14977 results for "cancer studies using rna-seq"

in 28.49 milliseconds.

• Reference epigenome Islet-derived-MSC02 miRNA-Seq data generated from KEP study

  Islet-derived-MSC02 miRNA-Seq single end data

  Dataset EGAD00001007182

• Reference epigenome SMC03 h3k4me3 ChIP-Seq data generated from KEP study

  SMC03 h3k4me3 ChIP-Seq paired end data

  Dataset EGAD00001007323

• Reference epigenome SMC09 input ChIP-Seq data generated from KEP study

  SMC09 input ChIP-Seq paired end data

  Dataset EGAD00001007355

• Reference epigenome SMC08 input ChIP-Seq data generated from KEP study

  SMC08 input ChIP-Seq paired end data

  Dataset EGAD00001007349

• Reference epigenome Islet-derived-MSC01 miRNA-Seq data generated from KEP study

  Islet-derived-MSC01 miRNA-Seq single end data

  Dataset EGAD00001007181

• Reference epigenome SMC01 h3k27ac ChIP-Seq data generated from KEP study

  SMC01 h3k27ac ChIP-Seq paired end data

  Dataset EGAD00001007308

• Reference epigenome SMC01 h3k4me1 ChIP-Seq data generated from KEP study

  SMC01 h3k4me1 ChIP-Seq paired end data

  Dataset EGAD00001007310

• Reference epigenome SMC01 input ChIP-Seq data generated from KEP study

  SMC01 input ChIP-Seq paired end data

  Dataset EGAD00001007313

• Reference epigenome ADMSC07 input ChIP-Seq data generated from KEP study

  ADMSC07 input ChIP-Seq paired end data

  Dataset EGAD00001007394

• Reference epigenome ADMSC08 h3k27Ac ChIP-Seq data generated from KEP study

  ADMSC08 h3k27Ac ChIP-Seq paired end data

  Dataset EGAD00001007395

• Reference epigenome SMC02 h3k4me3 ChIP-Seq data generated from KEP study

  SMC02 h3k4me3 ChIP-Seq paired end data

  Dataset EGAD00001007317

• Reference epigenome SMC02 h3k9me3 ChIP-Seq data generated from KEP study

  SMC02 h3k9me3 ChIP-Seq paired end data

  Dataset EGAD00001007318

• Reference epigenome ADMSC08 h3k27me3 ChIP-Seq data generated from KEP study

  ADMSC08 h3k27me3 ChIP-Seq paired end data

  Dataset EGAD00001007396

• Reference epigenome ADMSC08 h3k36me3 ChIP-Seq data generated from KEP study

  ADMSC08 h3k36me3 ChIP-Seq paired end data

  Dataset EGAD00001007397

• Reference epigenome ADMSC08 h3k4me3 ChIP-Seq data generated from KEP study

  ADMSC08 h3k4me3 ChIP-Seq paired end data

  Dataset EGAD00001007399

• Reference epigenome ADMSC08 h3k9me3 ChIP-Seq data generated from KEP study

  ADMSC08 h3k9me3 ChIP-Seq paired end data

  Dataset EGAD00001007400

• Reference epigenome SMC03 h3k27ac ChIP-Seq data generated from KEP study

  SMC03 h3k27ac ChIP-Seq paired end data

  Dataset EGAD00001007320

• Reference epigenome SMC03 h3k4me1 ChIP-Seq data generated from KEP study

  SMC03 h3k4me1 ChIP-Seq paired end data

  Dataset EGAD00001007322

• Reference epigenome SMC03 h3k36me3 ChIP-Seq data generated from KEP study

  SMC03 h3k36me3 ChIP-Seq paired end data

  Dataset EGAD00001007321

• Reference epigenome SMC04 h3k27ac ChIP-Seq data generated from KEP study

  SMC04 h3k27ac ChIP-Seq paired end data

  Dataset EGAD00001007326

• Reference epigenome SMC05 h3k27ac ChIP-Seq data generated from KEP study

  SMC05 h3k27ac ChIP-Seq paired end data

  Dataset EGAD00001007332

• Reference epigenome SMC05 h3k36me3 ChIP-Seq data generated from KEP study

  SMC05 h3k36me3 ChIP-Seq paired end data

  Dataset EGAD00001007333

• Reference epigenome SMC07 h3k27ac ChIP-Seq data generated from KEP study

  SMC07 h3k27ac ChIP-Seq paired end data

  Dataset EGAD00001007338

• Reference epigenome SMC05 input ChIP-Seq data generated from KEP study

  SMC05 input ChIP-Seq paired end data

  Dataset EGAD00001007337

• Reference epigenome SMC07 h3k4me1 ChIP-Seq data generated from KEP study

