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The effect of TNFR2 agonism on human CD4+ T cells, with special focus on Treg cells.

We studied the effect of a human TNFR2 agonist, as compared to control treatments, on human CD4+ T cells, with special focus on the Treg subset. This data set includes: - scRNA/TCR-seq data of CD4+ T cells - bulk RNAseq data of Treg cells

Request Access

DUO:0000021
version: 2021-02-23

ethics approval required

This data use modifier indicates that the requestor must provide documentation of local IRB/ERB approval.

DUO:0000044
version: 2021-02-23

population origins or ancestry research prohibited

This data use modifier indicates use for purposes of population, origin, or ancestry research is prohibited.

Delacher group: Including-commercial worldwide

Data access will only be granted under controlled access upon application to the DAC. The application must include a detailed description of the project for which the data is required (including research goals and planned analyses), a description of the type of data needed, the period of time during which the data will be used, and a description of how the data will be secured. Access will only be possible after the scholarly paper that first uses the data set is published. Recipients will have to provide approval of a local ethics committee. Any attempts to re-identify donors, investigate population origins or perform ancestry research are prohibited. Before data access is granted, recipients need to sign a data transfer agreement, which will be provided to them by the legal department of the University Medical Center of the Johannes Gutenberg University Mainz (Germany). The DAC will moderate contacts with this legal department. By signing the data transfer agreement, recipients will agree on following the EU's data protection laws (GDPR). Furthermore, the legal department may restrict data usage to the specific purpose and analyses stated in the original application. If a donor revokes their consent to data processing or sharing, recipients must immediately delete all data that originated from this donor. In this case, the DAC will inform recipients of the revoked donor consent.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000001974 RNASeq
EGAS50000001975 RNASeq

