About file location

As the EGA is co-managed by the EMBL-EBI and CRG, files could be located in the UK and/or Spain, as indicated by their respective flags.

Alternatively, files could be located in one of the international Federated EGA nodes, as indicated next to the node's flag.
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cfMeDIP-seq profiling of plasma cell-free DNA from metastatic breast cancer patients

This dataset contains raw paired-end FASTQ files generated from cfMeDIP-seq profiling of plasma cell-free DNA from patients with metastatic breast cancer spanning ER-positive/HER2-negative, HER2-positive, and triple-negative breast cancer subtypes (n=87).

Request Access

Access to data generated by UHN is made available by completing the data access agreement for review by the data access committee and will be granted to qualified investigators for appropriate use.

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorised Personnel: The individuals at the User Institution to whom the Data Access Committee (DAC) grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: The Principal Investigator and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. University Health Network: The University Health Network (UHN) is the largest clinical and research hospital in Canada. UHN is affiliated with the University of Toronto and is a member of the Toronto Academic Health Science Network. 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify the DAC within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify the DAC prior to any significant changes to the protocol for the Project. 14. The User Institution will notify the DAC as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. The DAC may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of the province of Ontario and PHIPA. Agreed for User Institution Signature: Name: Title: Date: Principal Investigator I confirm that I have read and understood this Agreement. Signature: Name: Title: Date: Agreed for The Data Access Committee Signature: Name: Title: Date: APPENDIX I – DATASET DETAILS APPENDIX II ––PROJECT DETAILS APPENDIX III –– PUBLICATION POLICY

