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Integrated Multiomics Uncovers Distinct Macrophage Alterations in Human Metabolic dysfunction-Associated Steatohepatitis Progression

We report single-nuclei RNA sequencing data (n=18) from human livers in metabolic dysfunction-associated steatotic liver disease (MASLD) patients. there are 5 MASH, 4 MASL, 5 control obese and 4 control lean samples.

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Applicability This policy applies to the access to and transfer of VIB research datasets that contain non-anonymous Personal Data which are subject to the provisions of the General Data Protection Regulation (EU) 2016/679. Access/transfer conditions - The access/transfer is subject to approval by the VIB Data Access Committee. - The proposed research purpose should not be incompatible with the primary research purpose for which the data were originally generated. - The Recipient shall have in place adequate safeguards for the protection of Personal Data. - Access is subject to a Data Transfer/Access Agreement which will be managed by VIB Innovation & Business. - The Data Transfer/Access will be limited to the Data that are necessary for the proposed research. Access/transfer procedure - Requests to access or obtain non-anonymous datasets should be submitted to the responsible corresponding author that has uploaded the dataset into the repository, and with a copy to dac@vib.be. - The request should contain the following information: - Name, affiliation (legal entity) and contact information of the requesting recipient party. - Reference to the specific dataset(s) for which access or transfer is requested. - Description of the research purpose for which the data will be used. - The VIB Data Access Committee takes decisions to approve access/transfer within 14 days upon receipt of the request. - Data access will be given / Data will be transferred after completion of the Data Transfer/Access Agreement.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000000768 Transcriptome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF50000275199 fastq.gz 2.9 GB
EGAF50000275200 fastq.gz 8.8 GB
EGAF50000275201 fastq.gz 19.3 GB
EGAF50000275202 fastq.gz 2.1 GB
EGAF50000275203 fastq.gz 7.0 GB
EGAF50000275204 fastq.gz 15.5 GB
EGAF50000275205 fastq.gz 3.4 GB
EGAF50000275206 fastq.gz 10.7 GB
EGAF50000275207 fastq.gz 23.1 GB
EGAF50000275208 fastq.gz 1.7 GB
EGAF50000275209 fastq.gz 5.3 GB
EGAF50000275210 fastq.gz 11.8 GB
EGAF50000275211 fastq.gz 3.2 GB
EGAF50000275212 fastq.gz 10.4 GB
EGAF50000275213 fastq.gz 21.8 GB
EGAF50000275214 fastq.gz 2.6 GB
EGAF50000275215 fastq.gz 8.1 GB
EGAF50000275216 fastq.gz 18.2 GB
EGAF50000275217 fastq.gz 3.2 GB
EGAF50000275218 fastq.gz 23.4 GB
EGAF50000275219 fastq.gz 10.6 GB
EGAF50000275220 fastq.gz 10.8 GB
EGAF50000275221 fastq.gz 3.4 GB
EGAF50000275222 fastq.gz 24.9 GB
EGAF50000275223 fastq.gz 3.1 GB
EGAF50000275224 fastq.gz 10.0 GB
EGAF50000275225 fastq.gz 22.6 GB
EGAF50000275226 fastq.gz 3.3 GB
EGAF50000275227 fastq.gz 10.3 GB
EGAF50000275228 fastq.gz 21.1 GB
EGAF50000275229 fastq.gz 14.1 GB
EGAF50000275230 fastq.gz 2.1 GB
EGAF50000275231 fastq.gz 6.7 GB
EGAF50000275232 fastq.gz 2.5 GB
EGAF50000275233 fastq.gz 7.9 GB
EGAF50000275234 fastq.gz 16.7 GB
EGAF50000275235 fastq.gz 2.4 GB
EGAF50000275236 fastq.gz 7.9 GB
EGAF50000275237 fastq.gz 15.5 GB
EGAF50000275238 fastq.gz 1.7 GB
EGAF50000275239 fastq.gz 5.3 GB
EGAF50000275240 fastq.gz 11.7 GB
EGAF50000275241 fastq.gz 2.6 GB
EGAF50000275242 fastq.gz 8.6 GB
EGAF50000275243 fastq.gz 18.9 GB
EGAF50000275244 fastq.gz 3.2 GB
EGAF50000275245 fastq.gz 10.3 GB
EGAF50000275246 fastq.gz 22.2 GB
EGAF50000275247 fastq.gz 7.6 GB
EGAF50000275248 fastq.gz 15.9 GB
EGAF50000275249 fastq.gz 2.5 GB
EGAF50000275250 fastq.gz 19.4 GB
EGAF50000275251 fastq.gz 2.7 GB
EGAF50000275252 fastq.gz 9.2 GB
54 Files (540.1 GB)