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• Breast_Heterogeneity_Validation

  Validation of subs and indels called in breast whole genome studies

  Study EGAS00001001972

• Circulating tumor DNA, pathological and immunologic responses to neoadjuvant nivolumab or nivolumab plus relatlimab and chemoradiotherapy in resectable esophageal/gastroesophageal junction cancer

  Study EGAS00001007299

• Nasal brushes analysis

  scRNA-seq samples from healthy and asthma donors part 1.

  Study EGAS00001006657

• A5_SDHB_PCPG_Methylation

  Illumina Infinium MethylationEPIC Array profiling of 93 pheochromocytoma and paraganglioma tumours with and a germline SDHB mutation

  Dataset EGAD00010002667

• Gene expression analysis of clear cell renal cell carcinoma

  To identify genes that are differentially expressed across different conditions (cancer vs normal, normoxic vs hypoxic), we performed RNA-seq in 3 ccRCC cell lines (786-O, A498, UMRC-2), and 1 normal kidney epithelium cell line (HK-2), cultured under normoxic (20% O2) and hypoxic (0.05% O2) conditions.

  Study EGAS50000001324

• Tracing early predictors of glioma evolution under therapy

  Clonal evolution drives cancer progression and therapeutic resistance. Recent studies revealed divergent longitudinal trajectories in gliomas, but early molecular traits steering post-treatment cancer evolution remain unclear. We analyzed sequencing data of 544 initial-recurrent adult diffuse glioma pairs to identify genomic and transcriptomic early predictors of tumor evolution in each molecular subtype.

  Study EGAS00001006894

• PhIP-seq of Japanese patients with SLE

  Bacteriophage Immunoprecipitation Sequencing (PhIP-Seq) datasets of three eHHV-6B-positive SLE patients (three technical replicates), six eHHV-6B-negative SLE patients (three technical replicates), and a negative control lacking sera or plasma (12 technical replicates; Illumina NextSeq) and sequencing data of HHV-6 peptide phage library (two technical replicates; Illumina NextSeq).

  Study EGAS00001007955

• RNA sequencing of CD8 T cells from melanoma patients prior to and during checkpoint immunotherapy and untreated healthy controls

  We are interested in inter-individual variation in transcriptional response to immune checkpoint blockade. We have analysed poly A purified RNA expression from CD8 T cells (297 transcriptomes in total) isolated from metastatic melanoma patients (n=106) prior to and during treatment with either single agent (Pembrolizumab) or combination (Ipilimumab/ Nivolumab) immune checkpoint blockade. We compare expression at different stages of treatment and additionally contrast this with that from healthy controls (n=68).

  Dataset EGAD00001005973

• Department of Pediatrics, The University of Tokyo, PPB Data Access Committee

  Dac EGAC00001000163

• The Ingham Institute Gastro-Intestinal Viral Oncology Group Genome Data Access Committee

  Dac EGAC00001000367

• DAC of the BRITROC project

  Dac EGAC00001000388

• The Danish Reference Genome - GenomeDenmark data access committee

  Dac EGAC00001000562

• MeDIP-seq data in the Peri/postnatal Epigenetics Twins Study (PETS)

  Dac EGAC00001000596

• Data Access Commitee of The First Affiliated Hospital of Nanjing Medical University

  Dac EGAC00001001209

• The Lothian Birth Cohorts Data Access Committee

  Dac EGAC00001001376

• The Egyptian Collaborative Cardiac Genomics Project Data Access Committee (ECCO-GEN DAC)

  Dac EGAC00001001594

• The Egyptian Collaborative Cardiac Genomics Project Data Access Committee (ECCO-GEN DAC)

  Dac EGAC00001001680

• Data Access Committee of the Department of Molecular Neurology, UKEr

  Dac EGAC00001002695

• TULIPs decorate the three-dimensional genome of PFA ependymoma

  Study EGAS00001005476

• The effects of inhaled corticosteroids on healthy airways

  Study EGAS00001007538

• A critical spotlight on the paradigms of FFPE-DNA sequencing

  Study EGAS00001005757

• DNA methylation profiles of samples included in the EORTC 26091 TAVAREC trial

  Study EGAS00001006015

• Measuring the Efficiency of Purging by Nonrandom Mating in Human Populations

  Study EGAS00001007831

• CeD_meta_analysis

  Results of the celiac diease meta-analysis

  Dataset EGAD00010001770

• CeD_Argentina_1

  Association results from the Agentinian cohort one

  Dataset EGAD00010001768

• EGAD00000000060

  Samples from the UK Glomerulonephritis DNA bank

  Dataset EGAD00000000060

• Integrated Genomic and Transcriptomic Analysis Reveals Unique Characteristics of Hepatic Metastases and Pro-metastatic Role of Complement C1q in Pancreatic Ductal Adenocarcinoma

  Study EGAS00001004821

• Genotype of C3 SNPs in LOTx donors and recipients

  Genotype of C3 SNPs in 140 LOTx donors and recipients pairs.

  Dataset EGAD00001006889

• WTCCC2 project controls - 1958 British Birth Cohort and National Blood Service

  WTCCC2 project controls - 1958 British Birth Cohort and National Blood Service

  Study EGAS00000000028

• bulk mRNA-seq of iGRAN (CD14neg) cells from CMML patients and healthy donors

  bulk mRNA-seq of iGRAN (CD14neg) cells from CMML patients and healthy donors [Publication title] CXCL8 secreted by immature granulocytes inhibits wildtype hematopoiesis in chronic myelomonocytic leukemia

  Study EGAS50000000555

• Whole-Exome Sequences Algerian Imazighen and non-Imazighen

  Dataset with 150 whole-exome sequences from Algerian Amazigh (Chaoui and Mozabite) and non-Amazgih saples.

