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• Summary statistics for cervical cancer GWAS

  Summary statistics from GWAS meta-analysis of cervical cancer

  Dataset EGAD00001004361

• Liquid biopsy for molecular characterization of diffuse large B-cell lymphoma and early assessment of minimal residual disease

  Circulating tumor DNA (ctDNA) allows genotyping and minimal residual disease (MRD) detection in lymphomas. Using a NGS approach (Euroclonality-NDC), we evaluated clinical and prognostic value of ctDNA in a series of R-CHOP-treated DLBCL patients at baseline (n=68) and after 2-cycles (n=59), monitored by metabolic imaging (PET/CT). A molecular marker was identified in 61/68 (90%) ctDNA samples at diagnosis. Pre-treatment high ctDNA levels significantly correlated with elevated LDH, advanced stage, high risk IPI and a trend to shorter 2-year PFS. Valuable NGS data after 2-cycles of treatment were obtained in 44 cases, and 38 achieved major molecular response (MMR; 2.5-log drop in ctDNA). PFS curves displayed statistically significant differences among those achieving MMR vs. those not achieving MMR (2yr PFS of 76% vs. 0%, p<0.001). Similarly, more than 66% reduction in SUVmax by PET/CT identified two subgroups with different prognosis (2yr PFS of 83% vs. 38%; p<0.001). Combining both approaches MMR and SUVmax reduction, a better stratification was observed (2yr PFS of 84% vs. 17% vs. 0%, p<0.001). Euroclonality-NDC panel allows the detection of a molecular marker in the ctDNA in 90% of DLBCL. ctDNA reduction at 2 cycles and its combination with interim PET results improves patient prognosis stratification.

  Study EGAS50000000215

• Data access agreement for ATRT

  Dac EGAC00001000306

• DAC for BCP-LBL Kiel

  Whole exome sequencing and RNA sequencing of B-Cell Precursor Lymphoblastic Lymphoma tissue biopsies.

  Dac EGAC50000000181

• Human embryo ATAC+RNA single cell sequencing samples DAC (Linnarsson)

  DAC for human embryo ATAC+RNA single cell sequencing samples

  Dac EGAC50000000657

• GenomeWideData_for_Present_Day_Peruvian_individuals_living_in_urban_areas

  Genome-wide data for 432 Admixed individuals from Peru

  Dataset EGAD00010002795

• SAFIR02_Agilent

  Genomics to select patients with metastatic breast cancer for targeted therapy (microarray_agilent)

  Dataset EGAD00010002243

• B99

  Cardio-Metabochip genotypes for B99 cohort

  Dataset EGAD00010001427

• IHIT

  Cardio-Metabochip genotypes for IHIT cohort

  Dataset EGAD00010001428

• EGAD00010000536

  21 unlinked autosomal microsatellite loci for 30 Central Asian populations

  Dataset EGAD00010000536

• WES for Verhaak GBM

  Dataset EGAD00001001109

• WES for verhaak-GBM

  Dataset EGAD00001001110

• Variant_files_100_ID_trios

  High Quality Variant Call files, generated by bioscope, converted to vcf format. Complete dataset for all 300 samples.

  Dataset EGAD00001000277

• Complete Genomics dataset for study EGAS00001002275.

  TBD

  Dataset EGAD00001003187

• ICGC_Pedbrain_WGBS_Pilocytic_Astrocytoma

  18 WGBS lanes for 9 samples of pilocytic astrocytoma.

  Dataset EGAD00001005504

• Aggregated count table

  RNA-seq count matrix for 296 bulk pre-treatment tumors from IMblaze370

  Dataset EGAD00001008552

• Ludwig Center for Cancer Genetics and Therapeutics at Johns Hopkins

  Dac EGAC00001000507

• Data Access Commitee for Dietrich and Wendisch et al., SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis (Submitted)

  Dac EGAC00001001884

• Data Access Commitee for Dietrich and Wendisch et al., SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis (Submitted)

  Dac EGAC00001002335

• OICR-DAC, Ontario Institute for Cancer Research

  Dac EGAC00001000591

• OICR-DAC, Ontario Institute for Cancer Research

  Dac EGAC00001000710

• Liquid biopsy-based minimal residual disease monitoring for early risk stratification and decision-making in advanced non-small cell lung cancer

  Dac EGAC50000000832

• WES for cell lines UWB1.289 and COV362

  exon 11 mutated UWB1.289 and COV362 cell lines

  Dataset EGAD50000000189

• Genotype_HSM1_HSM2

  Genotypes for 2 human skeletal muscle samples

  Dataset EGAD00010002248

• DNA methylation for EGAS00001003603

  Genome-wide DNA methylation profiling of Waldenstrom's macroglobulinemia (WM) patient samples

  Dataset EGAD00010001861