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The mutational landscape of human somatic and germline cells

During the course of a lifetime normal human cells accumulate mutations. Here, using multiple samples from the same individuals we compared the mutational landscape in 29 anatomical structures from soma and the germline. Two ubiquitous mutational signatures, SBS1 and SBS5/40, accounted for the majority of acquired mutations in most cell types but their absolute and relative contributions varied substantially. SBS18, potentially reflecting oxidative damage, and several additional signatures attributed to exogenous and endogenous exposures contributed mutations to subsets of cell types. The mutation rate was lowest in spermatogonia, the stem cell from which sperm are generated and from which most genetic variation in the human population is thought to originate. This was due to low rates of ubiquitous mutation processes and may be partially attributable to a low cell division rate of basal spermatogonia. The results provide important insights into how mutational processes affect the soma and germline.

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001001698 Cancer Genomics
EGAS00001002216 Other
EGAS00001002471 Cancer Genomics
EGAS00001002486 Cancer Genomics
EGAS00001003021 Cancer Genomics
EGAS00001003023 Cancer Genomics
EGAS00001003049 Cancer Genomics
EGAS00001003457 Whole Genome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00001299672 cram 3.5 GB
EGAF00001299673 cram 4.1 GB
EGAF00001299674 cram 4.0 GB
EGAF00001299675 cram 4.4 GB
EGAF00001299676 cram 4.3 GB
EGAF00001299677 cram 3.7 GB
EGAF00001299678 cram 3.9 GB
EGAF00001299679 cram 3.6 GB
EGAF00001299680 cram 3.9 GB
EGAF00001299681 cram 3.6 GB
EGAF00001299682 cram 4.3 GB
EGAF00001299683 cram 4.1 GB
EGAF00001299684 cram 4.6 GB
EGAF00001299685 cram 4.4 GB
EGAF00001299686 cram 3.9 GB
EGAF00001299687 cram 4.0 GB
EGAF00001299688 cram 3.8 GB
EGAF00001299689 cram 3.8 GB
EGAF00001299690 cram 3.5 GB
EGAF00001299691 cram 4.1 GB
EGAF00001299692 cram 4.0 GB
EGAF00001299693 cram 4.5 GB
EGAF00001299694 cram 4.3 GB
EGAF00001299695 cram 3.7 GB
EGAF00001299696 cram 3.9 GB
EGAF00001299697 cram 3.6 GB
EGAF00001299698 cram 3.9 GB
EGAF00001299699 cram 3.6 GB
EGAF00001299700 cram 4.2 GB
EGAF00001299701 cram 4.1 GB
EGAF00001299702 cram 4.6 GB
EGAF00001299703 cram 4.4 GB
EGAF00001299704 cram 3.8 GB
EGAF00001299705 cram 4.0 GB
EGAF00001299706 cram 3.7 GB
EGAF00001303339 cram 4.3 GB
EGAF00001303340 cram 4.2 GB
EGAF00001303341 cram 4.4 GB
EGAF00001303342 cram 4.2 GB
EGAF00001303343 cram 4.7 GB
EGAF00001303344 cram 4.8 GB
EGAF00001303345 cram 4.2 GB
EGAF00001303346 cram 5.0 GB
EGAF00001303347 cram 3.8 GB
EGAF00001303348 cram 3.6 GB
EGAF00001303349 cram 4.2 GB
EGAF00001303350 cram 4.1 GB
EGAF00001303351 cram 4.5 GB
EGAF00001303352 cram 4.3 GB
EGAF00001303353 cram 3.8 GB
EGAF00001303354 cram 3.9 GB
EGAF00001303355 cram 3.7 GB
EGAF00001303356 cram 3.8 GB
EGAF00001305006 cram 4.1 GB
EGAF00001305007 cram 5.1 GB
EGAF00001305008 cram 4.6 GB
EGAF00001305009 cram 4.6 GB
EGAF00001305010 cram 5.6 GB
EGAF00001305011 cram 5.4 GB
EGAF00001305012 cram 5.4 GB
EGAF00001305013 cram 5.9 GB
EGAF00001305014 cram 4.2 GB
EGAF00001305015 cram 5.3 GB
EGAF00001305016 cram 4.7 GB
EGAF00001305017 cram 4.7 GB
EGAF00001305018 cram 5.8 GB
EGAF00001305019 cram 5.5 GB
EGAF00001305020 cram 5.6 GB
EGAF00001305021 cram 6.1 GB
EGAF00001305022 cram 5.0 GB
EGAF00001305023 cram 4.9 GB
EGAF00001305024 cram 5.0 GB
EGAF00001305025 cram 4.8 GB
EGAF00001305026 cram 5.5 GB
EGAF00001305027 cram 5.4 GB
EGAF00001305028 cram 4.8 GB
EGAF00001305029 cram 5.7 GB
EGAF00001305030 cram 4.9 GB
EGAF00001305031 cram 4.8 GB
EGAF00001305032 cram 5.0 GB
EGAF00001305033 cram 4.8 GB
EGAF00001305034 cram 5.5 GB
EGAF00001305869 cram 5.4 GB
EGAF00001305870 cram 4.8 GB
EGAF00001305871 cram 5.6 GB
EGAF00001305872 cram 5.1 GB
EGAF00001305873 cram 5.0 GB
EGAF00001305874 cram 5.1 GB
EGAF00001305875 cram 4.9 GB
EGAF00001305876 cram 5.7 GB
EGAF00001305877 cram 5.5 GB
EGAF00001305878 cram 4.9 GB
EGAF00001305879 cram 5.7 GB
EGAF00001305880 cram 4.8 GB
EGAF00001305881 cram 4.8 GB
EGAF00001305882 cram 5.0 GB
EGAF00001305883 cram 4.8 GB
EGAF00001305884 cram 5.4 GB
