MEDIOLA WOO serial tumor RNA sequencing (raw reads)
Poly(A)-selected RNA sequencing of 160 fresh-frozen serial tumor biopsies from 54 patients with stage II/III triple-negative or ER-low breast cancer enrolled in the MEDIOLA window-of-opportunity trial (NCT03594396). Biopsies were obtained at baseline (n = 54), on day 14 after olaparib alone and before durvalumab (n = 54), and on day 29 after olaparib plus a single dose of durvalumab (n = 52). Libraries were prepared with the TruSeq Stranded mRNA LT kit and sequenced as paired-end reads on an Illumina NovaSeq 6000. The dataset comprises 320 paired-end FASTQ files (160 runs), encrypted with Crypt4GH.
- 13/10/2026
- 160 samples
- DAC: EGAC50000001066
- Technology: Illumina NovaSeq 6000
- Archive: European Genome-phenome Archive (EGA)
DUO:0000006 version: 2021-02-23
health or medical or biomedical research
This data use permission indicates that use is allowed for health/medical/biomedical purposes; does not include the study of population origins or ancestry.
DUO:0000019 version: 2021-02-23
publication required
This data use modifier indicates that requestor agrees to make results of studies using the data available to the larger scientific community.
DUO:0000021 version: 2021-02-23
ethics approval required
This data use modifier indicates that the requestor must provide documentation of local IRB/ERB approval.
DUO:0000026 version: 2021-02-23
user specific restriction
This data use modifier indicates that use is limited to use by approved users.
DUO:0000046 version: 2021-02-23
non-commercial use only
This data use modifier indicates that use of the data is limited to not-for-profit use.
MEDIOLA WOO controlled-access data policy
This policy governs access to controlled-access human sequencing data generated by the MEDIOLA window-of-opportunity trial (ESR-16-11923; NCT03594396), a single-arm study of olaparib and durvalumab administered before standard neoadjuvant chemotherapy in patients with stage II/III triple-negative or ER-low breast cancer, conducted at Seoul National University Hospital, Seoul, Republic of Korea. The datasets comprise raw sequencing data (whole-exome sequencing of tumor and matched peripheral-blood germline samples, and RNA sequencing of serial tumor biopsies). Access is restricted to qualified researchers at recognized academic, non-profit, or research institutions, for non-commercial biomedical research consistent with the scope of the original participant consent and with the approvals granted by the Institutional Review Board of Seoul National University Hospital. Applicants must submit a data access request describing the intended research use, together with confirmation of relevant ethical approval at their own institution. Requests are reviewed by the MEDIOLA WOO Data Access Committee (EGAC50000001066). Approved users agree to the following conditions: to use the data solely for the research purpose stated in the approved application; to make no attempt to identify individual participants; not to transfer, share, or redistribute the data to any third party not named in the approved application; to maintain appropriate technical and organizational security measures; to acknowledge the data source and cite the original publication in any resulting work; to destroy the data upon completion of the approved project; and to publish or otherwise make publicly available the results of research conducted using these data.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS50000002019 | Cancer Genomics |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
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|---|---|---|---|---|
| EGAF50000937215 | fastq.gz | 3.5 GB |
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| EGAF50000937218 | fastq.gz | 3.4 GB |
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| EGAF50000937219 | fastq.gz | 3.5 GB |
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| EGAF50000937223 | fastq.gz | 3.9 GB |
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| EGAF50000937224 | fastq.gz | 3.7 GB |
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| EGAF50000937227 | fastq.gz | 4.0 GB |
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| EGAF50000937228 | fastq.gz | 4.1 GB |
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| EGAF50000937229 | fastq.gz | 4.3 GB |
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| EGAF50000937230 | fastq.gz | 4.0 GB |
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| EGAF50000937231 | fastq.gz | 4.3 GB |
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| EGAF50000937232 | fastq.gz | 3.6 GB |
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| EGAF50000937233 | fastq.gz | 3.8 GB |
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| EGAF50000937234 | fastq.gz | 3.4 GB |
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| EGAF50000937235 | fastq.gz | 3.5 GB |
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| EGAF50000937248 | fastq.gz | 4.8 GB |
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| EGAF50000937249 | fastq.gz | 4.9 GB |
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| EGAF50000937250 | fastq.gz | 3.5 GB |
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| EGAF50000937252 | fastq.gz | 3.3 GB |
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| EGAF50000937258 | fastq.gz | 3.2 GB |
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| EGAF50000937259 | fastq.gz | 3.1 GB |
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| EGAF50000937260 | fastq.gz | 3.2 GB |
