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Sequencing of pancreatic cancer primary tumors and metastases
Study
EGAS00001002186
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Lindsey E. Jones et al. Patient-derived cells from recurrent tumors that model the evolution of IDH-mutant glioma. Neuro-Oncology Advances, 2020. We established robust, versatile, and well-characterized Patient Derived Cells (PDC) of an IDH1-mutant astrocytoma and an IDH1-mutant oligodendroglioma that represents defined evolutionary stages of chemotherapy-induced hypermutation. The PDCs retain tumor subtype defining features over time as well as classic hallmarks of cancer, including anchorage independent growth and cell immortality. The integrated phylogenies composed of PDCs,single-cell-derived PDCs, patient-derived xenografts, and corresponding spatiotemporal tumor tissue samples also provide new insight into the clonality, evolutionary pattern, and immense mutational load of hypermutated IDH mutant gliomas.
Study
EGAS00001003992
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Drug screening and whole genome sequencing of primary cells and cell lines from ovarian cancer patients to associate genomic aberrations with in vitro drug sensitivities
Study
EGAS00001002239
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Osteosarcoma_Whole_Genome
Study
EGAS00001000147
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Exomes of High-risk Prostate cancer
Study
EGAS00001001015
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Poly(A) RNA sequencing of hepatocellular carcinoma tumors and their matched noncancerous liver tissues
Study
EGAS00001002337
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1 Intratumoral genetic heterogeneity and clonal evolution following neoadjuvant chemoradiotherapy (nCRT) in locally advanced rectal tumors.
Study
EGAS00001003250
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Metastatic_Prostate_Follow_Up
Study
EGAS00001000730
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A Study to Evaluate Denosumab in Young Patients With Primary Breast Cancer (D-Beyond)
Study
EGAS00001003252
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Metastatic_Prostate_Follow_Up_2
Study
EGAS00001000756