DAC

SA Pathology Data Access Committee

Dac ID Contact Person Email Access Information
EGAC00001000220 Dr Andreas Schreiber andreas [dot] schreiber [at] adelaide [dot] edu [dot] au No additional information is available

This DAC controls 3 datasets:

Dataset ID Description Technology Samples
EGAD00001000967 This dataset contains the fastq sequencing data collected from bone marrow DNA of a chronic myeloid leukaemia patient at time of diagnosis. Illumina HiSeq 2000 4
EGAD00001004179 This dataset contains WES and RNA-Seq fastq files for 65 CML patient samples at various stages of disease progression. Illumina HiSeq 2000,Illumina HiSeq 2500,NextSeq 500 183
EGAD00001004861 Somatic mutation frequencies in patients with therapy-related myeloid neoplasms (129 patients, 181 samples including bone marrow, mesenchymal stromal cells and hair DNA) and primary myelodysplastic syndrome (108 patients, 215 samples including bone marrow, mesenchymal stromal cells and hair DNA) is assessed by deep sequencing of selected genes, using a Fluidigm Access Array, a Nimblegen capture panel and an Ion AmpliSeq panel. The dataset consists of paired fastq files obtained by either Hiseq (2x101bp) or Nextseq (2x150bp) Illumina sequencing. The mutational burden is found to be similar in both, however the distribution of variants is different. Correlation of the mutational spectrum with prognosis is also observed. Illumina HiSeq 2000,NextSeq 500 396