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• Cancer Genomics of the Kidney - Targeted Sequencing

  Dac EGAC00001003091

• Annie Huang and the Hospital for Sick Children

  Dac EGAC01000000015

• Data Access Committee for the Berardi group

  Dac EGAC00001003392

• DAC for the study EGASXXX

  Dac EGAC00001002746

• Data access committee for the HOMOCULTURGEN dataset

  Dac EGAC00001003485

• DAC for the study EGAS00001007247

  Dac EGAC00001003262

• Spatial Dynamics of the Developing Human Heart

  Dac EGAC50000000616

• DAC_iCope

  DAC for the iCope submission

  Dac EGAC50000000696

• DAC for Rare Disease Studies from the Broad Institute

  Dac EGAC00001000566

• THE SAHEL 2.5 MILLION SNP ARRAY

  Dac EGAC00001000427

• The NOWAC study Data Access Committee

  Dac EGAC00001000521

• The Sample and Data Access Committee (SDAC) of CARTaGENE

  Dac EGAC00001000525

• DAC for the Prostate Cancer Lymph Node dataset

  Dac EGAC00001000586

• The Ovarian Cancer Association Consortium Data Access Committee

  Dac EGAC00001000616

• The Kibbutzim Family study (KFS) data access committee

  Dac EGAC00001000805

• Genomic Heterogeneity and the Small Renal Mass

  Dac EGAC00001000875

• Present-day genomics from the Eurasian steppe

  Dac EGAC00001000878

• DAC for the study EGAS00001003368

  Dac EGAC00001001270

• DAC for the study EGAS00001004301

  Dac EGAC00001001571

• DAC the Tel-Aviv Medical Center Neurosurgery dept

  Dac EGAC00001002176

• Data access committee for the ADJUVANT biomarker study

  Dac EGAC00001002333

• The Solomon Islands: Human Origins array genotype data

  Dac EGAC00001002588

• The Ernest and Helen Scott Haematological Research Institute

  Dac EGAC00001002616

• Data Access Committee for the Radovanovic group

  Dac EGAC00001002942

• The Swedish Childhood Tumor Biobank DAC

  Dac EGAC50000000095

• Hi-C on the OCIAML-2 Cell Line

  Study EGAS00001004743

• Age_Validation

  Rounded chronological age of the participants

  Dataset EGAD00010002753

• Age_TrainTest

  Rounded chronological age of the participants

  Dataset EGAD00010002755

• The Genomic Landscape of Juvenile Myelomonocytic Leukemia

  This study analyzed samples from 29 patients with juvenile myelomonocytic leukemia (JMML) using whole exome sequencing. Each patient had a paired germline tissue along with a diagnostic leukemia sample. Germline tissue types included buccal mucosa, cordblood, Epstein-Barr virus immortalized cell lines and fibroblasts from either skin or bone marrow. Leukemia samples were either blood or bone marrow. Seven of the 29 patients also had a relapsed leukemia sample available for exome analysis.

  Study phs000973

• Elucidation of the association between viruses and autoimmune diseases and COVID-19

  We determined the presence or absence of endogenous herpesvirus 6 (eHHV-6) and calculated annelovirus levels from whole genome sequencing of 2,238 patients with autoimmune diseases and 2,919 controls. We performed genome-wide association analysis using WGS of 22 eHHV-6B-positive cases and -negative cases. Single-cell RNA sequencing was performed using human peripheral blood mononuclear cells from 3 eHHV-6B-positive SLE patients and 5 -negative SLE patients.

  Study JGAS000741

• The cellular state space of AML unveils novel NPM1 subtypes with distinct clinical outcomes and immune evasion properties

  Acute myeloid leukemia (AML) is a genetically and cellularly heterogeneous disease. We characterized 120 AMLs using bulk genomic and transcriptomic analyses (WES, MP-WGS, RNA-seq), and single-cell RNA sequencing (scRNA-seq). Our results reveal an extensive cellular heterogeneity that distorts the bulk transcriptomic profiles. Notably, NPM1 mutated AML could be stratified into two novel, clinically relevant classes (NPM1class I and NPM1class II).

