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Assembled bulk TCR repertoires from longitudinal dengue challenge samples

This dataset contains assembled bulk TCR adaptive immune receptor repertoires from longitudinal whole-blood RNA samples collected during a controlled primary DENV3 human challenge study. The data support analysis of TCR clonal expansion, and convergent receptor responses after dengue infection.

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DUO:0000007
version: 2021-02-23

disease specific research

This data use permission indicates that use is allowed provided it is related to the specified disease.

ModifiersMONDO:0005502 dengue disease

DUO:0000015
version: 2021-02-23

no general methods research

This data use modifier indicates that use does not allow methods development research (e.g., development of software or algorithms).

DUO:0000021
version: 2021-02-23

ethics approval required

This data use modifier indicates that the requestor must provide documentation of local IRB/ERB approval.

DUO:0000027
version: 2021-02-23

project specific restriction

This data use modifier indicates that use is limited to use within an approved project.

DUO:0000028
version: 2021-02-23

institution specific restriction

This data use modifier indicates that use is limited to use within an approved institution.

VLAIO DenMark Project controlled access policy

Access to data from the VLAIO DenMark project “Use of multimodel omics technologies to study Dengue host response markers” is controlled by the VLAIO DenMark Project Data Access Committee. The project is a collaboration between Janssen Pharmaceutica NV, Universiteit Gent, and the Institute of Tropical Medicine Antwerp. Access may be granted to qualified researchers for scientifically justified research use related to dengue infection, host immune response, biomarker discovery, immunological profiling, or related biomedical research. Requests must include a clear research proposal, institutional affiliation, evidence of appropriate ethics approval where applicable, and confirmation that the proposed use is consistent with participant consent and applicable data protection requirements. Approved users must use the data only for the approved research purpose, maintain confidentiality, protect the data using appropriate technical and organisational safeguards, and comply with all applicable laws and institutional policies. Users may not attempt to identify or re-identify participants, may not link the data with other datasets for re-identification purposes, may not redistribute the data to unauthorised third parties, and may not use the data for purposes outside the approved project without renewed DAC approval. Any publication or public communication based on the data must acknowledge the VLAIO DenMark project and the contributing organisations where appropriate, and must not disclose information that could compromise participant privacy or confidentiality. Access may be withdrawn if users breach the approved terms of use.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000002195 Transcriptome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF50001048535 tsv 1.1 GB
EGAF50001048536 tsv 746.6 MB
EGAF50001048537 tsv 1.6 GB
EGAF50001048538 tsv 792.2 MB
EGAF50001048539 tsv 1.1 GB
EGAF50001048540 tsv 1.9 GB
EGAF50001048541 tsv 1.5 GB
EGAF50001048542 tsv 876.8 MB
EGAF50001048543 tsv 1.6 GB
EGAF50001048544 tsv 1.4 GB
EGAF50001048545 tsv 2.5 GB
EGAF50001048546 tsv 723.7 MB
EGAF50001048547 tsv 1.1 GB
EGAF50001048548 tsv 657.1 MB
EGAF50001048549 tsv 448.7 MB
EGAF50001048550 tsv 1.2 GB
EGAF50001048551 tsv 905.3 MB
EGAF50001048552 tsv 987.7 MB
EGAF50001048553 tsv 1.9 GB
EGAF50001048554 tsv 1.4 GB
EGAF50001048555 tsv 1.1 GB
EGAF50001048556 tsv 777.5 MB
EGAF50001048557 tsv 943.1 MB
23 Files (27.2 GB)