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WGS data of 100 Breast Cancer patients from SV Based ctDNA Detection study

Whole Genome Sequencing data of 100 Breast Cancer patients from "Ultrasensitive Detection and Monitoring of Circulating Tumor DNA using Structural Variants in Early-Stage Breast Cancer" study.

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DATA ACCESS AGREEMENT

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorised Personnel: The individuals at the User Institution to whom the Data Access Committee (DAC) grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: The Principal Investigator and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. University Health Network: The University Health Network (UHN) is the largest clinical and research hospital in Canada. UHN is affiliated with the University of Toronto and is a member of the Toronto Academic Health Science Network. 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify the DAC within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify the DAC prior to any significant changes to the protocol for the Project. 14. The User Institution will notify the DAC as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. The DAC may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of the province of Ontario and PHIPA.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000799 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF50000289305 fastq.gz 29.5 GB
EGAF50000289306 fastq.gz 28.4 GB
EGAF50000289307 fastq.gz 29.3 GB
EGAF50000289308 fastq.gz 31.2 GB
EGAF50000289309 fastq.gz 36.1 GB
EGAF50000289310 fastq.gz 30.9 GB
EGAF50000289311 fastq.gz 43.6 GB
EGAF50000289312 fastq.gz 44.8 GB
EGAF50000289313 fastq.gz 46.6 GB
EGAF50000289314 fastq.gz 32.2 GB
EGAF50000289315 fastq.gz 33.2 GB
EGAF50000289316 fastq.gz 31.2 GB
EGAF50000289317 fastq.gz 34.4 GB
EGAF50000289318 fastq.gz 35.5 GB
EGAF50000289319 fastq.gz 42.4 GB
EGAF50000289320 fastq.gz 21.9 GB
EGAF50000289321 fastq.gz 22.7 GB
EGAF50000289322 fastq.gz 82.0 GB
EGAF50000289323 fastq.gz 86.9 GB
EGAF50000289324 fastq.gz 48.1 GB
EGAF50000289325 fastq.gz 54.9 GB
EGAF50000289326 fastq.gz 57.0 GB
EGAF50000289327 fastq.gz 61.1 GB
EGAF50000289328 fastq.gz 28.1 GB
EGAF50000289329 fastq.gz 39.0 GB
EGAF50000289330 fastq.gz 26.9 GB
EGAF50000289331 fastq.gz 49.6 GB
EGAF50000289332 fastq.gz 28.5 GB
EGAF50000289333 fastq.gz 29.9 GB
EGAF50000289334 fastq.gz 39.9 GB
EGAF50000289335 fastq.gz 30.3 GB
EGAF50000289336 fastq.gz 31.4 GB
EGAF50000289337 fastq.gz 52.3 GB
EGAF50000289338 fastq.gz 29.8 GB
EGAF50000289339 fastq.gz 34.4 GB
EGAF50000289340 fastq.gz 37.7 GB
EGAF50000289341 fastq.gz 39.7 GB
EGAF50000289342 fastq.gz 40.4 GB
