Study

Genome-wide mutation analysis of germinal-center B-cell derived lymphomas within the ICGC MMML-Seq Consortium

Study ID Alternative Stable ID Type
EGAS00001000394 Other

Study Description

Germinal-center B-cell derived lymphomas (GCB-lymphomas) are the most common B-cell lymphomas in children and adults, with Burkitt Lymphomas (BL) predominating in childhood and follicular lymphoma (FL) and diffuse large B-cell lymphomas (DLBCL) predominating in older age groups. The cell-of-origin in all these lymphomas is supposed to be a germinal center B-cell and transformation of FL in DLBCL or intermediate DLBCL/BL (intL) can occur. In the framework of the German ICGC MMML-Seq we are currently exploring sequencing data of GCB-lymphomas and paired normal controls as well as normal B-cell subsets separated by FACS. This includes whole genome, transcriptome, miRNAome and whole methylome datasets.

Study Datasets 11 datasets.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001000278
ICGC MMML-seq Data Freeze November 2012 whole genome sequencing
Illumina HiSeq 2000 12
EGAD00001000279
ICGC MMML-seq Data Freeze November 2012 whole exome sequencing
Illumina Genome Analyzer IIx 4
EGAD00001000281
ICGC MMML-seq Data Freeze November 2012 transcriptome sequencing
Illumina HiSeq 2000 6
EGAD00001000355
ICGC MMML-seq Data Freeze March 2013 whole genome sequencing
Illumina HiSeq 2000 46
EGAD00001000356
ICGC MMML-seq Data Freeze March 2013 transcriptome sequencing
Illumina HiSeq 2000 23
EGAD00001000645
ICGC MMML-seq Data Freeze July 2013 whole genome sequencing
42
EGAD00001000648
ICGC MMML-seq Data Freeze July 2013 transcriptome sequencing
31
EGAD00001000650
ICGC MMML-seq Data Freeze July 2013 miRNA sequencing
52
EGAD00001001619
miRNA seq data of 43 cases out of dataset EGAD00001000650 (MMML)
43
EGAD00010000377
DNA methylation analysis of 6 primary lymphoma samples
HumanMethylation450k Bead Chip - Genome Studio 6
EGAD00010000379
DNA methylation analysis of 2 peripheral blood samples
HumanMethylation450k Bead Chip - Genome Studio 2

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