Divergence between high metastatic tumor burden and low circulating tumor DNA concentration in metastasized breast cancer
|Study ID||Alternative Stable ID||Type|
Study Datasets 3 datasets.
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In order to establish copy number profiles from the various samples we prepared libraries and subjected them to whole-genome sequencing at a shallow sequencing depth (0.1x)
We utilized exome sequencing for DNA obtained from saliva (germline DNA) and the four spatially separated tumor foci and 3 corresponding lymph node metastases
|Illumina HiSeq 2000||8|
We used targeted deep sequencing to accurately establish the allele frequencies of the mutations identified by exome sequencing