  SMC07 h3k4me1 ChIP-Seq paired end data

  Dataset EGAD00001007340

• Reference epigenome SMC07 h3k36me3 ChIP-Seq data generated from KEP study

  SMC07 h3k36me3 ChIP-Seq paired end data

  Dataset EGAD00001007339

• Reference epigenome SMC07 h3k4me3 ChIP-Seq data generated from KEP study

  SMC07 h3k4me3 ChIP-Seq paired end data

  Dataset EGAD00001007341

• Reference epigenome SMC07 h3k9me3 ChIP-Seq data generated from KEP study

  SMC07 h3k9me3 ChIP-Seq paired end data

  Dataset EGAD00001007342

• Reference epigenome SMC07 input ChIP-Seq data generated from KEP study

  SMC07 input ChIP-Seq paired end data

  Dataset EGAD00001007343

• Reference epigenome SMC08 h3k36me3 ChIP-Seq data generated from KEP study

  SMC08 h3k36me3 ChIP-Seq paired end data

  Dataset EGAD00001007345

• Reference epigenome SMC08 h3k4me3 ChIP-Seq data generated from KEP study

  SMC08 h3k4me3 ChIP-Seq paired end data

  Dataset EGAD00001007347

• Reference epigenome SMC08 h3k9me3 ChIP-Seq data generated from KEP study

  SMC08 h3k9me3 ChIP-Seq paired end data

  Dataset EGAD00001007348

• Reference epigenome ADMSC05 input ChIP-Seq data generated from KEP study

  ADMSC05 input ChIP-Seq paired end data

  Dataset EGAD00001007380

• Reference epigenome SMC09 h3k27ac ChIP-Seq data generated from KEP study

  SMC09 h3k27ac ChIP-Seq paired end data

  Dataset EGAD00001007350

• Reference epigenome SMC09 h3k4me1 ChIP-Seq data generated from KEP study

  SMC09 h3k4me1 ChIP-Seq paired end data

  Dataset EGAD00001007352

• Reference epigenome ADMSC01 h3k36me3 ChIP-Seq data generated from KEP study

  ADMSC01 h3k36me3 ChIP-Seq paired end data

  Dataset EGAD00001007357

• Reference epigenome ADMSC01 h3k4me1 ChIP-Seq data generated from KEP study

  ADMSC01 h3k4me1 ChIP-Seq paired end data

  Dataset EGAD00001007358

• Reference epigenome ADMSC01 h3k4me3 ChIP-Seq data generated from KEP study

  ADMSC01 h3k4me3 ChIP-Seq paired end data

  Dataset EGAD00001007359

• Reference epigenome ADMSC01 h3k9me3 ChIP-Seq data generated from KEP study

  ADMSC01 h3k9me3 ChIP-Seq paired end data

  Dataset EGAD00001007360

• Reference epigenome ADMSC05 h3k36me3 ChIP-Seq data generated from KEP study

  ADMSC05 h3k36me3 ChIP-Seq paired end data

  Dataset EGAD00001007376

• Reference epigenome ADMSC07 h3k36me3 ChIP-Seq data generated from KEP study

  ADMSC07 h3k36me3 ChIP-Seq paired end data

  Dataset EGAD00001007390

• Reference epigenome ADMSC07 h3k4me3 ChIP-Seq data generated from KEP study

  ADMSC07 h3k4me3 ChIP-Seq paired end data

  Dataset EGAD00001007392

• Reference epigenome ADMSC07 h3k9me3 ChIP-Seq data generated from KEP study

  ADMSC07 h3k9me3 ChIP-Seq paired end data

  Dataset EGAD00001007393

• Reference epigenome ADMSC08 input ChIP-Seq data generated from KEP study

  ADMSC08 input ChIP-Seq paired end data

  Dataset EGAD00001007401

• Reference epigenome SMC04 input ChIP-Seq data generated from KEP study

  SMC04 input ChIP-Seq paired end data

  Dataset EGAD00001007331

• Reference epigenome SMC09 h3k4me3 ChIP-Seq data generated from KEP study

  SMC09 h3k4me3 ChIP-Seq paired end data

  Dataset EGAD00001007353

• Reference epigenome SMC01 h3k36me3 ChIP-Seq data generated from KEP study

  SMC01 h3k36me3 ChIP-Seq paired end data

  Dataset EGAD00001007309

• Reference epigenome SMC02 h3k27ac ChIP-Seq data generated from KEP study

  SMC02 h3k27ac ChIP-Seq paired end data

  Dataset EGAD00001007314

• Reference epigenome SMC02 input ChIP-Seq data generated from KEP study

  SMC02 input ChIP-Seq paired end data

  Dataset EGAD00001007319

• Reference epigenome SMC09 h3k36me3 ChIP-Seq data generated from KEP study

