Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001006587	94 sample with multi-omics analysis of ALT-positive neuroblastoma tumors, rna sequencing	HiSeq X Ten Illumina HiSeq 2000 Illumina HiSeq 2500 Illumina HiSeq 4000	715
EGAD00001006625	144 sample from individuals with ALT-positive neuroblastoma tumors, chip-seq sequencing	Illumina HiSeq 2000 Illumina HiSeq 2500	144
EGAD00001006626	238 samples from individuals with ALT-positive neuroblastoma tumors, high coverage whole genome sequencing	HiSeq X Ten Illumina HiSeq 2000 Illumina HiSeq 2500	238
EGAD00001006637	89 samples of individuals with ALT-positive neuroblastoma tumors, exome sequencing	Illumina HiSeq 2500 Illumina HiSeq 4000	89
EGAD00001006638	97 samples of individuals with ALT-positive neuroblastoma tumors, low coverage whole genome sequencing	Illumina HiSeq 2500 Illumina HiSeq 4000	97
EGAD00001006639	63 samples of individuals with ALT-positive neuroblastoma tumors, high coverage whole genome sequencing	HiSeq X Ten	63
EGAD00001006737	Proteome data of neuroblastoma patients		34
EGAD00001006739	None	HiSeq X Ten	17
EGAD00001006785	None	Illumina HiSeq 4000	9

Publications	Citations
Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome. Hartlieb SA, Sieverling L, Nadler-Holly M, Ziehm M, Toprak UH, Herrmann C, Ishaque N, Okonechnikov K, Gartlgruber M, Park YG, Wecht EM, Savelyeva L, Henrich KO, Rosswog C, Fischer M, Hero B, Jones DTW, Pfaff E, Witt O, Pfister SM, Volckmann R, Koster J, Kiesel K, Rippe K, Taschner-Mandl S, Ambros P, Brors B, Selbach M, Feuerbach L, Westermann F. Nat Commun 12: 2021 1269	34
The growing need for controlled data access models in clinical proteomics and metabolomics. Keane TM, O'Donovan C, Vizcaíno JA. Nat Commun 12: 2021 5787	11
MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis. Alborzinia H, Flórez AF, Kreth S, Brückner LM, Yildiz U, Gartlgruber M, Odoni DI, Poschet G, Garbowicz K, Shao C, Klein C, Meier J, Zeisberger P, Nadler-Holly M, Ziehm M, Paul F, Burhenne J, Bell E, Shaikhkarami M, Würth R, Stainczyk SA, Wecht EM, Kreth J, Büttner M, Ishaque N, Schlesner M, Nicke B, Stresemann C, Llamazares-Prada M, Reiling JH, Fischer M, Amit I, Selbach M, Herrmann C, Wölfl S, Henrich KO, Höfer T, Trumpp A, Westermann F. Nat Cancer 3: 2022 471-485	45
Inherited rare variants in homologous recombination and neurodevelopmental genes are associated with increased risk of neuroblastoma. Bonfiglio F, Lasorsa VA, Cantalupo S, D'Alterio G, Aievola V, Boccia A, Ardito M, Furini S, Renieri A, Morini M, Stainczyk S, Westermann F, Paolella G, Eva A, Iolascon A, Capasso M. EBioMedicine 87: 2023 104395	5
Neuroblastoma arises in early fetal development and its evolutionary duration predicts outcome. Körber V, Stainczyk SA, Kurilov R, Henrich KO, Hero B, Brors B, Westermann F, Höfer T. Nat Genet 55: 2023 619-630	5