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| EGAF50000937261 | fastq.gz | 3.1 GB |
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| EGAF50000937262 | fastq.gz | 3.1 GB |
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| EGAF50000937263 | fastq.gz | 3.0 GB |
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| EGAF50000937264 | fastq.gz | 3.0 GB |
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| EGAF50000937266 | fastq.gz | 3.0 GB |
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| EGAF50000937269 | fastq.gz | 3.1 GB |
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| EGAF50000937270 | fastq.gz | 3.1 GB |
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| EGAF50000937272 | fastq.gz | 3.2 GB |
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| EGAF50000937273 | fastq.gz | 3.3 GB |
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| EGAF50000937274 | fastq.gz | 3.4 GB |
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| EGAF50000937275 | fastq.gz | 3.2 GB |
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| EGAF50000937276 | fastq.gz | 3.2 GB |
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| EGAF50000937277 | fastq.gz | 3.2 GB |
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| EGAF50000937278 | fastq.gz | 3.2 GB |
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| EGAF50000937279 | fastq.gz | 3.5 GB |
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| EGAF50000937280 | fastq.gz | 2.9 GB |
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| EGAF50000937281 | fastq.gz | 2.9 GB |
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| EGAF50000937284 | fastq.gz | 3.5 GB |
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| EGAF50000937285 | fastq.gz | 3.3 GB |
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| EGAF50000937290 | fastq.gz | 3.4 GB |
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| EGAF50000937291 | fastq.gz | 3.0 GB |
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| EGAF50000937292 | fastq.gz | 3.0 GB |
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| EGAF50000937293 | fastq.gz | 2.8 GB |
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| EGAF50000937294 | fastq.gz | 3.1 GB |
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| EGAF50000937296 | fastq.gz | 3.3 GB |
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| EGAF50000937297 | fastq.gz | 3.3 GB |
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| EGAF50000937298 | fastq.gz | 3.1 GB |
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| EGAF50000937299 | fastq.gz | 3.1 GB |
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| EGAF50000937300 | fastq.gz | 3.6 GB |
|
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| EGAF50000937301 | fastq.gz | 3.1 GB |
|
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| EGAF50000937302 | fastq.gz | 2.8 GB |
|
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| EGAF50000937303 | fastq.gz | 2.9 GB |
|
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| EGAF50000937304 | fastq.gz | 2.3 GB |
|
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| EGAF50000937307 | fastq.gz | 2.3 GB |
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| EGAF50000937308 | fastq.gz | 3.6 GB |
|
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| EGAF50000937309 | fastq.gz | 3.3 GB |
|
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| EGAF50000937310 | fastq.gz | 3.4 GB |
|
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| EGAF50000937311 | fastq.gz | 2.8 GB |
|
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| EGAF50000937312 | fastq.gz | 3.4 GB |
|
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| EGAF50000937313 | fastq.gz | 3.4 GB |
|
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| EGAF50000937314 | fastq.gz | 3.4 GB |
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| EGAF50000937315 | fastq.gz | 3.2 GB |
|
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| EGAF50000937316 | fastq.gz | 3.2 GB |
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| EGAF50000937317 | fastq.gz | 3.6 GB |
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| EGAF50000937318 | fastq.gz | 3.2 GB |
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| EGAF50000937323 | fastq.gz | 3.1 GB |
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| EGAF50000937324 | fastq.gz | 2.9 GB |
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| EGAF50000937326 | fastq.gz | 3.1 GB |
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| EGAF50000937327 | fastq.gz | 3.4 GB |
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| EGAF50000937328 | fastq.gz | 2.9 GB |
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| EGAF50000937329 | fastq.gz | 3.1 GB |
|
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| EGAF50000937331 | fastq.gz | 3.1 GB |
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| EGAF50000937332 | fastq.gz | 3.1 GB |
|
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| EGAF50000937333 | fastq.gz | 3.5 GB |
|
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| EGAF50000937335 | fastq.gz | 2.8 GB |
|
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| EGAF50000937336 | fastq.gz | 3.5 GB |
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| EGAF50000937337 | fastq.gz | 2.8 GB |
|
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| EGAF50000937339 | fastq.gz | 3.4 GB |
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| EGAF50000937340 | fastq.gz | 3.4 GB |
