Study
Genome Landscape of Primary Pancreatic Ductal Adenocarcinoma
Study ID | Alternative Stable ID | Type |
---|---|---|
EGAS00001000154 | Other |
Study Description
The purpose of the Australian ICGC Pancreatic Cancer Genome Sequencing Initiativestudy is to identify the common driving mutations underlying the initiation anddevelopment of Pancreatic Adenocarcinoma in a large cohort of pancreatic cancerpatients (n=350). Matched genome sequences will be generated from normal tissue(duodenum) and resected primary tumour tissue in each patient using exome andwhole genome sequencing. The complete repertoire of somatic mutations will bedetermined (substitutions, indels, copy number changes and structural changes).Where possible, matched transcriptome sequencing will also be carried out todetermine locus activity, which mutations are actively expressed and whichrearrangements give rise to gene-fusion transcripts.
Study Datasets 7 datasets.
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
Dataset ID | Description | Technology | Samples |
---|---|---|---|
EGAD00001000049 |
Pancreatic adenocarcinoma QCMG 20110901
|
AB SOLiD 4 System,AB SOLiD System 3.0 | 26 |
EGAD00001000096 |
Pancreatic adenocarcinoma QCMG 20120201
|
AB SOLiD 4 System | 166 |
EGAD00001000323 |
Sequencing data for Australian Pancreatic Cancer study submitted 20130102
|
AB SOLiD 4 System,Illumina HiSeq 2000 | 200 |
EGAD00001000371 |
Sequencing data for PDAC cell lines generated by QCMG
|
Illumina HiSeq 2000,Illumina HiSeq 2500 | 54 |
EGAD00001000660 |
Analysis .bam files from HiSeq sequencing of Australian ICGC PDAC study samples, submitted 20130826
|
353 | |
EGAD00001002192 |
Additional sequencing data for 173 donors in EGAS00001000154, a study of Pancreatic Ductal Adenocarcinoma. WGS libraries were used for high-cellularity cases, WXS sequencing to high depth on low-cellularity cases. HiSeq 2xxx platform was used in all cases. The analysis files associated with this dataset are merged, de-duplicated bams aligned against GRCh37, one tumour and one normal bam per donor.
|
346 | |
EGAD00001003298 |
BAM outputs from RSEM (https://deweylab.github.io/RSEM/) analysis of RNASeq sequencing on HiSeq platform of tumour samples from 95 pancreatic adenocarcinoma cases.
|
96 |
Who archives the data?

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