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• STAG1 and STAG2-ChIP-seq in RAD21-mutant adult acute myeloid leukemia

  STAG1 and STAG2-ChIP-seq in RAD21-mutant adult acute myeloid leukemia

  Dataset EGAD00001015361

• Single-cell RNA-seq of PBMC from 2 patients iGRAN-Low and 2 patients iGRAN-High

  Single-cell RNA-seq of PBMC from 2 patients iGRAN-Low and 2 patients iGRAN-High [Publication title] CXCL8 secreted by immature granulocytes inhibits wildtype hematopoiesis in chronic myelomonocytic leukemia

  Study EGAS50000000556

• Enhanced reduced representation bisulfite sequencing (eRRBS) on 45 multiple myeloma samples and 3 normal plasma cell

  Enhanced reduced representation bisulfite sequencing (eRRBS) on 45 multiple myeloma samples and 3 normal plasma cell. Libraries were sequenced on a HiSeqTM4000 Illumina machine using 75bp paired-end reads

  Study EGAS00001004348

• Multi-omics profiling identifies two epithelioid sarcoma molecular subtypes with distinct signaling and immune characteristics

  Bulk RNA Sequencing of 33 epithelioid sarcomas (EpS) and 3 extracranial extra-renal rhabdoid tumors (EERT) Whole-exome sequencing of 30 EpS and 3 EERT Single-cell RNA Sequencing of 8 EpS Visium Spatial Transcriptomics of 3 EpS

  Dataset EGAD50000001419

• scRNAseq and scTCRseq data from tumor-infiltrating lymphocytes

  SCRNAseq and TCRseq are performed using 10X genomics technology on lymphocytes from tumor of 8 individuals (4 different conditions and 2 replicates per condition): - ISO : isotype sample_1 - ISO_dup :isotype sample_2 aPD1 : sample anti-PD1_1 aPD1_dup :sample anti-PD1_2 aCTLA4: sample anti-CTLA4_1 aCTLA4_dup :sample anti-CTLA4_2 combo : sample_anti-PD1_anti-CTLA4_1 combo_dup : sample_anti-PD1_anti-CTLA4_2

  Dataset EGAD50000001214

• Single-cell RNA sequencing on 5063 single T cells from six hepatocellular carcinoma patients

  T cells isolated from peripheral blood, tumors and adjacent normal tissues from six hepatocellular carcinoma patients. SmartSeq2 and Tang2009 protocol were used to amplify RNA from single T cells. High depth enables simultaneously expression profiling and TCR assembling.

  Dataset EGAD00001003337

• Epigenetic profiling of colorectal cancer initiating cells (CC-ICs) and investigation of changes in transcriptome following EZH2 inhibition using RNA-seq.

  Epigenetic profiling of colorectal cancer initiating cells (CC-ICs) to identify bivalently marked genes (H3K4me3 and H3K27me3 ChIP-seq), and investigation of changes in transcriptome following EZH2 inhibition using RNA-seq.

  Dataset EGAD00001004133

• Circulating tumour DNA abundance and potential utility in de novo metastatic prostate cancer

  We set out to determine ctDNA abundance at de novo mCSPC diagnosis and whether ctDNA provides complementary clinically relevant information to a prostate biopsy. We collected and sequenced 77 plasma cell-free DNA samples from 53 newly diagnosed patients with mCSPC. Targeted sequencing was also performed on DNA from 48 diagnostic prostate tissue samples.

  Dataset EGAD00001004526

• Whole-exome sequencing of matched blood, primary GBM tumours, and patient-derived organoids

  Whole-exome sequencing (~250X coverage) of primary GBM tumours and matched patient-derived organoids and normal blood. Samples from two spatially distinct regions of seven tumours from five patients (five primary, two recurrent).

  Dataset EGAD00001007935

• Single cell atlas of human glioma

  We profiled 87 primary-recurrentpatient-matched paired GBM specimens with single-nucleus RNA and bulk-DNA sequencing and single-cell open-chromatin and spatial transcriptomics/proteomics assays. We found that recurrent GBMs are characterized by a shift to a mesenchymal phenotype in response to therapy

  Dataset EGAD00001008811

• lymphoma plasma cfRNA

  Dataset contains total RNA sequencing data from plasma of 65 different human donors: 30 diffuse large B-cell lymphoma (DLBCL) and 13 primary mediastinal large B-cell lymphoma (PMBCL) patients, and 22 cancer-free controls. Samples were sequenced on a NovaSeq 6000 and are provided in FASTQ format.

  Dataset EGAD00001010259

• Dr. Fatima Mechta-Grigoriou, PhD, DR1 Head of Stress and Cancer Laboratory Deputy Director Genetic and Biology of Cancer Dpt Institut Curie - Inserm U830

  Dac EGAC00001000581

• Exome_NanoSeq__Thyroid_

  Exome NanoSeq in thyroid from a number of donors, both healthy and with pathology.

  Study EGAS00001007175

• Targeted_NanoSeq___Thyroid

  Targeted NanoSeq in thyroid from a number of donors, both healthy and with pathology.

  Study EGAS00001007647

• Clonal IGHV rearrangements in IGH+ and IGHUND HGBCL-DH-BCL2(-BCL6)

  PCR-based VDJ profiling in IGH+ and IGHUND HGBCL-DH-BCL2(-BCL6) lymphomas

  Dataset EGAD50000001523

• WGS of 8 trios - affected child and both normal parents

  WGS of 8 trios - affected child and both normal parents

  Dataset EGAD00001001467

• RNA-Seq of human stimulated and cultured CD4+ Treg cells

  This dataset includes whole transcriptome data of human stimulated and cultured CD4+ Treg cells (39 samples).

  Dataset EGAD00001005964

• Tissue-specific cell-free DNA degradation quantifies circulating tumor DNA burden

  Profiling of circulating tumor DNA (ctDNA) may offer a non-invasive approach to monitor disease progression. Here, we developed a quantitative method, exploiting local tissue-specific cell-free DNA (cfDNA) degradation patterns, that accurately estimates ctDNA burden independent of genomic aberrations. Nucleosome-dependent cfDNA degradation at promoters and first exon-intron junctions was strongly associated with differential transcriptional activity in tumors and blood. A quantitative model, based on just 6 regulatory regions, could accurately predict ctDNA levels in colorectal cancer patients. Strikingly, a model restricted to blood-specific regulatory regions could predict ctDNA levels across both colorectal and breast cancer patients.

  Study EGAS00001004657

• The Nordic Centre of Excellence Programme in Molecular Medicine Data Access Committee

  Dac EGAC00000000006

• Novel de novo pathogenic variant in the GNAI1 as a cause of severe disorders of intellectual development with autistic features

  Study EGAS00001005346

• A cycling, progenitor-like cell population at the root of atypical teratoid rhabdoid tumor subtype differentiation trajectories

  Study EGAS00001008123

• Novel de novo pathogenic variant in the GNAI1 as a cause of severe disorders of intellectual development with autistic features

  Study EGAS00001005355

• 500FG DNA methylation data

  This dataset contains the DNA methylation data of 260 samples from Dutch healthy individuals.

  Dataset EGAD00010002769

• Mexican_Biobank_Genotypes

  Samples from the Mexican Biobank

  Dataset EGAD00010002361

• EGAD00010000518

  Samples from the Greek island of Crete, MANOLIS cohort

  Dataset EGAD00010000518