EGAF50000289343 fastq.gz 32.2 GB
EGAF50000289344 fastq.gz 33.5 GB
EGAF50000289345 fastq.gz 40.4 GB
EGAF50000289346 fastq.gz 34.9 GB
EGAF50000289347 fastq.gz 37.0 GB
EGAF50000289348 fastq.gz 40.7 GB
EGAF50000289349 fastq.gz 48.8 GB
EGAF50000289350 fastq.gz 41.0 GB
EGAF50000289351 fastq.gz 37.1 GB
EGAF50000289352 fastq.gz 36.6 GB
EGAF50000289353 fastq.gz 27.6 GB
EGAF50000289354 fastq.gz 75.2 GB
EGAF50000289355 fastq.gz 34.0 GB
EGAF50000289356 fastq.gz 33.4 GB
EGAF50000289357 fastq.gz 31.4 GB
EGAF50000289358 fastq.gz 40.3 GB
EGAF50000289359 fastq.gz 37.1 GB
EGAF50000289360 fastq.gz 31.6 GB
EGAF50000289361 fastq.gz 37.4 GB
EGAF50000289362 fastq.gz 39.5 GB
EGAF50000289363 fastq.gz 38.6 GB
EGAF50000289364 fastq.gz 33.4 GB
EGAF50000289365 fastq.gz 38.4 GB
EGAF50000289366 fastq.gz 58.4 GB
EGAF50000289367 fastq.gz 29.0 GB
EGAF50000289368 fastq.gz 40.6 GB
EGAF50000289369 fastq.gz 51.7 GB
EGAF50000289370 fastq.gz 27.8 GB
EGAF50000289371 fastq.gz 31.5 GB
EGAF50000289372 fastq.gz 25.6 GB
EGAF50000289373 fastq.gz 26.7 GB
EGAF50000289374 fastq.gz 35.9 GB
EGAF50000289375 fastq.gz 34.3 GB
EGAF50000289376 fastq.gz 36.4 GB
EGAF50000289377 fastq.gz 40.9 GB
EGAF50000289378 fastq.gz 24.1 GB
EGAF50000289379 fastq.gz 33.5 GB
EGAF50000289380 fastq.gz 34.6 GB
EGAF50000289381 fastq.gz 39.8 GB
EGAF50000289382 fastq.gz 37.4 GB
EGAF50000289383 fastq.gz 38.5 GB
EGAF50000289384 fastq.gz 26.4 GB
EGAF50000289385 fastq.gz 27.8 GB
EGAF50000289386 fastq.gz 29.0 GB
EGAF50000289387 fastq.gz 32.4 GB
EGAF50000289388 fastq.gz 33.6 GB
EGAF50000289389 fastq.gz 53.0 GB
EGAF50000289390 fastq.gz 52.5 GB
EGAF50000289391 fastq.gz 55.3 GB
EGAF50000289392 fastq.gz 30.0 GB
EGAF50000289393 fastq.gz 36.1 GB
EGAF50000289394 fastq.gz 30.7 GB
EGAF50000289395 fastq.gz 34.5 GB
EGAF50000289396 fastq.gz 46.0 GB
EGAF50000289397 fastq.gz 25.6 GB
EGAF50000289398 fastq.gz 27.0 GB
EGAF50000289399 fastq.gz 34.5 GB
EGAF50000289400 fastq.gz 29.6 GB
EGAF50000289401 fastq.gz 27.9 GB
EGAF50000289402 fastq.gz 30.9 GB
EGAF50000289403 fastq.gz 32.2 GB
EGAF50000289404 fastq.gz 48.1 GB
EGAF50000289405 fastq.gz 29.9 GB
EGAF50000289406 fastq.gz 44.2 GB
EGAF50000289407 fastq.gz 45.9 GB
EGAF50000289408 fastq.gz 41.1 GB
EGAF50000289409 fastq.gz 34.4 GB
EGAF50000289410 fastq.gz 35.8 GB
EGAF50000289411 fastq.gz 49.9 GB
EGAF50000289412 fastq.gz 30.9 GB
EGAF50000289413 fastq.gz 36.4 GB
EGAF50000289414 fastq.gz 37.8 GB
EGAF50000289415 fastq.gz 42.0 GB
EGAF50000289416 fastq.gz 44.6 GB
EGAF50000289417 fastq.gz 30.3 GB
EGAF50000289418 fastq.gz 32.2 GB
EGAF50000289419 fastq.gz 39.2 GB
EGAF50000289420 fastq.gz 40.4 GB
EGAF50000289421 fastq.gz 33.3 GB
EGAF50000289422 fastq.gz 37.6 GB
EGAF50000289423 fastq.gz 38.6 GB