  SMC09 h3k36me3 ChIP-Seq paired end data

  Dataset EGAD00001007351

• Reference epigenome SMC05 h3k4me3 ChIP-Seq data generated from KEP study

  SMC05 h3k4me3 ChIP-Seq paired end data

  Dataset EGAD00001007335

• Reference epigenome ADMSC02 h3k9me3 ChIP-Seq data generated from KEP study

  ADMSC02 h3k9me3 ChIP-Seq paired end data

  Dataset EGAD00001007366

• Reference epigenome ADMSC05 h3k4me1 ChIP-Seq data generated from KEP study

  ADMSC05 h3k4me1 ChIP-Seq paired end data

  Dataset EGAD00001007377

• Reference epigenome ADMSC06 h3k27Ac ChIP-Seq data generated from KEP study

  ADMSC06 h3k27Ac ChIP-Seq paired end data

  Dataset EGAD00001007381

• Reference epigenome ADMSC06 h3k4me1 ChIP-Seq data generated from KEP study

  ADMSC06 h3k4me1 ChIP-Seq paired end data

  Dataset EGAD00001007384

• Reference epigenome ADMSC07 h3k27Ac ChIP-Seq data generated from KEP study

  ADMSC07 h3k27Ac ChIP-Seq paired end data

  Dataset EGAD00001007388

• Reference epigenome ADMSC07 h3k27me3 ChIP-Seq data generated from KEP study

  ADMSC07 h3k27me3 ChIP-Seq paired end data

  Dataset EGAD00001007389

• Reference epigenome ADMSC06 h3k36me3 ChIP-Seq data generated from KEP study

  ADMSC06 h3k36me3 ChIP-Seq paired end data

  Dataset EGAD00001007383

• Reference epigenome SMC02_smRNA-Seq data generated from KEP study

  A SMC02_smRNA-Seq single end data for skeletal muscle cells

  Dataset EGAD00001003859

• Reference epigenome KNIH008 mRNA-seq data generated from KEP study

  A KNIH008 mRNA-seq paired end data for adipocytes

  Dataset EGAD00001002174

• Reference epigenome KNIH007 miRNA-seq data generated from KEP study

  A KNIH007 miRNA-seq single end data for adipocytes

  Dataset EGAD00001002766

• Reference epigenome KNIH008 miRNA-seq data generated from KEP study

  A KNIH008 miRNA-seq single end data for adipocytes

  Dataset EGAD00001002767

• Reference epigenome Islet-derived-MSC04 miRNA-Seq data generated from KEP study

  Islet-derived-MSC04 miRNA-Seq single end data

  Dataset EGAD00001007184

• Reference epigenome SMC03 input ChIP-Seq data generated from KEP study

  SMC03 input ChIP-Seq paired end data

  Dataset EGAD00001007325

• Reference epigenome SMC08 h3k4me1 ChIP-Seq data generated from KEP study

  SMC08 h3k4me1 ChIP-Seq paired end data

  Dataset EGAD00001007346

• Reference epigenome ADMSC02 input ChIP-Seq data generated from KEP study

  ADMSC02 input ChIP-Seq paired end data

  Dataset EGAD00001007367

• Reference epigenome ADMSC03 h3k27ac ChIP-Seq data generated from KEP study

  ADMSC03 h3k27ac ChIP-Seq paired end data

  Dataset EGAD00001007368

• Reference epigenome ADMSC03 h3k36me3 ChIP-Seq data generated from KEP study

  ADMSC03 h3k36me3 ChIP-Seq paired end data

  Dataset EGAD00001007369

• Reference epigenome ADMSC03 h3k4me1 ChIP-Seq data generated from KEP study

  ADMSC03 h3k4me1 ChIP-Seq paired end data

  Dataset EGAD00001007370

• Reference epigenome ADMSC03 h3k4me3 ChIP-Seq data generated from KEP study

  ADMSC03 h3k4me3 ChIP-Seq paired end data

  Dataset EGAD00001007371

• Reference epigenome ADMSC03 h3k9me3 ChIP-Seq data generated from KEP study

  ADMSC03 h3k9me3 ChIP-Seq paired end data

  Dataset EGAD00001007372

• Reference epigenome ADMSC03 input ChIP-Seq data generated from KEP study

  ADMSC03 input ChIP-Seq paired end data

  Dataset EGAD00001007373

• Reference epigenome ADMSC05 h3k27Ac ChIP-Seq data generated from KEP study

  ADMSC05 h3k27Ac ChIP-Seq paired end data

  Dataset EGAD00001007374

• Exome and RNA sequencing of Greenlanders

  This study contains whole exome sequence of 27 Greenlanders and deep RNA sequencing of 17 Greenlanders