EGAF00001305885 cram 5.4 GB
EGAF00001305886 cram 4.8 GB
EGAF00001305887 cram 5.6 GB
EGAF00001305888 cram 5.1 GB
EGAF00001305889 cram 5.6 GB
EGAF00001305890 cram 4.8 GB
EGAF00001305891 cram 5.0 GB
EGAF00001305892 cram 5.2 GB
EGAF00001305893 cram 4.6 GB
EGAF00001305894 cram 4.9 GB
EGAF00001305895 cram 5.1 GB
EGAF00001305896 cram 5.3 GB
EGAF00001305897 cram 5.8 GB
EGAF00001306890 cram 3.4 GB
EGAF00001306891 cram 3.1 GB
EGAF00001306892 cram 3.7 GB
EGAF00001306893 cram 3.5 GB
EGAF00001306894 cram 3.9 GB
EGAF00001306895 cram 3.8 GB
EGAF00001306896 cram 3.3 GB
EGAF00001306897 cram 3.5 GB
EGAF00001306898 cram 3.2 GB
EGAF00001306899 cram 3.4 GB
EGAF00001306900 cram 3.1 GB
EGAF00001306901 cram 3.7 GB
EGAF00001306902 cram 3.5 GB
EGAF00001306903 cram 3.9 GB
EGAF00001306904 cram 3.9 GB
EGAF00001306905 cram 3.3 GB
EGAF00001306906 cram 3.5 GB
EGAF00001306907 cram 3.3 GB
EGAF00001306908 cram 3.5 GB
EGAF00001306909 cram 3.2 GB
EGAF00001306910 cram 3.8 GB
EGAF00001306911 cram 3.7 GB
EGAF00001306912 cram 4.0 GB
EGAF00001306913 cram 4.0 GB
EGAF00001306914 cram 3.5 GB
EGAF00001306915 cram 3.6 GB
EGAF00001306916 cram 3.4 GB
EGAF00001306917 cram 3.5 GB
EGAF00001306918 cram 3.2 GB
EGAF00001306919 cram 5.0 GB
EGAF00001306920 cram 5.2 GB
EGAF00001306921 cram 5.4 GB
EGAF00001306922 cram 4.9 GB
EGAF00001306923 cram 5.0 GB
EGAF00001306924 cram 5.3 GB
EGAF00001306925 cram 5.4 GB
EGAF00001306926 cram 5.8 GB
EGAF00001306927 cram 5.0 GB
EGAF00001306928 cram 5.3 GB
EGAF00001306929 cram 5.4 GB
EGAF00001306930 cram 4.9 GB
EGAF00001306931 cram 5.1 GB
EGAF00001306932 cram 5.4 GB
EGAF00001306933 cram 5.3 GB
EGAF00001306934 cram 5.7 GB
EGAF00001306935 cram 5.0 GB
EGAF00001306936 cram 5.2 GB
EGAF00001306937 cram 5.4 GB
EGAF00001306938 cram 4.8 GB
EGAF00001306939 cram 4.9 GB
EGAF00001306940 cram 5.2 GB
EGAF00001306941 cram 5.2 GB
EGAF00001306942 cram 5.0 GB
EGAF00001306943 cram 5.3 GB
EGAF00001306944 cram 5.0 GB
EGAF00001306945 cram 5.8 GB
EGAF00001306946 cram 5.6 GB
EGAF00001306947 cram 5.0 GB
EGAF00001306948 cram 5.9 GB
EGAF00001306949 cram 5.1 GB
EGAF00001306950 cram 5.0 GB
EGAF00001306951 cram 5.2 GB
EGAF00001306952 cram 4.9 GB
EGAF00001306953 cram 5.7 GB
EGAF00001306954 cram 5.5 GB
EGAF00001306955 cram 5.0 GB
EGAF00001306956 cram 5.8 GB
EGAF00001306957 cram 4.9 GB
EGAF00001306958 cram 4.8 GB
EGAF00001306959 cram 5.1 GB
EGAF00001306960 cram 4.8 GB
EGAF00001306961 cram 5.4 GB
EGAF00001306962 cram 5.4 GB
EGAF00001306963 cram 4.8 GB
EGAF00001306964 cram 5.7 GB
EGAF00001307677 cram 3.7 GB
EGAF00001307678 cram 3.6 GB
EGAF00001307679 cram 4.0 GB
EGAF00001307680 cram 4.0 GB
EGAF00001307681 cram 3.4 GB
EGAF00001307682 cram 3.6 GB
EGAF00001307683 cram 3.3 GB
EGAF00001307684 cram 3.8 GB
EGAF00001307685 cram 4.3 GB
EGAF00001307686 cram 3.5 GB
EGAF00001307687 cram 3.9 GB
EGAF00001307688 cram 3.9 GB
EGAF00001307689 cram 3.5 GB
EGAF00001307690 cram 3.9 GB
EGAF00001307691 cram 4.0 GB
EGAF00001307692 cram 3.9 GB
EGAF00001307693 cram 4.5 GB
EGAF00001307694 cram 3.7 GB
EGAF00001307695 cram 4.1 GB
EGAF00001307696 cram 4.1 GB
EGAF00001307697 cram 3.6 GB
EGAF00001307698 cram 4.0 GB
EGAF00001307699 cram 4.2 GB
EGAF00001307700 cram 3.9 GB
EGAF00001307701 cram 4.4 GB
EGAF00001307702 cram 3.7 GB
EGAF00001307703 cram 4.0 GB
EGAF00001307704 cram 4.0 GB
EGAF00001307705 cram 3.6 GB
EGAF00001307706 cram 4.0 GB
EGAF00001307707 cram 4.1 GB
EGAF00001307708 cram 4.0 GB
EGAF00001307709 cram 4.5 GB
EGAF00001307710 cram 3.8 GB
EGAF00001307711 cram 4.1 GB
EGAF00001307712 cram 4.1 GB
EGAF00001307713 cram 3.8 GB
EGAF00001307714 cram 4.0 GB
EGAF00001307715 cram 4.1 GB
EGAF00001307716 cram 3.3 GB
EGAF00001307717 cram 3.8 GB
EGAF00001307718 cram 3.7 GB
EGAF00001307719 cram 3.4 GB
EGAF00001307720 cram 4.1 GB
EGAF00001307721 cram 4.0 GB
EGAF00001307722 cram 3.9 GB
EGAF00001307723 cram 4.3 GB
EGAF00001307724 cram 3.3 GB
EGAF00001307725 cram 3.9 GB
EGAF00001307726 cram 3.7 GB
EGAF00001307727 cram 3.5 GB
EGAF00001307728 cram 4.2 GB
EGAF00001307729 cram 4.0 GB
EGAF00001307730 cram 4.0 GB
EGAF00001307731 cram 4.4 GB
EGAF00001307732 cram 3.3 GB
EGAF00001307733 cram 4.0 GB
EGAF00001307734 cram 3.6 GB
EGAF00001307735 cram 3.6 GB
EGAF00001307736 cram 4.3 GB
EGAF00001307737 cram 4.0 GB
EGAF00001307738 cram 4.2 GB
