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• COVID-19 progression and convalescence in common variable immunodeficiency patients

  Longitudinal analysis of single-cell RNAseq datasets of PBMCs from COVID-19 CVID patients and controls.

  Dataset EGAD50000000543

• Exome sequencing of FFPE and patient-derived cultures

  Exome sequencing of FFPE and patient-derived cultures from patients enrolled in clinical study NCT03860376

  Dataset EGAD50000000245

• Transcriptome sequencing of FFPE and patient-derived cultures

  Transcriptome sequencing of FFPE and patient-derived cultures from clinical study NCT03860376

  Dataset EGAD50000000246

• Gene expression from human iPSC derived cortical neurons

  Gene expression from icas9 human iPSC derived cortical neurons treated with and without doxycycline

  Study EGAS00001004782

• Expressed_fusion_transcripts_in_rare_bone_tumours

  mRNA-Seq on total RNA from primary osteoblastomas and phosphaturic mesenchymal tumours, focussing on fusion transcript expression

  Study EGAS00001000763

• Comparison of HCC cell lines and primary HCCs

  Whole genome sequencing (30X) using Hiseq X TEN on 4 HCC cell lines, primary HCCs and early-passage PDCs

  Dataset EGAD00001001995

• Genomic Analysis of Mucinous Tumours (GAMuT)

  Sequencing data from primary mucinous ovarian carcinomas, benign and borderline mucinous tumours and extra-ovarian mucinous metastases.

  Dataset EGAD00001004851

• Dateset of clonal evolution in myelofibrosis

  This dataset includes bam files of tumor and paired normal samples derived from 15 patients with myelofibrosis. Tumor samples includes those before and after treatment.

  Dataset EGAD00001005282

• Whole genome sequencing and genotyping of samples from BFMOS (Mossi from Burkina faso)

  Whole genome sequencing and genotyping of samples from BFMOS (Mossi from Burkina faso)

  Dataset EGAD00001005011

• Sequence of breast cancer bone metastases PDX from WES

  Exome sequencing analyses obtained from 11 samples of PDX engrafted with bone metastases, match primary tumors and/or metastases and normal tissus.

  Dataset EGAD00001006071

• ALI culture bronchial cells and alveolar lung surgical resection scRNA-Seq

  ALI culture bronchial cells and alveolar lung surgical resection scRNA-Seq

  Dataset EGAD00001006185

• Citrate synthase novel variant rewires TCA cycle to promote colorectal cancer progression

  H3K4me3, IgG, and Input ChIP-seq in overexpression of pLV Control, CS-FL and CS-ΔEx4 in SW1116 cells

  Dataset EGAD00001015543

• Semmelweis University - Biophysics Data Access Committee

  This DAC belongs to the dataset entitled: Next generation sequencing on cardiac samples in Hungarian patients of dilated cardiomyopathy.

  Dac EGAC50000000053

• Reproducibility of 10x Genomics single cell RNA sequencing method in the immune cell environment

  Study EGAS00001005905

• Metabolic requirements of the metastasis-initiating tumour cell population using oral squamous cell carcinoma (OSCC) as a model system

  Study EGAS00001004765

• cfDNA shallow Whole-Genome sequencing - healthy donors

  sWGS of the blood samples from 14 (fourteen) healthy donors

  Dataset EGAD50000001860

• BCG prime DNA methylation data

  This dataset contains the DNA methylation data of 384 samples from individuals with one or more comorbidities

  Dataset EGAD00010002767

• KIR region SNP genotypes

  KIR gene content imputation from single-nucleotide polymorphisms in the Finnish population

  Dataset EGAD00010002206

• Trained immunity DNA methylation data

  This dataset contains the DNA methylation data of 904 samples from Dutch healthy individuals.

  Dataset EGAD00010002738

• Ethiopia_Genome_Project_high_coverage_vcf

  Integrated callset of high coverage Ethiopian genomes from the Pagani et al. 2015 AJHG paper (doi: http://dx.doi.org/10.1016/j.ajhg.2015.04.019)

  Dataset EGAD00001003294

• AI_NF1glioma_WES_control

  The dataset includes 43 matched normal samples from 43 NF1-glioma patients profiled by Whole Exome Sequencing.

  Dataset EGAD00001004374

• Leicester Mesothelioma Research Omics Dataset Committee

  This Data Access Committee consists of the mesothelioma research group led by Professor Dean Fennell.

  Dac EGAC50000000965

• CMML_Bulk_WGS

  Whole genome sequencing to determine HSC phylogeny in MDS and clonal haematopoiesis patients undergoing treatment with hypomethylating agents.

  Study EGAS00001008237

• Human prostate cancer plasma cfRNA study - raw data

  mRNA capture sequencing on plasma sample from 132 prostate cancer patients and 48 control donors.

  Study EGAS50000001265

• snRNA-sequencing data from 3 FSHD and 1 control multinucleated myotube cell cultures

  snRNA-sequencing data from 3 FSHD and 1 control multinucleated myotube cell cultures

  Dataset EGAD50000000207

• 10X Chromium 3' scRNA sequencing of pre- and on-treatment HNSCC biopsy samples

  We performed 10X Chromium 3' scRNA sequencing of 23 pre- and on-treatment HNSCC biopsy samples.

