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• GSA_2023_hg19

  Genopyting of 45 individuals using the Illumina Global Screening Array-24 v3

  Dataset EGAD00010002707

• GSA_2020_hg38

  Genopyting of 65 individuals using the Illumina Global Screening Array-24 v2

  Dataset EGAD00010002706

• GSA_2022_hg19

  Genopyting of 45 individuals using the Illumina Global Screening Array-24 v3

  Dataset EGAD00010002705

• The study of response to EGFR Blockade in Colorectal Cancer

  Dataset EGAD00001001628

• The study of response to EGFR Blockade in Colorectal Cancer

  Dataset EGAD00001001674

• AML-MRD

  AML-MRD: Aligned sequences used in the error modeling study

  Dataset EGAD00001005270

• Somatic mutations in angiosarcoma

  Here we present the genomes of three secondary angiosarcomas

  Dataset EGAD00001000735

• CITEseq data

  CITEseq data of CLL patients receiving VEN treatment for resistance study

  Dataset EGAD00001008366

• AWI-GEN 2 Microbiome Dataset

  AWI-Gen Phase 2 Microbiome Project for 1820 samples.

  Dataset EGAD00001015449

• Multiomic cell-free DNA profiling to inform molecular classification and immunotherapy outcomes in endometrial cancer

  This study involved a cell-free DNA (cfDNA) framework integrating genomic, transcriptomic and epigenomic profiling to investigate patient response to immune checkpoint inhibitors in advanced endometrial cancer (EC) with mismatch repair deficiency (dMMR).

  Study EGAS50000001582

• Large B cell lymphomas with CCND1 rearrangement have different immunoglobulin gene breakpoints and genomic profile than mantle cell lymphoma

  Next-generation sequencig data including whole-genome sequencing, whole-exome sequencing, and capture-based gene panels of large B cell lymphomas with CCND1 rearrangementas described in Özoğul,Montaner, Pol et al 2024.

  Study EGAS50000000564

• Cellular Analysis of Resistance and Evolution in IDH-mutant glioma

  We profiled a total of 75 IDH-mutant gliomas to study tumor evolution in this tumor type, among which 51 samples are presented here. These data reflect a combination of whole genome sequencing, whole exome sequencing, 10x single nucleus RNA sequencing, and 10x simultaneous single nucleus RNA and ATAC sequencing.

  Dataset EGAD50000002485

• ChIP-seq of blasts from leukemia patients and CD34+ cells from healthy donors

  CTCF ChIP-seq of 14 leukemia patients: 6 AML without 3q rearrangements, 1 AML with 3q26, 1 AML with t(3;8) and 6 T-ALL H3K27ac ChIP-seq of AML patients: 4 cases with t(3;8), another with inv(3) and another with normal karyotype. H3K27ac ChIP-seq of CD34+ cells from one healthy donor RUNX1 ChIP-seq of one t(3;8) AML patient

  Dataset EGAD00001006817

• Longitudinal ctDNA in Uveal Melanoma

  This dataset contains data from 11 uveal melanoma patients. Plasma samples were collected at baseline, 2-weeks, 3-, 6-, and 12-months post treatment (surgery/radiation). Samples underwent targeted panel, shallow whole genome, and cfMeDIP sequencing. A total of 46 plasma samples, 7 tumours, 11 buffy coats, and 10 healthy controls are included.

  Dataset EGAD00001008998

• Genetic and immune landscape evolution defines subtypes of MMR deficient colorectal cancer

  Genomic data from a cohort of 19 MMR deficient colorectal cancers and 1 MMR proficient colorectal cancer. All cases were target gene DNA sequenced using multiple primary and where available metastatic tumour regions from surgical resection samples.

  Dataset EGAD00001008334

• PanCurX Translational Research Initiative - RNA-Seq mapped and unmapped reads

  Integration of Genomic and Transcriptional Features in Pancreatic Cancer Reveals Increased Cell Cycle Progression in Metastases - RNA-Seq mapped and unmapped reads

  Dataset EGAD00001004548

• TRACERx pilot study.

  Multi-region Illumina whole-exome and/or whole-genome sequencing on tumor regions collected from early-stage NSCLC patients who underwent definitive surgical resection prior to receiving adjuvant therapy.Detected variants were validated on Ion AmpliSeq™ Custom Panel and/or Comprehensive Cancer Gene Panels.Patients covered by this dataset: L001, L002, L003, L004, L008 and L011.

  Dataset EGAD00001000900

• Dynamics of multiple resistance mechanisms in plasma DNA during EGFR‐targeted therapies in non‐small cell lung cancer - sWGS

  Shallow whole‐genome sequencing dataset on samples from three patients who underwent histological transformation to small‐cell lung cancer. Samples included in this dataset include normal buffy coat samples, plasma samples collected at diagnosis of NSCLC as well as prior to small‐cell transformation and after SCLC transformation and progression on cisplatin and irinotecan.

  Dataset EGAD00001004379

• The Nordic Centre of Excellence Programme in Molecular Medicine Data Access Committee

  Dac EGAC00000000006

• Novel de novo pathogenic variant in the GNAI1 as a cause of severe disorders of intellectual development with autistic features

  Study EGAS00001005346

• A cycling, progenitor-like cell population at the root of atypical teratoid rhabdoid tumor subtype differentiation trajectories

  Study EGAS00001008123

• Novel de novo pathogenic variant in the GNAI1 as a cause of severe disorders of intellectual development with autistic features

  Study EGAS00001005355

• 500FG DNA methylation data

  This dataset contains the DNA methylation data of 260 samples from Dutch healthy individuals.