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000001675 Epigenetics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
i
EGAF50000688462 fastq.gz 7.4 GB
EGAF50000688463 fastq.gz 6.0 GB
EGAF50000688464 fastq.gz 8.4 GB
EGAF50000688465 fastq.gz 7.1 GB
EGAF50000688466 fastq.gz 14.5 GB
EGAF50000688467 fastq.gz 13.3 GB
EGAF50000688468 fastq.gz 6.0 GB
EGAF50000688469 fastq.gz 7.5 GB
EGAF50000688470 fastq.gz 7.5 GB
EGAF50000688471 fastq.gz 7.9 GB
EGAF50000688472 fastq.gz 14.6 GB
EGAF50000688473 fastq.gz 12.6 GB
EGAF50000688474 fastq.gz 15.5 GB
EGAF50000688475 fastq.gz 16.4 GB
EGAF50000688476 fastq.gz 12.7 GB
EGAF50000688477 fastq.gz 12.3 GB
EGAF50000688478 fastq.gz 12.7 GB
EGAF50000688479 fastq.gz 19.5 GB
EGAF50000688480 fastq.gz 7.1 GB
EGAF50000688481 fastq.gz 16.9 GB
EGAF50000688482 fastq.gz 17.4 GB
EGAF50000688483 fastq.gz 13.9 GB
EGAF50000688484 fastq.gz 6.5 GB
EGAF50000688485 fastq.gz 6.9 GB
EGAF50000688486 fastq.gz 8.8 GB
EGAF50000688487 fastq.gz 9.6 GB
EGAF50000688488 fastq.gz 6.2 GB
EGAF50000688489 fastq.gz 4.9 GB
EGAF50000688490 fastq.gz 6.7 GB
EGAF50000688491 fastq.gz 6.1 GB
EGAF50000688492 fastq.gz 12.9 GB
EGAF50000688493 fastq.gz 7.3 GB
EGAF50000688494 fastq.gz 7.7 GB
EGAF50000688495 fastq.gz 7.8 GB
EGAF50000688496 fastq.gz 6.0 GB
EGAF50000688497 fastq.gz 5.8 GB
EGAF50000688498 fastq.gz 7.3 GB
EGAF50000688499 fastq.gz 5.9 GB
EGAF50000688500 fastq.gz 10.2 GB
EGAF50000688501 fastq.gz 6.8 GB
EGAF50000688502 fastq.gz 7.0 GB
EGAF50000688503 fastq.gz 3.9 GB
EGAF50000688504 fastq.gz 7.6 GB
EGAF50000688505 fastq.gz 6.1 GB
EGAF50000688506 fastq.gz 6.8 GB
EGAF50000688507 fastq.gz 6.0 GB
EGAF50000688508 fastq.gz 8.4 GB
EGAF50000688509 fastq.gz 14.5 GB
EGAF50000688510 fastq.gz 7.6 GB
EGAF50000688511 fastq.gz 6.0 GB
EGAF50000688512 fastq.gz 5.9 GB
EGAF50000688513 fastq.gz 7.2 GB
EGAF50000688514 fastq.gz 5.9 GB
EGAF50000688515 fastq.gz 6.3 GB
EGAF50000688516 fastq.gz 6.5 GB
EGAF50000688517 fastq.gz 7.7 GB
EGAF50000688518 fastq.gz 7.2 GB
EGAF50000688519 fastq.gz 7.3 GB
EGAF50000688520 fastq.gz 5.6 GB
EGAF50000688521 fastq.gz 5.7 GB
EGAF50000688522 fastq.gz 7.6 GB
EGAF50000688523 fastq.gz 7.8 GB
EGAF50000688524 fastq.gz 7.4 GB
EGAF50000688525 fastq.gz 5.9 GB
EGAF50000688526 fastq.gz 5.7 GB
EGAF50000688527 fastq.gz 6.0 GB
EGAF50000688528 fastq.gz 6.1 GB
EGAF50000688529 fastq.gz 5.2 GB
EGAF50000688530 fastq.gz 5.6 GB
EGAF50000688531 fastq.gz 12.1 GB
EGAF50000688532 fastq.gz 12.1 GB
EGAF50000688533 fastq.gz 7.4 GB
EGAF50000688534 fastq.gz 7.5 GB
EGAF50000688535 fastq.gz 14.9 GB
EGAF50000688536 fastq.gz 16.3 GB
EGAF50000688537 fastq.gz 17.6 GB
EGAF50000688538 fastq.gz 17.7 GB
EGAF50000688539 fastq.gz 9.8 GB
EGAF50000688540 fastq.gz 11.5 GB
EGAF50000688541 fastq.gz 11.4 GB
EGAF50000688542 fastq.gz 7.9 GB
EGAF50000688543 fastq.gz 10.9 GB
EGAF50000688544 fastq.gz 5.9 GB
EGAF50000688545 fastq.gz 5.9 GB
EGAF50000688546 fastq.gz 5.8 GB
