22937 results for "ega"

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• Dundee Metformin response GWAS Phenotype 2016

  Variation in the Glucose Transporter gene SLC2A2 is associated with glycaemic response to metformin

  Dataset EGAD00001002277

• 20200417_PNET_methylation_paper

  Illumina platform RNA-seq data from 47 Pancreatic neuroendocrine tumour samples

  Dataset EGAD00001006063

• Accelerated single cell seeding in relapsed multiple myeloma

  25 Whole genome sequencing data cases

  Dataset EGAD00001006119

• Phylogenetic reconstruction of breast cancer

  This dataset contains the fastq files used for this study

  Dataset EGAD00001006121

• T200 sequencing Phase Ib of olaparib and capivasertib

  T200 sequencing (Phase Ib of olaparib and capivasertib)

  Dataset EGAD00001006841

• Data upcycling, powered by EGA

  In 2012 a collaborative effort headed by the teams of Carlos Caldas in Cambridge, UK and Samuel Aparicio, Canada, produced a pivotal study aimed at defining the mutational landscape of breast cancer. They gathered a collection of over 2000 breast cancer samples (METABRIC) associated with long-term clinical follow-up. They delineated an array of inherited and somatically acquired genetic variants and associated them to gene expression. This led to the identification of putative cancer-driving events and improved stratification of breast cancer patients. The study elicited huge attention and was tackled as herculean effort by fellow researchers. Cristina Curtis and her colleagues deposited the data in the EGA archive (EGAS00000000083). What they probably could not foresee is that their data would be reused more than 100 times, becoming one of the most downloaded datasets at EGA. In 2015, Frederik S. Varn and colleagues accessed the above-mentioned data from the New Hampshire, USA, to correlate it to transcriptional programs of hematopoietic cells infiltrated in breast tumours and found that those can influence patients' prognosis. Their findings, published in Nature Communications, improved the understanding of the interplay between immune system and cancer. Again, in 2017 the dataset was downloaded by an Italian/Polish collaboration and used to corroborate their mechanistic study that demonstrate how a long non-coding RNA (lncRNA) is aberrantly localized into the chromatin, where it modulates oncogenic isoforms expression, thus contributing to breast cancer. To date, the METABRIC dataset has been reused to contribute to 147 publications. Its impact on breast cancer research is incalculable, and it even spread beyond that, with recent contributions to the understanding of pan-cancer mechanisms and features. Some of the publications are translating into improvements in diagnosis and treatment of different types of breast cancer. This is just an example of how data upcycling can amplify the potential of any dataset, well past the scope of its creation, the imagination of its owners and any geographical border. At EGA, we are proud to empower such fruitful worldwide cycles of knowledge, providing a platform that enables safe sharing of sensitive genetic data.

  Blog data-upcycling-powered-by-ega

• Glioma Genomics Committee

  Dac EGAC00001000153

• MSI-Exome-DAC Team Microsatellites Instability and Cancer, INSERM Hospital Saint-Antoine, Paris 12, France Carte d'identité des tumeurs, French league against cancer, Paris France

  Dac EGAC00001000665

• UCSF Sebaceous Carcinoma DAC for review of sequence data release from manuscript in Nature Communications, based in the UCSF Departments of Dermatology and Pathology

  Dac EGAC00001000850

• Data access committee (DAC) in the Graduate School of Medical Science and Engineering (GSMSE) at Korea Advanced Institute of Science and Technology (KAIST)

  Dac EGAC00001001643

• Brain Tumor UCSF DAC

  Dac EGAC00001001682

• DAC of The polarity and specificity of antiviral T lymphocyte responses determine susceptibility to SARS-CoV-2 infection in cancer patients and healthy individuals

  Dac EGAC00001002517

• Early on-treatment changes in circulating tumor DNA fraction and response to enzalutamide or abiraterone in metastatic castration-resistant prostate cancer - Data Access Committee

  Dac EGAC00001003128

• EGAD00000000012

  WTCCC1 project Multiple Sclerosis (MS) samples

  Dataset EGAD00000000012

• EGAD00000000048

  Sequencing data from oestrogen-receptor-alpha-positive metastatic lobular breast cancer sample

  Dataset EGAD00000000048

• EGAD00010000722

  Pilot experiment on functional genomics in osteoarthritis (coreex)

  Dataset EGAD00010000722

• EGAD00010000232

  WTCCC2 samples from Type 2 Diabetes Cohort

  Dataset EGAD00010000232

• EGAD00010000296

  1958BC control samples only (Hap550)