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| EGAF50000937341 | fastq.gz | 3.0 GB |
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| EGAF50000937342 | fastq.gz | 3.5 GB |
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| EGAF50000937343 | fastq.gz | 2.7 GB |
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| EGAF50000937346 | fastq.gz | 3.6 GB |
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| EGAF50000937347 | fastq.gz | 2.7 GB |
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| EGAF50000937350 | fastq.gz | 3.0 GB |
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| EGAF50000937351 | fastq.gz | 3.4 GB |
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| EGAF50000937352 | fastq.gz | 3.0 GB |
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| EGAF50000937353 | fastq.gz | 3.4 GB |
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| EGAF50000937354 | fastq.gz | 3.0 GB |
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| EGAF50000937355 | fastq.gz | 3.4 GB |
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| EGAF50000937358 | fastq.gz | 3.3 GB |
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| EGAF50000937359 | fastq.gz | 3.3 GB |
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| EGAF50000937360 | fastq.gz | 3.2 GB |
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| EGAF50000937361 | fastq.gz | 3.2 GB |
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| EGAF50000937363 | fastq.gz | 3.3 GB |
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| EGAF50000937364 | fastq.gz | 3.2 GB |
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| EGAF50000937370 | fastq.gz | 3.1 GB |
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| EGAF50000937381 | fastq.gz | 3.2 GB |
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| EGAF50000937382 | fastq.gz | 3.1 GB |
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| EGAF50000937383 | fastq.gz | 2.7 GB |
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| EGAF50000937384 | fastq.gz | 2.8 GB |
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| EGAF50000937385 | fastq.gz | 3.6 GB |
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| EGAF50000937386 | fastq.gz | 3.6 GB |
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| EGAF50000937410 | fastq.gz | 2.9 GB |
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| EGAF50000937411 | fastq.gz | 2.9 GB |
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| EGAF50000937412 | fastq.gz | 2.8 GB |
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| EGAF50000937413 | fastq.gz | 2.8 GB |
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| EGAF50000937442 | fastq.gz | 3.3 GB |
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| EGAF50000937443 | fastq.gz | 3.4 GB |
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| EGAF50000937444 | fastq.gz | 3.4 GB |
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| EGAF50000937445 | fastq.gz | 3.7 GB |
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| EGAF50000937446 | fastq.gz | 3.8 GB |
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| EGAF50000937447 | fastq.gz | 3.9 GB |
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| EGAF50000937448 | fastq.gz | 3.8 GB |
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| EGAF50000937449 | fastq.gz | 3.8 GB |
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| EGAF50000937450 | fastq.gz | 3.4 GB |
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| EGAF50000937451 | fastq.gz | 3.5 GB |
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| EGAF50000937452 | fastq.gz | 3.5 GB |
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| EGAF50000937453 | fastq.gz | 3.9 GB |
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| EGAF50000937454 | fastq.gz | 3.9 GB |
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| EGAF50000937455 | fastq.gz | 3.6 GB |
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| EGAF50000937456 | fastq.gz | 3.7 GB |
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| EGAF50000937457 | fastq.gz | 4.0 GB |
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| EGAF50000937458 | fastq.gz | 3.5 GB |
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| EGAF50000937459 | fastq.gz | 3.6 GB |
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| EGAF50000937460 | fastq.gz | 3.7 GB |
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| EGAF50000937461 | fastq.gz | 3.8 GB |
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| EGAF50000937462 | fastq.gz | 3.5 GB |
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| EGAF50000937463 | fastq.gz | 3.6 GB |
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| EGAF50000937464 | fastq.gz | 3.2 GB |
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| EGAF50000937465 | fastq.gz | 2.7 GB |
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| EGAF50000937466 | fastq.gz | 2.8 GB |
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| EGAF50000937467 | fastq.gz | 2.9 GB |
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| EGAF50000937468 | fastq.gz | 2.9 GB |
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| EGAF50000937469 | fastq.gz | 3.3 GB |
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| EGAF50000937470 | fastq.gz | 2.9 GB |
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| EGAF50000937471 | fastq.gz | 3.0 GB |
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| EGAF50000937472 | fastq.gz | 3.3 GB |
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| EGAF50000937473 | fastq.gz | 3.1 GB |