  Study EGAS50000001084

• ProstOmics - Bulk Transcriptomics

  Bulk transcriptomics data from 176 prostate tissue samples (37 patients, 27 with post-surgery relapse) that were acquired using the SENSE mRNA-Seq Library Prep Kit V2 and Illumina NextSeq 500 instrument. The raw transcriptomics data is single-read RNA-seq. The individual samples have information on patient origin and sample type (cancer, cancer-adjacent field-effect normal or normal sample far from cancer). Patient metadata include information of age at surgery, time (months) until reported relapse, pre-surgery PSA and post-surgery T-stage.

  Dataset EGAD50000000604

• Fastq files for the single cell RNAseq data of Follicular lymphoma study

  Fastq files for the single cell RNAseq data of Follicular lymphoma study. This dataset includes the paired single cell RNA sequencing data for 23 samples.

  Dataset EGAD00001008595

• Bone marrow microenvironment of 6 newly diagnosed myeloma patients using 10X Genomics scRNA- and TCR-sequencing

  10X Genomics scRNA- and TCR-sequencing (Chromium Next GEM Single Cell 5’ Reagent Kit v1.1) was performed on the plasma cell depleted mononuclear fraction of bone marrow aspirates from 6 patients with newly diagnosed multiple myeloma. Generated gene expression libraries were paired-end sequenced on the NovaSeq 6000 S2. Generated V(D)J libraries were paired-end sequenced on the NextSeq 550.

  Dataset EGAD00001009270

• WGS of peripheral blood leukocytes from patients with Li-Fraumeni syndrome

  We performed whole genome sequencing on 84 LFS family members from 47 families: 22 with wildtype TP53 and 62 with variant TP53. The variant TP53 cohort consists of 49 individuals who developed cancer and 13 individuals who remain cancer-free; 34 were from 13 families with 2-4 individuals sequenced within a given family and the remaining 28 had no family members sequenced. The wildtype cohort consists of 14 individuals who developed cancer and 8 individuals who are cancer-free, from 6 families.

  Dataset EGAD00001010200

• Transcriptomic analyses of a large cohort of adult B cell acute lyphoblastic leukemia

  Total mononuclear cells (MNC) were isolated from peripheral blood (PB) or bone marrow (BM) samples of 105 Ph-/-/- (B-cell acute lymphoblastic leukemia [B-ALL] triple negative) and 31 Ph+ B-ALL adult patients using Lymphosep (Biowest, Nuaillé, France). A total of 15 samples from healthy subjects were processed including hematopoietic stem-progenitor cells (CD34+) from bone marrow specimens (n = 3), and bone marrow mononuclear cell samples (n = 3) from STEMCELL Technologies (Vancouver, Canada). PB MNC samples (n=5) and cord blood samples (n = 4). CD34+ cells were enriched from cord blood samples by immunomagnetic separation (CD34 MicroBead Kit, Miltenyi Biotec, Bergisch Gladbach, Germany).Libraries were prepared using the TruSight RNA Pan-Cancer Panel Kit (Illumina, San Diego, California, USA), following the manufacturer’s protocol. Sequencing was performed using the Illumina MiSeq instrument.

  Dataset EGAD00001010837

• Exome Recapture and Sequencing of Prospectively Characterized Clinical Specimens From Cancer Patients

  The study cohort comprises samples from patients whose tumors have been prospectively characterized as part of their care at Memorial Sloan Kettering Cancer Center. This includes a variety of distinct tumor type and molecular subtypes.

  Study phs001783

• Comprehensive genomic characterization of early stage bladder cancer - whole exome sequencing data

  For this project about non-muscle invasive bladder cancer (NMIBC), we analysed WES data from 438 patients. The dataset is composed of 876 BAM files: 438 tumor samples and 438 paired blood samples.

  Study EGAS50000000511

• Shared and distinct features of immune checkpoint therapy-induced myocarditis and myositis

  Immune checkpoint therapies (ICTs) can induce life-threatening immune-related adverse events including myocarditis and myositis, which are rare and often concurrent. The molecular pathways and immune subsets underlying these toxicities remain poorly understood.

  Study EGAS00001007511

• Brazilian Genomes

  We generated 2,723 high-coverage whole-genome sequences of Brazilian population from the country’s five geographical regions. This diverse group encompasses individuals from urban and rural settings (including riverine communities) and represents various ethnic backgrounds, including Afro-Brazilians.