EGAF00001307739 cram 4.6 GB
EGAF00001307740 cram 3.4 GB
EGAF00001307741 cram 4.0 GB
EGAF00001307742 cram 3.7 GB
EGAF00001307743 cram 3.6 GB
EGAF00001307744 cram 4.2 GB
EGAF00001307745 cram 4.0 GB
EGAF00001307746 cram 4.1 GB
EGAF00001307747 cram 4.5 GB
EGAF00001307748 cram 3.9 GB
EGAF00001307749 cram 4.8 GB
EGAF00001307750 cram 4.3 GB
EGAF00001307751 cram 4.3 GB
EGAF00001307752 cram 5.2 GB
EGAF00001307753 cram 5.0 GB
EGAF00001307754 cram 5.1 GB
EGAF00001307755 cram 5.5 GB
EGAF00001307756 cram 4.0 GB
EGAF00001307757 cram 5.0 GB
EGAF00001307758 cram 4.5 GB
EGAF00001307759 cram 4.5 GB
EGAF00001307760 cram 5.5 GB
EGAF00001307761 cram 5.3 GB
EGAF00001307762 cram 5.3 GB
EGAF00001307763 cram 5.8 GB
EGAF00002306660 cram 5.1 GB
EGAF00002306661 cram 5.2 GB
EGAF00002306662 cram 5.6 GB
EGAF00002306664 cram 5.2 GB
EGAF00002306665 cram 4.9 GB
EGAF00002306666 cram 5.2 GB
EGAF00002306667 cram 5.4 GB
EGAF00002306668 cram 5.8 GB
EGAF00002306670 cram 5.3 GB
EGAF00002306671 cram 5.0 GB
EGAF00002306673 cram 4.8 GB
EGAF00002306674 cram 5.3 GB
EGAF00002306675 cram 4.8 GB
EGAF00002306676 cram 5.1 GB
EGAF00002306677 cram 5.7 GB
EGAF00002306679 cram 4.8 GB
EGAF00002306680 cram 5.4 GB
EGAF00002306681 cram 4.8 GB
EGAF00002306682 cram 5.2 GB
EGAF00002306683 cram 5.7 GB
EGAF00002306685 cram 4.8 GB
EGAF00002306686 cram 5.4 GB
EGAF00002306687 cram 4.8 GB
EGAF00002306688 cram 5.2 GB
EGAF00002306689 cram 5.7 GB
EGAF00002306691 cram 4.9 GB
EGAF00002306692 cram 5.4 GB
EGAF00002306693 cram 4.8 GB
EGAF00002306694 cram 5.2 GB
EGAF00002306695 cram 5.8 GB
EGAF00002306697 cram 4.8 GB
EGAF00002306698 cram 5.3 GB
EGAF00002306699 cram 4.8 GB
EGAF00002306700 cram 5.1 GB
EGAF00002306701 cram 5.6 GB
EGAF00002306703 cram 4.9 GB
EGAF00002306704 cram 5.4 GB
EGAF00002306705 cram 4.8 GB
EGAF00002306706 cram 5.2 GB
EGAF00002306707 cram 5.7 GB
EGAF00002306935 cram 4.4 GB
EGAF00002306936 cram 3.7 GB
EGAF00002306937 cram 4.0 GB
EGAF00002306942 cram 4.5 GB
EGAF00002306943 cram 3.6 GB
EGAF00002306944 cram 4.0 GB
EGAF00002306949 cram 4.4 GB
EGAF00002306950 cram 3.6 GB
EGAF00002306951 cram 3.9 GB
EGAF00002306956 cram 4.3 GB
EGAF00002306957 cram 3.6 GB
EGAF00002306958 cram 3.8 GB
EGAF00002306961 cram 4.2 GB
EGAF00002306962 cram 3.8 GB
EGAF00002306963 cram 4.9 GB
EGAF00002306964 cram 5.6 GB
EGAF00002306965 cram 5.7 GB
EGAF00002306966 cram 3.9 GB
EGAF00002306967 cram 4.6 GB
EGAF00002306968 cram 5.3 GB
EGAF00002306969 cram 4.2 GB
EGAF00002306970 cram 3.9 GB
EGAF00002306971 cram 4.9 GB
EGAF00002306972 cram 5.5 GB
EGAF00002306973 cram 5.7 GB
EGAF00002306974 cram 3.9 GB
EGAF00002306975 cram 4.6 GB
EGAF00002306976 cram 5.2 GB
EGAF00002306977 cram 4.2 GB
EGAF00002307077 cram 4.2 GB
EGAF00002307079 cram 5.3 GB
EGAF00002307080 cram 5.7 GB
EGAF00002307084 cram 4.3 GB
EGAF00002307086 cram 5.1 GB
EGAF00002307087 cram 5.6 GB
EGAF00002307091 cram 4.1 GB
EGAF00002307093 cram 5.2 GB
EGAF00002307094 cram 5.5 GB
EGAF00002307098 cram 4.2 GB
EGAF00002307100 cram 5.0 GB
EGAF00002307101 cram 5.4 GB
EGAF00002307105 cram 4.1 GB
EGAF00002307110 cram 3.3 GB
EGAF00002307112 cram 3.5 GB
EGAF00002307113 cram 3.5 GB
EGAF00002307120 cram 3.3 GB
EGAF00002307122 cram 3.5 GB
EGAF00002307123 cram 3.5 GB
EGAF00002307130 cram 3.3 GB
EGAF00002307132 cram 3.5 GB
EGAF00002307133 cram 3.5 GB
EGAF00002307135 cram 3.3 GB
EGAF00002307136 cram 3.4 GB
EGAF00002307137 cram 3.6 GB
EGAF00002307140 cram 2.7 GB
EGAF00002307141 cram 3.9 GB
EGAF00002307142 cram 3.0 GB
EGAF00002307143 cram 3.7 GB
EGAF00002307145 cram 2.7 GB
EGAF00002307153 cram 3.8 GB
EGAF00002307156 cram 2.9 GB
EGAF00002307157 cram 4.2 GB
EGAF00002307158 cram 3.3 GB
EGAF00002307159 cram 4.0 GB
EGAF00002307161 cram 3.0 GB
EGAF00002307162 cram 3.8 GB
EGAF00002307166 cram 4.2 GB
EGAF00002307167 cram 3.5 GB
EGAF00002307168 cram 3.7 GB
EGAF00002307169 cram 3.7 GB
EGAF00002307170 cram 4.8 GB
EGAF00002307171 cram 5.4 GB
EGAF00002307172 cram 5.4 GB
EGAF00002307173 cram 3.7 GB
EGAF00002307174 cram 4.6 GB
EGAF00002307175 cram 5.3 GB
EGAF00002307176 cram 4.0 GB
EGAF00002307177 cram 3.7 GB
EGAF00002307178 cram 4.8 GB
EGAF00002307179 cram 5.4 GB
EGAF00002307180 cram 5.5 GB
EGAF00002307181 cram 3.8 GB
EGAF00002307182 cram 4.5 GB
EGAF00002307183 cram 5.2 GB
EGAF00002307184 cram 4.0 GB
