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• scRNAseq + TCRseq of n-irAE patients

  Here we performed multimodal analysis (5'scRNAseq and TCR-seq) on PBMCs from cancer patients developing or not neurological adverse events (n-irAEs) following immune checkpoint inhibition (ICI) treatment.

  Study EGAS50000000603

• Genomic Structural Variants in Japanese Malignant mesothelioma patients

  We extracted genomic DNAs from established mesothelioma cell lines from Japanese malignant mesothelioma patients. We sequenced those genomic DNAs using 10X Genomics sequencing technologies, and analyzed genomic structural variations.

  Study JGAS000176

• Cohort B RNA sequencing

  Cohort B includes IDH-wild type, EGFR amplified, surgically derived glioblastoma tissue samples from male and female individuals. RNA was isolated from FFPE glioma tissue of each sample from Cohort B.

  Study EGAS50000000953

• WGS of all Patients Listed within this Study

  This dataset contains WGS from whole blood of patients II.2, II.3, III.1-4 and WGS from fibroblasts of patients III.2 and III.3. All WGS was performed on an Illumina NextSeq2000 to a minimum depth of 250 million read pairs (2x150nts).

  Dataset EGAD50000002362

• Whole exome sequencing of ETV::RUNX1 positive acute lymphoblastic leukemia

  This dataset contains whole exome sequencing of ETV::RUNX1 positive acute lymphoblastic leukemia. Germline and leukemia samples were sequenced in pairs. A total of 94 samples were sequenced and reads were aligned to hg19 genome reference. Aligned bam files are provided in this data set.

  Dataset EGAD50000001184

• INCLIVA-CC-WES

  This dataset consists of WES NGS paired-end raw data (FASTQ R1, R2 and UMI sequence) obtained from 25 localised colon cancer patients. Specifically, we have 25 primary tumor tissue samples, 17 metastatic tissues, 25 white blood cell samples, 25 plasma samples collected at relapse, 12 baseline plasma samples and 15 plasma samples post-surgery.

  Dataset EGAD50000000293

• Cord blood progenitor CITE-seq dataset

  Sequencing results of single-cell transcriptome and antibody libraries from two biological experiments of cord blood progenitor cells. Four samples from different time points were processed using 10X Genomics Chromium Next GEM Single Cell 3’ Reagent Kits v3.1. Gene expression and antibody-derived libraries were sequenced separately.

  Dataset EGAD50000000405

• Whole genome sequencing of preneoplasia lung adenocarcinoma

  Whole genome sequencing of 42 pulmonary samples including lung preneoplasia atypical adenomatous hyperplasia (AAH, N=5), adenocarcinoma in situ (AIS, N=7), minimally invasive adenocarcinoma (MIA, N=6) and invasive lung adenocarcinoma (ADC, N=8) and adjacent lung tissues (Normal, N=16).

  Dataset EGAD50000000396

• RNAseq of preneoplasia lung adenocarcinoma

  RNA sequencing of 168 pulmonary samples including lung preneoplasia atypical adenomatous hyperplasia (AAH, N=38), adenocarcinoma in situ (AIS, N=22), minimally invasive adenocarcinoma (MIA, N=19) and invasive lung adenocarcinoma (ADC, N=38) and adjacent lung tissues (Normal, N=62).

  Dataset EGAD50000000395

• COLONOMICS small RNA sequencing

  This dataset consists of SOLiD small RNA-seq of 250 colorectal samples: 100 tumor tissue samples, 100 normal tissue samples (adjacent to tumor sites) and 50 matched control samples of healthy individuals. CSfasta and qual files converted to single fastq files prior to uploading.

  Dataset EGAD00001004827

• Whole genome sequencing identified biomarker of response to PD1 blockade in Natural-killer/T-cell lymphoma

  WGS data of 13 and TCS data of 8 NKTCL patients. Significant association of PD-L1 rearrangements with objective response to anti-PD1 (pembrolizumab).