  Dataset EGAD00010000296

• EGAD00010000387

  Cambridge control samples using a 1.2M genotyping chip from Illumina

  Dataset EGAD00010000387

• CLL cancer Sample Sequencing

  CLL cancer Sample Sequencing

  Dataset EGAD00001000004

• Various Cancer Fusion Gene Sequencing

  Various Cancer Fusion Gene Sequencing

  Dataset EGAD00001000005

• ADCC Rearrangement Screen

  ADCC Rearrangement Screen

  Dataset EGAD00001000062

• Multifocal Breast Project

  Multifocal Breast Project

  Dataset EGAD00001000068

• Gastric and Esophageal tumour rearrangement screen

  Gastric and Esophageal tumour rearrangement screen

  Dataset EGAD00001000075

• Acute Myeloid Leukemia Sequencing

  Acute Myeloid Leukemia Sequencing

  Dataset EGAD00001000095

• Myelodysplastic Syndrome Exome Sequencing

  Myelodysplastic Syndrome Exome Sequencing

  Dataset EGAD00001000117

• DATA_SET_Comparing_sequencing_four_proto-typical_Burkitt_lymphomas_BL_IG-MYC_translocation

  DATA_SET_Comparing_sequencing_four_proto-typical_Burkitt_lymphomas_BL_IG-MYC_translocation

  Dataset EGAD00001000176

• Whole genome sequencing of colon samples

  Whole genome sequencing of colon samples

  Dataset EGAD00001000214

• UK10K_NEURO_ABERDEEN REL-2012-07-05

  EGAD00001000227_UK10K_NEURO_ABERDEEN_REL_2012_07_05

  Dataset EGAD00001000227

• UK10K_NEURO_EDINBURGH REL-2012-07-05

  EGAD00001000233_UK10K_NEURO_EDINBURGH_REL_2012_07_05

  Dataset EGAD00001000233

• UK10K_NEURO_GURLING REL-2012-07-05

  EGAD00001000237_UK10K_NEURO_GURLING_REL_2012_07_05

  Dataset EGAD00001000237

• De novo mutations in schizophrenia

  De novo mutations in schizophrenia

  Dataset EGAD00001000251

• DATA FILES FOR SJHYPO

  Hypodiploid acute lymphoblastic leukemia whole genome sequencing

  Dataset EGAD00001000260

• RNA Editing Transcriptome

  Transcriptome sequencing data of tumor and 10 matched normal samples of the EGAS00001000495 project

  Dataset EGAD00001000627

• WTCCC3_Pre-Eclampsia

  WTCCC3 UK maternal cases of pre-eclampsia

  Dataset EGAD00010000854

• Sequencing data for ICGC Oesophageal Adenocarcinoma tissue samples - side_cases_barretts

  Dataset EGAD00001001379

• REL-2016-09_EGAS00001000867

  HipSci - Healthy Normals - Expression Array - September 2016

  Dataset EGAD00010001143

• REL-2016-10_EGAS00001001274

  HipSci - Bardet-Biedl Syndrome - Methylation Array - October 2016

  Dataset EGAD00010001145

• RNA-seq data from diagnosis and relapse samples of Down Syndrome acute lymphoblastic leukemia.

  Dataset EGAD00001003280

• Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma

  Dataset EGAD00001003324

• Transcriptome profiling by array after Kit FFPEsensation WT Affymetrix

  Affymetrix GeneChip® Human Transcriptome Array 2.0

  Dataset EGAD00010001275

• REL-2017-07_866

  HipSci - Healthy Normals - Genotyping Array - July 2017

  Dataset EGAD00010001328

• ega_SJLIFE_BMD_ALL

  A discovery cohort of 856 adult survivors of pediatric ALL

  Dataset EGAD00010001396

• miRNA profiling of human plucked hair follicle

  miRNA profiling of human plucked hair follicle from frontal and occipital scalp

  Dataset EGAD00010001500

• UKHLS_DNAmethylation

  Bisulfite Converted DNA obtained from Whole Blood analysed on IlluminaHumanMethylationEPIC BeadChip microarrays processed with bigmelon R package

  Dataset EGAD00010001521

• EGAS00001001728_REL-2016-04

  HipSci - Embryonic Stem Cells - Methylation Array - April 2016

  Dataset EGAD00010000909

• EGAS00001001730_REL-2016-04

  HipSci - Embryonic Stem Cells - Expression Array - April 2016

  Dataset EGAD00010000910

• chr6_allsamples_imputated

  Chromosome 6 imputed genotypes of samples genotyped on the Axiom Human Genotyping SARS-CoV-2 array (GRCh38)

  Dataset EGAD00010002539

• REL-2014-11_3

  HipSci - Healthy Normals - Expression Array - November 2014

  Dataset EGAD00010000775

• TwinsUK_EpiTwin_DNA_Methylome

  MeDIP-seq RPM chromsome BED files for Peripheral Blood from EPITWIN Project (Columns 4-4353 represent samples)

  Dataset EGAD00010000983