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• McGill EMC Release 4 in tissue "venous blood" for cell type "B cell"

  McGill EMC Release 4 in tissue "venous blood" for cell type "B cell"

  Dataset EGAD00001001278

• McGill EMC Release 4 in tissue "venous blood" for cell type "T cell"

  McGill EMC Release 4 in tissue "venous blood" for cell type "T cell"

  Dataset EGAD00001001283

• Dataset for "Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability"

  Dataset for "Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability"

  Dataset EGAD00001000691

• ONT Minion reads for a patient with ataxia-pancytopenia syndrome.

  ONT Minion reads to provide 30x coverage for a patient with ataxia-pancytopenia syndrome.

  Dataset EGAD00001005022

• Exome and Transcriptome for gynecologic cancer gene-drug analysis

  Total of 180 gynecologic tumor specimens were subjected for targeted-exome and/or whole-transcriptome sequencing.

  Dataset EGAD00001005331

• ChIP-seq for AR, FOXA1 and HOXB13 on 8 prostectomy samples

  ChIP-seq for AR, FOXA1 and HOXB13 on 8 prostectomy samples, both regions with/-out tumor cells, Fastq files.

  Dataset EGAD00001005374

• Exome and Transcriptome for gastric cancer gene-drug analysis

  Newly generated 52 gastric tumor specimens were subjected for targeted-exome and/or whole-transcriptome sequencing

  Dataset EGAD00001005766

• WGS files for Roussel-ATRT-TM

  WGS files for Roussel-ATRT-TM paper titled "Atypical teratoid/ rhabdoid tumoroids reveal subgroup-specific drug vulnerabilities"

  Dataset EGAD00001009163

• RRBS for Patients of NIBIT-M4 clinical trial

  RRBS for Patients of NIBIT-M4 clinical trial

  Dataset EGAD00001009703

• RNASeq files for CIC paper data

  RNASeq files for CIC paper titled "Malignant progression of an ancestral bone marrow clone harboring a CIC-NUTM2A fusion in isolated myeloid sarcoma"

  Dataset EGAD00001009788

• Additional WGS files for Roussel-ATRT-TM

  Additional WGS files for Roussel-ATRT-TM paper titled "Atypical teratoid/ rhabdoid tumoroids reveal subgroup-specific drug vulnerabilities"

  Dataset EGAD00001010264

• Additional WXS files for Roussel-ATRT-TM

  Additional WXS files for Roussel-ATRT-TM paper titled "Atypical teratoid/ rhabdoid tumoroids reveal subgroup-specific drug vulnerabilities"

  Dataset EGAD00001010265

• single cell RNA sequencing for healthy controls and patients having NFATc1 deficiency

  single cell RNA sequencing for 4 healthy controls and 2 patients having NFATc1 deficiency

  Dataset EGAD00001011044

• DAC for Single cell RNA sequencing of peripheral blood HSPC from patients with sickle cell anemia and healthy donors.

  Data access comittee for Single cell RNA sequencing of peripheral blood HSPC from patients with sickle cell anemia and healthy donors.

  Dac EGAC50000000650

• EARLY DIAgnosis of PAncreatic Cancer (EARLY DIAPAC) study

  Whole genome sequencing of pancreatic cyst fluid for early detection and diagnosis of pancreatic cancer.

  Study EGAS50000000611

• scRNAseq dataset of vitligo dermis and epidermis

  scRNAseq dataset of vitligo dermis and epidermis for 6 patients. For each patient nonlesional and perilesional skin were sampled and processed separately.

  Dataset EGAD50000001874

• Genomic sequencing data for PNG15 and PNG16

  This data set contains genomic sequencing data and variant calls for PNG15 and PNG16.

  Dataset EGAD50000001598

• Whole exome sequencing for HNSCCs treated with immune checkpoint blockade

  Whole exome sequencing for HNSCCs treated with immune checkpoint blockade

  Dataset EGAD50000001675

• Whole exome sequencing for CIAO clinical trial

  Whole exome sequencing for CIAO clinical trial with tumor and paired normal tissue

  Dataset EGAD50000001674

• DATA FILES FOR SJOS

  DATA FILES FOR SJOS

  Dataset EGAD00001000159

• RNA-Seq files for SJOS study

  RNA-Seq files for SJOS study

  Dataset EGAD00001003154

• ChIP-Seq files for PCGP ATRX study

  ChIP-Seq files for PCGP ATRX study paper titled "MYCN Amplification and ATRX Mutations are Incompatible in Neuroblastoma"

  Dataset EGAD00001004429

• Res1_PC9_exp2_MC_01_04_22

  8 cell pellet samples for genomic DNA extraction. CRISPR PCR1 and PCR2 indexing - Please use standard Kosuke primers.

