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• Department of Gastroenterology and Hepatology Data Access Committee

  Dac EGAC00001003021

• Single-Cell NSC DAC – ADHD and Control iPSC Study

  Dac EGAC00001003572

• Walter and Eliza Hall Institute Research Data Access Committee

  Dac EGAC00001003583

• LUMC Department Cell and Chemistry Biology, Diabetes Group

  Dac EGAC50000000905

• A Pilot Study of NKTR-214 and Nivolumab in Selected Patients with Locally Advanced/Metastatic Sarcoma

  Study cohort comprises samples derived from patients that received treatment on an open-label, non-randomized, non-comparative pilot study of bempegaldesleukin, a CD122-preferential interleukin-2 pathway agonist, with nivolumab in refractory sarcoma at Memorial Sloan Kettering/MD Anderson Cancer Centers (NCT03282344). Patient tumors include a variety of sarcoma subtypes. Samples include whole exome sequencing of tumor/normal pairs, poly-A RNA and TCR sequencing of tumors.

  Study phs002852

• Whole genome sequencing data of paediatric ETV6-RUNX1 acute lymphoblastic leukemia

  Whole genome sequencing data from paediatric (<18-y) ETV6-RUNX1 fusion positive acute lymphoblastic leukemias. Dataset includes fastq and BAM files from diagnostic and remission (control) samples of 33 patients. Dataset consists of two experiments depending on sequencing instrument; "Experiment 1" sequenced by using Illumina Hiseq X Ten instrument, and "Experiment 2" Illumina Novaseq 6000, respectively.

  Dataset EGAD00001010128

• CML-SC and HSC study data access committee

  Dac EGAC00001003028

• European Network of Genomic and Genetic Epidemiology Data Access Committee

  Dac EGAC00000000008

• Molecular and Population Genetics (MPG) research at ICR DAC

  Dac EGAC00001000304

• JDRF/Wellcome Diabetes and Inflammation Laboratory Data Access Committee

  Dac EGAC00001000756

• UT MD Anderson Cancer Center Genomic Medicine and Leukemia

  Dac EGAC00001001252

• Transcriptomics of CD8 T cells and Immune Checkpoint Blockade

  Dac EGAC00001001482

• Genetics and transcriptomics of human acute erythroid leukemia

  Dac EGAC00001001553

• Mapping of mtDNA deletions and duplications Data Access Committe

  Dac EGAC00001001558

• Princess Margaret Head and Neck Cancer Data Access Committee

  Dac EGAC00001001647

• Imperial College Tumour Immunology group - Surgery and Cancer DAC

  Dac EGAC00001001814

• Short and long-read sequencing of Brugada syndrome samples

  Dac EGAC00001001908

• DAC Whole-Exome Sequences Tunisian Imazighen and non-Imazighen

  Dac EGAC00001002064

• MRC Institute of Genetics and Cancer Data Access Committee

  Dac EGAC00001002163

• Germline RUNX1 Variation and Predisposition to Childhood Acute Lymphoblastic

  Dac EGAC00001002180

• Kutanan and Liu et al 2021 Thai study DAC

  Dac EGAC00001002553

• Southeast Asia and Oceania: Affymetrix 6.0 array genotype data

  Dac EGAC00001002594

• CML DAC commitee by GIS and Duke-NUS

  Dac EGAC00001002245

• "IL-17A-Producing ILC3s and Duodenal Adenoma in FAP"

  Dac EGAC00001003301

• IDH mutant Glioma methylation analysis and prognostic signatures

  Study EGAS00001006961

• Common and rare germline variants in Japanese prostate cancer patients

  Study JGAS000487

• Single nuclei sequencing data from Schizophrenia and control PFC

  Dac EGAC50000000742

• WXS Tumor Samples Javelin head and neck 100

  Study EGAS00001007583

• WXS Normal Samples Javelin head and neck 100

  Study EGAS00001007526

• JAK and STAT alterations in CD30 positive LPD

  Study EGAS00001004181

• Human primary and metastatic colorectal cancer (CRC) samples

  Study EGAS00001006746

• Phenotype_files

  Description of phenotype and data dictionary

  Dataset EGAD00010002695

• Investigation of Human DNA Replication Timing Variation by Whole Genome Sequencing

  To study inter-individual variation in human DNA replication timing, we performed whole-genome sequencing of human pluripotent stem cell lines. This data was used to infer replication timing and link them to genetic polymorphisms.

  Study phs001957

• Genomic Profiling Reveals Heterogeneous Populations of Ductal Carcinoma In Situ

  Whole Exome Sequencing(WES) and copy number variation(CNV) analysis were performed using breast samples collected from non-invasive breast cancer patients in order to analysis of somatic mutations related to breast tumor phenotypes.

  Study JGAS000202

• WGS of IPMN-PDAC Data

  This study investigates IPMN-PDAC development using whole-genome sequencing (WGS) data from 42 tumours collected from multiple regions and 12 matched normal samples. Sequencing was performed on Illumina platforms with 150 bp paired-end reads.