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF50000928838 fastq.gz 1.8 GB
EGAF50000928839 fastq.gz 24.2 GB
EGAF50000928840 fastq.gz 2.0 GB
EGAF50000928841 fastq.gz 23.2 GB
EGAF50000928842 fastq.gz 24.1 GB
EGAF50000928843 fastq.gz 2.1 GB
EGAF50000928844 fastq.gz 25.1 GB
EGAF50000928845 fastq.gz 1.8 GB
EGAF50000928846 fastq.gz 8.6 GB
EGAF50000928847 fastq.gz 9.0 GB
EGAF50000928848 fastq.gz 787.8 MB
EGAF50000928849 fastq.gz 879.3 MB
EGAF50000928850 fastq.gz 1.3 GB
EGAF50000928851 fastq.gz 1.4 GB
EGAF50000928852 fastq.gz 8.9 GB
EGAF50000928853 fastq.gz 10.0 GB
EGAF50000928854 fastq.gz 1.9 GB
EGAF50000928855 fastq.gz 23.2 GB
EGAF50000928856 fastq.gz 24.4 GB
EGAF50000928857 fastq.gz 2.0 GB
EGAF50000928858 fastq.gz 1.9 GB
EGAF50000928859 fastq.gz 1.9 GB
EGAF50000928860 fastq.gz 21.9 GB
EGAF50000928861 fastq.gz 23.1 GB
EGAF50000928862 fastq.gz 24.3 GB
EGAF50000928863 fastq.gz 25.6 GB
EGAF50000928864 fastq.gz 2.1 GB
EGAF50000928865 fastq.gz 2.0 GB
EGAF50000928866 fastq.gz 856.4 MB
EGAF50000928867 fastq.gz 906.3 MB
EGAF50000928868 fastq.gz 9.1 GB
EGAF50000928869 fastq.gz 8.8 GB
EGAF50000928870 fastq.gz 1.5 GB
EGAF50000928871 fastq.gz 1.4 GB
EGAF50000928872 fastq.gz 10.4 GB
EGAF50000928873 fastq.gz 9.4 GB
EGAF50000928874 fastq.gz 16.8 GB
EGAF50000928875 fastq.gz 1.4 GB
EGAF50000928876 fastq.gz 1.3 GB
EGAF50000928877 fastq.gz 16.0 GB
EGAF50000928878 fastq.gz 1.4 GB
EGAF50000928879 fastq.gz 16.7 GB
EGAF50000928880 fastq.gz 17.5 GB
EGAF50000928881 fastq.gz 1.4 GB
EGAF50000928882 fastq.gz 1.2 GB
EGAF50000928883 fastq.gz 14.1 GB
EGAF50000928884 fastq.gz 1.2 GB
EGAF50000928885 fastq.gz 13.5 GB
EGAF50000928886 fastq.gz 18.3 GB
EGAF50000928887 fastq.gz 1.5 GB
EGAF50000928888 fastq.gz 1.5 GB
EGAF50000928889 fastq.gz 17.3 GB
EGAF50000928890 fastq.gz 339.2 MB
EGAF50000928891 fastq.gz 314.2 MB
EGAF50000928892 fastq.gz 3.5 GB
EGAF50000928893 fastq.gz 3.3 GB
EGAF50000928894 fastq.gz 888.8 MB
EGAF50000928895 fastq.gz 907.4 MB
EGAF50000928896 fastq.gz 8.8 GB
EGAF50000928897 fastq.gz 9.0 GB
EGAF50000928898 fastq.gz 1.2 GB
EGAF50000928899 fastq.gz 1.1 GB
EGAF50000928900 fastq.gz 8.5 GB
EGAF50000928901 fastq.gz 9.7 GB
EGAF50000928902 fastq.gz 1.4 GB
EGAF50000928903 fastq.gz 1.3 GB
EGAF50000928904 fastq.gz 15.7 GB
EGAF50000928905 fastq.gz 16.4 GB
EGAF50000928906 fastq.gz 1.4 GB
EGAF50000928907 fastq.gz 1.4 GB
EGAF50000928908 fastq.gz 16.7 GB
EGAF50000928909 fastq.gz 17.3 GB
EGAF50000928910 fastq.gz 1.4 GB
EGAF50000928911 fastq.gz 1.4 GB
EGAF50000928912 fastq.gz 16.1 GB
EGAF50000928913 fastq.gz 16.8 GB
EGAF50000928914 fastq.gz 1.4 GB
EGAF50000928915 fastq.gz 1.4 GB
EGAF50000928916 fastq.gz 16.7 GB
EGAF50000928917 fastq.gz 17.4 GB
EGAF50000928918 fastq.gz 170.2 MB
EGAF50000928919 fastq.gz 160.4 MB
EGAF50000928920 fastq.gz 1.6 GB
EGAF50000928921 fastq.gz 1.7 GB
EGAF50000928922 fastq.gz 954.6 MB
EGAF50000928923 fastq.gz 9.7 GB
EGAF50000928924 fastq.gz 1.0 GB
EGAF50000928925 fastq.gz 10.4 GB
EGAF50000928926 fq.gz 2.4 GB
EGAF50000928927 fq.gz 2.4 GB
EGAF50000928928 fq.gz 3.2 GB
EGAF50000928929 fq.gz 3.2 GB
EGAF50000928930 fq.gz 2.5 GB
EGAF50000928931 fq.gz 2.5 GB
EGAF50000928932 fq.gz 3.2 GB
EGAF50000928933 fq.gz 3.2 GB
EGAF50000928934 fq.gz 2.7 GB
EGAF50000928935 fq.gz 2.7 GB
EGAF50000928936 fq.gz 3.0 GB
EGAF50000928937 fq.gz 3.0 GB
EGAF50000928938 fq.gz 2.7 GB
EGAF50000928939 fq.gz 2.6 GB
EGAF50000928940 fq.gz 3.7 GB
EGAF50000928941 fq.gz 3.7 GB
EGAF50000928942 fq.gz 2.4 GB
EGAF50000928943 fq.gz 2.5 GB
EGAF50000928944 fq.gz 2.7 GB
EGAF50000928945 fq.gz 2.8 GB
EGAF50000928946 fastq.gz 1.1 GB
EGAF50000928947 fastq.gz 7.3 GB
EGAF50000928948 fastq.gz 1.2 GB
EGAF50000928949 fastq.gz 8.2 GB
EGAF50000928950 fastq.gz 24.5 GB
EGAF50000928951 fastq.gz 2.0 GB
EGAF50000928952 fastq.gz 1.8 GB
EGAF50000928953 fastq.gz 23.6 GB
116 Files (827.7 GB)