  Study EGAS00001006170

• Res1_PC9_exp1_MC_29_03_22

  8 cell pellet samples for genomic DNA extraction. CRISPR PCR1 and PCR2 indexing - Please use standard Kosuke primers.

  Study EGAS00001006169

• Res1_H23_exp2_MC_13_07_22

  8 samples are cell pellets for genomic DNA extraction. CRISPR PCR1 and PCR2 indexing - Please use standard Kosuke primers.

  Study EGAS00001006683

• DATA FILES FOR SJINF RNASeq

  DATA FILES FOR SJINF RNASeq

  Dataset EGAD00001001098

• Targeted sequencing using SPET for Mesothelioma.

  Targeted sequencing using SPET for Mesothelioma.

  Dataset EGAD00001001916

• Illumina Reads for patient with ataxia-pancytopenia syndrome.

  Illumina BAMs for a patient with ataxia-pancytopenia syndrome and both of their parents.

  Dataset EGAD00001005034

• Whole Genome Sequencing data for epigenetic subgroups of meningioma

  Bam files for 124 samples (62 tumor vs blood pairs); Whole Genome Sequencing performed on Illumina HiSeq X Ten

  Dataset EGAD00001005061

• WXS files for Mullighan Leventaki ALCL WXS

  WXS files for Mullighan Leventaki ALCL paper titled "Integrative molecular analysis of pediatric Anaplastic large cell lymphoma reveals subtypes with distinct immune suppression signatures."

  Dataset EGAD00001005936

• WGS files for Zhang GenomePaint paper

  WGS files for GenomePaint paper titled "Exploration of coding and non-coding variants in cancer using GenomePaint."

  Dataset EGAD00001006679

• RNASeq files for GenomePaint paper

  RNASeq files for GenomePaint paper titled "Exploration of coding and non-coding variants in cancer using GenomePaint."

  Dataset EGAD00001006680

• RNASeq files for Roussel MBPRP

  RNASeq files for Roussel paper titled "Combination of CDK4/6 with BET-bromodomain and PI3K/mTOR inhibitors in medulloblastoma in vitro and in vivo"

  Dataset EGAD00001008842

• WES for Patient 9 to 14 of NIBIT-M4 clinical trial

  WES for Patient 9 to 14 of NIBIT-M4 clinical trial

  Dataset EGAD00001009700

• WGS files for CIC paper data

  WGS files for CIC paper titled "Malignant progression of an ancestral bone marrow clone harboring a CIC-NUTM2A fusion in isolated myeloid sarcoma"

  Dataset EGAD00001009787

• Shallow-whole genome sequencing for copy numbers in resectable gastric cancer treated with surgery alone

  Shallow-whole genome sequencing for copy numbers in resectable gastric cancer treated with surgery alone

  Dataset EGAD00001011994

• Project for Development of Innovative Research on Cancer Therapeutics;Shuttle system between petient-derived xenograft and ex vivo culture for innovative platform of evaluating drug sensitivity.

  We developed CTOS (cancer tissue-originated spheroid) panel covering diversity among patients for colorectal cancer, lung cancer and cervical small cell carcinoma. We then carried out exome sequence analysis of tumor tissues, cell lines and CTOS derived from patients to validate qualitative changes in preparation, culture, cell line, transplantation and passage of CTOS pathologically, biochemically, molecular biologically.

  Study JGAS000089

• Longitudinal therapy monitoring of ALK-positive non-small cell lung cancer (copy number, cell-free DNA)

  Clinical courses of non-small cell lung cancer patients with ALK rearrangements (ALK+ NSCLC) vary widely. We analyzed 271 longitudinal plasma samples from 73 patients with advanced ALK+ NSCLC treated with ALK tyrosine kinase inhibitors by combined hybrid-capture-based targeted sequencing (average 4,100x coverage) for mutation analysis and shallow whole genome sequencing (0.5x coverage) for global copy number profiling from cfDNA.

  Study EGAS00001004276

• Gene regulation of human stimulated and cultured CD4+ Treg cells

  This dataset maps gene expression regulation in human primary regulatory CD4+ T cells (Tregs) stimulated using PMA and ionomycin or cultured without stimulus for 18 hours. It includes whole genome sequence data for ChM-seq (18 H3K4me3, 20 H3K27ac and 3 inputs), ATAC-seq (42 samples) and whole transcriptome (39 samples). All individuals were genotyped using coreExome Illumina SNP chip array (included in EGAS00001003516).