  Study EGAS00001002727

• Total RNA sequencing of RNA from testicular tissue

  Study EGAS00001006119

• Genetic and Hormonal Contributions to Gene Expression in Immune Cells

  The origins of sex differences in human disease are elusive, in part because of difficulties in separating the effects of sex hormones and sex chromosomes. To isolate the effects of testosterone, estradiol, and sex chromosome complement (XX or XY) in humans, we implemented a four-state, cross-sectional study design of trans- and cisgender individuals, the former receiving exogenous testosterone or estradiol for at least a year as part of their gender-affirming medical care. This study design allowed us to compare four combinations of sex hormones and sex chromosomes in humans: XX individuals treated with exogenous testosterone (n=21), XY individuals treated with exogenous estradiol (n=13), untreated XX individuals (n=20), and untreated XY individuals (n=15). We chose to focus on the human immune system because it displays an impressively broad range of sex-differential biology. We collected blood samples from each individual and isolated PBMCs the same day. We performed 10X Genomics 3' single-cell RNA-sequencing (scRNA-seq) on PBMCs from the 69 individuals. We generated 150-bp paired end reads from a total of 358,426 cells (with an average of 48,007 reads/cell) and identified 18 distinct immune cell types. We found that testosterone, estradiol, and sex chromosome complement have unique, non-overlapping effects on PBMC cell abundances and gene expression.

  Study phs003860

• A Perioperative Study of Safusidenib in Patients with IDH1-Mutated Glioma

  10 participants with a radiological or pathological diagnosis of WHO Grade 2 lower-grade glioma (LGG) were recruited at a single center starting in December, 2022. Eligibility criteria permitted participants who had undergone prior surgery for WHO Grade 2 LGG, but excluded those with a history of prior radiation or chemotherapy.In Part A of the study, participants underwent an initial craniotomy with tumor biopsy and a lumbar puncture for cerebrospinal fluid (CSF) collection at study entry. Following sample collection, participants received safusidenib at the recommended phase 2 doses of 250 mg twice daily (b.i.d.) for a period of 22–36 days. This was followed by a second craniotomy for maximal safe tumor resection and a repeat lumbar puncture within 5 hours of the final pre-resection dose of safusidenib. Tumor, blood, and CSF samples were collected at both surgical time points for comprehensive translational research.Molecular analyses were performed on samples collected at both time points. These included pharmacokinetics (PK), targeted metabolomics, whole-genome sequencing (WGS) of tumor tissue, single-nucleus RNA sequencing (snRNA-seq), and DNA methylation profiling on all patients. Targeted metabolomics was conducted on samples from 9 participants, while spatial transcriptomics and spatial metabolomics were performed on tumor tissue from 3 participants each. Histone methylation profiling was conducted on samples from 8 participants.

  Study phs003976

• Symptom Clusters in Oncology Patients Receiving Chemotherapy

  The parent longitudinal study evaluated the symptom experience of oncology outpatients receiving chemotherapy. Patients completed questionnaires in their homes a total of six times (assessments 1 through 6). The questionnaires were timed to evaluate symptoms associated with the receipt of two cycles of chemotherapy that were administered approximately a month apart. Assessments 1 and 4 evaluated symptoms prior to the receipt of chemotherapy. Assessments 2 and 5 evaluated symptoms in the week following the administration of chemotherapy. Assessments 3 and 6 evaluated symptoms two weeks following the administration of chemotherapy. For this analysis, morning and evening fatigue data from the enrollment assessment (i.e., prior to the second or third cycle of chemotherapy) and the assessment that was done approximately 1 week after administration of chemotherapy were evaluated. Patients completed the Lee Fatigue Scale to obtain information on morning and evening fatigue severity. For the morning fatigue assessment, patients were asked to describe how they “felt over the past week when they woke up in the morning”. For the evening fatigue assessment, they were asked to describe how they felt over the past week “before they went to bed at night”. Medical records were reviewed for disease and treatment information. Epigenome assays (microarray) were completed for 1170 patients. Whole transcriptome sequencing (bulk RNA-Seq) was completed for 651 patients.

