2163 results for "2025年12月10日300883股价走势分析"

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• Gene copy number variation in pediatric mental illness in a general population

  We assessed the relationship of gene copy number variation (CNV) in mental health/neurodevelopmental traits and diagnoses, physical health, and cognitive biomarkers in a community sample of 7,100 unrelated European, and East Asian children and youth (Spit for Science). Diagnoses of mental health disorders were found in 17.5% of participants and 27.6% scored in the highest 10% on either or both ADHD and OCD trait measures. Clinically relevant CNVs were present in 3.9% of participants and were associated with elevated scores on a continuous measure of ADHD (p=5.0×10-3), on a cognitive biomarker of mental health (response inhibition (p=1.0×10-2)), and on prevalence of mental disorders (p=1.9×10-6, odds ratio: 3.09). With a rise of mental illness, our data establishes a baseline for delineating genetic contributors in paediatric-onset conditions.

  Study EGAS00001006659

• Targeted capture ctDNA Library CRCQV42Run051-10

  Targeted capture ctDNA Library CRCQV42Run051-10 from patient PBC0001665, plasma sample

  Dataset EGAD00001010804

• Targeted capture ctDNA Library CRCQV40Run027-10

  Targeted capture ctDNA Library CRCQV40Run027-10 from patient PBC0004414, saliva sample

  Dataset EGAD00001010387

• Targeted capture ctDNA Library CRCQV42Run42-10

  Targeted capture ctDNA Library CRCQV42Run42-10 from patient PBC0003643, saliva sample

  Dataset EGAD00001010823

• Dataset of the transcriptomic profiling of skin biopsies from 221 psoriasis patients following treatment with Zasocitinib

  This dataset contains the paired fastq files generated from 221 samples collected from patients with moderate-to-severe plaque psoriasis and sequenced on the Illumina NovaSeq 6000 platform. Patients were randomized in a 1:1:1:1:1 ratio to receive oral Zasocitinib at doses of 2 mg, 5 mg, 15 mg, 30 mg, or placebo once daily for 12 weeks. Clinical response was defined as achieving a PASI 75 response at week 12, while histologic response was defined as the absence of KRT16-positive cells in lesional skin after 12 weeks of treatment.

  Dataset EGAD50000002224

• Targeted capture ctDNA Library CRCQV42Run034-10

  Targeted capture ctDNA Library CRCQV42Run034-10 from patient PBC0004076, buffy coat sample

  Dataset EGAD00001010565

• Targeted capture ctDNA Library CRCQV42Run048-10

  Targeted capture ctDNA Library CRCQV42Run048-10 from patient PBC0001488, buffy coat sample

  Dataset EGAD00001010742

• Targeted capture ctDNA Library CRCQV42Run049-10

  Targeted capture ctDNA Library CRCQV42Run049-10 from patient PBC0004156, buffy coat sample

  Dataset EGAD00001010763

• Targeted capture ctDNA Library CRCQV42Run020-10

  Targeted capture ctDNA Library CRCQV42Run020-10 from patient PBC0001315, plasma baseline sample

  Dataset EGAD00001010425

• Targeted capture ctDNA Library CRCQV42Run033-10

  Targeted capture ctDNA Library CRCQV42Run033-10 from patient PBC0002255, buffy coat sample

  Dataset EGAD00001010549