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| EGAF50000937474 | fastq.gz | 3.0 GB |
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| EGAF50000937475 | fastq.gz | 3.1 GB |
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| EGAF50000937476 | fastq.gz | 3.1 GB |
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| EGAF50000937477 | fastq.gz | 3.1 GB |
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| EGAF50000937478 | fastq.gz | 2.9 GB |
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| EGAF50000937479 | fastq.gz | 2.8 GB |
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| EGAF50000937480 | fastq.gz | 3.4 GB |
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| EGAF50000937481 | fastq.gz | 3.5 GB |
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| EGAF50000937482 | fastq.gz | 2.8 GB |
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| EGAF50000937483 | fastq.gz | 2.8 GB |
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| EGAF50000937484 | fastq.gz | 3.4 GB |
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| EGAF50000937485 | fastq.gz | 3.4 GB |
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| EGAF50000937486 | fastq.gz | 3.0 GB |
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| EGAF50000937487 | fastq.gz | 3.1 GB |
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| EGAF50000937488 | fastq.gz | 3.2 GB |
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| EGAF50000937489 | fastq.gz | 3.3 GB |
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| EGAF50000937490 | fastq.gz | 3.5 GB |
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| EGAF50000937491 | fastq.gz | 2.8 GB |
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| EGAF50000937492 | fastq.gz | 2.9 GB |
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| EGAF50000937493 | fastq.gz | 3.2 GB |
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| EGAF50000937494 | fastq.gz | 3.2 GB |
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| EGAF50000937495 | fastq.gz | 2.9 GB |
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| EGAF50000937496 | fastq.gz | 3.0 GB |
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| EGAF50000937497 | fastq.gz | 3.2 GB |
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| EGAF50000937498 | fastq.gz | 3.2 GB |
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| EGAF50000937499 | fastq.gz | 3.2 GB |
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| EGAF50000937500 | fastq.gz | 3.2 GB |
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| EGAF50000937501 | fastq.gz | 3.3 GB |
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| EGAF50000937502 | fastq.gz | 3.1 GB |
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| EGAF50000937503 | fastq.gz | 3.2 GB |
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| EGAF50000937504 | fastq.gz | 3.1 GB |
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| EGAF50000937505 | fastq.gz | 3.2 GB |
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| EGAF50000937506 | fastq.gz | 3.6 GB |
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| EGAF50000937507 | fastq.gz | 3.6 GB |
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| EGAF50000937508 | fastq.gz | 2.7 GB |
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| EGAF50000937509 | fastq.gz | 2.8 GB |
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| EGAF50000937510 | fastq.gz | 3.2 GB |
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| EGAF50000937511 | fastq.gz | 3.2 GB |
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| EGAF50000937512 | fastq.gz | 3.0 GB |
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| EGAF50000937513 | fastq.gz | 3.1 GB |
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| EGAF50000937514 | fastq.gz | 3.2 GB |
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| EGAF50000937515 | fastq.gz | 3.1 GB |
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| EGAF50000937516 | fastq.gz | 3.2 GB |
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| EGAF50000937517 | fastq.gz | 3.1 GB |
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| EGAF50000937518 | fastq.gz | 3.2 GB |
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| EGAF50000937519 | fastq.gz | 3.4 GB |
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| EGAF50000937520 | fastq.gz | 3.5 GB |
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| EGAF50000937521 | fastq.gz | 3.1 GB |
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| EGAF50000937522 | fastq.gz | 3.1 GB |
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| EGAF50000937523 | fastq.gz | 3.0 GB |
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| EGAF50000937524 | fastq.gz | 3.0 GB |
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| EGAF50000937525 | fastq.gz | 3.0 GB |
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| EGAF50000937526 | fastq.gz | 3.0 GB |
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| EGAF50000937527 | fastq.gz | 2.7 GB |
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| EGAF50000937528 | fastq.gz | 2.8 GB |
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| EGAF50000937529 | fastq.gz | 3.2 GB |
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| EGAF50000937530 | fastq.gz | 3.1 GB |
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| EGAF50000937531 | fastq.gz | 3.2 GB |
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| EGAF50000937532 | fastq.gz | 3.4 GB |
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| EGAF50000937533 | fastq.gz | 3.2 GB |
