5495 results for "*oma"

in 37.30 milliseconds.

• Genome and transcriptome sequence data from a nasopharyngeal carcinoma patient

  Genome and transcriptome sequence data from a nasopharyngeal carcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015896

• Genome and transcriptome sequence data from a metastatic sebaceous gland carcinoma patient

  Genome and transcriptome sequence data from a metastatic sebaceous gland carcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015899

• Genome and transcriptome sequence data from a cervical squamous carcinoma patient

  Genome and transcriptome sequence data from a cervical squamous carcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015900

• Genome and transcriptome sequence data from a adenocarcinoma of the lung patient

  Genome and transcriptome sequence data from a adenocarcinoma of the lung patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015902

• Genome and transcriptome sequence data from a metastatic poorly differentiated (likely basaloid squamous cell) carcinoma of unknown primary patient

  Genome and transcriptome sequence data from a metastatic poorly differentiated (likely basaloid squamous cell) carcinoma of unknown primary patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015904

• Genome and transcriptome sequence data from a metastatic rectal adenocarcinoma patient

  Genome and transcriptome sequence data from a metastatic rectal adenocarcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015906

• Genome and transcriptome sequence data from a lung squamous cell carcinoma patient

  Genome and transcriptome sequence data from a lung squamous cell carcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015907

• Genome and transcriptome sequence data from a metastatic poorly differentiated neuroendocrine carcinoma, pancreatic primary patient

  Genome and transcriptome sequence data from a metastatic poorly differentiated neuroendocrine carcinoma, pancreatic primary patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015910

• Genome and transcriptome sequence data from a metastatic uterine leiomyosarcoma patient

  Genome and transcriptome sequence data from a metastatic uterine leiomyosarcoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015912

• Genome and transcriptome sequence data from a multifocal hepatocellular carcinoma patient

  Genome and transcriptome sequence data from a multifocal hepatocellular carcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015914

• Genome and transcriptome sequence data from a lower lip squamous cell carcinoma patient

  Genome and transcriptome sequence data from a lower lip squamous cell carcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015915

• Genome and transcriptome sequence data from a squamous cell carcinoma of the cervix patient

  Genome and transcriptome sequence data from a squamous cell carcinoma of the cervix patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015916

• Genome and transcriptome sequence data from a unknown primary, cholangiocarcinoma patient

  Genome and transcriptome sequence data from a unknown primary, cholangiocarcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015917

• Genome and transcriptome sequence data from a metastatic invasive ductal carcinoma of the breast patient

  Genome and transcriptome sequence data from a metastatic invasive ductal carcinoma of the breast patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015918

• Genome and transcriptome sequence data from a metastatic anal squamous cell carcinoma patient

  Genome and transcriptome sequence data from a metastatic anal squamous cell carcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015919

• Genome and transcriptome sequence data from a cutaneous squamous cell carcinoma patient

  Genome and transcriptome sequence data from a cutaneous squamous cell carcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015920

• Genome and transcriptome sequence data from a wildtype glioblastoma patient

  Genome and transcriptome sequence data from a wildtype glioblastoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015921

• Genome and transcriptome sequence data from a metastatic recurrence of pancreatic ductal adenocarcinoma patient

  Genome and transcriptome sequence data from a metastatic recurrence of pancreatic ductal adenocarcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015923

• Genome and transcriptome sequence data from a metastatic high grade neuroendocrine carcinoma patient

  Genome and transcriptome sequence data from a metastatic high grade neuroendocrine carcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015926

• Genome and transcriptome sequence data from a metastatic hepatocellular carcinoma patient

  Genome and transcriptome sequence data from a metastatic hepatocellular carcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015927

• Genome and transcriptome sequence data from a squamous cell carcinoma of the vulva patient

  Genome and transcriptome sequence data from a squamous cell carcinoma of the vulva patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015928

• Genome and transcriptome sequence data from a oligodendroglioma patient

  Genome and transcriptome sequence data from a oligodendroglioma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015929

• Genome and transcriptome sequence data from a recurrent salivary gland (myoepithelial carcinoma) patient

  Genome and transcriptome sequence data from a recurrent salivary gland (myoepithelial carcinoma) patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015933

• Genome and transcriptome sequence data from a metastatic osteosarcoma patient

  Genome and transcriptome sequence data from a metastatic osteosarcoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015934

• Genome and transcriptome sequence data from a clear cell carcinoma of the left ovary patient

  Genome and transcriptome sequence data from a clear cell carcinoma of the left ovary patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015987

• Genome and transcriptome sequence data from a cholangiocarcinoma patient

  Genome and transcriptome sequence data from a cholangiocarcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015990

• Genome and transcriptome sequence data from a metastatic minor salivary gland adenoid cystic carcinoma of trachea patient

  Genome and transcriptome sequence data from a metastatic minor salivary gland adenoid cystic carcinoma of trachea patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015992

