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• The evolution of hematopoietic cells under cancer therapy

  WGS TAML samples with their remission controls obtained from bone marrow.

  Dataset EGAD00001007706

• RNA-seq of T-ALL patient-derived xenograft (PDX) samples

  This dataset includes 4 samples profiled by high-throughput Illumina sequencing, in bam format, aligned to GRCh37. Human patient T-ALL samples were serially propagated as xenografts in immunodeficient mice. The samples were collected after development of frank leukemia in recipient mice.

  Dataset EGAD00001009749

• Ancient Yakuts genomes and metagenomes

  Read data and bam alignments for 124 ancient yakuts

  Dataset EGAD50000001903

• Detection of causative structural variants using long read whole genome sequencing in patients with non-syndromic autism spectrum disorder

  This study involved performing long read whole genome sequencing using Oxford Nanopore Technology platform on to detect causative structural variants in patients with non-syndromic autism spectrum disorder. This study was performed on 23 such children in whom prior karyotyping, Fragile-X analysis (in males), chromosomal microarray and whole exome sequencing did not identify a causative variant.

  Study EGAS50000000842

• Leukemia stem cell containing fractions

  ATAC-seq performed on leukemic stem cell fractions with different engraftment potential. Leukemic cells were sorted out of Acute Myeloid Leukemia patient samples based on CD34/CD38 status. Samples were annotated based on an independent engraftment assay in mice as LSC+ (engrafting) and LSC- (not engrafting). Omni-ATAC-seq was carried out to compute differential enrichment of transposable elements in chromatin accessible regions.

  Study EGAS00001004893

• Application of Hi-C sequencing to detect structural variants in B-cell acute lymphoblastic leukemia

  Large structural variants are easily detected by Hi-C sequencing as strong, distant signals on a Hi-C contact map. Translocations are frequently evident in B-ALL and accurate identification of these translocations can guide clinical treatment options. Here were apply shallow Hi-C sequencing as an unbiased, cost-effective approach to identify translocations among B-ALL patients.

  Study EGAS00001005605

• FWO-project G.0687.12_X10-WGS

  Profiling subclonal architecture and phylogeny in tumors by whole-genome sequence data mining and single-cell genome sequencing

  Dataset EGAD00001001429

• Colorectal organoids and tumour tissue

  Whole genome sequencing of single cell derived organoids from normal colon tissue and colorectal cancer.

  Dataset EGAD00001001447

• UCSF WCDT WGS/WGBS mCRPC

  This dataset contains 29 paired FASTQ files from whole-genome bisulfite sequencing (WGBS) assay performed on mCRPC tumors. Sequencing was performed using 150nt paired reads generated by a Novaseq 6000 instrument. It also contains whole-genome sequencing bam files aligned to hg38 using BWA from 36 patients, with tumor and matched tumor-adjacent normal samples. Sequencing was generated using HiSeq X Ten.

  Study EGAS00001006649

• Comprehansive analysis of somatic mutations and genetic variations with whole genome sequencing

  Indetification of stractural variations by using of long read whole genome sequencing data

  Study JGAS000516