13397 results for ""60+mice"+"6+weeks"+diet+study+2014+2017+DOI"

in 20.28 milliseconds.

• Elucidation of the association between viruses and autoimmune diseases and COVID-19

  We determined the presence of endogenous human herpesvirus 6 (eHHV-6) and calculated anellovirus load from whole-genome sequencing data of 1,164 patients with COVID-19.

  Study JGAS000739

• RNA-sequencing of ex situ stimulated donors blood cells

  Cells from whole blood stimulation assay were cryopreserved. The cryopreserved cells were thawed and subjected to RNA preparation. RNA obtained were subjected to for bulk sequencing.

  Study EGAS50000001077

• ABHD11 Autoimmunity Study DAC

  This DAC oversees controlled access to human RNA-seq data generated as part of the project “ABHD11 inhibition and T cell function in autoimmunity” at Swansea University. The DAC will evaluate and approve access requests based on scientific merit and alignment with participant consent. Data requests will be considered from academic researchers and healthcare professionals working on immunology or autoimmunity.

  Dac EGAC50000000750

• CosMX spatial transcriptomics

  This study consists of the spatial transcriptomics analyis data generated by : CosMxTM Human Universal Cell Characterization RNA Panel (1000-plex); NanoString, USA for n=4 SLD-HCC and n=4 non-SLD-HCC. The goal of this data is to compare SLD-HCC vs non-SLD-HCC as well as response to immunotherapy

  Dataset EGAD50000001507

• scRNAseq + TCRseq of n-irAE patients

  Here we performed multimodal analysis (5'scRNAseq and TCR-seq) on PBMCs from cancer patients developing or not neurological adverse events (n-irAEs) following immune checkpoint inhibition (ICI) treatment.

  Study EGAS50000000603

• Whole genome sequence analysis in patients with primary central nervous system lymphomas

  We performed target amplicon sequencing analysis in 28 patients with primary central nervous system lymphomas using target capture technology (NGS) on Cancer Panel to explore molecular targets.

  Study JGAS000258

• Target sequencing of ROS1-rearranged lung cancer patients

  We performed target capture sequencing of ROS1-rearranged non-small cell lung cancer patients to develop and examine the efficacy of new molecular targeted drug against ROS1 tyrosine kinase.

  Study JGAS000189

• Building a Database of Genomic Structural Variants in Japanese population

  Purified genomic DNA was purchased from Japanese B cell DNA bank; We sequenced those genomic DNAs using PacBio and 10X Genomics sequencing technologies, and analyzed genomic structural variations.

  Study JGAS000173

• Genomic Structural Variants in Japanese Malignant mesothelioma patients

  We extracted genomic DNAs from established mesothelioma cell lines from Japanese malignant mesothelioma patients. We sequenced those genomic DNAs using 10X Genomics sequencing technologies, and analyzed genomic structural variations.

  Study JGAS000176

• The elucidation of molecular mechanisms of hematopoietic stem cells focusing on paroxysmal nocturnal hemoglobinuria (PNH)-type cells

  To elucidate the pathogenicity of aplastic anemia, we conducted exome seqence analysis in 5 patients with aplastic anemia with uniparental disomy in 6p.

  Study JGAS000094

• Building a Database of Genomic Structural Variants in Japanese population

  Purified genomic DNA was purchased from Japanese B cell DNA bank; We sequenced those genomic DNAs using PacBio Sequel and Sequel II and analyzed genomic structural variations.

  Study JGAS000286

• Identification of the genes associated with EGFR-mutant lung cancer

  To gain an insight into the genetic factors underlying the carcinogenesis of EGFR-mutant lung adenocarcinoma, we sequenced the exomes in peripheral-blood DNA from the patients.

  Study JGAS000129

• scD&D-seq of mobilized PBMC from a healthy individual having IDH2 R140Q CHIP

  Single-cell D&D-seq profiles from a mobilized CHIP (clonal hematopoiesis of indeterminate potential) PBMC sample (2 replicates) co-profiled with IDH2 R140Q GoT-ChA.

  Study EGAS50000001590

• BCAC TIIC Data

  Data on spatially-resolved tissue infiltrating immune cells (TIICs) from 17,265 breast cancer patients of European descent, from studies participating in the Breast Cancer Association Consortium, together with linked clinical data.

  Study EGAS50000001477

• PDAC clinical phenotype data with CA19-9 and Lewis antigen status

  This dataset contains individual-level clinical phenotype data from patients with pancreatic ductal adenocarcinoma, including CA19-9 measurements, Lewis antigen status, and relevant clinicopathological variables. Data were generated as part of an ethically approved study and are available under controlled access.

  Dataset EGAD50000002254

• Error-Corrected Next-Generation Sequencing Rectal Mucus

  Error-corrected next-generation sequencing of rectal mucus samples from patients suspected to have colorectal cancer. This is 1 of 4 sequencing experiments on the same sample type.

  Study EGAS50000001398

• Sequencing_of_patient_samples_who_received_immune_checkpoint_inhibition___WES___NKI

  DNA and RNA isolated from FFPE blocks of patients who received immune checkpoint inhibition (ICI) are sequenced with the aim to identify therapeutically tractable vulnerabilities in tumors to prevent ICI resistance.

  Study EGAS00001003154

• Colon adenomas and adenocarcinomas and matched mucosae

  Whole exome sequencing in sporadic colorectal cancers (CRC) and advanced adenomas (Ad-As), and their paired healthy mucosa, for a deeper understanding of the biology of this cancer.

  Study EGAS00001007255

• RNA-seq of CD34+ HSPCs from LRMDS patients

  To profile transcriptional alterations of HSPCs in LR-MDS patients, 7AAD−CD45+Lin-CD235a−CD34+ cells were isolated from healthy donors and LR-MDS patients for RNA sequencing.

  Study EGAS00001008182

• Whole exome sequencing (bam files) of 55 samples of myxofibrosarcoma and 44 matched pairs

  Myxofibrosarcoma (MFS) is a rare subtype of sarcomas in the elderly, whose genetic basis is poorly understood. To elucidate it, the whole exome sequence was performed.

  Study EGAS00001005442

• S_CORT_Stratification_in_COloRecTal_cancer_

  Colorectal cancer samples will be submitted for Illumina sequencing using a custom capture of 116 genes implicated in colorectal tumourigenesis. Driver mutations will be detected and ultimately correlated with phenotypic data.

  Study EGAS00001001521

• Genomic landscape of Chordoid Glioma

  Chordoid glioma (ChG) is a characteristic, slow growing and well-circumscribed diencephalic tumor, whose mutational landscape is unknown. We analyzed primary chordoid glioma samples by whole exome sequencing, RNAseq

  Study EGAS00001002433

• ChIP_sequencing_in_Cancer_Cell_Lines

  The project is to evaluate the genomic binding sites of the histone demethylase JARID1C. This gene was recently identified in CGP as a novel recessive cancer gene in human renal cell carcinoma.

  Study EGAS00001000203

• Covid19 WGS Raw Read files

  The Samples were collected from Saint James's Hospital, Dublin and after informed consent Extracted Genomic DNA samples were prepared and sequenced using the Automated Illumina TruSeq PCR-free methodology.

  Study EGAS00001007106

• Combined genetic and transcriptome analysis of patients with Systemic Lupus Erythematosus (SLE)

  A comprehensive profiling of the genomic architecture of Systemic Lupus Erythematosus (SLE) by combining genetic and transscriptomic analysis by RNA-seq.

  Study EGAS00001003662