Single-cell genome and transcriptome profiling of high-grade serous ovarian cancer
This dataset contains joint single-cell whole-genome sequencing (scWGS) and mRNA sequencing data generated using DNTR-seq from 4 high-grade serous ovarian cancer samples. Approximately 500 quality-controlled single cells per patient were profiled, with DNA and RNA libraries sequenced separately but derived from the same individual cells. Raw sequencing files are provided in FASTQ format and enable analysis of subclonal copy number alterations, gene dosage effects, and transcriptional heterogeneity.
- 15/06/2026
- 4 samples
- DAC: EGAC00001001760
- Technology: Illumina NovaSeq 6000
DUO:0000007 version: 2019-01-07
disease specific research
This data use permission indicates that use is allowed provided it is related to the specified disease.
ModifiersMONDO:0004992
DUO:0000026 version: 2019-01-07
user specific restriction
This data use modifier indicates that use is limited to use by approved users.
DUO:0000027 version: 2019-01-07
project specific restriction
This data use modifier indicates that use is limited to use within an approved project.
DUO:0000028 version: 2019-01-07
institution specific restriction
This data use modifier indicates that use is limited to use within an approved institution.
The data can only be used for cancer research that is inline with the research areas delineated in the patient consent. These include cancer biomarkers, prognostic factors, mechanisms behind the tumor evolution during treatment and treatment options. The data can also be used for validation of studies published by the contributing consortia (MUPETFaasi2, HERCULES, CHEMORESPONSE).
The data can only be used for cancer research that is inline with the research areas delineated in the patient consent. These include cancer biomarkers, prognostic factors, mechanisms behind the tumor evolution during treatment and treatment options. The data can also be used for validation of studies published by the contributing consortia (MUPETFaasi2, HERCULES, CHEMORESPONSE). See link for full description
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS50000001643 | Transcriptome Sequencing |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
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| EGAF00009001063 | fq.gz | 4.8 GB |
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| EGAF00009001064 | fq.gz | 8.9 GB |
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| EGAF00009001065 | fq.gz | 17.7 GB |
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| EGAF00009001066 | fq.gz | 15.5 GB |
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| EGAF00009001067 | fq.gz | 16.1 GB |
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| EGAF00009001068 | fq.gz | 17.5 GB |
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| EGAF00009001069 | fq.gz | 3.9 GB |
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| EGAF00009001070 | fq.gz | 23.5 GB |
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| EGAF00009001071 | fq.gz | 21.9 GB |
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| EGAF00009001072 | fq.gz | 22.9 GB |
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| EGAF00009001073 | fq.gz | 22.2 GB |
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| EGAF00009001074 | fq.gz | 25.7 GB |
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| EGAF00009001075 | fq.gz | 8.8 GB |
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| EGAF00009001076 | fq.gz | 21.8 GB |
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| EGAF00009001077 | fq.gz | 28.5 GB |
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| EGAF00009001078 | fq.gz | 19.6 GB |
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| 16 Files (279.3 GB) | ||||
