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• WES of multi-regional CRC samples

  BAM files of Whole Exome Sequencing (WES) experiment on multi-regional colorectal cancer (CRC) samples. 32 tumour and 16 normal samples corresponding to 16 patients were sequenced, which makes 32 tumour BAMs and 16 normal BAMs (48 BAMs in total).

  Dataset EGAD00001006165

• Hydroxycarbamide effect on gene expression in MPN

  Whole RNA-sequencing of CD34+ cells and neutrophils derived from MPN patients before hydroxycarbamide treatment and after 9-months of treatment. CD34+ cells= 5 patients, 10 samples; neutrophils= 7 patients, 14 samples. Fastq files provided.

  Dataset EGAD00001006330

• RNAseq of NSCLC and melanoma tumor xenografts treated with ADC

  RNAseq of tumours derived from NSCLC (n=3 PDX; n=1 CDX) and melanoma (n=1 CDX) xenograft models treated with ADC or controls (64 samples; 189 FASTQ files).

  Dataset EGAD00001006620

• Tumor transcriptomes of PitNET patients with and without somatostatin analogue treatment before surgery

  Dataset contains fastq files of tumor transcriptomes of 12 pituitary neuroendocrine tumors. Patients with and without somatostatin analogue treatment before tumor surgery can be compared. Sequencing was performed on MGISEQ-2000.

  Dataset EGAD00001006446

• CAGE-seq of frontal post-mortem human brain tissue of patients with FTD and healthy controls

  CAGE-sequencing was performed on frontal post-mortem human brain tissue of patients with FTD caused by mutations in GRN, MAPT or C9orf72 and healthy controls.

  Dataset EGAD00001006843

• CLL ATAC Seq of Untreated and IBET762 treated samples

  CLL PBMC cells were isolated using ficoll gradient. They have been treated with IBET762 or DMSO as solvent control and ATAC Seq has been performed on them.

  Dataset EGAD00001008723

• Novel optineurin frameshift insertion causing familial frontotemporal dementia and parkinsonism without amyotrophic lateral sclerosis

  Novel optineurin frameshift insertion causing familial frontotemporal dementia and parkinsonism without amyotrophic lateral sclerosis

  Dataset EGAD00001007526

• Transcriptome sequencing of rhabdoid tumor tissue, organoids and SMARCB1-reconstituted organoids

  Transcriptome sequencing of rhabdoid tumor tissue, organoids and SMARCB1-reconstituted organoids

  Dataset EGAD00001007948

• Clinical cancer panel sequencing (UCSF500) analysis of TERT promoter duplication in GBM.

  Dataset contains paired-end clinical cancer panel sequencing (UCSF500) data from 2 samples of an initial tumor and one sample of a recurrence from one GBM patient and one sample from a second GBM patient.

  Dataset EGAD00001009286

• Dataset to study clonal evolution in iAMP21 patient SJBALL021901 using scWGS-seq

  scWGS-seq of flow sorted blast and normal cells from SJBALL021901 with 71 high quality cells sequenced (67 blast and 4 normal)

  Dataset EGAD00001009755