  Dataset EGAD00001010846

• Double/triple hit lymphoma whole exome and panel sequencing data

  Mutational landscape of high-grade B-cell lymphoma with MYC-, BCL2 and/or BCL6 rearrangements characterized by whole-exome sequencing and panel sequencing.

  Dataset EGAD00001007805

• Single-cell transcriptome of human fetal pancreas and in vitro pancreatic spheroids

  This dataset combines single cell transcriptome data from fetal pancreas at 7-10 wpc, embryonic stem cell-derived pancreas progenitors and spheroids generated from both fetal pancreas and human pluripotent stem cell-derived pancreas progenitors.

  Dataset EGAD00001007506

• RNA-seq of Bone Metastasis from breast and prostate cancers

  RNA-seq of Bone Metastasis from breast and prostate cancer (4 breast and 5 prostate samples). Dataset contains BAM files from RNA-seq performed using Illumina HiSeq 2500.

  Dataset EGAD00001006356

• Whole exome sequencing of FFPE material from 41 pediatric BCP-LBL patients.

  This study contain the results of whole exome sequencing analyses of FFPE material from 41 pediatric B-cell precursor lymphoblastic lymphoma patients. Samples were sequenced with a target coverage of 200x. Data are provided as Fastq files.

  Study EGAS50000000290

• TBA

  Analysis of mutational signatures arising in vivo in humans. iPS cells from control patients and100 patients carrying known mutations in DNA repair/editing genes will be generated, andsequenced.Blood from the patients will also be used to generate reference 'germline' sequence data.

  Study EGAS00001000802

• TBA

  Analysis of mutational signatures arising in vivo in humans. iPS cells from control patients and100 patients carrying known mutations in DNA repair/editing genes will be generated, andsequenced.Blood from the patients will also be used to generate reference 'germline' sequence data.

  Study EGAS00001000803

• TBA

  Analysis of mutational signatures arising in vivo in humans. iPS cells from control patients and100 patients carrying known mutations in DNA repair/editing genes will be generated, andsequenced.Blood from the patients will also be used to generate reference 'germline' sequence data.

  Study EGAS00001000801

• RNA-sequencing of T-cell Acute Lymphoblastic Leukemia (T-ALL)

  This dataset contains raw fastq files from the RNA-Seq of 96 T-Acute Lymphoblastic Leukemia. Libraries where prepared using Agilent SureSelect XT-HS2 RNA Reagent Kit. As such, reads contain molecular barcodes that could be specifically handled using the AGeNT tool.

  Dataset EGAD00001010273

• TRACERx NSCLC - Multiregion RNA sequencing data from the 421 cohort

  RNAseq data from the TRACERx 421 cohort

  Dataset EGAD00001009862

• CM214 - Biomarker Analysis From the Phase 3 CheckMate 214 Trial of Nivolumab Plus Ipilimumab (N+I) or Sunitinib (S) in Advanced Renal Cell Carcinoma (aRCC)

  CM214 - Biomarker Analysis From the Phase 3 CheckMate 214 Trial of Nivolumab Plus Ipilimumab (N+I) or Sunitinib (S) in Advanced Renal Cell Carcinoma (aRCC)

  Dataset EGAD00001007938

• He et al. WES data

  This dataset are the bam files of WES data from the paper by He et al.

  Dataset EGAD00001007134

• Genomic Features of Lung Adenocarcinoma from Individuals with <= 10 Pack-Year Smoking History

  Actionable oncogenic alterations are identified in a subset of lung adenocarcinomas. Many of these driver alterations are enriched in lung adenocarcinomas from individuals with minimal smoking history and are generally mutually exclusive of one another. We generated whole-exome and RNA-seq data from lung adenocarcinomas obtained from individuals with &#8804;10 pack-year smoking history. Most of these tumors harbored an established oncogenic alteration. We identified a novel OCLN-RASGRF1 fusion from one tumor that lacked a known oncogenic driver. Functional studies demonstrated this fusion activates RAS signaling and promotes tumorigenesis in cell models.

  Study phs002556

• SJCRH pediatric HGG sequencing data

  A DAC to manage access to sequencing data derived from primary patient tumors and associated models, e.g. xenografts and cell lines.

  Dac EGAC50000000101

• COVID-19 progression and convalescence in common variable immunodeficiency patients

  Longitudinal analysis of single-cell RNAseq datasets of PBMCs from COVID-19 CVID patients and controls.

  Dac EGAC50000000245

• EGAS00001006863

  Targeted DNA-sequencing, whole genome sequencing and whole transcriptome sequencing data on childhood leukaemia patients enrolled on to UK clinical trials (specifically UKALL2003 and UKALL2011).

  Dac EGAC50000000342

• Somatic_mutation_in_edited_cholangiocyte_organoids_WGS

  Characterisation of mutation rates and patterns in edited human cholangiocyte organoids (WGS)

  Study EGAS00001006326

• Chugai_colorectal_organoid_sequencing

  Genomic and transcriptomic characterization of drug-resistant colon cancer stem cell lines.

  Study EGAS00001000872

• Transcriptomic profiling of lymphedema

  RNA-seq of skin from human subjects with and without lymphedema

  Study EGAS00001004516

• RHD_SA_HC24_Cases

  Definite and borderline rheumatic heart disease cases and patients with mild non-diagnostic valvulopathy recruited in Samoa

  Dataset EGAD00010000960