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| EGAF50000937534 | fastq.gz | 3.4 GB |
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| EGAF50000937535 | fastq.gz | 3.3 GB |
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| EGAF50000937536 | fastq.gz | 3.3 GB |
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| EGAF50000937537 | fastq.gz | 3.4 GB |
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| EGAF50000937538 | fastq.gz | 3.4 GB |
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| EGAF50000937539 | fastq.gz | 3.1 GB |
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| EGAF50000937540 | fastq.gz | 3.1 GB |
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| EGAF50000937541 | fastq.gz | 3.3 GB |
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| EGAF50000937542 | fastq.gz | 3.0 GB |
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| EGAF50000937543 | fastq.gz | 3.1 GB |
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| EGAF50000937544 | fastq.gz | 3.1 GB |
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| EGAF50000937545 | fastq.gz | 3.1 GB |
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| EGAF50000937546 | fastq.gz | 3.2 GB |
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| EGAF50000937547 | fastq.gz | 2.9 GB |
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| EGAF50000937548 | fastq.gz | 3.0 GB |
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| EGAF50000937549 | fastq.gz | 3.4 GB |
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| EGAF50000937550 | fastq.gz | 3.6 GB |
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| EGAF50000937551 | fastq.gz | 3.5 GB |
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| EGAF50000937552 | fastq.gz | 3.6 GB |
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| EGAF50000937553 | fastq.gz | 3.5 GB |
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| EGAF50000937554 | fastq.gz | 3.4 GB |
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| EGAF50000937555 | fastq.gz | 3.2 GB |
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| EGAF50000937556 | fastq.gz | 3.1 GB |
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| EGAF50000937557 | fastq.gz | 3.2 GB |
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| EGAF50000937558 | fastq.gz | 3.4 GB |
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| EGAF50000937559 | fastq.gz | 3.3 GB |
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| EGAF50000937560 | fastq.gz | 2.8 GB |
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| EGAF50000937561 | fastq.gz | 2.9 GB |
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| EGAF50000937562 | fastq.gz | 3.1 GB |
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| EGAF50000937563 | fastq.gz | 3.1 GB |
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| EGAF50000937564 | fastq.gz | 3.1 GB |
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| EGAF50000937565 | fastq.gz | 3.3 GB |
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| EGAF50000937566 | fastq.gz | 3.4 GB |
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| EGAF50000937567 | fastq.gz | 2.8 GB |
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| EGAF50000937568 | fastq.gz | 2.9 GB |
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| EGAF50000937569 | fastq.gz | 3.6 GB |
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| EGAF50000937570 | fastq.gz | 3.3 GB |
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| EGAF50000937571 | fastq.gz | 3.4 GB |
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| EGAF50000937572 | fastq.gz | 3.2 GB |
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| EGAF50000937573 | fastq.gz | 3.1 GB |
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| EGAF50000937574 | fastq.gz | 3.4 GB |
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| EGAF50000937575 | fastq.gz | 3.1 GB |
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| EGAF50000937576 | fastq.gz | 3.0 GB |
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| EGAF50000937577 | fastq.gz | 3.1 GB |
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| EGAF50000937578 | fastq.gz | 3.1 GB |
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| EGAF50000937579 | fastq.gz | 3.3 GB |
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| EGAF50000937580 | fastq.gz | 3.3 GB |
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| EGAF50000937581 | fastq.gz | 3.5 GB |
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| EGAF50000937582 | fastq.gz | 2.7 GB |
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| EGAF50000937583 | fastq.gz | 3.7 GB |
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| EGAF50000937584 | fastq.gz | 3.5 GB |
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| EGAF50000937585 | fastq.gz | 2.9 GB |
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| EGAF50000937586 | fastq.gz | 2.9 GB |
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| EGAF50000937587 | fastq.gz | 3.4 GB |
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| EGAF50000937588 | fastq.gz | 3.5 GB |
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| EGAF50000937589 | fastq.gz | 2.9 GB |
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| EGAF50000937590 | fastq.gz | 2.9 GB |
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| EGAF50000937591 | fastq.gz | 3.3 GB |
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| EGAF50000937592 | fastq.gz | 3.4 GB |
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| EGAF50000937593 | fastq.gz | 2.7 GB |
