
EGAF50000125231 fastq.gz 601.5 MB
EGAF50000125232 fastq.gz 627.6 MB
EGAF50000125233 fastq.gz 880.4 MB
EGAF50000125234 fastq.gz 919.8 MB
EGAF50000125235 fastq.gz 177.6 MB
EGAF50000125236 fastq.gz 183.4 MB
EGAF50000125237 fastq.gz 373.1 MB
EGAF50000125238 fastq.gz 409.4 MB
EGAF50000125239 fastq.gz 530.0 MB
EGAF50000125240 fastq.gz 577.0 MB
EGAF50000125241 fastq.gz 470.5 MB
EGAF50000125242 fastq.gz 506.6 MB
EGAF50000125243 fastq.gz 421.7 MB
EGAF50000125244 fastq.gz 451.6 MB
EGAF50000125245 fastq.gz 578.0 MB
EGAF50000125246 fastq.gz 622.6 MB
EGAF50000125247 fastq.gz 492.7 MB
EGAF50000125248 fastq.gz 515.3 MB
EGAF50000125249 fastq.gz 497.6 MB
EGAF50000125250 fastq.gz 520.0 MB
EGAF50000125251 fastq.gz 530.4 MB
EGAF50000125252 fastq.gz 556.4 MB
EGAF50000125253 fastq.gz 567.7 MB
EGAF50000125254 fastq.gz 596.4 MB
EGAF50000125255 fastq.gz 533.3 MB
EGAF50000125256 fastq.gz 558.1 MB
EGAF50000125257 fastq.gz 262.1 MB
EGAF50000125258 fastq.gz 251.9 MB
EGAF50000125259 fastq.gz 570.6 MB
EGAF50000125260 fastq.gz 585.1 MB
EGAF50000125261 fastq.gz 829.2 MB
EGAF50000125262 fastq.gz 775.5 MB
EGAF50000125263 fastq.gz 604.1 MB
EGAF50000125264 fastq.gz 642.8 MB
EGAF50000125265 fastq.gz 725.8 MB
EGAF50000125266 fastq.gz 750.8 MB
EGAF50000125267 fastq.gz 521.2 MB
EGAF50000125268 fastq.gz 544.9 MB
EGAF50000125269 fastq.gz 541.3 MB
EGAF50000125270 fastq.gz 567.0 MB
EGAF50000125271 fastq.gz 656.5 MB
EGAF50000125272 fastq.gz 679.0 MB
EGAF50000125273 fastq.gz 487.4 MB
EGAF50000125274 fastq.gz 486.6 MB
EGAF50000125275 fastq.gz 673.6 MB
EGAF50000125276 fastq.gz 720.0 MB
86 Files (51.0 GB)