  Study EGAS50000000730

• Spatial transcriptomics

  This dataset contains raw sequencing and processed data of spatially resolved transcriptomes. The data were generated with 10x Visium probe-based assay on FFPE tissues of 30 ST-EPN tumour resections. Raw data contain two-lane fastq files of the sequencing. Processed data contain aligned and filtered .h5 counts matrices as well as positional files as generated by 10x SpaceRanger.

  Dataset EGAD50000001876

• ALS-FTD brain motor cortex single-nucleus RNA-seq of NeuN+ nuclei sorted for TDP-43 low vs. high

  A dataset of single-nucleus RNA-seq data of nuclei from the post-mortem human primary motor cortex from patients with ALS-FTD. The nuclei were sorted by flow cytomotetry into NeuN+ (neuronal) TDP-43 low vs. TDP-43 high fractions.

  Dataset EGAD50000002243

• Multi-omic single-nucleus ATAC-seq + RNA-seq of nuclei from the motor cortex of ALS/ALS-FTD patients and unaffected controls

  A multi-omic dataset of single-nucleus paired ATAC-seq + RNA-seq data of nuclei from the post-mortem human primary motor cortex from patients with ALS/ALS-FTD and unaffected controls.

  Dataset EGAD50000002240

• Single-cell DNA sequencing dataset of aplastic anemia and RCC (31 samples)

  This dataset contains raw single-cell DNA sequencing data generated from 31 patients with aplastic anemia using the Mission Bio Tapestri platform. Libraries were prepared with a targeted DNA amplicon panel and sequenced on an Illumina platform. These raw data capture single-cell variant profiles and clonal architecture and serve as the basis for downstream analysis of somatic mutations and clonal hematopoiesis.

  Dataset EGAD50000002189

• Total RNAseq data from 8 patients with muscle invasive bladder cancer

  For this dataset we performed total RNAseq on blood samples from 8 patients with muscle invasive bladder cancer. The data consists of 8 sets of paired fastq files with accompanying UMI fastq files. Sequenced on the Illumina NoveSeq6000 platform using S2 flow cells (v1.5,2x150 cycles), with a mean yield of 313 million reads.

  Dataset EGAD50000001380

• Head and Neck Organoid Biobank cohort, Issing et. al., 2025, RNA + WES data

  This dataset contains the raw fastq files of RNA and whole exome sequencing of the head and neck organoid biobank. For RNA sequencing, 41 organoid samples collected at different timepoints as well as before and after genetic modification are included. For WES, 25 samples of early organoid cultures or matching tumor tissues are included.

  Dataset EGAD50000001733

• Dataset for WGS and RNA samples of acute myeloid leukemia with MNX1 expression

  This dataset contains 10 samples of WGS, ATAC, 4C and RNAseq samples of patients with acute myeloid leukemia. The sequencing was performed on Illumina HiSeq 4000, 2000 and HiSeq X using Illumina TruSeq Nano DNA and Agilent Strand Specific RNA Kits. The sequencing was always paired.

  Dataset EGAD50000001098

• (h)MeDIP-Seq of high-risk prostate cancer

  Immunoprecipitation of methylated and hydroxymethylated DNA was performed on DNA isolated from tumoral and non-tumoral prostate tissue of patients with high-risk disease. Samples were sequenced on the Illumina HiSeq as 50 bp single end.

  Study EGAS00001001019

• A spatiotemporal organ-wide gene expression and cell atlas of the developing human heart

  Dataset includes 2 scRNA-seq samples from a 6.5-7 post-conception weeks human embryonic heart and 19 samples from 4.5-9 post-conception weeks human embryonic hearts analyzed with the Spatial Transcriptomics method. H&E stains can be sent if requested.

  Dataset EGAD00001005468

• NIHR BioResource Rare Diseases WGS project - Hypertrophic Cardiomyopathy (HCM) Rare Disease domain (VCF data)

  Short read whole genome sequencing (WGS) VCF files for the NIHR BioResource Rare Diseases WGS project – Participants from the Hypertrophic Cardiomyopathy (HCM) Rare Disease domain

  Dataset EGAD00001007885