About file location

As the EGA is co-managed by the EMBL-EBI and CRG, files could be located in the UK and/or Spain, as indicated by their respective flags.

Alternatively, files could be located in one of the international Federated EGA nodes, as indicated next to the node's flag.
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Bulk BCR repertoire sequencing from longitudinal dengue challenge samples

This dataset contains bulk BCR/IGH adaptive immune receptor repertoire sequencing data from longitudinal whole-blood RNA samples collected during a controlled primary DENV1 human challenge study. Raw paired-end FASTQ files are provided for available participant-timepoint samples, with associated processed clone-pass repertoire tables generated using the nf-core/airrflow/Immcantation workflow. The dataset includes samples from participants 201-209 across available days 0, 8, 10, 14, and 28, excluding missing participant-timepoints. The data support analysis of BCR clonal expansion, isotype usage, somatic hypermutation, and convergent antibody responses after dengue infection.

Request Access

DUO:0000007
version: 2021-02-23

disease specific research

This data use permission indicates that use is allowed provided it is related to the specified disease.

ModifiersMONDO:0005502 dengue disease

DUO:0000015
version: 2021-02-23

no general methods research

This data use modifier indicates that use does not allow methods development research (e.g., development of software or algorithms).

DUO:0000021
version: 2021-02-23

ethics approval required

This data use modifier indicates that the requestor must provide documentation of local IRB/ERB approval.

DUO:0000027
version: 2021-02-23

project specific restriction

This data use modifier indicates that use is limited to use within an approved project.

DUO:0000028
version: 2021-02-23

institution specific restriction

This data use modifier indicates that use is limited to use within an approved institution.

