Search Results - EGA European Genome-Phenome Archive

Single cell RNAseq of PBMC from bladder cancer patients

This dataset contains single cell RNA sequencing data of PBMC samples from 10 bladder cancer patients. cDNAs and single cell RNA libraries were prepared following manufacturer’s user guide (10x Genomics). Each library was sequenced in HiSeq4000 (Illumina) to achieve ~300 million reads following manufacturer’s sequencing specification.

Dataset EGAD00001005481

Reconstruction of complex rearrangement patterns causing the initiation of clear cell renal cell carcinoma.

The genomic hallmark of clear cell renal cell carcinoma is the loss of the short arm of chromosome three. This appears to be the earliest genomic event in the formation of these cancers. Often chromosome 3 is lost at the same time as part of chromosome 5 is duplicated via an unbalanced translocation, often with features consistent with focal chromothripsis. In this study, we sought to reconstruct the chromothriptic event that underlies the initiation of kidney cancer. We used long read sequencing (promethION, Oxford Nanopore Technologies) of patient tumour-derived DNA to elucidate how a single cell division error can generate cancer genome complexity.

Dataset EGAD00001005495

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Single cell RNAseq of PBMC from bladder cancer patients

Reconstruction of complex rearrangement patterns causing the initiation of clear cell renal cell carcinoma.

Genome and transcriptome sequence data from a lung carcinoma patient

Genome and transcriptome sequence data from a pancreatic ductal adenocarcinoma patient

Genome and transcriptome sequence data from a pancreatic cancer patient

Genome and transcriptome sequence data from a cervical adenocarcinoma patient

Genome and transcriptome sequence data from a sex-cord stromal tumor patient

Genome and transcriptome sequence data from a pancreatic adenocarcinoma patient

Genome and transcriptome sequence data from an endometrioid ovary carcinoma patient

Genome and transcriptome sequence data from a metastatic breast cancer patient

Genome and transcriptome sequence data from a pancreatic cancer patient

Genome and transcriptome sequence data from a pancreatic cancer patient

Genome and transcriptome sequence data from a pancreatic cancer patient

Genome and transcriptome sequence data from a pancreatic cancer patient

Genome and transcriptome sequence data from a pancreatic cancer patient

Genome and transcriptome sequence data from a pancreatic cancer patient

Genome and transcriptome sequence data from a transformed diffuse large B cell lymphoma patient

Genome and transcriptome sequence data from an osteosarcoma patient

Genome and transcriptome sequence data from a chordoma patient

Genome and transcriptome sequence data from a cervical squamous cell carcinoma patient

Genome and transcriptome sequence data from a colorectal cancer patient

Genome and transcriptome sequence data from a pancreatic cancer patient

Genome and transcriptome sequence data from a colorectal adenocarcinoma patient

Genome and transcriptome sequence data from a malignant epithelial mesothelioma (THR) patient

Genome and transcriptome sequence data from a melanoma patient

Genome and transcriptome sequence data from an ovarian cystadenocarcinoma low grade patient

Genome and transcriptome sequence data from a colorectal adenocarcinoma patient

Genome and transcriptome sequence data from a pancreatic adenocarcinoma patient

Genome and transcriptome sequence data from a malignant choroid melanoma patient

Genome and transcriptome sequence data from a pancreatic adenocarcinoma patient

Genome and transcriptome sequence data from a large intestine-colon cancer patient

Genome and transcriptome sequence data from a colorectal adenocarcinoma patient

Genome and transcriptome sequence data from a pancreatic ductal adenocarcinoma patient

Genome and transcriptome sequence data from a thyroid hurthle cell carcinoma patient

Genome and transcriptome sequence data from a metastatic pancreatic adenocarcinoma patient

Genome and transcriptome sequence data from a pancreatic cancer patient

Genome and transcriptome sequence data from a cecum adenocarcinoma patient

Genome and transcriptome sequence data from a pancreatic cancer patient

Genome and transcriptome sequence data from a metastatic adrenocortical cancer patient

Genome and transcriptome sequence data from a malignant peripheral nerve sheath tumor patient

Genome and transcriptome sequence data from an endometrial stromal sarcoma patient

Genome and transcriptome sequence data from a hemangioma patient

Genome and transcriptome sequence data from a pancreatic ductal adenocarcinoma patient

Genome and transcriptome sequence data from a pancreatic cancer patient

Genome and transcriptome sequence data from an alveolar soft part sarcoma patient

Genome and transcriptome sequence data from a gastroesophageal junction adenocarcinoma patient

Genome and transcriptome sequence data from a colon adenocarcinoma patient

Genome and transcriptome sequence data from an unknown tissue unknown histology patient

Genome and transcriptome sequence data from an osteosarcoma patient

Genome and transcriptome sequence data from a pancreatic adenocarcinoma patient