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• Patient-derived organoids identify tailored therapeutic options and determinants of plasticity in sarcomatoid urothelial bladder cancer

  Study EGAS00001007430

• Panamanian genotype data

  84 Indigenous and admixed individuals from Panama genotyped with Axiom Human Origins (Affymetrix)

  Dataset EGAD00010002473

• HomoCulturGen

  86 samples from four human populations: two from Central Asia and two from Southeast Asia

  Dataset EGAD00010002663

• Germany-Immuno

  Germany Multiple Sclerosis cases and normal controls

  Dataset EGAD00010002044

• Belgium-Immuno

  Belgium Multiple Sclerosis cases and normal controls

  Dataset EGAD00010002045

• France-Immuno

  France Multiple Sclerosis cases and normal controls

  Dataset EGAD00010002046

• AUSNZ-Immuno

  Australia and New Zealand Multiple Sclerosis case

  Dataset EGAD00010002047

• OGVP_HC24_Controls

  Healthy adult volunteers and newborns recruited in various countries across Oceania.

  Dataset EGAD00010000953

• BCC exomes and transcriptomes

  Dataset EGAD00001001857

• Summary data from case control analysis

  Summary data from GWAS analysis on 856 cases and 2836 control

  Dataset EGAD00000000115

• EGAD00000000059

  Aggregate results from 43 Carbamazepine-induced hypersensitivity syndrome patients and 1296 1958 British Birth Cohort control samples

  Dataset EGAD00000000059

• EGAD00000000058

  Aggregate results from 22 Carbamazepine-induced hypersensitivity syndrome patients and 2691 UK National Blood Service (NBS) control samples

  Dataset EGAD00000000058

• Unmatched WGS from bone marrow samples of 5 chr21 amplified blast phase myeloproliferative neoplasm patients

  We describe recurrent chromothripsis of chromosome 21 in a subset of patients in blast phase of a myeloproliferative neoplasm (BP-MPN), which alongside other structural variants leads to amplification of a region of chromosome 21 in ~25% of patients (‘chr21amp’). Chr21amp BP-MPN has a particularly aggressive and treatment-resistant phenotype. Here we provide high-depth whole genome sequencing (WGS) in five chr21amp BP-MPN cases, to a median coverage of 81x [range 77-86] and purity 79% [range 58-88%].

  Dataset EGAD00001011280

• Whole exome sequencing of patients with esophageal squamous cell carcinoma receiving chemoradiotherapy

  We performed multi-region whole exome sequencing (WES) of pre-treatment and recurrent esophageal cancer receiving chemoradiotherapy in order to characterize clonal evolution of treatment resistant clones. Furthermore, additional solitary pre-treatment tumor samples were subjected to WES to detect biomarkers predicting clinical outcome.

  Study JGAS000227

• DKFZ-HIPO Project H021/NCT MASTER

  Clinical genome and transcriptome sequencing in younger adults with advanced-stage cancer across all histologies: DKFZ-HIPO Project H021 (http://www.hipo-heidelberg.org/hipo2/index.php/menu-item-2/32-021-prospective-genetic-characterization-of-tumors-from-individual-patients-of-special-interest) / NCT MASTER (http://www.nct-heidelberg.de/forschung/nct-master.html)

  Study EGAS00001000948

• NAR-GAB 2025 deposit data

  Paired-end whole-exome sequencing data derived from Illumina hybrid-capture experiments (Agilent SureSelect Human All Exon kits). Six human probands with rare diseases; one sample per subject. Sequencing reads from each individual were processed into analysis-ready gVCF files following standard best-practice pipelines, including alignment, duplicate marking, base quality calibration, and variant calling. All gVCF files are encrypted using Crypt4GH and are available under controlled access through our DAC in accordance with a strict DUO-based policy.

  Dataset EGAD50000002100

• Non-coding mutations drive persistence of a founder pre-leukemic clone which initiates late relapse in T-ALL

  T-ALL relapse usually occurs early but can occur much later, which has been suggested to represent a de novo leukemia. However, we conclusively demonstrate late relapse can evolve from a pre-leukemic subclone harbouring a non-coding mutation that evades initial chemotherapy. Data include 19 WGS samples: - 5 cases with presentation, relapse and remission (germline) samples - 2 cases with presentation and relapse samples, but not remission (germline)

  Dataset EGAD50000000174

• RNA-seq of PDAC patient-derived xenograft tumors

  This dataset contains single cell RNA-seq data of stromal cells derived from two PDX models (N = 2 in total) and bulk RNA-seq data of two PDX models treated with gemcitabine and our novel antibody-drug conjugate, C6-EBET (N = 59 in total). Bulk RNA-seq experiments were performed with Agilent SureSelect Strand Specific RNA Library Prep Kit (Agilent). Single cell RNA-seq experiments were performed with Chromium Single Cell 3' Reagent Kits v2 Chemistry (10x Genomics).

  Dataset EGAD00001010130

• WGS and RNA-Seq data from a GBM patient PT-SS3647

  WGS and RNA-Seq data from a GBM patient PT-SS3647

  Dataset EGAD00001008530

• WGS and RNA-Seq data from a GBM patient PT-SJ5453

  WGS and RNA-Seq data from a GBM patient PT-SJ5453

  Dataset EGAD00001008529

• WGS and RNA-Seq data from a GBM patient PT-PV2594

  WGS and RNA-Seq data from a GBM patient PT-PV2594

  Dataset EGAD00001008526

• Mongolia and Western Dataset

  Total collection of Samples. Exome sequencing and RNAseq from Mongolia and Western HCC samples.