EGAF00002307185 cram 3.6 GB
EGAF00002307186 cram 4.7 GB
EGAF00002307187 cram 5.4 GB
EGAF00002307188 cram 5.4 GB
EGAF00002307189 cram 3.7 GB
EGAF00002307190 cram 4.5 GB
EGAF00002307191 cram 5.2 GB
EGAF00002307192 cram 4.0 GB
EGAF00002307281 cram 5.1 GB
EGAF00002307282 cram 5.4 GB
EGAF00002307286 cram 4.1 GB
EGAF00002307288 cram 4.9 GB
EGAF00002307289 cram 5.2 GB
EGAF00002307293 cram 4.0 GB
EGAF00002307314 cram 3.3 GB
EGAF00002307316 cram 3.5 GB
EGAF00002307317 cram 3.5 GB
EGAF00002307324 cram 3.3 GB
EGAF00002307326 cram 3.5 GB
EGAF00002307327 cram 3.5 GB
EGAF00002307334 cram 3.3 GB
EGAF00002307336 cram 3.5 GB
EGAF00002307337 cram 3.5 GB
EGAF00002307339 cram 3.6 GB
EGAF00002307340 cram 4.1 GB
EGAF00002307342 cram 3.2 GB
EGAF00002307343 cram 3.7 GB
EGAF00002307346 cram 3.0 GB
EGAF00002307347 cram 4.2 GB
EGAF00002307348 cram 3.4 GB
EGAF00002307349 cram 4.0 GB
EGAF00002307351 cram 3.1 GB
EGAF00002307352 cram 3.7 GB
EGAF00002307355 cram 3.0 GB
EGAF00002307356 cram 4.2 GB
EGAF00002307357 cram 3.4 GB
EGAF00002307358 cram 3.9 GB
EGAF00002307360 cram 3.1 GB
EGAF00002307361 cram 3.7 GB
EGAF00002307364 cram 2.9 GB
EGAF00002307365 cram 4.2 GB
EGAF00002307366 cram 3.3 GB
EGAF00002307367 cram 4.0 GB
EGAF00002307368 cram 5.1 GB
EGAF00002307369 cram 7.2 GB
EGAF00002307370 cram 7.4 GB
EGAF00002307371 cram 7.6 GB
EGAF00002307372 cram 9.1 GB
EGAF00002307373 cram 5.1 GB
EGAF00002307374 cram 7.2 GB
EGAF00002307375 cram 7.4 GB
EGAF00002307376 cram 7.6 GB
EGAF00002307377 cram 9.1 GB
EGAF00002307378 cram 5.1 GB
EGAF00002307379 cram 7.3 GB
EGAF00002307380 cram 7.4 GB
EGAF00002307381 cram 7.7 GB
EGAF00002307382 cram 9.2 GB
EGAF00002307383 cram 5.1 GB
EGAF00002307384 cram 7.3 GB
EGAF00002307385 cram 7.5 GB
EGAF00002307386 cram 7.7 GB
EGAF00002307387 cram 9.2 GB
EGAF00002307388 cram 5.2 GB
EGAF00002307389 cram 7.4 GB
EGAF00002307390 cram 7.5 GB
EGAF00002307391 cram 7.8 GB
EGAF00002307392 cram 9.2 GB
EGAF00002307393 cram 6.3 GB
EGAF00002307394 cram 5.8 GB
EGAF00002307395 cram 4.2 GB
EGAF00002307414 cram 5.1 GB
EGAF00002307415 cram 5.5 GB
EGAF00002307419 cram 4.1 GB
EGAF00002307421 cram 5.1 GB
EGAF00002307422 cram 5.6 GB
EGAF00002307426 cram 5.7 GB
EGAF00002307427 cram 5.1 GB
EGAF00002307428 cram 3.8 GB
EGAF00002307430 cram 4.1 GB
EGAF00002307431 cram 4.1 GB
EGAF00002307432 cram 4.2 GB
EGAF00002307434 cram 5.8 GB
EGAF00002307435 cram 5.3 GB
EGAF00002307436 cram 4.0 GB
EGAF00002307438 cram 4.3 GB
EGAF00002307439 cram 4.2 GB
EGAF00002307440 cram 4.3 GB
EGAF00002307442 cram 5.8 GB
EGAF00002307443 cram 5.2 GB
EGAF00002307444 cram 3.9 GB
EGAF00002307446 cram 4.2 GB
EGAF00002307447 cram 4.2 GB
EGAF00002307448 cram 4.2 GB
EGAF00002307450 cram 5.7 GB
EGAF00002307451 cram 5.2 GB
EGAF00002307452 cram 3.9 GB
EGAF00002307454 cram 4.2 GB
EGAF00002307494 cram 6.9 GB
EGAF00002307500 cram 7.0 GB
EGAF00002307506 cram 6.8 GB
EGAF00002307512 cram 6.9 GB
EGAF00002307517 cram 7.3 GB
EGAF00002307523 cram 7.2 GB
EGAF00002307529 cram 7.7 GB
EGAF00002307535 cram 7.5 GB
EGAF00002307542 cram 4.7 GB
EGAF00002307543 cram 4.7 GB
EGAF00002307544 cram 4.9 GB
EGAF00002307546 cram 6.6 GB
EGAF00002307547 cram 6.1 GB
EGAF00002307548 cram 4.5 GB
EGAF00002307550 cram 4.9 GB
EGAF00002307551 cram 4.9 GB
EGAF00002307552 cram 5.1 GB
EGAF00002307554 cram 6.5 GB
EGAF00002307555 cram 6.0 GB
EGAF00002307556 cram 4.4 GB
EGAF00002307558 cram 4.8 GB
EGAF00002307559 cram 4.8 GB
EGAF00002307560 cram 5.0 GB
EGAF00002307562 cram 3.9 GB
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EGAF00002307568 cram 4.1 GB
EGAF00002307569 cram 5.0 GB
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EGAF00002307586 cram 3.5 GB
EGAF00002307587 cram 3.4 GB
EGAF00002307594 cram 3.2 GB
EGAF00002307596 cram 3.5 GB
EGAF00002307597 cram 3.4 GB
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EGAF00002307612 cram 6.6 GB
EGAF00002307617 cram 6.9 GB
EGAF00002307618 cram 6.5 GB
EGAF00002307623 cram 6.9 GB
EGAF00002307624 cram 6.6 GB
EGAF00002307661 cram 4.8 GB
EGAF00002307662 cram 3.9 GB
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EGAF00002307668 cram 3.8 GB
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EGAF00002307672 cram 4.8 GB
EGAF00002307673 cram 4.8 GB
