This dataset contains the CRAM files of the samples used for the article "Neutrophil extracellular traps have auto-catabolic activity and produce mononucleosome-associated circulating DNA" published in Genome Medicine.
Targeted sequencing data to look for the involvement of genes in the RAS-MAPK pathway, angiogenesis and brain vascular disorders among others, in brain AVMs
Data includes whole exome sequenced bam files for matched tumor-normal pairs from the study.
Clinical data for IMpower150 (one patient per line): anonymized_patient_id, train_test_split, ctDNA_status, ARM1, OS_months, OS_event, PFS_months, PFS_event, TTEOS_rebaseline_BL, TTEPFS_rebaseline_BL, TTEOS_rebaseline_C2D1, TTEPFS_rebaseline_C2D1, TTEOS_rebaseline_C3D1, TTEPFS_rebaseline_C3D1, TTEOS_rebaseline_C4D1, TTEPFS_rebaseline_C4D1, TTEOS_rebaseline_C8D1, TTEPFS_rebaseline_C8D1, pdl1_high, number_metastatic_sites, baseline_ECOG, age, sex_female, history_of_tobacco_use, sld_baseline, sld_wk6, sld_percent_change_bl_to_wk6, sld_difference_bl_to_wk6, AGEGRP, tumor_assessment_week_6, tumor_assessment_week_12, tumor_assessment_week_18, tumor_assessment_week_24, PFS_days, days_between_randomization_c3
reference whole exome sequence serving as a reference of individuals. Includes the fastq files of each individual (labelled S1-S5) and the called variants in vcf format merge for all individuals.
This dataset includes fastq files for total RNAseq of 104 patient biopsies with metastatic castration resistant prostate cancer. The RNAseq libraries were rRNA depleted and sequenced at 150bp paired-end on Illumina Novaseq.
RNAseq data generated from paired tumor frozen tissues in which the tumor organoids were established for cell-cell or cell-matrix adhesion dependency assay.
Consists of 88 cases
ZPM WES Pilot consisting of 30 samples paired tumor/normal analyzed with WES at four different laboratories in Germany.
The dataset includes RNA sequencing data on PRE- treatment biopsies of lymph node metastasis (n=80) The technology used for sequencing is llumina HiSeq 2500