EGAF50000688547 fastq.gz 8.2 GB
EGAF50000688548 fastq.gz 7.3 GB
EGAF50000688549 fastq.gz 7.3 GB
EGAF50000688550 fastq.gz 2.7 GB
EGAF50000688551 fastq.gz 2.8 GB
EGAF50000688552 fastq.gz 14.7 GB
EGAF50000688553 fastq.gz 12.4 GB
EGAF50000688554 fastq.gz 16.2 GB
EGAF50000688555 fastq.gz 6.0 GB
EGAF50000688556 fastq.gz 7.2 GB
EGAF50000688557 fastq.gz 7.5 GB
EGAF50000688558 fastq.gz 8.0 GB
EGAF50000688559 fastq.gz 8.3 GB
EGAF50000688560 fastq.gz 4.8 GB
EGAF50000688561 fastq.gz 6.6 GB
EGAF50000688562 fastq.gz 6.6 GB
EGAF50000688563 fastq.gz 14.4 GB
EGAF50000688564 fastq.gz 6.0 GB
EGAF50000688565 fastq.gz 5.9 GB
EGAF50000688566 fastq.gz 7.6 GB
EGAF50000688567 fastq.gz 8.4 GB
EGAF50000688568 fastq.gz 13.3 GB
EGAF50000688569 fastq.gz 14.7 GB
EGAF50000688570 fastq.gz 14.5 GB
EGAF50000688571 fastq.gz 16.9 GB
EGAF50000688572 fastq.gz 12.7 GB
EGAF50000688573 fastq.gz 12.3 GB
EGAF50000688574 fastq.gz 14.7 GB
EGAF50000688575 fastq.gz 7.1 GB
EGAF50000688576 fastq.gz 12.5 GB
EGAF50000688577 fastq.gz 12.1 GB
EGAF50000688578 fastq.gz 13.2 GB
EGAF50000688579 fastq.gz 13.0 GB
EGAF50000688580 fastq.gz 19.1 GB
EGAF50000688581 fastq.gz 12.3 GB
EGAF50000688582 fastq.gz 13.6 GB
EGAF50000688583 fastq.gz 5.1 GB
EGAF50000688584 fastq.gz 5.3 GB
EGAF50000688585 fastq.gz 7.9 GB
EGAF50000688586 fastq.gz 8.1 GB
EGAF50000688587 fastq.gz 6.6 GB
EGAF50000688588 fastq.gz 9.1 GB
EGAF50000688589 fastq.gz 8.6 GB
EGAF50000688590 fastq.gz 6.1 GB
EGAF50000688591 fastq.gz 5.8 GB
EGAF50000688592 fastq.gz 5.6 GB
EGAF50000688593 fastq.gz 5.8 GB
EGAF50000688594 fastq.gz 12.4 GB
EGAF50000688595 fastq.gz 5.1 GB
EGAF50000688596 fastq.gz 3.9 GB
EGAF50000688597 fastq.gz 5.9 GB
EGAF50000688598 fastq.gz 7.4 GB
EGAF50000688599 fastq.gz 7.6 GB
EGAF50000688600 fastq.gz 9.8 GB
EGAF50000688601 fastq.gz 9.9 GB
EGAF50000688602 fastq.gz 8.7 GB
EGAF50000688603 fastq.gz 11.3 GB
EGAF50000688604 fastq.gz 5.1 GB
EGAF50000688605 fastq.gz 5.9 GB
EGAF50000688606 fastq.gz 4.5 GB
EGAF50000688607 fastq.gz 4.6 GB
EGAF50000688608 fastq.gz 4.9 GB
EGAF50000688609 fastq.gz 9.6 GB
EGAF50000688610 fastq.gz 9.8 GB
EGAF50000688611 fastq.gz 6.6 GB
EGAF50000688612 fastq.gz 6.9 GB
EGAF50000688613 fastq.gz 6.0 GB
EGAF50000688614 fastq.gz 2.8 GB
EGAF50000688615 fastq.gz 2.8 GB
EGAF50000688616 fastq.gz 5.7 GB
EGAF50000688617 fastq.gz 15.8 GB
EGAF50000688618 fastq.gz 13.9 GB
EGAF50000688619 fastq.gz 16.2 GB
EGAF50000688620 fastq.gz 13.7 GB
EGAF50000688621 fastq.gz 7.0 GB
EGAF50000688622 fastq.gz 14.6 GB
EGAF50000688623 fastq.gz 12.4 GB
EGAF50000688624 fastq.gz 12.5 GB
EGAF50000688625 fastq.gz 13.4 GB
EGAF50000688626 fastq.gz 16.0 GB
EGAF50000688627 fastq.gz 12.6 GB
EGAF50000688628 fastq.gz 6.8 GB
EGAF50000688629 fastq.gz 8.5 GB
EGAF50000688630 fastq.gz 7.6 GB
EGAF50000688631 fastq.gz 5.6 GB
EGAF50000688632 fastq.gz 1.6 GB
EGAF50000688633 fastq.gz 15.8 GB
EGAF50000688634 fastq.gz 1.6 GB
EGAF50000688635 fastq.gz 16.0 GB
174 Files (1.6 TB)