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EGAF00002307678 cram 4.8 GB
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EGAF00002307685 cram 4.8 GB
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EGAF00002307708 cram 4.1 GB
EGAF00002307709 cram 4.9 GB
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EGAF00002307714 cram 4.1 GB
EGAF00002307715 cram 5.1 GB
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EGAF00002307720 cram 4.0 GB
EGAF00002307721 cram 4.9 GB
EGAF00002307725 cram 3.3 GB
EGAF00002307726 cram 4.0 GB
EGAF00002307727 cram 4.8 GB
EGAF00002307731 cram 3.3 GB
EGAF00002307732 cram 3.9 GB
EGAF00002307733 cram 4.8 GB
EGAF00002307734 cram 4.2 GB
EGAF00002307735 cram 4.3 GB
EGAF00002307737 cram 5.7 GB
EGAF00002307738 cram 5.2 GB
EGAF00002307739 cram 3.9 GB
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EGAF00002307742 cram 4.1 GB
EGAF00002307743 cram 4.2 GB
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EGAF00002307754 cram 3.3 GB
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EGAF00002307808 cram 3.2 GB
EGAF00002307809 cram 4.2 GB
EGAF00002307810 cram 5.0 GB
EGAF00002307811 cram 4.9 GB
EGAF00002307812 cram 3.4 GB
EGAF00002307813 cram 4.0 GB
EGAF00002307814 cram 4.5 GB
EGAF00002307815 cram 3.7 GB
EGAF00002307816 cram 3.5 GB
EGAF00002307817 cram 4.6 GB
EGAF00002307818 cram 5.4 GB
EGAF00002307819 cram 5.3 GB
EGAF00002307820 cram 3.7 GB
EGAF00002307821 cram 4.4 GB
EGAF00002307822 cram 4.9 GB
EGAF00002307823 cram 4.0 GB
EGAF00002307824 cram 3.5 GB
EGAF00002307825 cram 4.7 GB
EGAF00002307826 cram 5.6 GB
EGAF00002307827 cram 5.4 GB
EGAF00002307828 cram 3.8 GB
EGAF00002307829 cram 4.5 GB
EGAF00002307830 cram 5.0 GB
EGAF00002307831 cram 4.1 GB
EGAF00002307832 cram 3.4 GB
EGAF00002307833 cram 4.5 GB
EGAF00002307834 cram 5.4 GB
EGAF00002307835 cram 5.2 GB
EGAF00002307836 cram 3.6 GB
EGAF00002307837 cram 4.3 GB
EGAF00002307838 cram 4.9 GB
EGAF00002307839 cram 3.9 GB
EGAF00002307840 cram 3.4 GB
EGAF00002307841 cram 4.6 GB
EGAF00002307842 cram 5.4 GB
EGAF00002307843 cram 5.2 GB
EGAF00002307844 cram 3.7 GB
EGAF00002307845 cram 4.3 GB
EGAF00002307846 cram 4.9 GB
EGAF00002307847 cram 4.0 GB
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EGAF00002307849 cram 4.6 GB
EGAF00002307850 cram 5.3 GB
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EGAF00002307854 cram 4.9 GB
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EGAF00002307857 cram 4.4 GB
EGAF00002307858 cram 5.2 GB
EGAF00002307859 cram 5.1 GB
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EGAF00002307862 cram 4.7 GB
EGAF00002307863 cram 3.8 GB
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EGAF00002307866 cram 4.9 GB
EGAF00002307867 cram 4.8 GB
EGAF00002307868 cram 3.4 GB
EGAF00002307869 cram 4.0 GB
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EGAF00002307871 cram 3.6 GB
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EGAF00002307892 cram 6.1 GB
EGAF00002307893 cram 6.5 GB
EGAF00002307894 cram 7.6 GB
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EGAF00002307896 cram 6.1 GB
EGAF00002307897 cram 6.2 GB
EGAF00002307898 cram 6.5 GB
EGAF00002307899 cram 7.6 GB
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EGAF00002307905 cram 4.9 GB
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EGAF00002307910 cram 5.4 GB
EGAF00002307911 cram 5.5 GB
EGAF00002307912 cram 5.3 GB
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EGAF00002307916 cram 5.1 GB
EGAF00002307917 cram 3.7 GB
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EGAF00002307919 cram 5.5 GB
EGAF00002307920 cram 5.4 GB
EGAF00002307923 cram 4.1 GB
EGAF00002307924 cram 5.2 GB
EGAF00002307925 cram 3.9 GB
EGAF00002307926 cram 5.3 GB
EGAF00002307927 cram 5.5 GB
EGAF00002307928 cram 5.3 GB
EGAF00002307929 cram 4.4 GB
EGAF00002307930 cram 6.1 GB
EGAF00002307931 cram 6.2 GB
EGAF00002307932 cram 6.5 GB
EGAF00002307933 cram 7.6 GB
EGAF00002307934 cram 4.4 GB
EGAF00002307935 cram 6.0 GB
EGAF00002307936 cram 6.1 GB
EGAF00002307937 cram 6.5 GB
EGAF00002307938 cram 7.5 GB
EGAF00002307939 cram 4.4 GB
EGAF00002307940 cram 6.0 GB
EGAF00002307941 cram 6.1 GB
EGAF00002307942 cram 6.5 GB
EGAF00002307943 cram 7.5 GB
EGAF00002307944 cram 5.4 GB
EGAF00002307945 cram 5.7 GB
