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A comprehensive DNA methylation landscape of human and mouse cell lines derived from hematological malignancies

The dataset from Infinium Human MethylationEPIC v1.0 (IDAT files) includes 91 primary samples from patients with B-cell acute lymphoblastic leukemia (B-ALL) (n=34) and T-cell acute lymphoblastic leukemia (T-ALL) (n=57). This dataset was used in the article "A Comprehensive DNA Methylation Landscape of Human and Mouse Cell Lines Derived from Hematological Malignancies" to validate differentially methylated CpG sites, which were utilized to classify hematologic malignancies.

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Data Access Policy for single-cell proteogenomics of MDS upon AZA treatment data.

1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify Manel Esteller within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify Manel Esteller prior to any significant changes to the protocol for the Project. 14. The User Institution will notify Manel Esteller as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. Manel Esteller may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. As an example, this may include specific provisions relating to the Data required by Data Producers other than Manel Esteller. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of Catalonia and Spain and shall be subject to the exclusive jurisdiction of the Catalan and Spanish courts.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000627 Epigenetics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF50000205829 idat 13.7 MB
EGAF50000205830 idat 13.7 MB
EGAF50000205831 idat 13.7 MB
EGAF50000205832 idat 13.7 MB
EGAF50000205833 idat 13.7 MB
EGAF50000205834 idat 13.7 MB
EGAF50000205835 idat 13.7 MB
EGAF50000205836 idat 13.7 MB
EGAF50000205837 idat 13.7 MB
EGAF50000205838 idat 13.7 MB
EGAF50000205839 idat 13.7 MB
EGAF50000205840 idat 13.7 MB
EGAF50000205841 idat 13.7 MB
EGAF50000205842 idat 13.7 MB
EGAF50000205843 idat 13.7 MB
EGAF50000205844 idat 13.7 MB
EGAF50000205845 idat 13.7 MB
EGAF50000205846 idat 13.7 MB
EGAF50000205847 idat 13.7 MB
EGAF50000205848 idat 13.7 MB
EGAF50000205849 idat 13.7 MB
EGAF50000205850 idat 13.7 MB
EGAF50000205851 idat 13.7 MB
EGAF50000205852 idat 13.7 MB
EGAF50000205853 idat 13.7 MB
EGAF50000205854 idat 13.7 MB
EGAF50000205855 idat 13.7 MB
EGAF50000205856 idat 13.7 MB
EGAF50000205857 idat 13.7 MB
EGAF50000205858 idat 13.7 MB
EGAF50000205859 idat 13.7 MB
EGAF50000205860 idat 13.7 MB
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EGAF50000205862 idat 13.7 MB
EGAF50000205863 idat 13.7 MB
EGAF50000205864 idat 13.7 MB
EGAF50000205865 idat 13.7 MB
EGAF50000205866 idat 13.7 MB
EGAF50000205867 idat 13.7 MB
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EGAF50000205869 idat 13.7 MB
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EGAF50000205871 idat 13.7 MB
EGAF50000205872 idat 13.7 MB
EGAF50000205873 idat 13.7 MB
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EGAF50000205875 idat 13.7 MB
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EGAF50000205879 idat 13.7 MB
EGAF50000205880 idat 13.7 MB
EGAF50000205881 idat 13.7 MB
EGAF50000205882 idat 13.7 MB
EGAF50000205883 idat 13.7 MB
EGAF50000205884 idat 13.7 MB
EGAF50000205885 idat 13.7 MB
EGAF50000205886 idat 13.7 MB
EGAF50000205887 idat 13.7 MB
EGAF50000205888 idat 13.7 MB
EGAF50000205889 idat 13.7 MB
EGAF50000205890 idat 13.7 MB
EGAF50000205891 idat 13.7 MB
