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Assembled bulk BCR repertoires from longitudinal dengue challenge samples

This dataset contains assembled bulk BCR/IGH adaptive immune receptor repertoires from longitudinal whole-blood RNA samples collected during a controlled primary DENV3 human challenge study. The data support analysis of BCR clonal expansion, isotype usage, somatic hypermutation, and convergent antibody responses after dengue infection.

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DUO:0000007
version: 2021-02-23

disease specific research

This data use permission indicates that use is allowed provided it is related to the specified disease.

ModifiersMONDO:0005502 dengue disease

DUO:0000015
version: 2021-02-23

no general methods research

This data use modifier indicates that use does not allow methods development research (e.g., development of software or algorithms).

DUO:0000021
version: 2021-02-23

ethics approval required

This data use modifier indicates that the requestor must provide documentation of local IRB/ERB approval.

DUO:0000027
version: 2021-02-23

project specific restriction

This data use modifier indicates that use is limited to use within an approved project.

DUO:0000028
version: 2021-02-23

institution specific restriction

This data use modifier indicates that use is limited to use within an approved institution.

VLAIO DenMark Project controlled access policy

Access to data from the VLAIO DenMark project “Use of multimodel omics technologies to study Dengue host response markers” is controlled by the VLAIO DenMark Project Data Access Committee. The project is a collaboration between Janssen Pharmaceutica NV, Universiteit Gent, and the Institute of Tropical Medicine Antwerp. Access may be granted to qualified researchers for scientifically justified research use related to dengue infection, host immune response, biomarker discovery, immunological profiling, or related biomedical research. Requests must include a clear research proposal, institutional affiliation, evidence of appropriate ethics approval where applicable, and confirmation that the proposed use is consistent with participant consent and applicable data protection requirements. Approved users must use the data only for the approved research purpose, maintain confidentiality, protect the data using appropriate technical and organisational safeguards, and comply with all applicable laws and institutional policies. Users may not attempt to identify or re-identify participants, may not link the data with other datasets for re-identification purposes, may not redistribute the data to unauthorised third parties, and may not use the data for purposes outside the approved project without renewed DAC approval. Any publication or public communication based on the data must acknowledge the VLAIO DenMark project and the contributing organisations where appropriate, and must not disclose information that could compromise participant privacy or confidentiality. Access may be withdrawn if users breach the approved terms of use.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000002195 Transcriptome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF50001048513 tsv 209.3 MB
EGAF50001048514 tsv 420.2 MB
EGAF50001048515 tsv 245.7 MB
EGAF50001048516 tsv 161.7 MB
EGAF50001048517 tsv 326.4 MB
EGAF50001048518 tsv 270.9 MB
EGAF50001048519 tsv 520.2 MB
EGAF50001048520 tsv 127.5 MB
EGAF50001048521 tsv 531.7 MB
EGAF50001048522 tsv 237.8 MB
EGAF50001048523 tsv 510.1 MB
EGAF50001048524 tsv 399.7 MB
EGAF50001048525 tsv 122.4 MB
EGAF50001048526 tsv 256.7 MB
EGAF50001048527 tsv 141.9 MB
EGAF50001048528 tsv 455.4 MB
EGAF50001048529 tsv 271.9 MB
EGAF50001048530 tsv 365.8 MB
EGAF50001048531 tsv 324.0 MB
EGAF50001048532 tsv 575.3 MB
EGAF50001048533 tsv 885.6 MB
EGAF50001048534 tsv 1.1 GB
EGAF50001048558 tsv 624.1 MB
23 Files (9.1 GB)