EGAF00002307946 cram 5.1 GB
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EGAF00002307955 cram 4.8 GB
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EGAF00002307957 cram 5.7 GB
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EGAF00002307961 cram 4.8 GB
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EGAF00002307966 cram 5.7 GB
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EGAF00002307971 cram 5.9 GB
EGAF00002307972 cram 6.6 GB
EGAF00002307973 cram 6.6 GB
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EGAF00002307976 cram 5.9 GB
EGAF00002307977 cram 6.7 GB
EGAF00002307978 cram 6.7 GB
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EGAF00002307981 cram 6.0 GB
EGAF00002307982 cram 6.8 GB
EGAF00002307983 cram 6.8 GB
EGAF00002307984 cram 5.7 GB
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EGAF00002307987 cram 7.2 GB
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EGAF00002308011 cram 5.9 GB
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EGAF00002308013 cram 5.7 GB
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EGAF00002308017 cram 4.8 GB
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EGAF00002308019 cram 5.7 GB
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EGAF00002308022 cram 4.9 GB
EGAF00002308023 cram 4.8 GB
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EGAF00002308025 cram 5.7 GB
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EGAF00002308029 cram 4.8 GB
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EGAF00002308031 cram 5.8 GB
EGAF00002308032 cram 6.6 GB
EGAF00002308033 cram 5.7 GB
EGAF00002308034 cram 7.1 GB
EGAF00002308035 cram 5.4 GB
EGAF00002308036 cram 5.6 GB
EGAF00002308037 cram 6.4 GB
EGAF00002308038 cram 5.6 GB
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EGAF00002308041 cram 5.7 GB
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EGAF00002308043 cram 5.6 GB
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EGAF00002308045 cram 5.6 GB
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EGAF00002308047 cram 5.9 GB
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EGAF00002308051 cram 5.9 GB
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EGAF00002308053 cram 6.6 GB
EGAF00002308054 cram 6.7 GB
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EGAF00002308058 cram 6.7 GB
EGAF00002308059 cram 6.7 GB
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EGAF00002308344 cram 5.5 GB
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EGAF00002308363 cram 17.5 GB
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EGAF00002308367 cram 11.4 GB
EGAF00002308368 cram 9.7 GB
EGAF00002308369 cram 12.3 GB
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EGAF00002308371 cram 9.7 GB
EGAF00002308372 cram 12.4 GB
EGAF00002308373 cram 11.5 GB
EGAF00002308374 cram 9.8 GB
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EGAF00002308376 cram 7.0 GB
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EGAF00002308378 cram 6.3 GB
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EGAF00002308408 cram 5.9 GB
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EGAF00002308426 cram 5.7 GB
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EGAF00002308432 cram 5.6 GB
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EGAF00002308438 cram 5.6 GB
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EGAF00002308466 cram 5.6 GB
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EGAF00002308469 cram 5.9 GB
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EGAF00002308471 cram 5.5 GB
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EGAF00002308474 cram 5.9 GB
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EGAF00002308476 cram 5.6 GB
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EGAF00002308479 cram 5.9 GB
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EGAF00002308481 cram 5.8 GB
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EGAF00002308487 cram 6.7 GB
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EGAF00002308489 cram 6.8 GB
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EGAF00002308492 cram 6.7 GB
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EGAF00002308494 cram 6.7 GB