  Study EGAS00001002420

• Whole-genome, whole-exome and transcriptome sequencing of pancreatic ductal adenocarcinomas from young adults (NCT MASTER)

  Whole-genome, whole-exome and transcriptome sequencing of pancreatic ductal adenocarcinomas from young adults reveals recurrent NRG1-fusions in KRAS wild-type tumors.

  Dataset EGAD00001004068

• Whole genome shotgun sequencing and somatic mutations data in Hepatocellular carcinoma

  There are 88 paired samples from HCC patients including tumors and matched adjacent normal tissues which were sequencing by Illumina HiSeq 2000 platform.

  Dataset EGAD00001003760

• Sequencing data of primary uveal melanomas and their matched metastases

  We performed targeted DNA sequencing of primary uveal melanomas and their matched metastases from 35 patients, analyzing a total of 124 tissues. Sequencing was performed on an Illumina HiSeq 2500 instrument using a panel of 538 genes commonly involved in cancer. 124 BAM files were generated.

  Dataset EGAD00001004453

• Total RNA-seq of intestinal gluten tetramer+ and tetramer- CD4+ T-cells from celiac disease patients

  Total RNA-seq of intestinal gluten tetramer+ and tetramer- CD4+ T-cells from celiac disease patients, as well as intestinal CD4+ T-cells from healthy control individuals (paired-end fastq files).

  Dataset EGAD00001004146

• VCF files of Roma and non-Roma Romanians

  VCF files with whole genome sequencing data of 49 individuals of European/Romanian descent, and 50 individuals of Roma (Romani/Rroma) ethnic background from Romania.

  Dataset EGAD00001004982

• Organoid Derivation Project TGS: Release 2

  Sequencing of tissue samples and their derived organoids from oesophageal, pancreatic and colorectal cancer patients.

  Dataset EGAD00001004999

• Organoid Derivation Project WGS: Release 1

  Sequencing of tissue samples and their derived organoids from oesophageal, pancreatic and colorectal cancer patients.

  Dataset EGAD00001005000

• Organoid Derivation Pilot: RNAseq

  Sequencing of tissue samples and their derived organoids from oesophageal, pancreatic and colorectal cancer patients.

  Dataset EGAD00001005001

• WGS paired B-Cell lymphoma cells sorted according to CD48

  paired WGS data of one tumor of one patient with nodal B-cell lymphoma. Tumor cells were sorted according to CD48 expression in a high and low fraction. Library preparation with TruSeq Nano and sequencing on Hiseq XTen.

  Dataset EGAD00001006058

• Gluten reactive and non-reactive T-cells from treated celiac disease patients on a gluten challenge sampled at day 6

  Gluten reactive T-cells from blood samples from patients undergoing a 3 day gluten challenge. Samples were collected on day 6. Both gluten reactive and non-gluten reactive T-cells were sequenced.

  Dataset EGAD00001006899

• Single cell TCR Analysis of regulatory Tcells from blood, fat and skin

  Regulatory Tcells were FACS sorted and processed with 10x Genomics Chromium Next GEM SingleCell V(D)J Reagents Kits v1.1 sequencing. In total 17 samples were processed. Fastq files are supplied.

  Dataset EGAD00001007661

• small RNA next generation sequencing in head and neck cancer

  small RNA next generation sequencing in head and neck cancer

  Dataset EGAD00001008402

• RNA-seq data from a variety of pediatric brain tumors

  RNA-seq (n=52) data from a variety of pediatric brain tumors including ependymoma (PFA, PFB, Ste, spinal), medulloblastoma (G3, G4, SHH), high grade glioma (H3K27 and H3-WT), pilocytic astrocytoma, and more. Raw data provided as FASTQ. Data generated on Illumina HiSeq2500.

  Dataset EGAD00001007915

• Hi-C sequencing from a variety of pediatric brain tumors

  Hi-C (n=72) data from a variety of pediatric brain tumors including ependymoma (PFA, PFB, Ste, spinal), medulloblastoma (G3, G4, SHH), high grade glioma (H3K27 and H3-WT), pilocytic astrocytoma, and more. Raw data provided as FASTQ. Data generated on Illumina HiSeq2500.

  Dataset EGAD00001007914