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Average_5mC_Roadmap_histoneMarks
Dataset
EGAD00010002422
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Average_5hmC_Roadmap_histoneMarks
Dataset
EGAD00010002417
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Average_5hmC_Roadmap_chromatinStates
Dataset
EGAD00010002414
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Average_5mC_Roadmap_chromatinStates
Dataset
EGAD00010002413
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Lindsey E. Jones et al. Patient-derived cells from recurrent tumors that model the evolution of IDH-mutant glioma. Neuro-Oncology Advances, 2020. We established robust, versatile, and well-characterized Patient Derived Cells (PDC) of an IDH1-mutant astrocytoma and an IDH1-mutant oligodendroglioma that represents defined evolutionary stages of chemotherapy-induced hypermutation. The PDCs retain tumor subtype defining features over time as well as classic hallmarks of cancer, including anchorage independent growth and cell immortality. The integrated phylogenies composed of PDCs,single-cell-derived PDCs, patient-derived xenografts, and corresponding spatiotemporal tumor tissue samples also provide new insight into the clonality, evolutionary pattern, and immense mutational load of hypermutated IDH mutant gliomas.
Study
EGAS00001003992
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NHLBI TOPMed: Pulmonary Hypertension and the Hypoxic Response in SCD (PUSH)
Study
phs001682
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Average_5hmC_TF_sites
Dataset
EGAD00010002421
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Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS)
Study
phs001119
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NHLBI TOPMed: SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS)
Study
phs001927
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Genetic_vulnerability_of_knockout_cancer_lines
Study
EGAS00001002253
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Longitudinal Single-cell Genomic Analysis of Initial and Recurrent Meningioma
Study
EGAS50000000860
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Long-Term Oxygen Treatment Trial (LOTT-BioLINCC)
Study
phs003933
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Ribosomal Depleted Total RNA-Seq of PBMCs and Skin from Controls and Systemic Sclerosis Patients
Study
phs002902
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Average_hypermethylation_TF_sites
Dataset
EGAD00010002411
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Reference Profiles of ExRNAs in Normal Human Pregnancy
Study
phs003182
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Single Cell Analysis Reveals Immune Dysfunction from the Earliest Stages of CLL that can be Reversed by Ibrutinib
Study
phs002705
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Single-cell RNA sequencing of human IL-18R supported CAR T cells targeting oncofetal Tenascin C
Study
EGAS50000000772
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Recurrent/Metastatic Adenoid Cystic Carcinoma Treated with Axitinib and Avelumab
Study
EGAS50000001714
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Cell types of the human retina and its organoids at single-cell resolution. Cowan et al
Study
EGAS00001004561
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FFPE, buffycoat and cell free DNA from N. German esophagus cancer patients - 2021
Study
EGAS00001006813
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International Verapamil SR/Trandolapril [INVEST] Genes Study
Study
phs002319
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Discordant_Monozygotic_Twins_ALS (Epigenetics)
Dataset
EGAD00010002716
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Clinical and ctDNA data for IMpassion031
Dataset
EGAD50000001420
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Study of Osteoporotic Fractures (SOF)
Study
phs000510
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Warfarin Pharmacogenetics: Pharmacogenetic Optimization of Anticoagulant Response (POAT) and Genetic and Environmental Determinants of Warfarin Response (GEDWR)
Study
phs000708