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| EGAF50000937594 | fastq.gz | 2.8 GB |
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| EGAF50000937595 | fastq.gz | 3.5 GB |
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| EGAF50000937596 | fastq.gz | 3.1 GB |
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| EGAF50000937597 | fastq.gz | 3.2 GB |
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| EGAF50000937598 | fastq.gz | 2.8 GB |
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| EGAF50000937599 | fastq.gz | 3.5 GB |
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| EGAF50000937600 | fastq.gz | 3.3 GB |
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| EGAF50000937601 | fastq.gz | 3.1 GB |
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| EGAF50000937602 | fastq.gz | 3.5 GB |
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| EGAF50000937603 | fastq.gz | 3.6 GB |
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|
| EGAF50000937604 | fastq.gz | 3.3 GB |
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|
| EGAF50000937605 | fastq.gz | 3.3 GB |
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|
| EGAF50000937606 | fastq.gz | 3.4 GB |
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|
| EGAF50000937607 | fastq.gz | 3.5 GB |
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|
| EGAF50000937608 | fastq.gz | 3.2 GB |
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| EGAF50000937609 | fastq.gz | 3.2 GB |
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| EGAF50000937610 | fastq.gz | 3.2 GB |
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| EGAF50000937611 | fastq.gz | 3.1 GB |
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| EGAF50000937612 | fastq.gz | 3.2 GB |
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|
| EGAF50000937613 | fastq.gz | 3.0 GB |
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| EGAF50000937614 | fastq.gz | 3.0 GB |
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| EGAF50000937615 | fastq.gz | 2.9 GB |
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|
| EGAF50000937616 | fastq.gz | 2.9 GB |
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|
| EGAF50000937617 | fastq.gz | 3.4 GB |
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| EGAF50000937618 | fastq.gz | 3.5 GB |
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| EGAF50000937619 | fastq.gz | 3.5 GB |
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| EGAF50000937620 | fastq.gz | 3.6 GB |
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| EGAF50000937621 | fastq.gz | 2.7 GB |
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| EGAF50000937622 | fastq.gz | 2.8 GB |
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| EGAF50000937623 | fastq.gz | 3.2 GB |
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| EGAF50000937624 | fastq.gz | 3.2 GB |
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| EGAF50000937625 | fastq.gz | 3.2 GB |
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| EGAF50000937626 | fastq.gz | 3.3 GB |
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| EGAF50000937693 | fastq.gz | 4.4 GB |
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| EGAF50000937694 | fastq.gz | 3.4 GB |
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| EGAF50000937695 | fastq.gz | 3.5 GB |
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| EGAF50000937702 | fastq.gz | 3.6 GB |
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|
| EGAF50000937704 | fastq.gz | 3.7 GB |
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|
| EGAF50000937706 | fastq.gz | 3.8 GB |
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|
| EGAF50000937707 | fastq.gz | 3.9 GB |
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| EGAF50000937719 | fastq.gz | 4.2 GB |
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|
| EGAF50000937720 | fastq.gz | 3.7 GB |
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|
| EGAF50000937721 | fastq.gz | 3.8 GB |
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|
| EGAF50000937725 | fastq.gz | 3.3 GB |
|
|
| EGAF50000937726 | fastq.gz | 3.5 GB |
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|
| EGAF50000937727 | fastq.gz | 3.6 GB |
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| EGAF50000937728 | fastq.gz | 3.3 GB |
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| EGAF50000937729 | fastq.gz | 3.4 GB |
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|
| EGAF50000937730 | fastq.gz | 3.5 GB |
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|
| EGAF50000937731 | fastq.gz | 3.2 GB |
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|
| EGAF50000937732 | fastq.gz | 3.3 GB |
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|
| EGAF50000937733 | fastq.gz | 3.5 GB |
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|
| EGAF50000937734 | fastq.gz | 3.4 GB |
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| EGAF50000937735 | fastq.gz | 3.6 GB |
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|
| EGAF50000937736 | fastq.gz | 3.3 GB |
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|
| EGAF50000937737 | fastq.gz | 3.0 GB |
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|
| EGAF50000937738 | fastq.gz | 3.0 GB |
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|
| EGAF50000937739 | fastq.gz | 3.1 GB |
|
|
| EGAF50000937740 | fastq.gz | 3.1 GB |
|
|
| EGAF50000937741 | fastq.gz | 3.1 GB |
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|
| 320 Files (1.0 TB) | ||||