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EGAF00002308497 cram 6.7 GB
EGAF00002308498 cram 7.1 GB
EGAF00002308499 cram 6.7 GB
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EGAF00002308502 cram 8.0 GB
EGAF00002308505 cram 10.0 GB
EGAF00002308506 cram 8.0 GB
EGAF00002308509 cram 10.0 GB
EGAF00002308510 cram 8.0 GB
EGAF00002308513 cram 9.9 GB
EGAF00002308514 cram 8.0 GB
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EGAF00002308517 cram 6.1 GB
EGAF00002308519 cram 8.0 GB
EGAF00002308520 cram 6.5 GB
EGAF00002308521 cram 8.7 GB
EGAF00002308522 cram 2.9 GB
EGAF00002308523 cram 9.5 GB
EGAF00002308524 cram 8.7 GB
EGAF00002308525 cram 7.0 GB
EGAF00002308526 cram 6.7 GB
EGAF00002308554 cram 5.9 GB
EGAF00002308555 cram 4.8 GB
EGAF00002308556 cram 6.1 GB
EGAF00002308560 cram 5.4 GB
EGAF00002308561 cram 5.8 GB
EGAF00002308562 cram 4.7 GB
EGAF00002308563 cram 6.2 GB
EGAF00002308567 cram 5.6 GB
EGAF00002308568 cram 5.9 GB
EGAF00002308569 cram 4.8 GB
EGAF00002308570 cram 6.1 GB
EGAF00002308574 cram 5.4 GB
EGAF00002308575 cram 5.8 GB
EGAF00002308576 cram 4.8 GB
EGAF00002308577 cram 6.0 GB
EGAF00002308581 cram 5.3 GB
EGAF00002308582 cram 5.7 GB
EGAF00002308584 cram 8.8 GB
EGAF00002308585 cram 2.9 GB
EGAF00002308586 cram 9.6 GB
EGAF00002308587 cram 8.8 GB
EGAF00002308589 cram 8.8 GB
EGAF00002308590 cram 2.9 GB
EGAF00002308591 cram 9.5 GB
EGAF00002308592 cram 8.8 GB
EGAF00002308594 cram 8.9 GB
EGAF00002308595 cram 3.0 GB
EGAF00002308596 cram 9.7 GB
EGAF00002308597 cram 9.0 GB
EGAF00002308599 cram 9.0 GB
EGAF00002308600 cram 3.0 GB
EGAF00002308601 cram 9.7 GB
EGAF00002308602 cram 9.0 GB
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EGAF00002308605 cram 6.0 GB
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EGAF00002308611 cram 6.6 GB
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EGAF00002308703 cram 7.7 GB
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EGAF00002308736 cram 6.5 GB
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EGAF00002308741 cram 6.4 GB
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EGAF00002308743 cram 5.4 GB
EGAF00002308745 cram 13.7 GB
EGAF00002308746 cram 6.4 GB
EGAF00002308747 cram 6.0 GB
EGAF00002308748 cram 5.3 GB
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EGAF00002308753 cram 5.3 GB
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EGAF00002308787 cram 5.9 GB
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EGAF00002308793 cram 4.6 GB
EGAF00002308822 cram 19.0 GB
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EGAF00002723867 cram 7.6 GB
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EGAF00002723873 cram 6.9 GB
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EGAF00002723879 cram 6.2 GB
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EGAF00002723881 cram 5.8 GB
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EGAF00002723883 cram 6.8 GB
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EGAF00002723885 cram 5.6 GB
EGAF00002723886 cram 5.9 GB
EGAF00002723887 cram 7.0 GB
EGAF00002723888 cram 6.9 GB
EGAF00002723889 cram 6.2 GB
EGAF00002723890 cram 5.7 GB
EGAF00002723891 cram 5.8 GB
EGAF00002723892 cram 6.9 GB
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EGAF00002723895 cram 8.5 GB
EGAF00002723896 cram 8.2 GB
EGAF00002723897 cram 8.4 GB
EGAF00002723898 cram 8.2 GB
EGAF00002723899 cram 7.9 GB
EGAF00002723900 cram 8.0 GB
EGAF00002723901 cram 8.1 GB
EGAF00002723902 cram 7.8 GB
EGAF00002723903 cram 7.9 GB
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EGAF00002723905 cram 8.0 GB
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EGAF00002869011 cram 11.9 GB
EGAF00002869012 cram 11.3 GB
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EGAF00003247022 cram 7.8 GB
EGAF00003247023 cram 7.3 GB
EGAF00003247024 cram 6.7 GB
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EGAF00003247026 cram 7.7 GB
EGAF00003247027 cram 8.4 GB
EGAF00003247028 cram 7.8 GB
EGAF00003247029 cram 7.2 GB
EGAF00003247030 cram 10.5 GB
EGAF00003247031 cram 9.0 GB
EGAF00003247032 cram 8.7 GB
EGAF00003247033 cram 8.7 GB
EGAF00003247034 cram 10.3 GB
EGAF00003247035 cram 8.8 GB
EGAF00003247036 cram 8.5 GB
EGAF00003247037 cram 8.6 GB