  Study EGAS00001003515

• Host factors dictate gut microbiome alterations in chronic kidney disease more strongly than to kidney function

  Despite recent progress, microbial markers in Chronic Kidney Disease (CKD) remain inconclusive. We combined quantitative faecal metagenomics (N=130 CKD cohort) and cross-study biomarker comparisons (Ntotal=4420) to study microbiome associations with glomerular filtration rate (eGFR; kidney function) and 4-year CKD progression. Transit time (TT) and medications primarily explained microbiome variation, trumping eGFR-related effects. Metagenome analysis showed increased p-cresol and indole synthesis potential and decreased plant-to-animal CAZyme ratios with lower eGFR, coupled to a Bact1 to Rum enterotype shift, suggesting saccharolytic-to-proteolytic microbiome transitions linked to dietary guidelines and slowed-down TT. Peritoneal dialysis patients showed increased (dysbiotic) Bact2 prevalence and linked intestinal inflammation. Only Escherichia coli, an unnamed Alistipes species and Bifidobacterium adolescentis were confounder-independent markers for eGFR, but these nor previous markers convincingly replicated across 11 studies. No predictors for CKD progression were found. Together, poor evidence for microbiome biomarkers but substantial eGFR-independent effects were found, suggesting potential for nutritional and TT interventions in CKD.

  Study EGAS50000000646

• Scywalker: scalable end-to-end data analysis workflow for nanopore single-cell transcriptome sequencing

  Existing nanopore single-cell data analysis tools showed severe limitations in handling current data sizes. We developed novel scalable methods for cell barcode demultiplexing and single-cell isoform calling and quantification and incorporated these in an easily deployable package called scywalker.

  Study EGAS50000000537

• Breast implant-associated anaplastic large cell lymphoma shallow whole genome sequencing for copy number analysis and Whole exome sequencing data.

  Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) shallow whole genome sequencing of 29 BIA-ALCL patients for copy number analysis and 24 Alk-negative ALCL samples as control cohort. 7 Whole exome sequencing BIA-ALCL samples.

  Study EGAS00001003962

• BLUEPRINT September 2016, ChIP-Seq for thymocyte from thymus, on Genome GRCh38

  ChIP-Seq data for 5 sample(s) for thymocyte from thymus, on Genome GRCh38. 17 run(s), 17 experiment(s), 17 alignment(s). Part of BLUEPRINT (September 2016).Analysis documentation available at http://ftp.ebi.ac.uk/pub/databases/blueprint/releases/20140811/homo_sapiens/README_chipseq_analysis_ebi_20140811

  Dataset EGAD00001002947

• BLUEPRINT September 2016, ChIPmentation for regulatory T cell from venous blood, on Genome GRCh38

  ChIPmentation data for 2 sample(s) for regulatory T cell from venous blood, on Genome GRCh38. 14 run(s), 9 experiment(s), 9 alignment(s). Part of BLUEPRINT (September 2016).

  Dataset EGAD00001002942

• BLUEPRINT September 2016, ChIPmentation for conventional dendritic cell from cord blood, on Genome GRCh38

  ChIPmentation data for 1 sample(s) for conventional dendritic cell from cord blood, on Genome GRCh38. 4 run(s), 2 experiment(s), 2 alignment(s). Part of BLUEPRINT (September 2016).

  Dataset EGAD00001002940

• BLUEPRINT September 2016, ChIPmentation for naive B cell from tonsil, on Genome GRCh38

  ChIPmentation data for 1 sample(s) for naive B cell from tonsil, on Genome GRCh38. 1 run(s), 1 experiment(s), 1 alignment(s). Part of BLUEPRINT (September 2016).

  Dataset EGAD00001002937

• BLUEPRINT September 2016, ChIPmentation Acute Lymphocytic Leukemia for precursor B cell from venous blood, on Genome GRCh38

  ChIPmentation data for 5 sample(s) Acute Lymphocytic Leukemia for precursor B cell from venous blood, on Genome GRCh38. 7 run(s), 7 experiment(s), 7 alignment(s). Part of BLUEPRINT (September 2016).

  Dataset EGAD00001002936

• BLUEPRINT September 2016, ChIPmentation Acute Myeloid Leukemia for blast cell from bone marrow, on Genome GRCh38

  ChIPmentation data for 2 sample(s) Acute Myeloid Leukemia for blast cell from bone marrow, on Genome GRCh38. 12 run(s), 6 experiment(s), 6 alignment(s). Part of BLUEPRINT (September 2016).

  Dataset EGAD00001002935

• BLUEPRINT September 2016, ChIPmentation for germinal center B cell from tonsil, on Genome GRCh38

  ChIPmentation data for 1 sample(s) for germinal center B cell from tonsil, on Genome GRCh38. 1 run(s), 1 experiment(s), 1 alignment(s). Part of BLUEPRINT (September 2016).

  Dataset EGAD00001002932

• BLUEPRINT September 2016, ChIPmentation Acute Lymphocytic Leukemia for precursor B cell from bone marrow, on Genome GRCh38

  ChIPmentation data for 7 sample(s) Acute Lymphocytic Leukemia for precursor B cell from bone marrow, on Genome GRCh38. 13 run(s), 13 experiment(s), 13 alignment(s). Part of BLUEPRINT (September 2016).

  Dataset EGAD00001002928