• Genome and transcriptome sequence data from a metastatic chordoma of the c-spine patient

  Genome and transcriptome sequence data from a metastatic chordoma of the c-spine patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015995

• Genome and transcriptome sequence data from a urothelial carcinoma - primary unknown patient

  Genome and transcriptome sequence data from a urothelial carcinoma - primary unknown patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001015999

• Genome and transcriptome sequence data from a epitheloid angiosarcoma of bone patient

  Genome and transcriptome sequence data from a epitheloid angiosarcoma of bone patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016000

• Genome and transcriptome sequence data from a esthesioneuroblastoma recurrent patient

  Genome and transcriptome sequence data from a esthesioneuroblastoma recurrent patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016001

• Genome and transcriptome sequence data from a metastatic pancreatic adenocarcinoma patient

  Genome and transcriptome sequence data from a metastatic pancreatic adenocarcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016002

• Genome and transcriptome sequence data from a metastatic squamous cell carcinoma patient

  Genome and transcriptome sequence data from a metastatic squamous cell carcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016003

• Genome and transcriptome sequence data from a dedifferentiated liposarcoma patient

  Genome and transcriptome sequence data from a dedifferentiated liposarcoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016008

• Genome and transcriptome sequence data from a sclerosing epithelioid fibrosarcoma patient

  Genome and transcriptome sequence data from a sclerosing epithelioid fibrosarcoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016009

• Genome and transcriptome sequence data from a ewing sarcoma patient

  Genome and transcriptome sequence data from a ewing sarcoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016011

• Genome and transcriptome sequence data from a clear cell carcinoma of the left ovary patient

  Genome and transcriptome sequence data from a clear cell carcinoma of the left ovary patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016012

• Genome and transcriptome sequence data from a metastatic pancreatic adenocarcinoma patient

  Genome and transcriptome sequence data from a metastatic pancreatic adenocarcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016013

• Genome and transcriptome sequence data from a metastatic pancreatic adenocarcinoma patient

  Genome and transcriptome sequence data from a metastatic pancreatic adenocarcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016014

• Genome and transcriptome sequence data from a metastatic adenoid cystic carcinoma of the trachea patient

  Genome and transcriptome sequence data from a metastatic adenoid cystic carcinoma of the trachea patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016015

• Genome and transcriptome sequence data from a radiation induced sarcoma patient

  Genome and transcriptome sequence data from a radiation induced sarcoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016017

• Genome and transcriptome sequence data from a metastatic adenoid cystic carcinoma patient

  Genome and transcriptome sequence data from a metastatic adenoid cystic carcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016018

• Genome and transcriptome sequence data from a metastatic gallbladder adenocarcinoma patient

  Genome and transcriptome sequence data from a metastatic gallbladder adenocarcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016019

• Genome and transcriptome sequence data from a pcgdt-cell lymphoma patient

  Genome and transcriptome sequence data from a pcgdt-cell lymphoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016021

• Genome and transcriptome sequence data from a metastatic ampullary adenocarcinoma patient

  Genome and transcriptome sequence data from a metastatic ampullary adenocarcinoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016025

• Genome and transcriptome sequence data from a adenocarcinoma of the stomach / metastatic gastric cancer patient

  Genome and transcriptome sequence data from a adenocarcinoma of the stomach / metastatic gastric cancer patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016027

• Genome and transcriptome sequence data from a metastatic extra skeletal myxoid chondrosarcoma patient

  Genome and transcriptome sequence data from a metastatic extra skeletal myxoid chondrosarcoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016030

• Genome and transcriptome sequence data from a metastatic melanoma patient

  Genome and transcriptome sequence data from a metastatic melanoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016034

• Genome and transcriptome sequence data from a leiomyosarcoma patient

  Genome and transcriptome sequence data from a leiomyosarcoma patient,generated as part of the BC Cancer Agency's Personalized OncoGenomics (POG) study

  Dataset EGAD00001016036

• Targetable NOTCH1 rearrangements in reninoma

  Reninomas are exceedingly rare renin-secreting kidney tumours that derive from juxtaglomerular cells, specialised smooth muscle cells that reside at the vascular inlet of glomeruli. They are the central component of the juxtaglomerular apparatus which controls systemic blood pressure through the secretion of renin. We assessed somatic changes in reninoma and found structural variants that generate canonical activating rearrangements of NOTCH1, whilst removing its negative regulator, NRARP. Accordingly, in single reninoma nuclei we observed excessive renin and NOTCH1 signalling mRNAs, with a concomitant non-excess of NRARP expression. Re-analysis of previously published reninoma bulk transcriptomes further corroborates our observation of dysregulated Notch pathway signalling in reninoma. Our findings reveal NOTCH1 rearrangements in reninoma, therapeutically targetable through existing NOTCH1 inhibitors, and indicate that unscheduled Notch signalling may be a disease-defining feature of reninoma.

  Dataset EGAD00001010887