A somatic reference standard for cancer genome sequencing.
Paired PCR-free whole genome sequencing data of a matched metastatic melanoma cell line (COLO829) and normal across three lineages and across separate institutions, with independent library preparations, sequencing, and analysis. The data was generated with mean mapped coverages of 99X for COLO829 and 103X for the paired normal across three institutions. Overall, common events include >35,000 point mutations, 446 small insertion/deletions, and >6,000 genes affected by copy number changes. We present this reference to the community as an initial standard for enabling quantitative evaluation of somatic mutation pipelines across institutions.
- 13/08/2016
- 24 samples
- DAC: EGAC00001000408
Data Access Policy for COLO829 Somatic reference standard for cancer genome sequencing
Data Use LimitationsThe data will only be used for research purposes.Use of the dataset is limited to scientific research relevant to the etiology, prevention, treatment and late complications or treatment of cancer, including applications proposing analytical methods, software or other research tool development. Use of the dataset is limited to cancer, heart disease, stroke and Alzheimer’s disease research purposes, including applications proposing analytical methods, software or other research tool development.The data will only be used for research purposes.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001001385 | Other |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.