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• EGAD00000000088

  Gabriel samples from the Karelia Allergy Study

  Dataset EGAD00000000088

• EGAD00000000087

  Gabriel samples from the multicenter GAIN cohort

  Dataset EGAD00000000087

• EGAD00000000086

  Gabriel samples from the multicenter GAIN cohort

  Dataset EGAD00000000086

• EGAD00000000083

  Gabriel samples from the French EGEA Cohort

  Dataset EGAD00000000083

• EGAD00000000082

  Gabriel samples from the French EGEA Cohort

  Dataset EGAD00000000082

• EGAD00000000075

  Gabriel samples from the Swedish BAMSE Cohort

  Dataset EGAD00000000075

• EGAD00000000074

  Gabriel samples from the Swedish BAMSE Cohort

  Dataset EGAD00000000074

• EGAD00000000076

  Gabriel samples from the Australian Bussleton Cohort

  Dataset EGAD00000000076

• EGAD00000000077

  Gabriel samples from the Australian Bussleton Cohort

  Dataset EGAD00000000077

• UK10K_COHORT_ALSPAC REL-2011-12-01

  For information about this sample set, please contact the sample custodian Nic Timpson: N.J.Timpson@bristol.ac.uk

  Dataset EGAD00001000195

• RNA-Seq of 584 DLBCL Cases of Non-China Cohort from Phoenix Clinical Trial

  Standard RNA-Seq datasets. Check the associated paper for more details.

  Dataset EGAD00001008131

• COVID-19 Outpatient Thrombosis Prevention Trial (ACTIV-4B)

  An adaptive randomized double-blind placebo-controlled platform trial to compare the effectiveness of anticoagulation with antiplatelet agents and with placebo to prevent thrombotic events in patients diagnosed with COVID-19 who are not admitted to hospital as COVID-19 related symptoms are currently stable.

  Study phs002710

• Study of Leukemia Stem Cells in B-ALL

  This study focused on the biologic properties of human B acute lymphoblastic leukemia (ALL) stem cells. We used human leukemia cell lines, primary patient specimens, and patient derived xenografts in experiments using ChIP-seq, bulk RNA sequencing, single cell RNA sequencing, and CITE-seq.

  Study phs002492

• NHGRI-Mayo Clinic Whole Genome Sequencing of Aggressive Prostate Tumors

  We collected DNA from fresh frozen prostate tumor samples and matched peripheral blood from 10 subjects with aggressive, Gleason score ≥8 disease. Tumor and normal samples were sequenced on the Illumina HiSeq 2000 to mean depths of 95.3X and 48.3X, respectively.

  Study phs001105

• Application of organoid culture system of human gastrointestinal and thoracic cancer in genome medicine

  In order to establish preclinical models, we have established a kind of lung cancer tumoroids derived from a mucus-producing solid pulmonary adenocarcinoma patient. We performed whole exome sequencing and RNA sequencing to analyze genetic background of the tumoroids.

  Study JGAS000664

• Application of organoid culture system of human gastrointestinal and thoracic cancer in genome medicine

  In order to establish preclinical models, we have established a kind of lung cancer tumoroids derived from a mucus-producing solid pulmonary adenocarcinoma patient. We performed whole exome sequencing and RNA sequencing to analyze genetic background of the tumoroids.

  Study JGAS000653

• intratumor heterogeneity in colorectal adenoma and carcinoma

  To investigate intratumor heterogeneity in precancerous lesions of colorectal cancers (PCRCs), we performed whole-exome sequencing of 53 tumor and 10 matched-normal samples from 10 laterally spreading tumors in the colon and rectum, which were histologically diagnosed as adenoma with/without adenocarcinoma.

  Study JGAS000092

• Treatment of CAR T cells with immunomodulatory metabolites

  Anti-Her2-CAR T cells produced from T cells derived from healthy human donors were treated with DMSO (control) or either of the immunomodulatory metabolites indole‐3‐carboxaldehyde (ICA), valeric acid (VA) and isovaleric acid (IVA) to assess effects on CAR T cell function.

  Study EGAS50000001386

• metastatic uveal melanoma tumour biopsies

  Tumour biopsies were obtained from uveal melanoma patients pre and 16 days post treatment with tebentafusp. Biopsies, which were either snap frozen or put in RNA later, were analysed by bulk RNA sequencing (50 million reads per sample) using the Illumina NovaSeq system.

  Study EGAS50000000864

• metastatic uveal melanoma tumour biopsies (n=35)

  Tumour biopsies were obtained from uveal melanoma patients (n = 35) pre and 16 days post treatment with tebentafusp. Biopsies, which were either snap frozen or put in RNA later, were analysed by bulk RNA sequencing (50 million reads per sample) using the Illumina NovaSeq system.

  Study EGAS50000000836

• Exome sequencing study of cells derived from QHJI14s04 human iPSC secondary cell stock

  Genomic abnormalities of cells used in regenerative medicine should be checked. This study evaluates variants on coding sequences of cells derived from QHJI14s04 human iPSC secondary cell stock. Here we conducted whole exome sequence of three vials from the stock.

  Study EGAS50000000934

• 3D chromatin analysis of clear cell renal cell carcinoma using micro-C

  To investigate the 3D structure of chromatin in ccRCC, we performed micro-C on 3 ccRCC cell lines (786-O, A498, UMRC-2), and 1 normal kidney epithelium cell line (HK-2), cultured under normoxic (20% O2) and hypoxic (0.05% O2) conditions

  Study EGAS50000001323

• Genomic profiling of Rare Tumors Release 2

  Utilizing the rare and unique patient samples provided by Pattern Medicine, LLC, MD Anderson will molecularly characterize rare cancer samples, and potentially generate a collection of preclinical models to enable identification of novel therapeutic targets and concepts, as well as evaluation of innovative treatment strategies.

  Study EGAS50000000615

• Determinants of DNA methylation patterning in human placental development and trophoblast stem cell models.

  To assess whether the DNA methylation landscape of human trophoblast stem cells resembles an in vivo cell type, we used post-bisulfite adaptor-tag sequencing to measure genome-wide DNA methylation of preimplantation human trophectoderm and sorted first trimester cytotrophoblast.

  Study EGAS50000000661

• Single-cell RNA-seq and TCR-seq of synovial tissue and peripheral blood CD4+ and CD8+ T cells from patients with immune-mediated refractory arthritis

  In this study, we investigated CD4+ and CD8+ T lymphocytes from the synovial tissue and peripheral blood of patients with treatment-resistant immune-mediated arthritis using paired single-cell RNA and TCR-sequencing.

  Study EGAS50000000528