VLAIO DenMark Project controlled access policy

Access to data from the VLAIO DenMark project “Use of multimodel omics technologies to study Dengue host response markers” is controlled by the VLAIO DenMark Project Data Access Committee. The project is a collaboration between Janssen Pharmaceutica NV, Universiteit Gent, and the Institute of Tropical Medicine Antwerp. Access may be granted to qualified researchers for scientifically justified research use related to dengue infection, host immune response, biomarker discovery, immunological profiling, or related biomedical research. Requests must include a clear research proposal, institutional affiliation, evidence of appropriate ethics approval where applicable, and confirmation that the proposed use is consistent with participant consent and applicable data protection requirements. Approved users must use the data only for the approved research purpose, maintain confidentiality, protect the data using appropriate technical and organisational safeguards, and comply with all applicable laws and institutional policies. Users may not attempt to identify or re-identify participants, may not link the data with other datasets for re-identification purposes, may not redistribute the data to unauthorised third parties, and may not use the data for purposes outside the approved project without renewed DAC approval. Any publication or public communication based on the data must acknowledge the VLAIO DenMark project and the contributing organisations where appropriate, and must not disclose information that could compromise participant privacy or confidentiality. Access may be withdrawn if users breach the approved terms of use.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000001944 Transcriptome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
i
EGAF50000919503 fastq.gz 223.0 MB
EGAF50000919504 fastq.gz 107.3 MB
EGAF50000919505 fastq.gz 166.7 MB
EGAF50000919506 fastq.gz 142.5 MB
EGAF50000919507 fastq.gz 281.6 MB
EGAF50000919508 fastq.gz 391.1 MB
EGAF50000919509 fastq.gz 307.0 MB
EGAF50000919510 fastq.gz 434.9 MB
EGAF50000919511 fastq.gz 222.4 MB
EGAF50000919512 fastq.gz 316.9 MB
EGAF50000919513 fastq.gz 358.8 MB
EGAF50000919514 fastq.gz 542.2 MB
EGAF50000919515 fastq.gz 705.4 MB
EGAF50000919516 fastq.gz 387.4 MB
EGAF50000919517 fastq.gz 525.6 MB
EGAF50000919518 fastq.gz 510.1 MB
EGAF50000919519 fastq.gz 886.7 MB
EGAF50000919520 fastq.gz 649.0 MB
EGAF50000919521 fastq.gz 581.7 MB
EGAF50000919522 fastq.gz 422.7 MB
EGAF50000919523 fastq.gz 875.0 MB
EGAF50000919524 fastq.gz 606.1 MB
EGAF50000919525 fastq.gz 647.2 MB
EGAF50000919526 fastq.gz 465.9 MB
EGAF50000919527 fastq.gz 133.2 MB
EGAF50000919528 fastq.gz 193.2 MB
EGAF50000919529 fastq.gz 112.0 MB
EGAF50000919530 fastq.gz 166.0 MB
EGAF50000919531 fastq.gz 166.6 MB
EGAF50000919532 fastq.gz 287.0 MB
EGAF50000919533 fastq.gz 419.2 MB
EGAF50000919534 fastq.gz 116.1 MB
EGAF50000919535 fastq.gz 164.9 MB
EGAF50000919536 fastq.gz 273.9 MB
EGAF50000919537 fastq.gz 245.6 MB
EGAF50000919538 fastq.gz 442.1 MB
EGAF50000919539 fastq.gz 95.8 MB
EGAF50000919540 fastq.gz 141.9 MB
EGAF50000919541 fastq.gz 141.5 MB
EGAF50000919542 fastq.gz 210.7 MB
EGAF50000919543 fastq.gz 150.7 MB
EGAF50000919544 fastq.gz 219.0 MB
EGAF50000919545 fastq.gz 240.9 MB
EGAF50000919546 fastq.gz 157.8 MB
EGAF50000919547 fastq.gz 155.0 MB
EGAF50000919548 fastq.gz 233.0 MB
EGAF50000919549 fastq.gz 174.0 MB
EGAF50000919550 fastq.gz 269.2 MB
EGAF50000919551 fastq.gz 123.7 MB
EGAF50000919552 fastq.gz 197.2 MB
EGAF50000919553 fastq.gz 153.9 MB
EGAF50000919554 fastq.gz 249.5 MB
EGAF50000919555 fastq.gz 108.5 MB
EGAF50000919556 fastq.gz 167.4 MB
EGAF50000919557 fastq.gz 220.9 MB
EGAF50000919558 fastq.gz 349.6 MB
EGAF50000919559 fastq.gz 114.3 MB
EGAF50000919560 fastq.gz 165.4 MB
EGAF50000919561 fastq.gz 141.7 MB
EGAF50000919562 fastq.gz 211.1 MB
EGAF50000919563 fastq.gz 88.6 MB
EGAF50000919564 fastq.gz 143.1 MB
EGAF50000919565 fastq.gz 123.9 MB
