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• RRBS melanoma biopsies

  RRBS data for melanoma biopsies at baseline and after treatment

  Dataset EGAD00001009060

• Seminoma exome sequencing

  Exome sequencing data for 8 pairs of seminomas and matched normal

  Dataset EGAD00001001002

• Multisample2 Amplicon

  Amplicon data of tumor samples generated for validation of WES findings and further sub clonal mapping

  Dataset EGAD00001004020

• KRAS Mutations in Multiple Myeloma

  Fastq files for 80 Multiple Myeloma Patients and 12 cell-lines

  Dataset EGAD00001005743

• Familial CEBPA-mutated AML whole exome sequencing dataset

  Whole exome sequencing data for AML and matched normal samples

  Dataset EGAD00001000996

• Melanoma multi site metastases

  These are caveman, pindel, battenberg and brass calls for index patients' metastatic melanoma genomes within this study.

  Dataset EGAD00001005483

• IMpower133 subtype assignments

  This dataset contains subtype assignments for 271 tumor samples profiled by RNA-seq.

  Dataset EGAD00001006926

• RPPA analysis + clinical data

  RPPA analysis from FAIRLANE Trial of Neoadjuvant Ipatasertib Plus Paclitaxel for Triple-Negative Breast Cancer.

  Dataset EGAD00001008507

• Global Anaplastic Thyroid Cancer Initiative

  Raw whole genome sequence data(fastq) for the GATCI project

  Dataset EGAD00001003236

• Recording physiological history of cells with chemical labeling.

  Recordings of the physiological history of cells provide insights into biological processes, yet obtaining such recordings is a challenge. To address this, we introduce a method to record transient cellular events for later analysis. We designed proteins that become labeled in the presence of both a specific cellular activity and a fluorescent substrate. The recording period is set by the presence of the substrate, whereas the cellular activity controls the degree of the labeling. The use of distinguishable substrates enabled the recording of successive periods of activity. We recorded protein-protein interactions, G-protein-coupled receptor activation and elevations in intracellular calcium. Recordings of elevated calcium levels allowed selections of cells from heterogenous populations for transcriptomic analysis and tracking of neuronal activities in flies and zebrafish.

  Study EGAS50000000056