16787 results for "sec+and+unspecified+malignant+neoplasm"

in 25.34 milliseconds.

• Sexual dimorphism AR RNASeq

  Human (n=34) and mice (n=68) melanoma tumor WXS dataset.

  Dataset EGAD00001008708

• Whole genome sequencing of a breast cancer cohort with known functional homologous recombination status

  41 breast cancer patients with known functional homologous recombination status (matched normal and tumor genomes, n=82)

  Dataset EGAD00001008027

• NKI PRECSION Mutations

  38 samples with DCIS and matched recurrences sequenced with a targeted mutation panel on IonTorrent.

  Dataset EGAD00001008338

• Whole exome sequencing of serially sampled TNBC patients on pre/on PARP inhibitor

  Novaseq whole exome raw sequence files (FastQ) for breast cancer tumor core biopsies and blood normal control.

  Dataset EGAD00001007916

• MTM-HD - fibroblast RNAseq

  MTM-HD - fibroblast RNAseq. 57 samples from controls, pre-HD and early-HD patients.

  Dataset EGAD00001009104

• MTM-HD - adipose tissue RNAseq

  MTM-HD - adipose tissue RNAseq. 60 samples from controls, pre-HD and early-HD patients

  Dataset EGAD00001009105

• KUI6280

  RNA seq data normal and hypomethylation

  Dataset EGAD00001009887

• RNA-seq data for HCC patients from Y90+Nivolumab trial

  This dataset includes RNA-seq fastq files of pre-treatment and on-treatment samples from 28 patients

  Dataset EGAD00001010132

• Proteomics of 7-member healthy family (father, mother, their three biological daughters and monozygotic twin sons)

  The dataset contains proteomics data of seven healthy family members. The samples were taken from peripheral blood mononuclear cells.

  Dataset EGAD00001009985

• Spatial TCR sequencing in breast cancer

  Spatial characterization by TCR sequencing in tumor core and matched stroma in seven cases of triple negative breast cancer.

  Dataset EGAD00001010203

• PRMS transcriptomes

  Transcriptome sequencing of three normal skeletal muscle and 15 pleomorphic rhabdomyosarcoma patient tumors.

  Dataset EGAD00001010915

• CHEWIE ctDNA in Rhabdomyosarcoma

  Targeted DNA based panel of multiple ctDNA samples from 10 patients througout clinical care to assess treatment response. The panel is custom-designed and property of UGS, IC.

  Dataset EGAD00001011127

• RNA-sequencing of cohesin-mutated and wildtype adult AMLs

  Transcriptomic data generated by RNA-sequencing for adult human AMLs with STAG2 or RAD21 mutations or no cohesin mutations (CTRL-AMLs).

  Dataset EGAD00001011197

• Optimizing single-cell transcriptomic discrimination of atopic dermatitis versus psoriasis vulgaris

  AD Samples 1 and 2. AD1 has 2 runs of additional sequencing, AD2 has 1 run of additional sequencing.

  Dataset EGAD00001011286

• Whole genome sequencing of 78 follicular lymphoma tumours and matched normals

  Whole genome sequencing for tumour/normal matched pairs from 78 samples

  Dataset EGAD00001011343

• TCRab sequencing of CML patients

  This dataset contains 15 TCRab sequencing samples from 6 CML patients before and after TKI-cessation. The raw data is available as fastq files.

  Dataset EGAD00001012841

• Multidimensional and Longitudinal Immune Profiling of Sepsis in Uganda

  We conducted a prospective, observational cohort study of adults (RESERVE-U-2-TOR) admitted to Tororo General Hospital in eastern Uganda with severe, undifferentiated infection (i.e., suspected sepsis). Briefly, whole-blood samples were collected in PAXgene blood RNA tubes (PreAnalytiX, Qiagen, Germantown, MD, USA), from which RNA was extracted using PAXgene Blood RNA Kits (cat. no. 762164) (Qiagen). Sequencing libraries were constructed with the NEBNext Ultra II RNA Library Preparation Kit for Illumina, after which libraries were multiplexed and sequenced on the Illumina NovaSeq X Plus platform (Illumina, Inc, San Diego, CA). Data from this study available through dbGaP include raw RNA-Seq data generated from whole-blood samples collected upon RESERVE-U-2-TOR study enrollment (N=274).

  Study phs003914

• Targeting PTPRK-RSPO3 colon tumours promotesdifferentiation and loss of stem-cell function

  Colorectal cancer remains a major unmet medical need, promptinglarge-scale genomics efforts in the field to identify moleculardrivers for which targeted therapies might be developed. Wepreviously reported the identification of recurrent translocationsin R-spondin proteins present in a subset of colorectal tumours.Here we show that targeting RSPO3 in PTPRK-RSPO3-fusion positivehuman tumour xenografts inhibits tumour growth andpromotes differentiation. Notably, genes expressed in the stem-cellcompartment of the intestine were among those most sensitive toanti-RSPO3 treatment. This observation, combined with functionalassays, suggests that a stem-cell compartment drives PTPRK-RSPO3colorectal tumour growth and indicates that the therapeutictargeting of stem-cell properties within tumours may be a clinicallyrelevant approach for the treatment of colorectal tumors.

  Study EGAS00001001462

• Molecular profiling of tissue autopsies and ctDNA

  The dataset contains high-throughput sequencing data derived from a cancer autopsy series of 10 patients. As part of this study, whole-exome sequencing and RNA-seq were performed for spatially distinct tissue biopsies from the patients. In addition, plasma samples from the patients were sequenced using a custom panelt to profile ctDNA. There are 106 files containing whole-exome sequencing data, 107 files containing RNA-seq data, and 9 files containing plasma sequencing data.

  Dataset EGAD00001007040

• Human Heredity and Health in Africa Data Access Committee

  Dac EGAC00001000648

• DAC for lymphoma IFZ Essen

  This DAC is set in place to handle acess to data on lymphomas and immune cells submitted by scientists from the Institute of Cell Biology (Cancer Research) at the University of Duisburg-Essen in Essen, Germany.

  Dac EGAC50000000521

• Heritable pulmonary arterial hypertension - new genetic findings and environmental triggers

  This dataset contains whole exome sequencing data of 13 family members of 5 heritable pulmonary arterial hypertension families.

  Dataset EGAD50000001817

• WGBS of stepwise-edited melanoma model

  This dataset contains WGBS of a stepwise-edited, human melanoma model including in vitro samples and corresponding xenografts.

  Dataset EGAD50000001317

• HRR gene mutation analysis

  Mutation analysis of cfDNA from urine (stored at various storage conditions) and plasma using the QIAseq HRR panel

  Dataset EGAD50000001586

• Primary human hepatocyte ATAC-seq

  Profiling the chromatin accessibility landscape of cultured primary human hepatocytes (PHH) from three female and three male adult, non-diabetic donors.

  Dataset EGAD50000001751