  Dataset EGAD00001007830

• Chair of Experimental Medicine and Therapy Research Regensburg DAC

  Dac EGAC00001001699

• DupiAERD DAC

  DAC to regulate access to RNA sequencing data of NERD patients with dupilumab treatment before and after aspirin provocation.

  Dac EGAC50000000273

• RNA sequencing of in vitro generated suppressive myeloid cells using parental and Sialidase expressing A549 cancer cell lines

  Study EGAS00001007618

• Smoking-dependent expression alterations in nasal epithelium reveal immune impairment linked to germline variation and lung cancer risk

  Study EGAS00001006137

• RNA-seq on neuroblastoma PDX model COG-N-519 treated with control miR-1283 and test miR-99b-5p mimics

  Study EGAS00001005368

• transcriptome analysis of NK cells sorted from PBMCs at baseline and after addition of a T cell dependent bispecific antibody (TDB)

  Study EGAS00001006914

• Genomic and immune signatures predict clinical outcome in newly diagnosed multiple myeloma treated with immunotherapy regimens

  Study EGAS00001007404

• SNParray_CASCADE

  Tumor and matched normal DNA profiling by SNP array

  Dataset EGAD00010002398

• SNParray_MOCOG

  Tumor and matched normal DNA profiling by SNP array

  Dataset EGAD00010002359

• NSAID-LIV

  1000G Phase 3 Imputed cases and controls from NSAID-induced PUD study

  Dataset EGAD00010001422

• 1506_Methylation_M.vd.Berge

  DNA methylation in bronchial biopsies of asthmatics, asthma in remission and healthy subjects

  Dataset EGAD00010001731

• Thai Cases

  252 dengue fever patients and 159 dengue shock syndrome patients

  Dataset EGAD00010001487

• OCAC OncoArray data

  Germline genotype data on 56,479 ovarian cancer cases and controls

  Dataset EGAD00010001192

• EGAD00010000474

  blood-based gene expression from breast cancer cases and age-matched controls in case-control serie 2 (CC2)

  Dataset EGAD00010000474

• EGAD00010000476

  blood-based gene expression from breast cancer cases and age-matched controls in case-control serie 1 (CC1)

  Dataset EGAD00010000476

• EGAD00010000478

  blood-based gene expression from breast cancer cases and age-matched controls in case-control serie 3 (CC3)

  Dataset EGAD00010000478

• H3Africa TrypanoGEN+ Phenotype

  TrypanoGEN+ phenotype data containing 183 samples from DRC, Malawi and Uganda.

  Dataset EGAD00001011348

• PDAC CT WEX PDX1

  Whole Exome Sequencing on PDAC PDX1 parental sample and 12 clones.

  Dataset EGAD00001004580

• Cell subtypes subsets from subcortical MS snRNA-seq atlas

  Curated subsetting of cell subtypes derived from the 9 principal cell types within our subcortical Multiple Sclerosis (MS) lesions snRNA-seq atlas.

  Dataset EGAD50000000522

• thraruk-G-1

  Resolving the Genetic Architecture of Aseptic Loosening After Total Hip Replacement

  Dataset EGAD00010001289

• Mutation analysis of 77 genes in cfDNA from metastatic CRC patients

  Aligned NGS data (BAM) of 77 frequently mutated genes in cancer using the AVENIO Expanded platform.

  Dataset EGAD00001010294

• Exome Sequencing of 44 subjects with very severe or fatal COVID-19

  In this study, the DNA of 44 subjects with severe COVID-19 have been sequenced in order to explore rare genetic variants.

  Dataset EGAD00001008993

• Human tumor bulk RNA-seq

  We profiled 9 high-grade gliomas patient tumor samples by bulk RNA-seq. The raw fastqs are provided.

  Dataset EGAD00001008348

• Whole-genome-seqeuncing IMFT

  Whole-genome sequencing of IMFT tumor samples from 24 participants in the clinical phase II trial EORTC 90101 “CREATE” (CREATE IMFT cohort)

  Dataset EGAD00001007804

• Phenotypic characterisation of LRRN4CL over-expression

  This study aims to use RNAseq to identify differentially expressed transcripts in human melanoma cells that over-express the cell surface protein, LRRN4CL, relative to empty-vector control cells, to provide mechanistic insight into how LRRN4CL over-expression confers enhanced pulmonary metastatic colonisation abilities.

  Dataset EGAD00001006249

• HEMa_LP

  This dataset contain WGBS sequencing result of HEMa_LP. The cells were cultured in Medium 254 supplemented with PMA-Free Human Melanocyte Growth Supplement-2 (HMGS-2) under 37°C,5% CO2.

  Dataset EGAD00001005486

• cHCC-ICC RNAseq

  The RNA-seq data of 97 tumor samples from 77 cHCC-ICC cases, data of two other HCC tumor samples were also included.

  Dataset EGAD00001005182

• Whole Genome Sequencing of 18 sequential samples from 3 CLL patients

  Whole Genome Sequencing to track subclonal heterogeneity in 18 samples from 3 Chronic Lymphocytic Leukemia patients subjected to repeated cycles of therapy. NOTE: There are only 12 BAM files available to download. The other 6 files are missing.

  Dataset EGAD00001000972