  Study EGAS50000001182

• MEMORI WES bams

  This project stores bam files from deep whole exome sequencing from oesophageal adenocarcinoma at different timepoints during neoadjuvant treatment (prior, during, post treatment), which were used to analyse evolutionary and phenotype dynamics in oesophageal adenocarcinoma during neoadjuvant treatment.

  Study EGAS50000000240

• Longitudinal evaluation of circulating tumor DNA in early breast cancer receiving neoadjuvant systemic therapy using a tumor-informed assay

  This study evaluates a highly sensitive tumor-informed ctDNA assay in a real-world cohort of patients receiving neoadjuvant therapy (NAT) to assess clinical validity and explores prognostic outcomes

  Study EGAS50000000771

• Predictors of Immune Checkpoint Blockade Response in dMMR Colorectal Cancer Using an Integrated Immune-Enhanced Multi-Omics Platform

  To identify candidate tumor- and immune-related biomarkers associated with clinical outcomes following anti–PD-1 therapy in dMMR colorectal cancer, we conducted a comprehensive genomic profiling using ImmunoID NeXT platform, including whole exome, whole transcriptome and TCR/BCR sequencing.

  Dataset EGAD50000002504

• Oxidative DNA damage and ubiquitin proteasome system dysfunction underpins neurodegeneration in young adults with a DNA repair disorder

  Deposited here are time series bulk RNA-seq data generated from isogenic wild-type (WT), XPA and XPG gene knockouts hiPSC cells during cortical neuronal differentiation.

  Dataset EGAD50000000228

• Oxidative DNA damage and ubiquitin proteasome system dysfunction underpins neurodegeneration in young adults with a DNA repair disorder

  Deposited here are time series bulk RNA-seq data generated from XP patients and controls as well as rescued patient hiPSC cells during cortical neuronal differentiation.

  Dataset EGAD50000000230

• Lung_Multi_site_Targeted_Sequence_Capture

  DNA extracted from multiple biopsies taken from different areas of primary lung tumours will be subjected to targeted re-sequencing and analysed in order to assess intra-tumour heterogeneity with respect to mutations in a selection of cancer related genes.

  Study EGAS00001000436

• Multisite_Primary_Breast_Cancer

  DNA extracted from multiple biopsies taken from different areas of primary breast tumours will be subjected to targeted re-sequencing and analysed in order to assess intra-tumour heterogeneity with respect to mutations in a selection of cancer related genes.

  Study EGAS00001000891

• Whole genome sequencing data of 15 French Caucasian and 10 African-Caribbean men with prostate Cancer.

  Whole genome sequencing data of 15 French Caucasian and 10 African-Caribbean men with prostate Cancer.

  Dataset EGAD00001003115

• DDD DATAFREEZE 2016-10-03: 7832 trios - phenotypic and family descriptions

  DDD DATAFREEZE 2016-10-03: 7831 trios - phenotypic and family descriptions

  Dataset EGAD00001003350

• DDD DATAFREEZE 2014-11-04: 4293 trios - phenotypic and family descriptions

  DDD DATAFREEZE 2014-11-04: 4293 trios - phenotypic and family descriptions

  Dataset EGAD00001001977

• Whole-Exome Sequences Tunisian Imazighen and non-Imazighen

  Dataset with 55 whole-exome sequences from Tunisian non-Imazighen samples and 20 whole-exome sequences from Tunisian Imazighen samples.

  Dataset EGAD00001007511

• Newcastle COVID-19 Single-cell PBMC

  Single-cell multi-omic profiling of healthy controls, asymptomatic and hosptial-admitted COVID19 patients recruited from Newcastle University hospitals. These data also include healthy control volunteers treated with IV-LPS as inflammatory controls. Data represent RNA-seq, surface protein measurements (CITE-seq) of 192 antibody targets, along with VDJ-seq profiling of single T cell and B cell receptors.

  Dataset EGAD00001007866

• Whole genome sequencing of brain AVM endothelial and non-endothelial cell fractions

  Whole genome sequencing data of brain AVM endothelial and non-endothelial cell fractions, as well as paired blood samples

  Dataset EGAD00001009696

• Transcriptome profiling of human lung fibroblasts in COPD

  Primary lung fibroblast were isolated from well-matched control donors (no COPD, n=3) and patients with COPD (GOLD stage I-IV, n=8). Total RNA of cultured human lung fibroblast were isolated at passage 3 and rRNA was depleted. 75 bp single-end reads were generated from RNA libraries on Illumina NextSeq 500.

  Dataset EGAD00001009405

• H3K27ac ChIP-seq of human acute leukemias and healthy donors

  H3K27ac ChIP-seq of 79 primary samples derived from human acute leukemias, namely AML, T-ALL and mixed myeloid/lymphoid leukemias with CpG Island Methylator Phenotype (CIMP). In addition, 4 samples derived from CD34+ cord blood cells of healthy donors were included.

  Dataset EGAD00001011060