  Study phs003863

• ICGC MMML-seq Data Freeze March 2013 transcriptome sequencing

  ICGC MMML-seq Data Freeze March 2013 transcriptome sequencing

  Dataset EGAD00001000356

• Reference epigenome KNIH005 mRNA-seq data generated from KEP study

  A KNIH005 mRNA-seq paired end data for islet cells

  Dataset EGAD00001002171

• Reference epigenome Islet-derived-iPSC02 mRNA-Seq data generated from KEP study

  Islet-derived-iPSC02 mRNA-Seq paired end data

  Dataset EGAD00001007165

• Reference epigenome KNIH001 miRNA-seq data generated from KEP study

  A KNIH001 miRNA-seq single end data for islet cells

  Dataset EGAD00001002760

• ATAC-Seq of human stimulated and cultured CD4+ Treg cells

  This dataset includes whole genome sequence data for ATAC-seq (42 samples) of human stimulated and cultured CD4+ Treg cells.

  Dataset EGAD00001004829

• Reference epigenome IPS02_N_NPC_mRNA-Seq data generated from KEP study

  A IPS02_N_NPC_mRNA-Seq paired end data for Neural progenitor cells(Nestin)

  Dataset EGAD00001003489

• Reference epigenome IPS02_N_NPC_smRNA-Seq data generated from KEP study

  A IPS02_N_NPC_smRNA-Seq single end data for Neural progenitor cells(Nestin)

  Dataset EGAD00001003502

• Reference epigenome IPS03_N_ENeuron_smRNA-Seq data generated from KEP study

  A IPS03_N_ENeuron_smRNA-Seq single end data for Early neuron cells(Tuj1)

  Dataset EGAD00001003503

• Reference epigenome KNIH001 mRNA-seq data generated from KEP study

  A KNIH001 mRNA-seq paired end data for islet cells

  Dataset EGAD00001002167

• McGill EMC Release 4 for assay "smRNA-seq"

  McGill EMC Release 4 for assay "smRNA-seq": Transcriptome profiling by high-throughput sequencing

  Dataset EGAD00001001292

• Reference epigenome IPS05_X_NPC_mRNA-Seq data generated from KEP study

  A IPS05_X_NPC_mRNA-Seq paired end data for Neural progenitor cells(Nestin)

  Dataset EGAD00001003492

• Oxford Human islet ATAC-seq dataset of 5 human islets

  ATAC-seq data for 5 non-diabetic human pancreatic islet samples

  Dataset EGAD00001003759

• Reference epigenome Pancreas-Islet02 h3k36me3 ChIP-Seq data generated from KEP study

  Pancreas-Islet02 h3k36me3 ChIP-Seq paired end data

  Dataset EGAD00001007195

• Reference epigenome IPS-Fibroblast02 input ChIP-Seq data generated from KEP study

  IPS-Fibroblast02 input ChIP-Seq paired end data

  Dataset EGAD00001007276

• McGill EMC Release 4 for assay "Bisulfite-seq"

  McGill EMC Release 4 for assay "Bisulfite-seq": Methylation profiling by high-throughput sequencing

  Dataset EGAD00001001289

• Reference epigenome KNIH002 mRNA-seq data generated from KEP study

  A KNIH002 mRNA-seq paired end data for islet cells

  Dataset EGAD00001002168

• Reference epigenome KNIH003 mRNA-seq data generated from KEP study

  A KNIH003 mRNA-seq paired end data for islet cells

  Dataset EGAD00001002169

• Reference epigenome IPS06_X_ENeuron_mRNA-Seq data generated from KEP study

  A IPS06_X_ENeuron_mRNA-Seq paired end data for Early neuron cells(Tuj1)

  Dataset EGAD00001003493

• Reference epigenome KNIH005 miRNA-seq data generated from KEP study

  A KNIH005 miRNA-seq single end data for islet cells

  Dataset EGAD00001002764

• Reference epigenome KNIH004 miRNA-seq data generated from KEP study

  A KNIH004 miRNA-seq single end data for islet cells

  Dataset EGAD00001002763

• Reference epigenome KNIH002 miRNA-seq data generated from KEP study

  A KNIH002 miRNA-seq single end data for islet cells

  Dataset EGAD00001002761

• Reference epigenome KNIH003 miRNA-seq data generated from KEP study

  A KNIH003 miRNA-seq single end data for islet cells

  Dataset EGAD00001002762