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• Evaluating CRISPR-based Prime Editing for cancer modeling and CFTR repair in organoids

  Study EGAS00001005358

• Orthotopic murine Group 3 medulloblastoma in C57Bl/6 mice treated with saline, cyclophosphamide or gemcitabine

  Study EGAS00001005846

• Orthotopic murine Group 3 medulloblastoma in C57Bl/6 mice treated with sham or craniospinal irradiation

  Study EGAS00001005847

• NPY methylated ctDNA is a promising biomarker for treatment response monitoring in metastatic colorectal cancer

  Study EGAS00001006820

• RHD_FJ_HC24_Cases

  Rheumatic heart disease cases recruited in Fiji

  Dataset EGAD00010000961

• Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells

  Study EGAS00001007026

• Accessibility Over Transposable Elements Reveals Genetic Determinants of Stemness Properties in Normal and Leukemic Hematopoiesis

  Study EGAS00001007191

• DNA methylation using EPIC array in UK population study

  See www.understandingsociety.ac.uk

  Study EGAS00001002836

• RFX6-mediated dysregulation defines human β cell dysfunction in early type 2 diabetes

  Study EGAS00001006273

• Dataset of Recurrent resistance mutations to lirafugratinib delineate treatment sequences for FGFR2-driven tumors

  This dataset is made of 23 pairs of RNAseq and 36 pairs of Exome-seq, both sequenced from Illumina Novaseq. This includes 47 samples, composed of 25 tumors, 13 healthy and 9 xenograft

  Dataset EGAD50000001981

• Exome Sequencing data from infertility cases.

  This dataset includes exome sequencing (ES) from a cohort of patients with infertility. Sequencing was performed on genomic DNA extracted from blood, using Agilent SureSelect XT Low Input exome capture and Illumina NovaSeq 6000 paired-end sequencing and is intended to facilitate research into novel genetic causes of infertility.

  Dataset EGAD50000001881

• cfDNA sWGS BAM — NSCLC stage I–III

  Plasma cfDNA sWGS for NSCLC patients (stage I–III), blood drawn pre-operatively, CHU Montpellier/LUNGDOC study. Libraries: DSP as recorded. Sequencing provider IntegraGen (2022–2024). Alignment to GRCh38 (hg38 canonical), BWA-MEM; BAMs sorted/indexed; only primary mapped reads retained (analysis pages list -F/MAPQ). Controlled access.

  Dataset EGAD50000001878

• WGS from 9 MPNSTs from 2 individuals, including relapses and metastasis. Data from Ortega-Bertran et. al.

  WGS from 2 individuals with MPNSTs. Multiple MPNSTs (independent tumor, relapses and metastasis) from each individual. Data from "Personalized Medicine Strategy for MPNSTs: Using Precision Oncology on PDOX Models to Inform Tumor Boards" by Ortega-Bertran et.al.

  Dataset EGAD50000002171

• H3K27ac HiChIP Dataset for 19 T-ALL patients and one normal control sample

  19 H3K27ac HICHIP from T-ALL patient samples and one healthy normal control sample. Reads were aligned to HG38 reference.

  Dataset EGAD50000000023

• A novel orthotopic patient-derived xenograft model of radiation-induced glioma following medulloblastoma

  DNA methylation arrays were performed to molecularly subtype these samples based on Capper D, Jones DTW, Sill M, et al. DNA methylation-based classification of central nervous system tumours. Nature. 2018;555(7697):469-474. doi:10.1038/nature26000

  Dataset EGAD00010002017

• Lifelines NEXT phenotypes

  This dataset contains list of basic phenotypes for Lifelines NEXT participants including: - linkage to metagenomics sequencing - Infant ID - family ID - gestational age - parity - maternal age at delivery - maternal smoking history - maternal hypertension at pregnancy - infant sex - place of delivery - delivery mode - infant weight at birth - infant weight growth slope - infant breastfeeding (never/ever) - infant eczema

  Dataset EGAD50000002677

• ICR_RNASeq_pHGG

  RNA sequencing of paediatric high grade gliomas and diffuse intrinsic pontine gliomas. RNA was sequenced from fresh frozen surgical material or from primary cells cultured under stem cell conditions. RNA was subjected to Illumina whole transcriptome paired end sequencing. Data is provided as paired-end FASTQ files

  Dataset EGAD00001004116

• Single-cell Transcriptome for glioblastoma intra-tumoral heterogeneity

  Single-Cell RNA Sequencing of 355 cells isolated from 7 tissue fragments of 3 patients corresponding to locally adjacent tumor, multifocal with recurrence and sections segregated by a marker of tumor cellularity (5-ALA).

  Dataset EGAD00001002249

• Clinical exome profiling of 7 members of a family with cases of familial Alzheimer's disease

  This dataset includes "clinical exome" profiling (approximately 4000 genes related to diseases) on individuals (n=7) from a family with a familial history of Alzheimer's disease. Two affected cases ad five cases without dementia are included.

  Dataset EGAD00001005320

• Untargeted serum metabolomics profiled by Metabolon Inc.

  Raw untargeted metabolomics profiled by Metabolon Inc. for 540 samples from healthy individuals. Files include sample names and run details which can be matched to their metagenomic sequencing samples from PRJEB11532 and PRJEB17643. Information regarding metabolite metadata is also available, including

  Dataset EGAD00001006247

• paired-EXOME (WES) sequencing with SureSelect-V5+UTRs of B-cell lymphoma

  Tumors and control of nodal B-cell lymphoma of one patient. WES sequencing on Illumina HiSeq 4000 with Agilent SureSelect V5+UTRs. Bam files were aligned with bwa mem to hg19.

  Dataset EGAD00001006059

• HV31 - MGI single-tube long fragment read (stLFR) linked-read sequencing

  MGI single-tube long fragment read (stLFR) linked-read sequencing data for individual HV31 generated using DNA from CD14+ monocytes, to a sequencing depth of ~51×.

  Dataset EGAD00001007045

• WES CRAM files of HUG-CEL Covid-19 Genomics Study

  Whole Exome Sequencing Dataset (CRAM files) of 415 admixed Brazilians with Covid-19 extreme phenotypes from recovered nonagenarians and centenarians to deceased adults.

  Dataset EGAD00001009652

• Colonbiome shot-gun metagenomics

  156 samples of shot-gun gut metagenomics, corresponding to 51 patients with CRCm 54 patients with adenoma, and 51 healthy controls

  Dataset EGAD00001010068

• Single-cell RNA-sequencing of nivolumab-treated glioblastoma

  Single-cell RNA-sequencing of 8 patients, from primary and relapse tumour (total of 16 samples). Patients were treated with nivolumab prior to relapse surgery.

  Dataset EGAD00001010843