EGAF00003247038 cram 9.6 GB
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EGAF00003247041 cram 7.9 GB
EGAF00003247042 cram 8.8 GB
EGAF00003247043 cram 8.5 GB
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EGAF00003247045 cram 5.8 GB
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EGAF00003605733 cram 9.9 GB
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EGAF00003605736 cram 11.6 GB
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EGAF00004837163 cram 35.8 GB
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EGAF00004837665 cram 4.3 GB
EGAF00004837666 cram 4.9 GB
EGAF00004837667 cram 5.1 GB
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EGAF00004837670 cram 4.4 GB
EGAF00004837671 cram 4.9 GB
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EGAF00004837673 cram 4.4 GB
EGAF00004837674 cram 4.8 GB
EGAF00004837675 cram 5.1 GB
EGAF00004837676 cram 4.8 GB
EGAF00004837677 cram 4.3 GB
EGAF00004837678 cram 4.4 GB
EGAF00004837679 cram 4.8 GB
EGAF00004837680 cram 4.3 GB
EGAF00004837681 cram 4.3 GB
EGAF00004837682 cram 4.7 GB
EGAF00004837683 cram 5.0 GB
EGAF00004837684 cram 4.7 GB
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EGAF00004837686 cram 4.3 GB
EGAF00004837687 cram 4.7 GB
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EGAF00004837689 cram 4.3 GB
EGAF00004837690 cram 4.8 GB
EGAF00004837691 cram 5.0 GB
EGAF00004837692 cram 4.7 GB
EGAF00004837693 cram 4.3 GB
EGAF00004837694 cram 4.3 GB
EGAF00004837695 cram 4.8 GB
EGAF00004837696 cram 4.2 GB
EGAF00004837697 cram 4.3 GB
EGAF00004837698 cram 4.7 GB
EGAF00004837699 cram 5.0 GB
EGAF00004837700 cram 4.7 GB
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EGAF00004837702 cram 4.2 GB
EGAF00004837703 cram 4.7 GB
EGAF00004837704 cram 4.2 GB
EGAF00004837705 cram 4.2 GB
EGAF00004837706 cram 4.6 GB
EGAF00004837707 cram 4.9 GB
EGAF00004837708 cram 4.6 GB
EGAF00004837709 cram 4.1 GB
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EGAF00004837711 cram 4.6 GB
EGAF00004837712 cram 4.1 GB
EGAF00004837713 cram 4.2 GB
EGAF00004837714 cram 4.6 GB
EGAF00004837715 cram 4.4 GB
EGAF00004837716 cram 4.9 GB
EGAF00004837717 cram 4.5 GB
EGAF00004837718 cram 5.0 GB
EGAF00004837719 cram 3.9 GB
EGAF00004837720 cram 4.9 GB
EGAF00004837721 cram 4.8 GB
EGAF00004837722 cram 4.5 GB
EGAF00004837723 cram 4.4 GB
EGAF00004837724 cram 5.0 GB
EGAF00004837725 cram 4.5 GB
EGAF00004837726 cram 5.1 GB
EGAF00004837727 cram 3.8 GB
EGAF00004837728 cram 4.8 GB
EGAF00004837729 cram 4.8 GB
EGAF00004837730 cram 4.6 GB
EGAF00004837731 cram 4.4 GB
EGAF00004837732 cram 5.0 GB
EGAF00004837733 cram 4.5 GB
EGAF00004837734 cram 5.1 GB
EGAF00004837735 cram 3.9 GB
EGAF00004837736 cram 4.9 GB
EGAF00004837737 cram 4.8 GB
EGAF00004837738 cram 4.6 GB
EGAF00004837739 cram 4.4 GB
EGAF00004837740 cram 4.9 GB
EGAF00004837741 cram 4.5 GB
EGAF00004837742 cram 5.1 GB
EGAF00004837743 cram 3.9 GB
EGAF00004837744 cram 4.9 GB
EGAF00004837745 cram 4.8 GB
EGAF00004837746 cram 4.6 GB
EGAF00004837747 cram 4.4 GB
EGAF00004837748 cram 5.0 GB
EGAF00004837749 cram 4.5 GB
EGAF00004837750 cram 5.1 GB
EGAF00004837751 cram 3.9 GB
EGAF00004837752 cram 4.9 GB
EGAF00004837753 cram 4.9 GB
EGAF00004837754 cram 4.6 GB
EGAF00004837755 cram 4.3 GB
EGAF00004837756 cram 4.9 GB
EGAF00004837757 cram 4.4 GB
EGAF00004837758 cram 5.0 GB
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EGAF00004856967 cram 5.5 GB
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EGAF00004856969 cram 5.5 GB
EGAF00004856970 cram 5.8 GB
EGAF00004856971 cram 5.3 GB
EGAF00004856972 cram 5.3 GB
EGAF00004856973 cram 5.3 GB
EGAF00004856974 cram 5.9 GB
EGAF00004856975 cram 5.3 GB
EGAF00004856976 cram 5.6 GB
EGAF00004856977 cram 5.1 GB
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EGAF00004856979 cram 5.2 GB
EGAF00004856980 cram 5.7 GB
EGAF00004856981 cram 5.2 GB
EGAF00004856982 cram 5.5 GB
EGAF00004856983 cram 5.0 GB
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EGAF00004856985 cram 5.2 GB
EGAF00004856986 cram 5.7 GB
EGAF00004856987 cram 5.2 GB
EGAF00004856988 cram 5.5 GB
EGAF00004856989 cram 5.0 GB
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EGAF00004856992 cram 5.8 GB
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