EGAF50000919566 fastq.gz 184.3 MB
EGAF50000919567 fastq.gz 147.8 MB
EGAF50000919568 fastq.gz 220.2 MB
EGAF50000919569 fastq.gz 189.2 MB
EGAF50000919570 fastq.gz 307.5 MB
EGAF50000919571 fastq.gz 96.5 MB
EGAF50000919572 fastq.gz 144.0 MB
EGAF50000919573 fastq.gz 132.5 MB
EGAF50000919574 fastq.gz 207.6 MB
EGAF50000919575 fastq.gz 89.6 MB
EGAF50000919576 fastq.gz 135.2 MB
EGAF50000919577 fastq.gz 116.6 MB
EGAF50000919578 fastq.gz 184.6 MB
EGAF50000919579 fastq.gz 146.7 MB
EGAF50000919580 fastq.gz 124.7 MB
EGAF50000919581 fastq.gz 186.8 MB
EGAF50000919582 fastq.gz 102.1 MB
EGAF50000919583 fastq.gz 90.8 MB
EGAF50000919584 fastq.gz 136.8 MB
EGAF50000919585 fastq.gz 114.8 MB
EGAF50000919586 fastq.gz 194.3 MB
EGAF50000919587 fastq.gz 222.5 MB
EGAF50000919588 fastq.gz 323.5 MB
EGAF50000919589 fastq.gz 324.8 MB
EGAF50000919590 fastq.gz 495.0 MB
EGAF50000919591 fastq.gz 185.0 MB
EGAF50000919592 fastq.gz 267.3 MB
EGAF50000919593 fastq.gz 230.4 MB
EGAF50000919594 fastq.gz 333.8 MB
EGAF50000919595 fastq.gz 169.0 MB
EGAF50000919596 fastq.gz 245.7 MB
EGAF50000919597 fastq.gz 217.8 MB
EGAF50000919598 fastq.gz 316.4 MB
EGAF50000919599 fastq.gz 167.6 MB
EGAF50000919600 fastq.gz 239.9 MB
EGAF50000919601 fastq.gz 230.5 MB
EGAF50000919602 fastq.gz 303.9 MB
EGAF50000919603 fastq.gz 165.7 MB
EGAF50000919604 fastq.gz 238.2 MB
EGAF50000919605 fastq.gz 246.7 MB
EGAF50000919606 fastq.gz 360.0 MB
EGAF50000919607 fastq.gz 181.9 MB
EGAF50000919608 fastq.gz 265.5 MB
EGAF50000919609 fastq.gz 279.1 MB
EGAF50000919610 fastq.gz 415.5 MB
EGAF50000919611 fastq.gz 266.7 MB
EGAF50000919612 fastq.gz 393.2 MB
EGAF50000919613 fastq.gz 192.4 MB
EGAF50000919614 fastq.gz 284.7 MB
EGAF50000919615 fastq.gz 151.5 MB
EGAF50000919616 fastq.gz 215.7 MB
EGAF50000919617 fastq.gz 238.2 MB
EGAF50000919618 fastq.gz 353.7 MB
EGAF50000919619 fastq.gz 135.9 MB
EGAF50000919620 fastq.gz 205.4 MB
EGAF50000919621 fastq.gz 344.5 MB
EGAF50000919622 fastq.gz 517.7 MB
EGAF50000919623 fastq.gz 225.6 MB
EGAF50000919624 fastq.gz 338.6 MB
EGAF50000919625 fastq.gz 281.0 MB
EGAF50000919626 fastq.gz 431.6 MB
EGAF50000919627 fastq.gz 81.8 MB
EGAF50000919628 fastq.gz 120.1 MB
EGAF50000919629 fastq.gz 103.0 MB
EGAF50000919630 fastq.gz 159.8 MB
EGAF50000919631 fastq.gz 92.2 MB
EGAF50000919632 fastq.gz 135.7 MB
EGAF50000919633 fastq.gz 117.7 MB
EGAF50000919634 fastq.gz 190.5 MB
EGAF50000919635 fastq.gz 98.2 MB
EGAF50000919636 fastq.gz 152.2 MB
EGAF50000919637 fastq.gz 135.1 MB
EGAF50000919638 fastq.gz 202.0 MB
EGAF50000919639 fastq.gz 107.8 MB
EGAF50000919640 fastq.gz 164.3 MB
EGAF50000919641 fastq.gz 249.3 MB
EGAF50000919642 fastq.gz 151.2 MB
EGAF50000919643 fastq.gz 529.9 MB
EGAF50000919644 fastq.gz 721.1 MB
EGAF50000919645 fastq.gz 806.4 MB
EGAF50000919646 fastq.gz 1.2 GB
EGAF50000919647 fastq.gz 486.9 MB
EGAF50000919648 fastq.gz 688.6 MB
EGAF50000919649 fastq.gz 609.8 MB
EGAF50000919650 fastq.gz 938.9 MB
EGAF50000919651 fastq.gz 400.9 MB
EGAF50000919652 fastq.gz 550.6 MB
EGAF50000919653 fastq.gz 529.6 MB
EGAF50000919654 fastq.gz 792.7 MB
EGAF50000919655 fastq.gz 391.3 MB
EGAF50000919656 fastq.gz 538.9 MB
EGAF50000919657 fastq.gz 537.8 MB
EGAF50000919658 fastq.gz 698.8 MB
EGAF50000919659 fastq.gz 667.4 MB
EGAF50000919660 fastq.gz 481.4 MB
EGAF50000919661 fastq.gz 549.5 MB
EGAF50000919662 fastq.gz 389.6 MB
EGAF50000919663 fastq.gz 168.9 MB
EGAF50000919664 fastq.gz 229.4 MB
EGAF50000919665 fastq.gz 217.9 MB
EGAF50000919666 fastq.gz 302.5 MB
EGAF50000919667 fastq.gz 207.7 MB
EGAF50000919668 fastq.gz 286.5 MB
EGAF50000919669 fastq.gz 216.5 MB
EGAF50000919670 fastq.gz 296.1 MB
EGAF50000919671 fastq.gz 214.3 MB
EGAF50000919672 fastq.gz 291.4 MB
EGAF50000919673 fastq.gz 290.8 MB
EGAF50000919674 fastq.gz 395.0 MB
EGAF50000919675 tsv 263.7 MB
EGAF50000919676 tsv 393.3 MB
EGAF50000919677 tsv 587.2 MB
EGAF50000919678 tsv 359.9 MB
EGAF50000919679 tsv 242.1 MB
EGAF50000919680 tsv 261.1 MB
EGAF50000919681 tsv 396.3 MB
EGAF50000919682 tsv 298.2 MB
EGAF50000919683 tsv 445.0 MB
181 Files (53.6 GB)