EGAF50000205892 idat 13.7 MB
EGAF50000205893 idat 13.7 MB
EGAF50000205894 idat 13.7 MB
EGAF50000205895 idat 13.7 MB
EGAF50000205896 idat 13.7 MB
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EGAF50000205899 idat 13.7 MB
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EGAF50000205903 idat 13.7 MB
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EGAF50000205905 idat 13.7 MB
EGAF50000205906 idat 13.7 MB
EGAF50000205907 idat 13.7 MB
EGAF50000205908 idat 13.7 MB
EGAF50000205909 idat 13.7 MB
EGAF50000205910 idat 13.7 MB
EGAF50000205911 idat 13.7 MB
EGAF50000205912 idat 13.7 MB
EGAF50000205913 idat 13.7 MB
EGAF50000205914 idat 13.7 MB
EGAF50000205915 idat 13.7 MB
EGAF50000205916 idat 13.7 MB
EGAF50000205917 idat 13.7 MB
EGAF50000205918 idat 13.7 MB
EGAF50000205919 idat 13.7 MB
EGAF50000205920 idat 13.7 MB
EGAF50000205921 idat 13.7 MB
EGAF50000205922 idat 13.7 MB
EGAF50000205923 idat 13.7 MB
EGAF50000205924 idat 13.7 MB
EGAF50000205925 idat 13.7 MB
EGAF50000205926 idat 13.7 MB
EGAF50000205927 idat 13.7 MB
EGAF50000205928 idat 13.7 MB
EGAF50000205929 idat 13.7 MB
EGAF50000205930 idat 13.7 MB
EGAF50000205931 idat 13.7 MB
EGAF50000205932 idat 13.7 MB
EGAF50000205933 idat 13.7 MB
EGAF50000205934 idat 13.7 MB
EGAF50000205935 idat 13.7 MB
EGAF50000205936 idat 13.7 MB
EGAF50000205937 idat 13.7 MB
EGAF50000205938 idat 13.7 MB
EGAF50000205939 idat 13.7 MB
EGAF50000205940 idat 13.7 MB
EGAF50000205941 idat 13.7 MB
EGAF50000205942 idat 13.7 MB
EGAF50000205943 idat 13.7 MB
EGAF50000205944 idat 13.7 MB
EGAF50000205945 idat 13.7 MB
EGAF50000205946 idat 13.7 MB
EGAF50000205947 idat 13.7 MB
EGAF50000205948 idat 13.7 MB
EGAF50000205949 idat 13.7 MB
EGAF50000205950 idat 13.7 MB
EGAF50000205951 idat 13.7 MB
EGAF50000205952 idat 13.7 MB
EGAF50000205953 idat 13.7 MB
EGAF50000205954 idat 13.7 MB
EGAF50000205955 idat 13.7 MB
EGAF50000205956 idat 13.7 MB
EGAF50000205957 idat 13.7 MB
EGAF50000205958 idat 13.7 MB
EGAF50000205959 idat 13.7 MB
EGAF50000205960 idat 13.7 MB
EGAF50000205961 idat 13.7 MB
EGAF50000205962 idat 13.7 MB
EGAF50000205963 idat 13.7 MB
EGAF50000205964 idat 13.7 MB
EGAF50000205965 idat 13.7 MB
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EGAF50000205967 idat 13.7 MB
EGAF50000205968 idat 13.7 MB
EGAF50000205969 idat 13.7 MB
EGAF50000205970 idat 13.7 MB
EGAF50000205971 idat 13.7 MB
EGAF50000205972 idat 13.7 MB
EGAF50000205973 idat 13.7 MB
EGAF50000205974 idat 13.7 MB
EGAF50000205975 idat 13.7 MB
EGAF50000205976 idat 13.7 MB
EGAF50000205977 idat 13.7 MB
EGAF50000205978 idat 13.7 MB
EGAF50000205979 idat 13.7 MB
EGAF50000205980 idat 13.7 MB
EGAF50000205981 idat 13.7 MB
EGAF50000205982 idat 13.7 MB
EGAF50000205983 idat 13.7 MB
EGAF50000205984 idat 13.7 MB
EGAF50000205985 idat 13.7 MB
EGAF50000205986 idat 13.7 MB
EGAF50000205987 idat 13.7 MB
EGAF50000205988 idat 13.7 MB
EGAF50000205989 idat 13.7 MB
EGAF50000205990 idat 13.7 MB
EGAF50000205991 idat 13.7 MB
EGAF50000205992 idat 13.7 MB
EGAF50000205993 idat 13.7 MB
EGAF50000205994 idat 13.7 MB
EGAF50000205995 idat 13.7 MB
EGAF50000205996 idat 13.7 MB
EGAF50000205997 idat 13.7 MB
EGAF50000205998 idat 13.7 MB
EGAF50000205999 idat 13.7 MB
EGAF50000206000 idat 13.7 MB
EGAF50000206001 idat 13.7 MB
EGAF50000206002 idat 13.7 MB
EGAF50000206003 idat 13.7 MB
EGAF50000206004 idat 13.7 MB
EGAF50000206005 idat 13.7 MB
EGAF50000206006 idat 13.7 MB
EGAF50000206007 idat 13.7 MB
EGAF50000206008 idat 13.7 MB
EGAF50000206009 idat 13.7 MB
EGAF50000206010 idat 13.7 MB
182 Files (2.5 GB)