  Dataset EGAD00010002769

• Mexican_Biobank_Genotypes

  Samples from the Mexican Biobank

  Dataset EGAD00010002361

• EGAD00010000518

  Samples from the Greek island of Crete, MANOLIS cohort

  Dataset EGAD00010000518

• The UCSF Low Grade Glioma Genome Project #1

  Dataset EGAD00001000714

• Leicester Mesothelioma Research Omics Dataset Committee

  This Data Access Committee consists of the mesothelioma research group led by Professor Dean Fennell.

  Dac EGAC50000000965

• Datasets 929/938

  Datasets Galaxy 929/938 describe the amplified single chromosome sequencing data.

  Dataset EGAD00001004457

• Cell Line Dataset

  Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

  Dataset EGAD00001001349

• Capture Hi-C

  Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci.

  Dataset EGAD00001001243

• qDNAseq CLUC dataset

  qDNAseq shallow sequencing dataset of the cell line use case.

  Dataset EGAD00001002071

• Nanopore sequencing of AML and control samples

  Three AML samples from patients with mutations in DNMT3A, IDH2, TET2, and a control sample of whole genome amplified DNA.

  Dataset EGAD50000001692

• COVID-19 progression and convalescence in common variable immunodeficiency patients

  Longitudinal analysis of single-cell RNAseq datasets of PBMCs from COVID-19 CVID patients and controls.

  Dataset EGAD50000000543

• Exome sequencing of FFPE and patient-derived cultures

  Exome sequencing of FFPE and patient-derived cultures from patients enrolled in clinical study NCT03860376

  Dataset EGAD50000000245

• Transcriptome sequencing of FFPE and patient-derived cultures

  Transcriptome sequencing of FFPE and patient-derived cultures from clinical study NCT03860376

  Dataset EGAD50000000246

• Dateset of clonal evolution in myelofibrosis

  This dataset includes bam files of tumor and paired normal samples derived from 15 patients with myelofibrosis. Tumor samples includes those before and after treatment.

  Dataset EGAD00001005282

• Sequence of breast cancer bone metastases PDX from WES

  Exome sequencing analyses obtained from 11 samples of PDX engrafted with bone metastases, match primary tumors and/or metastases and normal tissus.

  Dataset EGAD00001006071

• ALI culture bronchial cells and alveolar lung surgical resection scRNA-Seq

  ALI culture bronchial cells and alveolar lung surgical resection scRNA-Seq

  Dataset EGAD00001006185

• Gene expression from human iPSC derived cortical neurons

  Gene expression from icas9 human iPSC derived cortical neurons treated with and without doxycycline

  Study EGAS00001004782

• Expressed_fusion_transcripts_in_rare_bone_tumours

  mRNA-Seq on total RNA from primary osteoblastomas and phosphaturic mesenchymal tumours, focussing on fusion transcript expression

  Study EGAS00001000763

• Citrate synthase novel variant rewires TCA cycle to promote colorectal cancer progression

  H3K4me3, IgG, and Input ChIP-seq in overexpression of pLV Control, CS-FL and CS-ΔEx4 in SW1116 cells

  Dataset EGAD00001015543

• Comparison of HCC cell lines and primary HCCs

  Whole genome sequencing (30X) using Hiseq X TEN on 4 HCC cell lines, primary HCCs and early-passage PDCs

  Dataset EGAD00001001995

• Genomic Analysis of Mucinous Tumours (GAMuT)

  Sequencing data from primary mucinous ovarian carcinomas, benign and borderline mucinous tumours and extra-ovarian mucinous metastases.

  Dataset EGAD00001004851

• Whole genome sequencing and genotyping of samples from BFMOS (Mossi from Burkina faso)

  Whole genome sequencing and genotyping of samples from BFMOS (Mossi from Burkina faso)

  Dataset EGAD00001005011

• Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

  Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

  Dataset EGAD00001000001

• RNA-sequencing of gluten-reactive and non-reactive T-cells from blood samples of treated CeD patients during a gluten-challenge

  Gluten-specific CD4+ T cells are drivers of celiac disease (CeD). Here we aimed to characterize such cells in blood of treated CeD patients during gluten challenge with comparison to similar cells of untreated disease. Treated CeD patients underwent a 3-day gluten-challenge with blood sampling at baseline and day 6 (d6). Blood cells were stained with HLA-DQ:gluten tetramers (Tetramer). CD4+, gut-homing Tetramer+ and Tetramer- effector-memory T (TEM) cells at d6 were subjected to bulk RNA-seq (n=7).

  Study EGAS00001004988

• PEVOsq WES data

  Raw paired FASTQ data of patients at baseline from the PEVOsq cohort

  Dataset EGAD50000001013

• preQC Genotypes

  preQC genotype data from the Affymetrix AxiomTM HGCoV2 1 array in plink ped/map format

  Dataset EGAD00010002437

• GLASS-NL DNA-Methylation

  DNA-methylation data of samples included in the GLASS-NL cohort

  Dataset EGAD00010002647

• EGA_PBC_phased

  A cohort of 2886 participants of the Japan PBC-GWAS Study

  Dataset EGAD00010001533