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• The molecular landscape of colorectal cancer reveals genetic mutations.

  We performed whole-exome sequencing of tumor samples and adjacent normal mucosae from 46 patients to characterize the genetic alterations in China.

  Study EGAS00001001893

• ImmunoAgeing_Colonies

  Using patterns of shared mutations between haematopoietic stem cells in 14 individuals with clonal haematpoiesis, we aim to determine the timing of somatic mutation acquisition.

  Study EGAS00001003933

• The molecular landscape of colorectal cancer （17 cases）

  We performed whole-exome sequencing of tumor samples and adjacent normal mucosae from 17 cases to characterize the genetic alterations in china.

  Study EGAS00001002174

• Osteosarcoma_RNAseq

  We propose to definitively characterise the somatic genetics of Osteosarcoma cancer through generation of comprehensive catalogues of somatic mutations by high coverage genome and transcriptome sequencing.

  Study EGAS00001000615

• Lung_Cancer_Whole_Genomes

  We propose to definitively characterise the somatic genetics of Lung cancer through generation of comprehensive catalogues of somatic mutations by high coverage genome sequencing.

  Study EGAS00001000148

• The molecular landscape of colorectal cancer （5 cases）

  We performed whole-exome sequencing of tumor samples and adjacent normal mucosae from 5 patients to characterize the genetic alterations in china.

  Study EGAS00001002374

• Fungal infection in neural tissue from Amyotrophic Lateral Sclerosis

  The study shows that fungus infection, isolated from neural tissue, can be a risk factor to develop Amyothophic lateral sclerosis (ALS).

  Study EGAS00001002473

• BS-seq in plasma of CRC patients

  We performed whole genome bisulfite sequencing of plasma DNA in 11 colorectal cancer patients to study the colonic DNA in plasma.

  Study EGAS00001003117

• Microdissection_sequencing_of_normal_human_prostate

  Histology sections from pathologically benign human prostates were prepared and microdissections retrieved from Laser-Capture Microdissection are submitted to low-input whole-genome sequencing.

  Study EGAS00001003049

• DNA-seq from plasma of 14 liver transplantation patients

  We performed DNA sequencing on the plasma of 14 liver transplantation patients to study the liver DNA in the plasma.

  Study EGAS00001003116

• GEL_WGS_Comparison

  These samples are to be analysed with the CGP Developed cancer panel and the results will be compared with WGS data from 4 different comercial providers.

  Study EGAS00001000649

• Benchmarking DIA-type Proteomics Using Large-Scale Inter-Patient Heterogeneity Dataset

  Benchmarking Proteomics Quantitation in DIA-type data using real patient material to create a benchmark dataset comprising inter-patient heterogeneity

  Study EGAS00001005589

• WGS_of_AML_during_PARPi_therapy

  We will require WGS on Illumina X10 machines of three samples, along with storage and computational power to perform the relevant analysis.

  Study EGAS00001002274

• Epigenomic data of Human muscle stem cell

  To profile the epigenomic landscape of Human muscle stem cell, ChIP-seq of histone marks , WGBS and RNA-seq data were generated.

  Study EGAS00001006159

• The genomic landscape of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

  Use single cell whole genome sequencing data from one iAMP21 patient SJBALL021901 to study the clonal evolution of iAMP21.

  Study EGAS00001006796

• Epigenome-wide association study of cocaine use disorder in postmortem human brain tissue

  We aimed to identify cocaine use disorder associated DNA methylation alterations in the Brodmann Area 9 brain region.

  Study EGAS00001006826

• Rucaparib in patients presenting a metastatic breast cancer

  Whole genome sequencing was performed on 24 patients (tumor DNA paired to constitutional DNA). WGS libraries were subjected to paired-end (2 x 100 bp) sequencing on NovaSeq (Illumina). The 96 files are in FASTQ format.

  Dataset EGAD00001006458

• Single-cell mRNA-sequencing to generate a transcriptomic atlas of RMS

  Single-cell mRNA-sequencing to generate a transcriptomic atlas of soft tissue sarcoma tumors

  Dataset EGAD00001009385

• 9 samples variant calling data

  This dataset comprise results of mutect2 variant calling in vcf format on 9 samples of rosette forming brain tumors (5 with paired normal tissue and 4 without). Only variants specific to the tumor where kept to comply with patients consent.

  Dataset EGAD00001009266

• Targeted sequencing of candidate regions on chromosome 22q predisposing to multiple schwannomas

  Targeted sequencing of candidate regions on chromosome 22q predisposing to multiple schwannomas

  Dataset EGAD00001008271

• Matched WXS of 147 lung cancer patients treated with immunotherapy

  This data includes whole exome sequencing of matched normal-tumor samples of patients who have received immunotherapy. '-1' refers to matched normal sample and '-2' refers to matched tumor sample.

  Dataset EGAD00001005211

• HDAC and PI3K Antagonists Cooperate to Inhibit Growth of MYC-driven Medulloblastoma

  HDAC and PI3K Antagonists Cooperate to Inhibit Growth of MYC-driven Medulloblastoma

  Dataset EGAD00001001899

• In vitro mutational load

  Clonally expanded human pluripotent and adult (liver + intestine) stem cell clones were subjected to whole genome sequencing to determine the mutational impact of in vitro culture

  Dataset EGAD00001004104

• macIDR validation data

  RNA-seq of 24 M-CSF differentiated human peripheral monocyte-derived macrophages (MDMs) activated with short exposure (3hours) to LPS, or long exposure (24 hours) to LPS, LPS with IFNγ, IFNγ, IL-4, IL-10, and dexamethasone.

  Dataset EGAD00001004584

• WES of Adenoid Cystic Carcinoma Treated with Axitinib and Avelumab

  To determine potential mutational biomarkers of response to combination axitinib and avelumab, whole exome sequencing was performed on 24 adenoid cystic carcinomas treated with combination axitinib and avelumab with paired normal samples.

  Dataset EGAD50000002467