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• Targeted sequencing data on sequential liquid biopsy samples from mCRPC patients receiving cabazitaxel

  Sequencing data from mCRPC patients receiving cabazitaxel. Targeted sequencing data of prostate cancer relevant genes using the PCF-SELECT capture panel. cfDNA from baseline, on-treatment and progression samples taken on cabazitaxel were sequenced as well as patient match WBC DNA

  Dataset EGAD50000001840

• Triple-negative breast cancer sequencing data

  Single-cell RNA sequencing and spatial transcriptomic sequencing data associated with manuscript 'Ectopic NMDAR expression in cancer unmasks germline-encoded autoimmunity'

  Dataset EGAD50000002266

• Human embryonic stem cells dopaminergic neurons scRNA-seq

  The dataset includes 2 samples of Single cell RNA-seq (10X Genomics) from Human Embryonic stem cells. 2 samples with 2 replicates of timepoints 17 and 28 of dopaminergic neuron differentiation.

  Dataset EGAD50000001592

• Melanoma transcriptomic data from patients undergoing immunotherapy

  This dataset contains raw RNA sequencing data from melanoma patient tumor samples collected before and during immunotherapy. The data support investigation of treatment-related changes in tumor cell populations. Samples were analyzed as part of a study exploring cellular responses to immune-based therapies.

  Dataset EGAD50000001569

• eSENSES control samples

  This dataset comprises BAM files from 18 control samples analyzed with the eSENSES targeted NGS panel. Spanning approximately 2 Mb, the panel features around 15,000 evenly distributed genome-wide SNPs, over 500 focal SNPs targeting key breast cancer driver regions, and more than 2,000 exons from 81 commonly altered genes.

  Dataset EGAD50000001167

• RNAseq of samples from CLL patients treated with ibrutinib in vivo

  The dataset contains RNA sequencing data from 22 paired samples of 11 patients before and during ibrutinib therapy (median time on therapy 2 weeks; range 1-12 weeks). The sequencing was performed in two batches.

  Dataset EGAD50000000879

• Exome sequencing analysis of BCP-LBL patients samples

  In order to perform comprehensive SNV and CNA analyses of a cohort of BCP-LBL patients, we performed whole exome sequencing of 41 tissue samples from BCP-LBL patients. Because the material was available as FFPE, the target coverage of the samples was >200x.

  Dataset EGAD50000000418

• Single-cell TCR sequencing data of patients with T follicular helper cell lymphomas

  This dataset contains single-cell TCR sequencing data generated by the Cellranger pipeline (v3.1.0, 10X Genomics) from 9 LN and 16 PB samples of 14 patients with T follicular helper cell lymphomas (TFHLs) as well as 7 homeostatic LN (HLN) samples.

  Dataset EGAD50000000403

• Single-cell RNA sequencing data of patients with T follicular helper cell lymphomas

  This dataset contains single-cell count data generated by the Cellranger pipeline (v3.1.0, 10X Genomics) from 9 LN and 16 PB samples of 14 patients with T follicular helper cell lymphomas (TFHLs) as well as 7 homeostatic LN (HLN) samples.

  Dataset EGAD50000000402

• Single-cell BCR sequencing data of patients with T follicular helper cell lymphomas

  This dataset contains single-cell BCR sequencing data generated by the Cellranger pipeline (v3.1.0, 10X Genomics) from 5 LN and 1 PB samples of 5 patients with T follicular helper cell lymphomas (TFHLs) as well as 7 homeostatic LN (HLN) samples.

  Dataset EGAD50000000400

• Illumina Infinium MethylationEPIC Array IDAT files generated from 11 glioma patient samples

  This dataset includes IDAT files from 6 IDH-mutant, 5 IDH-wild-type glioma patient samples of unmatched initial and recurrent timepoints profiled using the Illumina Infinium MethylationEPIC Array.

  Dataset EGAD00010002157

• Whole-genome sequencing and H3K4me3 profiling of plasma cell-free DNA

  Epigenomic characterization of breast cancers by profiling circulating nucleosomes isolated from patient plasma using cell-free chromatin immunoprecipitation followed by sequencing (cfChIP-seq).

  Study EGAS50000001759

• ChIPseq of neuroblastoma

  This dataset contains 4 samples (2x input and 2x H3K27ac ChIPseq) in the IC-pPDXC-63 cell line.

  Dataset EGAD00001006557

• Whole exome DNA sequencing data of pretreatment tumor biopsies and matched blood samples of patients treated in the OpACIN-neo trial

  The dataset includes whole exome DNA sequencing on pre-treatment tumor biopsies of lymph node metastases (n=60) matched with blood samples (n=60)

  Dataset EGAD00001006730

• Personalised therapy with MEK inhibition leads to a sustained complete response in an adolescent patient with a recurrent malignant peripheral nerve sheath tumor

  Whole genome sequencing of tumour (90X) - normal (30X) patient pair and bulk transcriptome sequencing (80M PE reads) of tumour sample.

  Dataset EGAD00001006793

• Lifelines-DEEP plasma un-targeted metabolomics 1054 baseline and 311 4-year followup

  Lifelines-DEEP plasma un-targeted metabolomics

  Dataset EGAD00001006953

• IFNL4 Organoid Transcriptome Profiles

  RNAseq of liver organoids with a dG genotype (B20, nt115, U15) and with a TT genotype (nt5, U16, U19) was performed, which was used to study the impact of IFNλ4 on the cellular response to Sendai viral infection.

  Dataset EGAD00001007820

• SmartSeq2 index cultures

  SmartSeq2 read out of index cultured cell sorted with the classification and erythroid-myeloid panel developed in main Figure 6.

  Dataset EGAD00001008187

• RNA-seq of HCC patients undergoing sorafenib treatment.

  RNA-seq dataset (BAM files) of 28 HCCs and 19 non-tumor livers derived from 8 patients undergoing sorafenib treatment.

  Dataset EGAD00001008204

• RNAseq fastq files of MCL control, NOTCH1 & NOTCH2 samples

  Raw RNAseq paired end fastq files of MCL control samples (3 samples) and MCL samples transduced with a retrovirus expressing mutated NOTCH1 (3 samples) or NOTCH2 (3 samples). Instrument used: Illumina NovaSeq 6000

  Dataset EGAD00001008346

• Pediatric high grade glioma RNA-Seq

  We performed RNA-Seq in DIPG and hemispheric HGG.

  Dataset EGAD00001008278

• Whole-exome sequencing of HCCs undergoing sorafenib treatment

  Dataset consists of 25 HCCs and 9 non-tumor livers from 8 patients.

  Dataset EGAD00001008216

• The integrated genomic and immune landscapes of lethal metastatic breast cancer.

  We report on the extensive molecular profiling of multiple individual metastases from 10 warm autopsies of patients with lethal multi-therapy resistant breast cancers.

  Study EGAS00001002703

• RNA-Seq of chronic lymphocytic leukemia

  398 runs and 184 samples of CLL paired RNA-Seq. Sequences were prepared with the Illumina TruSeq RNA Kit. Paired sequencing was done on Hiseq2000 or Hiseq2500.

  Dataset EGAD00001009637

• WES CRAM files of HUG-CEL Covid-19 Genomics Study

  Whole Exome Sequencing Dataset (CRAM files) of 415 admixed Brazilians with Covid-19 extreme phenotypes from recovered nonagenarians and centenarians to deceased adults.

  Dataset EGAD00001009652