  Dataset EGAD50000000055

• 10X Chromium 5' scRNA and scTCR sequencing of on-treatment HNSCC PBMC samples

  We performed 10X Chromium 5' scRNA and scTCR sequencing on 4 on-treatment HNSCC PBMC samples.

  Dataset EGAD50000000054

• Whole exome sequencing Data from a child with ALPI deficiency and parents

  This dataset contains raw sequences (BAM files) of P1 trio: mother, father and affected child (P1). Whole exome sequencing (WES).

  Dataset EGAD00001004048

• Whole genome sequencing of acral melanomas

  We conducted whole genome sequencing of 5 acral melanoma genomes and their matched DNA from blood.

  Study EGAS00001000486

• Lung_Progression_versus_Regression_Whole_Genome_Sequencing

  Around 50 samples of pre-invasive lung cancer lesions showing subsequent clinical and pathological progression or regression

  Study EGAS00001000837

• PREDICT

  PREDICT/Predicting individual response and resistance to VEGFR/mTOR pathway therapeutic intervention using biomarkers discovered through tumour functional genomics.

  Study EGAS00001000094

• The_identification_of_genetic_vulnerabilities_in_head_and_neck_cancers_for_the_development_of_novel_therapies

  CRISPR/Cas9 lethality screens in a set of Asian head and neck cancer cell lines to identify novel targets.

  Study EGAS00001002204

• Multi-omics Profiling of Asian Breast Cancers

  Whole exome and transcriptome sequencing data of primary tumors from 178 Korean breast cancer patients.

  Study EGAS00001002621

• ImmunoAgeing_Colonies_WGS

  Aim to determine age at acquisition of clonal haematopoiesis mutations, clonal architecture, and dynamics of clonal expansions.

  Study EGAS00001004280

• FGFP (N=150) and TR-MDD (N=7) shotgun sequencing samples

  FGFP (Flemish Gut Flora Project, N=100) and TR-MDD (Treatment-Resistant Major Depression Disorder, N=7) shotgun sequencing samples

  Dataset EGAD00001004454

• ATAC Sequencing of 4 CLL patient samples

  ATAC Sequencing of 4 CLL patient samples investigating differences by IGHV mutation status and trisomy 12.

  Study EGAS00001006206

• BLUEPRINT transcriptional profiling of normal and neoplastic plasma cells

  RNAseq profile of purified plasma cells from multiple myeloma patients and tonsils of healthy donors

  Dataset EGAD00001001212

• MYC and MINCR-regulated lncRNAs in hT-RPE-MycER cells

  RNA-sequencing data from teh hT-RPE-MycER cell line after MYC activation and after MINCR knock-down in conditions of MYC ON or OFF

  Dataset EGAD00001001598

• Whole transcriptome sequencing of untreated and castration resistant prostate cancer

  Whole transcriptome sequencing of 28 untreated prostate cancers, 13 castration resistant prostate cancers, and 12 benign prostatic hyperplasias.

  Dataset EGAD00001000609

• Small RNA sequencing of untreated and castration resistant prostate cancer

  Small RNA sequencing of 28 untreated prostate cancers, 12 castration resistant prostate cancers, and 3 benign prostatic hyperplasias.

  Dataset EGAD00001000611

• Exome sequencing of short SGA children with IGF-I and insulin resistance

  Exome sequencing of short SGA children with IGF-I and insulin resistance. Collaboration with Professor David Dunger, University of Cambridge. Funded by NIHR.

  Dataset EGAD00001002208

• BAP1 sequence of uveal melanoma and mesothelioma samples

  Detection of BAP1 mutations in DNA from uveal melanoma and mesothelioma samples.

  Dataset EGAD00001002229

• 108 samples liver cancer and normal controls (54 pairs), whole exome sequencing

  liver cancer paired with normal controls, viral and non-viral origin

  Dataset EGAD00001006005

• whole genome sequencing of breast cancer cell lines and patient derived xenograft models

  whole genome sequencing of six commonly used breast cancer cell lines and six patient derived xenograft models

  Dataset EGAD00001008802

• smallRNA sequencing data from PAXgene blood from control and MCI individuals

  smallRNA sequencing from healthy individuals and MCI patients, along with phenotypic information.

  Dataset EGAD00001008153

• ADAPTeR Study: TCRseq data from ccRCC patients

  ADAPTeR study multi-region TCRseq of pre and post nivolumab tumour and PBMC samples

  Dataset EGAD00001008165

• Long non-coding RNA capture

  Capture lncRNA and totalRNA sequencing of various sample types (including plasma, FFPE and high quality RNA).

  Dataset EGAD00001007819

• Treated and control Patient Derived Xenografts of colorectal cancer (CRC) samples

  Bank of treateed and control PDXs metastastic colorectal cancer sample RNAseq

  Dataset EGAD00001010022

• ATAC-seq of cohesin-mutated and -wildtype adult AMLs

  ATAC-seq (Illumina TDE1 Transposase) to profile accessible chromatin regions of cohesin-mutated (STAG2 or RAD21 mutations) and -wildtype adult AMLs.

  Dataset EGAD00001011267

• WGS short read and 10X linked read sequencing of HR Deficient breast cancers

  A set of tumor/normal paired sequencing experiments, performed in short read WGS and 10X linked read whole genomes. BAM files aligned to hg19 are provided. Sample Alias number and Subject ID reflects patient of origin. T/N distinction discriminates between tumor and normal (peripheral blood) tissue.

  Dataset EGAD00001010326