EGAF50000289424 fastq.gz 36.3 GB
EGAF50000289425 fastq.gz 37.8 GB
EGAF50000289426 fastq.gz 31.5 GB
EGAF50000289427 fastq.gz 32.5 GB
EGAF50000289428 fastq.gz 44.6 GB
EGAF50000289429 fastq.gz 46.1 GB
EGAF50000289430 fastq.gz 56.1 GB
EGAF50000289431 fastq.gz 57.9 GB
EGAF50000289432 fastq.gz 44.8 GB
EGAF50000289433 fastq.gz 41.9 GB
EGAF50000289434 fastq.gz 43.0 GB
EGAF50000289435 fastq.gz 41.6 GB
EGAF50000289436 fastq.gz 42.9 GB
EGAF50000289437 fastq.gz 32.8 GB
EGAF50000289438 fastq.gz 34.3 GB
EGAF50000289439 fastq.gz 44.5 GB
EGAF50000289440 fastq.gz 38.6 GB
EGAF50000289441 fastq.gz 40.5 GB
EGAF50000289442 fastq.gz 58.2 GB
EGAF50000289443 fastq.gz 60.4 GB
EGAF50000289444 fastq.gz 50.3 GB
EGAF50000289445 fastq.gz 52.6 GB
EGAF50000289446 fastq.gz 50.7 GB
EGAF50000289447 fastq.gz 53.2 GB
EGAF50000289448 fastq.gz 40.9 GB
EGAF50000289449 fastq.gz 42.6 GB
EGAF50000289450 fastq.gz 20.6 GB
EGAF50000289451 fastq.gz 28.0 GB
EGAF50000289452 fastq.gz 23.8 GB
EGAF50000289453 fastq.gz 24.7 GB
EGAF50000289454 fastq.gz 31.8 GB
EGAF50000289455 fastq.gz 43.0 GB
EGAF50000289456 fastq.gz 23.4 GB
EGAF50000289457 fastq.gz 36.0 GB
EGAF50000289458 fastq.gz 37.5 GB
EGAF50000289459 fastq.gz 29.5 GB
EGAF50000289460 fastq.gz 30.6 GB
EGAF50000289461 fastq.gz 29.9 GB
EGAF50000289462 fastq.gz 42.9 GB
EGAF50000289463 fastq.gz 39.3 GB
EGAF50000289464 fastq.gz 44.2 GB
EGAF50000289465 fastq.gz 42.6 GB
EGAF50000289466 fastq.gz 43.7 GB
EGAF50000289467 fastq.gz 56.3 GB
EGAF50000289468 fastq.gz 26.8 GB
EGAF50000289469 fastq.gz 27.8 GB
EGAF50000289470 fastq.gz 50.9 GB
EGAF50000289471 fastq.gz 52.8 GB
EGAF50000289472 fastq.gz 31.0 GB
EGAF50000289473 fastq.gz 21.8 GB
EGAF50000289474 fastq.gz 32.4 GB
EGAF50000289475 fastq.gz 46.1 GB
EGAF50000289476 fastq.gz 33.2 GB
EGAF50000289477 fastq.gz 70.3 GB
EGAF50000289478 fastq.gz 34.4 GB
EGAF50000289479 fastq.gz 35.9 GB
EGAF50000289480 fastq.gz 41.6 GB
EGAF50000289481 fastq.gz 43.8 GB
EGAF50000289482 fastq.gz 27.0 GB
EGAF50000289483 fastq.gz 39.4 GB
EGAF50000289484 fastq.gz 33.0 GB
EGAF50000289485 fastq.gz 37.9 GB
EGAF50000289486 fastq.gz 41.4 GB
EGAF50000289487 fastq.gz 34.8 GB
EGAF50000289488 fastq.gz 30.2 GB
EGAF50000289489 fastq.gz 31.5 GB
EGAF50000289490 fastq.gz 34.6 GB
EGAF50000289491 fastq.gz 35.8 GB
EGAF50000289492 fastq.gz 24.9 GB
EGAF50000289493 fastq.gz 25.6 GB
EGAF50000289494 fastq.gz 48.5 GB
EGAF50000289495 fastq.gz 78.3 GB
EGAF50000289496 fastq.gz 83.6 GB
EGAF50000289497 fastq.gz 87.4 GB
EGAF50000289498 fastq.gz 96.3 GB
EGAF50000289499 fastq.gz 24.3 GB
EGAF50000289500 fastq.gz 25.7 GB
EGAF50000289501 fastq.gz 24.6 GB
EGAF50000289502 fastq.gz 27.0 GB
EGAF50000289503 fastq.gz 28.1 GB
EGAF50000289504 fastq.gz 35.1 GB
200 Files (7.8 TB)